As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

The applications and industrial uses of graphene, the single-atom-thick material

Shortly after its discovery in 2004, the strength, flexibility, optical properties, and conductivity of this thin layer of carbon atoms earned it the designation of a "wonder material," but breakthroughs in its use have taken decades of research. As of 2026, graphene-enhanced electronic sensors, optical microchips, concrete, and supercapacitors are available, though scale production challenges remain.

Nature simultaneously published three papers on DNA—only the first made history

Papers by Watson and Crick, Wilkins, and Franklin were fast-tracked without peer review, and their order was arranged between lab heads and editors. Franklin's appeared last, making her paper read as though supporting Watson and Crick—because they'd already incorporated her data before it was published.

Browse a list of the most important scientific breakthroughs from each state

Although scientific discoveries involve experimentation, analysis, and collaborations among many individuals across a variety of locations, some observations, advancements, and breakthroughs have their origins in facilities within the US. These include the polio vaccine in Pennsylvania, the breathalyzer in Indiana, the observation of Pluto in Arizona, and the invention of nylon and Teflon in Delaware. (Some readers may experience a paywall.)

Explore a list of Nobel Prize winners supported by National Science Foundation grants

As of 2025, 274 Nobel laureates have received funding from the NSF at some point during their careers, including 49 in physiology or medicine, 82 in physics, and 70 in chemistry. The 73 NSF-funded laureates in economics include every prize winner since 1997.

How PageRank—Google's search algorithm—mimics academic citation analysis

Just as research papers carry more weight if they are cited more often and cite major papers to reach their conclusion, Google's PageRank identifies search relevance based on the number and quality of links pointing to a page.

During his 'miraculous year,' Einstein published four groundbreaking papers

The 1905 "annus mirabilis" papers explained the photoelectric effect, Brownian motion, the absolutism of the speed of light, and mass-energy equivalence, revolutionizing scientists' understandings of space, time, mass, and energy. For the discovery of the photoelectric effect, Einstein won the 1921 Nobel Prize in Physics.

Using deep learning to analyze tumors

The explosive growth of life sciences data is driving artificial intelligence methods to gain traction in biology and medicine — including cancer research.

How 3D printing inside cells paves the way for microscopic machines

In 2026, scientists in Slovenia developed a method to 3D print a small elephant, several microscopic geometric objects, and barcodes for cell labeling within living human cells, which continued to grow and divide thereafter. The experiment opens the door to fabricating devices within cells to study and manipulate cellular functions.

Peptide research dates back to the late 1800s

Peptide science dates back to the late 1800s with some early peptide synthesis work, but peptides took off in the medical sphere after surgeon Frederick Banting and his colleague's isolation of insulin from dog pancreases in 1921.

Learn why modern scientific patterns have been described as theories rather than laws

After confirming that the accuracy of some laws of physics is limited to certain domains, science became more hesitant to categorize identified mathematical relationships, such as quantum mechanics, as unchanging laws. Instead, these recent, complex frameworks are designated as theories to acknowledge that they are conditional and may be part of a larger, more complete future framework.

Several birthstones play key roles across modern technologies

Diamonds are used in drills and quantum computing, while peridot and zircon help in steelmaking and carbon capture. Rubies, sapphires, and alexandrite enable several varieties of lasers found in medicine and advanced optics. Garnets are found in water filtration systems and radiation detectors. Sapphires are used as substrates in semiconductors.

Multiple new research paths may lead to slowing (or even reversing) aging

Aging has always been inevitable, but fasting, epigenetic reprogramming, and parabiosis seem to help people stay young. By studying centenarians, memory, and even the humble roundworm, scientists are looking for the genetic basis to live not just a long life, but a healthy one.

As of 2025, CERN is the world's largest particle physics laboratory

Founded in 1954, the European Organization for Nuclear Research's laboratory is located near Geneva, Switzerland, and more than 10,000 scientists from more than 100 countries visit its facilities each year. Its largest tool is the Large Hadron Collider, a 27-kilometer-long tunnel that accelerates protons to near the speed of light.

A top Alzheimer's researcher was accused of faking results

In 2021, an investigation revealed photo manipulation in images from a seminal 2006 paper by researcher Sylvain Lesné on the role of amyloid plaques in progressive Alzheimer's disease. The revelation rocked the field, leaving many wondering whether they had tried to build on fabricated results. (Some users may experience a paywall.)

