The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

Research suggests the brain maintains connections to lost limbs

Decades-old research suggested brain reorganization after amputations, but brain scans show unchanged limb representations. Phantom limb pain may result from such unchanged brain maps, which may enhance prosthetic limb control in brain-computer interface technology.

The oldest medical report of a near-death experience dates to around 1740

In 2014, Dr. Philippe Charlier, a medical doctor and archeologist, found a French medical book from 1740 that described the near-death experience of a pharmacist. Using the Greyson Scale, Charlier found that the incident would have rated at least 12/32, more than high enough to scientifically classify as an NDE by today’s standards.

The virus was officially described for the first time in 1789

Michael Underwood, an English physician and surgeon, was the first to describe the disorder, noting it caused disability in the lower extremities in children. Large-scale outbreaks of the disease were not observed until the late 19th century.

The word 'vampire' appeared in the English-speaking world in the 1730s

However, earlier mentions of creatures with similar characteristics existed throughout Medieval Europe. For example, people often spoke of revenants—restless dead creatures who tormented the living. Historians believe these stories grew in popularity in part because of influence from the Catholic Church, which was emphasizing the idea of purgatory. These older revenant stories eventually influenced modern vampire folklore.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

The medical profession has a dark history of 'body snatching' for education

This term originally referred to secretly removing corpses from graves for sale—usually to medical schools where they were used for education. The practice dates back at least to the 1300s but still—much more rarely—persists today.

19th-century Americans used technology to try to prove the existence of ghosts

In the 19th century, following technological advancements like the telegraph, phonograph, and others, efforts were made to capture proof of ghosts. These technologies seemed supernatural in their own right and emerged at the same time Spiritualism took off in the US, resulting in new approaches to connecting with the dead.

Everything you know about Phineas Gage is wrong

A stray spark sent a 3.5-foot-long, 1.25-inch thick iron rod through the brain of foreman Phineas Gage in 1848, creating a scientific case that has attracted onlookers for nearly two centuries. His life reportedly soon spiraled out of control, with his behavior tending toward selfishness and chaos. Evidence of these changes is far less common, with Gage's story bloated by fabrication, scientific prejudice, and artistic license.

Surgery before the dawn of anesthesia

The arc toward anesthetics was painfully slow, with early pain mitigation offerings ranging from analgesics—drugs that dim pain but don't block it—and numbing surgical sites with cold water to gassing patients with carbon dioxide or bashing or bleeding them unconscious. Such treatments and the torturous surgery they preceded led many to avoid even life-saving procedures, and those who survived often kept silent about the trauma.

With no textbooks or antibiotics, this WWI surgeon pioneered facial reconstruction

New Zealand surgeon Dr. Harold Gillies made extraordinary advances in the field of reconstructive surgery during World War I and after. This 36-minute NPR podcast interviews historian Lindsey Fitzharris, author of Gillie's biography, The Facemaker, charting how the good doctor reconstructed the faces of numerous soldiers in an age before antibiotics and plastic surgery as we know it today.

Synesthesia: when sensation in one sense triggers an unrelated sense in the brain

The first reported clinical case of synesthesia dates back to the early 1800s, though the perceptual phenomenon may be much older than surviving records imply. This article by researcher Richard Cytowic details the scientific history of synesthesia, a neurological trait that causes some senses to overlap, giving color to numbers and flavors to names.

The peer support movement may date back to 18th century France

At the Bicêtre Hospital, an asylum near Paris, Jean-Baptiste Pussin (who had previously been a patient but later led the hospital administration) tried to hire as many staff as possible from among recovered patients. Chief physician Philippe Pinel found these individuals to be kinder than other staff and "averse from active cruelty" which was common at the time. This approach allowed the facility to move away from shackling patients and other violent methods.

See haunting images of the plaster casts of Pompeii’s victims

The plaster casts preserve victims’ final moments in striking detail—from their poses to the expressions frozen on their faces. This piece explains how 19th-century archaeologist Giuseppe Fiorelli devised the method long after the bodies had decomposed.

Peptide research dates back to the late 1800s

Peptide science dates back to the late 1800s with some early peptide synthesis work, but peptides took off in the medical sphere after surgeon Frederick Banting and his colleague's isolation of insulin from dog pancreases in 1921.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Pilates was invented by an acrobatic WWI prisoner of war

As the Great War raged on, and as months gave way to years, the imprisoned Joseph Pilates explored a question that he had pondered since childhood: Could he reimagine the capabilities of the human body through an anatomically based method of training, taking inspiration from scientific treatises, the carefree movement of children, and the dexterous ease of cats? Read this article to learn about the birth and legacy of Pilates.

Why Men's Legs Were Everything

From codpieces to cotton hose, here's the surprisingly loaded history of men's legs, and why 18th-century Europe couldn't stop staring at them.

