Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

Watch an expert's take on the rare disease hantavirus—and why it's not of great concern to the general population

This rare zoonotic disease, transmitted to humans primarily through infected rodent droppings, urine, or saliva, is rarely spread between people. The disease was of particular concern in spring 2026, when an outbreak occurred on a 150-person cruise ship, prompting a flurry of action, including contact tracing for passengers in their home countries. The disease can be fatal. But early care—primarily oxygen support—can help patients survive.

Human-to-human transmission of hantavirus remains extremely rare, so the 2026 hantavirus cruise ship outbreak doesn't mean we're facing a COVID-style pandemic risk.

See the evolution of Ebola vaccine and treatment development.

See the evolution of Ebola vaccine and treatment development

The recently approved vaccine and treatments against Ebola are the result of many years of investments and have reshaped how the world addresses Ebola outbreaks. Four drugs were tested in the midst of the 2014 outbreak. Two proved to be so effective the clinical trial ended early. The vaccine proved effective during the 2018-2020 outbreak in the DRC.

Using mosquitoes to vaccinate bats could curb the spread of deadly diseases

Researchers in China tested a transmissible rabies vaccine in the lab by feeding mosquitoes blood containing the vaccine and observing what happened to bats when they were either bitten by the mosquitoes or fed on them. The bats developed antibodies against rabies and survived subsequent rabies infection. (Some users may encounter a paywall.)

Two Lyme disease vaccines were in development in 2026

As of early 2026, there was no vaccine for Lyme disease available. One candidate vaccine, VLA15, was in later-stage clinical trials. Another designed to provide seasonal protection was licensed to a pharmaceutical company in 2025, and was planned for human clinical trials.

Marburg virus, related to Ebola, is also extremely deadly, and has no available vaccine.

A major US-designed polio vaccine was first tested in the Soviet Union

Albert Sabin's live attenuated virus vaccine—requiring two drops in the mouth—didn't garner political support in the US, so it was tested in the Soviet Union in the late 1950s.

Horses have four licensed West Nile vaccines—but humans have none

A major hurdle for West Nile vaccine development is the lack of a market for it since so many people are symptomatic for the infections. Still, a growing number of infections, including a 40% spike in 2025, may change that calculation.

US federal researchers are blocked from putting certain human cells in animals

In 2015, US policymakers put a halt to any government-funded work that would insert human stem cells into animals. The reasoning was that human cells might spread through the animal's body and perhaps to its brain, blurring the line between humans and nonhumans. The ban remains in place today even as gene-edited pig parts are being placed in humans.

This scientist treated her own cancer

Virologist Beata Halassy treated her own breast cancer by injecting the tumor with lab-grown viruses. Though this self-treatment worked, it has not been approved for widespread use. Read to learn more about her fascinating experience, and how it has led to conversations about safety and ethics.

What are universal vaccines?

As viruses mutate and develop, vaccines have to adapt, leading to regular recommended injections like flu shots. Researchers are working to develop universal vaccines that aim to protect against multiple virus variants if not entire virus families. These vaccines work by creating broadly neutralizing antibodies (bnAbs) that target aspects of viruses that don't typically mutate and are integral to the virus' survival.

The American Veterinary Medical Association advocates for vaccinations for pets to extend their lives

The American Animal Hospital Association provides guidelines, while many states legally require certain vaccines, such as rabies. Vaccinating healthy pets—even indoor-only pets—prevents outbreaks and protects other vulnerable animals, and adverse effects, such as allergic reactions and injection-site irritation, are rare. (Some readers may experience a paywall.)

In 1933, the influenza virus was first identified through “ferret flu” experiments

In 1933, British researchers dripped filtered nasal fluids from a sick colleague into ferrets, which quickly developed “ferret flu.” This experiment proved influenza was viral, not bacterial, and established the basis for modern flu vaccines.

How mRNA vaccines work

mRNA COVID-19 vaccines were developed faster than any vaccine ever made. Even more enticing, the underlying technology may unlock preventive treatments for a wide-range of diseases.

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

Hookworm infection, though risky, may help fight certain health conditions

Early clinical trial research suggests that the parasites trigger the production of specific proteins that quiet our immune systems. This keeps the parasites from being killed, but it also quiets the inflammatory response that underpins allergies, type 2 diabetes, celiac disease, and other autoimmune conditions. Researchers still caution that infection with too many hookworms can cause serious medical complications and that this is not a standardized or approved medical treatment.

Lyme disease-causing bacteria predate any suspected biological weapons testing

Borrelia bacteria existed long before any US biological weapons program—or human presence in North America. One study comparing genomes of the bacteria behind Lyme disease collected samples of the bacteria over three decades and calculated that the bacterium has been in North America longer than humans, at least 60,000 years. Other work found related bacteria preserved in amber from millions of years ago.

Researchers are investigating if nanoparticle treatments could combat allergies

In rodent work, Northwestern University’s Evan Scott (now at the University of Virginia) and his colleagues have been trying to attack allergies with specially designed nanoparticles—miniscule lab-made objects that can penetrate cells. They stud the nanoparticles with a tiny bit of the allergen specific to the allergy (i.e. cashew protein for cashew allergy) and antibodies that shut down allergic response processes.

