Why is there a Vitamin K but no Vitamin F?

The birth of the multivitamin

In 1912, biochemist Kazimierz Funk, often anglicized as Casimir Funk, proposed that there existed an essential nutrient in food that could prevent deficiency diseases, such as scurvy or rickets. This article explores the origin of the multivitamin, an invention that has garnished...

Vitamins are micronutrients human bodies need but don't naturally produce

Each vitamin is found in specific portions of a normal human diet and supports normal human functioning in distinct ways. Vitamin A is found in red meat, carrots, and potatoes and supports vision and skin health, while Vitamin D (common in fish and mushrooms) helps absorb calcium. See sources and uses of each vitamin with this chart.

The FDA does not approve dietary supplements before they go to market

The US Food and Drug Administration does not regulate products including vitamins, probiotics, and herbal mixes as drugs due to the Dietary Supplement Health and Education Act of 1994, which amended the Federal Food, Drug, and Cosmetic Act. Because dietary supplements are regulated as a subcategory of foods, inspectors do not assess whether dietary supplements work as advertised before sale.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Vitamin B1 is linked to gut motility—helping fight constipation—in 2026 research

A study published in early 2026 found a link between vitamin B1 and the successful movement of food through your GI tract, known as gut motility. The work incorporated genetic and survey data about poop frequency to identify genes associated with gut motility and then separately linked poop frequency data with how much vitamin B1 people ingested, theorizing that the vitamin supports the production of acetylcholine, a neurotransmitter that stimulates GI system contractions.

Listen to how the 1902 'poison squad' experiments changed food safety in America

As part of government research, a group of young men were paid to eat standard American food—replete with food additives like borax and formaldehyde—which revealed the dangers of unregulated food. The work was led by the first FDA commissioner, Harvey Wiley, who helped end the "century of the great stomachache."

In 1933, the influenza virus was first identified through “ferret flu” experiments

In 1933, British researchers dripped filtered nasal fluids from a sick colleague into ferrets, which quickly developed “ferret flu.” This experiment proved influenza was viral, not bacterial, and established the basis for modern flu vaccines.

Fat is proposed as a candidate sixth basic taste

Oleogustus is Latin for "a taste for fat," and researchers proposed in 2015 that it should be accepted as the sixth basic taste. This article teases apart exactly what it would take to officially be considered the sixth taste and why researchers think the fat taste may be a strong candidate.

Yes, you can take too many vitamins and they can make you sick

Too much of vitamins A, D, E, and K (which are fat-soluble) can build up in the body and cause serious health problems, including liver damage, kidney stones, and blood clotting irregularities. Excess iron and calcium can also make it harder for the body to absorb other needed nutrients.

Western babies often are missing a key gut microbe common elsewhere

Studies show infants in Europe and North America often lack Bifidobacterium infantis, a microbe widespread in babies in Africa and South Asia that helps digest breast milk and train the immune system. Researchers link the gap to antibiotics, formula use, and sanitized spaces.

Lack of Vitamin D seems to be one major factor fueling MS risk

Researchers believe that a combination of factors can elevate MS risk, including a lack of vitamin D exposure in different locales, genetic history, cigarette smoke exposure, and Epstein-Barr virus infection.

Ketchup, 101

Ketchup is a tomato-based condiment mixed with vinegar, salt, and spices. The word likely originates from Southeast Asia, where it was used for a common fish brine sauce in the 18th century. For a brief period in the early 19th century, ketchup was viewed and marketed as a medicine. Henry John Heinz formulated a standard recipe in the late 1800s.

Alkaptonuria was the first identified genetic disorder

In 1902, a rare recessive mutation was determined to cause alkaptonuria—a disease that induces dark pigmentation of connective tissue. The responsible gene was not isolated until the 1990s.

The ubiquitous 1990s “Got Milk?” ad campaign was intended to fix milk’s dwindling popularity in the late 20th century

Despite its success in spreading the word about milk, the sales numbers weren’t quite as impressive. This Mental Floss article details the marketing efforts themselves, as well as how milk lobbyists didn’t necessarily succeed despite their revolutionary ads.

Understanding insulin

Scientists Daniel and Kelly talk with researcher Dr. Katrine Whiteson about diabetes, the history of insulin production, and Dr. Lydia Villa-Komaroff—an essential member of the team who discovered that bacteria could be induced to produce insulin. Listen to discover interesting facts about the life-saving medicine and how it works in the human body.

Can humans delay or reverse old age?

We're not sure yet. Researchers at the University of California San Francisco are studying why some conditions and behaviors, such as low-oxygen environments and exercise, benefit the aging process, hoping to reveal potential health applications. Some of this research focuses on klotho, a naturally occurring age-regulating hormone named after the Greek Fate Clotho. Animal studies on klotho brain injections found subjects had improved memory recall and age-related degeneration resistance.

JJ Schildkraut theorized depression is linked to brain chemical imbalances—in 1965

Schildkraut was one of the first to put forward this idea, which stemmed from lab animal research. A decade later, researchers published the first landmark paper on fluoxetine—better known by trade name Prozac—which increases serotonin levels in the brain.