Search this citation-heavy database of nutrition and supplement research

Explore a reference site that aggregates and summarizes peer-reviewed studies on hundreds of supplements and dietary interventions. It is ad-free and funded by subscriptions, making it a health resource without a financial stake in what you buy.

How MIT researchers have used genetic mutations to improve photosynthesis efficiency

Recognizing that RuBisCO—a protein that binds carbon dioxide to other compounds to produce the building blocks of organic molecules—often mistakenly binds oxygen, scientists performed directed evolution experiments to modify the geometry of a bacterial version of the protein to cause it to preferentially interact with carbon dioxide over oxygen.

Moore's Law came from observing exponential computing growth in the 1960s

In 1965, Gordon Moore, cofounder of Intel Corporation, observed a four-year trend of constant growth rate in computing power. Hypothesizing the trend would continue, his observation became the benchmark that the computing industry has worked to maintain for 60 years.

The 100 most significant sports moments between 2000 and 2025

This list ranks the 100 most significant sports moments of the first 25 years of the 21st century. The editors compiled the collection based on a list of factors, including the "collective joy" factor, whether it made you curse in disbelief, and how much it transcended the sport and entered the broader culture. The top moment: The improbable "helmet catch" during the Super Bowl in 2008.

As of February 2025, there are more than 150 clinical trials using CRISPR technology

The clinical trials are designed to determine whether experimental CRISPR-related therapies are safe and effective. The majority of trials involve treatments for blood disorders, including beta thalassemia.

The five most common chemicals found in modern food

Most modern processed foods rely on a number of preservatives to stay fresh from production to our plates. The most common include citric acid (preservative and flavor), sodium benzoate (preservative), xanthan gum (thickening and stabilizing), carrageenan (thickening), and red dyes 3 and 4 (for color).

Review Congress's 2025 report on the history of US critical mineral policy

For decades, supply chains for critical minerals have grown increasingly vulnerable due to reliance on imports. In 2022, the US Geological Survey expanded the list of critical minerals to 50 to better reflect growing industrial needs, exacerbating this vulnerability.

Traffic flow can be improved through research into card shuffling

Card-shuffling mathematics has been applied to solving problems in biology to estimate the evolutionary distance between organisms and in computer science to determine the optimal distribution of files and folders in databases.

The 2019 Nobel Prize in Chemistry was awarded for lithium-ion battery development

Stanley Whittingham developed the first functional lithium battery in the early 1970s, while John Goodenough doubled its electrical potential in 1980 by replacing the cathode, thereby enhancing its commercial viability. Five years later, Akira Yoshino developed an anode using carbon material, reducing the risk of flammability.

See February 2026's best science images, including raining iguanas.

What sleep loss does to the brain

Proteins in the brain perform various critical functions, such as helping neurotransmitters function or enabling electrical activity in the organ. These proteins must fold in specific ways to perform their duties, similar to paper airplanes. Sleep deprivation contributes to the gathering of misfolded proteins that aren't shaped correctly for their roles and so accumulate in undesired spaces, such as in the gaps between neurons.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Watch how algorithms can be designed to train themselves and self-improve without human input, to the point where the optimized code is too complex for programmers to understand.

Electrical grids worldwide must double their power delivery capacity by 2050 to meet surging demand from AI and electric vehicles.

Browse a detailed visual analysis of over 200,000 similes—comparisons that often use 'like' or 'as'—from popular fiction to see how frequently writers the same idiomatic expressions.

The American Society of Civil Engineers' infrastructure report card gave the US a C in 2025, its highest grade since the project launched in 1998.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

SpaceX's S-1 or 'prospectus' revealed many previously unknown details about the company, including its unprofitability despite doing $18.7B in revenue in 2025, exactly how many voting shares Elon Musk will have in the company (roughly 85%), and more.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

In 2026, Finland was named the world's happiest country for the ninth consecutive year based on its wealth, social safety network, and high life expectancy, among other factors.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

A century of Billboard issues documenting the evolution of popular music.

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

Sony set the standard for cylinder-shaped batteries when it repurposed manufacturing equipment used to make rolls of magnetic recording tape.

Ebola is a filovirus, meaning it resembles a thread under a microscope, though it sometimes twists and can resemble a bowl of spaghetti.

See how fireworks are made and learn how metals like magnesium and copper are responsible for different colors.

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

Neutron stars, the remains of some massive stars after they explode in a supernova, are the densest directly observable objects in the universe.

SpongeBob exemplifies Aristotle's philosophy for living well because he understands that happiness doesn't come from external factors like money, recognition, or power.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.