Environmental conditions, shifting immunity, and viral strain could help explain 2025 spike

The surge in HFMD in the summer and early fall of 2025 in the mid-Atlantic could be the result of a confluence of factors, including a more virulent strain of disease-causing virus, good environmental conditions for the virus to spread—hot, humd—and a potential immunity gap among kids due to milder HFMD outbreaks the previous year.

Veterans reported single dose of ibogaine improved TBI, PTSD, anxiety, and depression

Research published in 2024 on the Central African plant-derived drug included 30 male combat vets who received ibogaine treatment in Mexico. It reported significant reductions in multiple mental health conditions and no serious side effects. Other work, however, has shown the substance can cause fatal cardiac arrhythmias, killing at least 19 people between 1990 and 2008. (Some users may encounter a paywall.)

The Armamentarium is a set of new gene therapy tools to fight brain diseases

Research from 29 universities and institutions across North America has resulted in the development of 1,000 tools that provide large-scale, cell-type specific targeting for the first time. These tools may be used to alter the activity of brain cells to address some neurological diseases and sleep disorders.

Read about Palantir's role in the COVID-19 vaccine rollout

Palantir developed Tiberius, a software service that supported the public-private partnership spearheaded by then-President Trump to roll out COVID-19 vaccines. The software tracked state-by-state vaccine allocations, as well as COVID-related hospitalizations.

Early peptide research focused on isolating the substances from animal tissue

In the first half of the 20th century, peptides including insulin and adrenocorticotropic hormone were isolated from animals to provide life-saving medicines. ACTH was isolated from the pituitary glands of cows and pigs and insulin was isolated from the pancreas of dogs and cows.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

A fake vaccine campaign was used to locate Osama bin Laden, fueling vaccine distrust

As part of the intelligence operation to find bin Laden in Pakistan, the US Central Intelligence Agency recruited a Pakistani doctor who ran a fake hepatitis B vaccine campaign and obtained DNA samples from bin Laden. News of this fake campaign fueled further distrust of healthcare workers, attacks on them, and stymied efforts to vaccinate against polio in the region.

People can—and have—contracted leprosy from armadillos

A 2011 study linked multiple human cases to the handling of armadillos or the consumption of their meat. The research couldn't document direct transmission, but did find that the animals and humans shared the same exact strain of the disease.

Harvard drowned rats for this?

Harvard's 1950s rat study was ethically questionable, but scientifically profound. One rescue attempt made rats swim 40x longer. The finding: hope isn't poetic, it's biological.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

In 2025, four executives from large tech companies were given positions in the US Army Reserves—including Palantir Chief Technology Officer Shyam Sankar, which reinforced Palantir's ties with the US military and its role as a leading defense partner.

The food processing techniques developed for World War II, later repurposed for consumers

Research projects funded or sponsored by the military led to the development of active dry yeast to make bread easier to bake and an improved version of dehydrated cheese, which would be used in powdered cheese snacks. Freeze-drying, which had been used to ease the transport of blood plasma to battlefields, where it would be reconstituted with water, was later used on fruit for cereals.

Early testing of the US Army's mixed reality headsets made soldiers perform worse

Soldiers involved in testing the Integrated Visual Augmentation System reported headaches, nausea, limited peripheral vision, and concerns about security due to the display backlighting, which could be viewed from hundreds of meters away. The difficulties led the Department of Defense to transfer the program's contract from Microsoft to Anduril Industries.

Before humans, the Soviet Union and the United States sent animals—including apes, dogs, and cats—to space during the Space Race.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Venture capital is a form of funding provided to early-stage companies with high growth potential, typically in exchange for an equity (or ownership) stake

Poison ivy will likely become both larger and more resilient due to climate change.

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

11 people died from firework injuries in the US in 2024.

While the first exchange-traded fund (a 'basket' of different assets that can be bought and sold on a stock exchange) in the US only launched in 1993, the global ETF market has grown to more than $10T in the short time since.

NBA superstar Victor Wembanyama spent the 2025 summer training with monks in central China to enhance his body and mind.

In 2019, a laptop loaded with six of the worst malware in history and described as 'an exhibit of historical weaponry' sold for $1.3M.

The United States has had a tumultuous relationship with Cuba since its 1959 revolution, highlighted by a nuclear crisis and a decades-long trade embargo.

The tragic Pulitzer Prize-winning image 'The Vulture and the Little Girl' (1993) generated controversy, raised concerns about ethics in photography, and eventually led to the photographer's death.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

A 2019 Facebook event called on attendees to "Storm Area 51, They Can't Stop All of Us," resulting in countless memes, the creation of a music festival, and eventually the arrests of those who did try to approach the area.

The USPS spent $3.97B in 2024, accounting for .058% of the federal budget.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

Before the current East Wing ballroom project, only two White House renovations in the past 100 years cost more than $10M.