The art of 'undiscovering' phantom islands

Centuries of maps include islands and isles that appear to only exist on atlases. This article explores the discovery and "undiscovery" of such landscapes, which still persist despite modern technology. As recently as 2012, Google Maps showed an...

Salvador Dalí believed he was his own dead brother

Dalí's parents found the miracle of his birth nine months after his brother died to be profound, telling him he was his brother's reincarnation. Dalí carried this belief into his adult life and often cited its deep influence on him, including his preoccupation with death and mortality.

Salvador Dalí believed he was his own dead brother, who had died nine months before he was born

Modern swordsmen still are trying to figure out how medieval knights fought

There's no line of succession for the secrets to fighting like a medieval European knight. All the primary sources of information on the art are either dead or trapped in vague manuscripts. But that doesn't mean people aren't trying to piece the martial art back together. This article explores one group's attempt to revive the world of historical European martial arts.

Revolutionary War reenactments have taken place for centuries

The first known reenactment of the war occurred in 1778, while the war was still ongoing. A journal entry from a lieutenant colonel in the Continental Army remarked that soldiers had commemorated a “Glorious victory obtained over the British” at Saratoga with “a Grand sham fight.”

Charles and Ray Eames designed military leg splints in WWII

The married couple is most famous for their sleek, modern office furniture, but they also designed leg splints for injured soldiers in World War II.

Fantasy sports began in the 1860s

“Sebring Parlor Base Ball,” a tabletop board game in which players flicked a coin as if they were hitters is believed to be the first game that allowed players to imagine themselves as athletes without actually taking part in physical activities.

The first 3D printing patent was filed in 1967

Wyn Swainson, an English literature graduate student, filed a patent in Denmark for a system that scans an object and uses the scanning data to rebuild it using lasers that harden light-sensitive plastic. However, he never developed a working prototype. The idea originated from wanting to produce recreations of sculptures.

Sleep paralysis occurs when the body fails to 'unfreeze' in sync with waking

When the body falls into a deep enough phase of sleep, it paralyzes certain parts of itself so the brain can't force it to physically act out dreams. This well-known but little-understood phenomenon happens when the brain awakens early and typically results in haunting hallucinations and reports of supernatural terrors.

The origin of cyborgs

The term "cyborg" was coined in a 1960 academic paper discussing what alterations humans would need to undergo to survive in extraterrestrial environments, a venture far "more logical than providing an earthly environment" in space. According to authors Manfred E. Clynes and Nathan S. Kline, Cyborgs with a capital C have incorporated exogenous components that extend their ability to adapt to new environments. Read the paper here.

Firework or sparkler burns can have large effects on our hands' range of motion

Dr. Erin Miller, a hand surgeon at Harborview Medical Center in Seattle, describes the range of injuries she's seen from firework injuries in this 2020 video. The damage includes loss of hands, fingers, and tips of fingers. Miller describes how in a recent year she was on-call during the week of the Fourth, and in just five days she saw 30 cases and had to amputate 42 fingers because of fireworks injuries.

The first horror movie is believed to be George Méliès' 1986 short 'The Haunted Castle,' which pioneered the use of special effects

The first robot in literature may have been a 'mechanical man' in 1907's 'Ozma of Oz,' a book in L Frank Baum's 'Wizard of Oz' series.

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

Learn more about the history of fireworks, which dates back to an accidental invention during an alchemist's quest for information about immortality.

Many legends about George Washington, including his supposed wooden teeth and the story of cutting down the cherry tree, lack evidence.

In 1915, workers recovered a submarine-like vessel from the Chicago River, prompting fears of German espionage

About 12.5% of US adults experience a phobia in their lifetime, a diagnosis that hinges on the intense fear interfering with daily life and persisting for at least six months.

For centuries, it was common to sleep in two shifts: a few hours at the beginning of the night, and a longer period beginning around midnight

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

Cultural norms about how to handle the bodies of loved ones in communities in West Africa have hampered Ebola responses.

Poison ivy was sent to Europe in the 1600s as an exotic, ornamental oddity, where it was purposefully grown in the English royal gardens at Kew, the Faculty of Medicine in Paris, and a few other locations.

The Mona Lisa's celebrity status and repeated restorations have obscured what made the painting so revolutionary for its time

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

In 2025, four executives from large tech companies were given positions in the US Army Reserves—including Palantir Chief Technology Officer Shyam Sankar, which reinforced Palantir's ties with the US military and its role as a leading defense partner.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

American short story writer Flannery O'Connor raised 40 peacocks, which became potent symbols for her fiction's elegant violence

Trace how the Bill of Rights, inspired by centuries of political theory, took shape between 1774 and 1789.

Mark Twain spent decades feuding with the US Postal Service, convinced its costs and regulations were bureaucratic overreach.

The word 'jazz' evolved from 'jasm,' 19th-century American slang for 'energy'