Bacteria helped scientists realize that DNA was the hereditary molecule, not proteins

Until the mid-1900s, most scientists believed genes were made of proteins, which were known to act as enzymes, hormones, and other chemicals that mediated an organism's traits. The Avery-MacLeod-McCarty and that benign bacteria could be made lethal, where the inherited factor that caused bacterial transformation contained DNA.

The American Research and Development Corporation is considered the first modern VC firm

Best known for investing in companies that wanted to utilize some of the technology developed during World War II, the ARDC’s cofounders all held prestigious positions at places like MIT and the Federal Reserve Bank of Boston.

A history of treating frostbite

Amid Napoleon's invasion of bitterly cold Russia, soldiers succumbed to frostbite by the thousands. Nineteenth century doctors recommended walking and rubbing snow around the affected area. Fast forward to recent years, and the FDA has approved its first ever drug to treat frostbite. Listen to this podcast to learn the history of this wintry affliction.

The story of the first British royal visit to the US in 1939

Amid pre-World War II diplomatic efforts in June 1939, King George VI and Queen Elizabeth I (not her better-known daughter, Elizabeth II) became the first reigning British monarchs to visit the US—163 years after the colonies declared independence from Great Britain. The five-day meeting began with two formal days in Washington, DC, before concluding at FDR's estate in Hyde Park, where the monarchs reportedly enjoyed hot dogs for the first time.

What is a calorie?

Today it may go without thinking that we measure food by calories...but where did this come from and what does it mean? A kilo-calorie (or, as we call it, simply "calorie") is the amount of heat energy needed to raise the temperature of one...

The discovery of nuclear fission was facilitated by the discovery of the neutron

The discovery of the neutron provided scientists with a particle that could penetrate the nucleus and advance atomic physics. Otto Hahn was the sole Nobel recipient for the discovery of fission, despite collaborating with Lise Meitner and Fritz Strassmann.

Gatorade was first designed for college football players in Florida heat

To help replenish crucial chemicals football players were losing fast to their profuse sweat in southern heat, researchers at the University of Florida developed a drink blended with salts and sugars that were easy to absorb. The drink, Gatorade, took its name from the school's mascot.

A brief history of human blood groups

The blood group that determines whether you have type A, B, AB, or O blood was discovered near the turn of the 20th century. This short academic article dives into three main theories about the evolution and emergence of blood groups, the exact nature of which remains unclear.

Unlike fruits, the category of 'vegetables' is a culinary term, not a scientific one

Within botany, fruits are defined as the ripened ovaries of flowering plants, and include apples, grapes, tomatoes, avocados, green beans, peppers, and almonds. In the kitchen, "vegetables" is an umbrella term that encompasses many fruits and other parts of plants, such as leaves (lettuce, kale) and roots (carrots, beets).

Poison ivy was sent to Europe in the 1600s as an exotic, ornamental oddity, where it was purposefully grown in the English royal gardens at Kew, the Faculty of Medicine in Paris, and a few other locations.

The history of many kitchen appliances involves unexpected discoveries and applications, including wartime radar turned hamster defroster and replacing an 'ice king' with heat-stealing boxes.

Ebola is a filovirus, meaning it resembles a thread under a microscope, though it sometimes twists and can resemble a bowl of spaghetti.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

How fusion—which releases energy when two lighter atoms combine to form a heavier atom—differs from fission

Walt Disney's early film 'Alice's Wonderland' was a groundbreaking innovation in the silent film era

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Venture capital is a form of funding provided to early-stage companies with high growth potential, typically in exchange for an equity (or ownership) stake

Many legends about George Washington, including his supposed wooden teeth and the story of cutting down the cherry tree, lack evidence.

In 2026, Finland was named the world's happiest country for the ninth consecutive year based on its wealth, social safety network, and high life expectancy, among other factors.

The Mona Lisa's celebrity status and repeated restorations have obscured what made the painting so revolutionary for its time

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

A researcher recently discovered an interview from 1967 between groundbreaking journalist Joan Didion and the Grateful Dead, years before the band became an institution.

Despite being favored by 87% of Americans, Congress does not have term limits.

Most of the observable universe's volume consists of voids and supervoids—enormous regions of space with little to no galaxies, stars, or light.

The Beatles' US label rejected the band's first two singles, 'Please Please Me' and 'From Me to You,' with one executive calling the band 'dead in the water.'

The term 'algorithm' originated from the Latinized name of al-Khwārizmī, a 9th-century mathematician whose works introduced Arabic numerals and the decimal-based numeral system to Europe and whose treatise 'Al-Jabr' gave algebra its name.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

The US first hosted the World Cup in 1994, a tournament that lives in soccer infamy for its poor planning and the murder of Colombian player Andres Escobar, who'd accidentally scored on his own net.

The rivalry between Alexander Hamilton and Thomas Jefferson centered on federalism—the question of how much power the federal government should hold relative to the states.