A top Alzheimer's researcher was accused of faking results

Is conventional wisdom about amyloid plaques wrong?

Neurobiologist Karl Herrup makes the case for reevaluating current research paradigms and embracing a more comprehensive understanding of Alzheimer's disease. He highlights years of failed clinical trials of drugs reducing amyloid plaques in treating Alzheimer's, the establishment of that theory based on a single patient, and more.

The scandal that rocked stem cell research

In 2014, a Japanese research group published a paper suggesting ordinary cells could be reverted to pluripotent stem cells by subjecting them to external stressors. The results generated interest but could never be replicated. The lead researcher was accused of fraud, and the group’s supervisor committed suicide.

There are two FDA-approved blood tests that may detect early Alzheimer's disease

Yet the tests are only recommended for those who have symptoms of dementia, and are not definitive on their own. False positives are a concern with these new tests, which detect biomarkers that may indicate the presence of brain proteins linked to the disease. This podcast explores the state of research on the disease and concerns about regulators taking jobs at pharmaceutical and biotech companies, which may influence their approach to approvals. It also dives into an investigation about the data underpinning one experimental Alzheimer's drug.

Researchers are exploring neural links between Alzheimer's and autism

Recent DNA sequencing and molecular biology studies suggest that similarities in genes, neural circuitry and patterns of disease warrant further exploration to potentially better understand both conditions and how to treat them. (Some users may encounter a paywall.)

Researchers use the brain's ability to edit memories to explore memory deletion

Scientists have successfully implanted false memories in mice after studying how the editing process works in the brain. Beyond potentially deleting memories in those with PTSD, upcoming research may allow clinicians to forecast the onset of neurodegenerative diseases.

Read the original 1907 paper on the first known Alzheimer's patient

Alzheimer's disease was first identified by Dr. Alois Alzheimer in 1901, following a postmortem brain examination of a patient experiencing memory loss and other symptoms. Alzheimer's original paper was largely lost until 1995, when an English translation was published in a medical journal.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

A pediatric journal ran 138 fictional case studies, and 61 were cited as real stories

The Canadian journal Paediatrics & Child Health issued corrections to 138 case studies published since 2000, acknowledging the cases were entirely fictional—a practice intended to protect patient privacy that was never disclosed to readers. At least 61 of the fabricated reports were cited as fact in other peer-reviewed journals a combined 218 times, including a 2006 Lancet article alleging an infant died from opioid-laced breast milk.

Two festival-goers were hospitalized after receiving peptide injections, raising questions

Investigative journalism shop ProPublica wrote about two people who became extremely ill following antiaging peptide injections. Authorities were examining whether the individuals were sickened by an infection, contamination related to the injections, or an issue with the medication itself, according to documents obtained by the journalists at ProPublica.

Deepfakes use AI to produce manipulated media to mislead viewers

Unlike most content created from large language and diffusion models, deepfakes intentionally misrepresent real people or events with the intent to deceive. As the products of this technology become more realistic, they pose increasing risks to public trust, security, and privacy.

Did a Smithsonian anthropologist steal people's brains?

This comic examines "racial brain collection" of Ales Hrdlicka, the Smithsonian's head of physical anthropology during the early 1900s. Hrdlicka was a white supremacist who sought physical evidence for his theories on anatomical differences between...

Investigation finds 'influencer' dietitians paid to promote sugar, supplements on social media

A joint investigation by The Examiner and The Washington Post found that food, beverage, and supplement corporations and groups have paid registered dietitians on social media to promote content that goes against decades of scientific evidence on...

American medical organizations rescind recognition of diagnosis cited in police custody deaths

American medical organizations have rescinded their recognition of a syndrome whose theory stemmed from discredited research. This article explores the history and implications of "excited delirium syndrome," a medical condition that can reportedly...

True crime fans can derail lives with misguided accusations

In the wake of four stabbing deaths at the University of Idaho in November 2023, online sleuths, without any supporting evidence, were quick to point accusatory fingers at potential perpetrators. Poring over news reports, social media pages, and internet interactions can reveal viable information that can help solve crimes. Such (sometimes monetizable) behavior can also easily give rise to rumors and threats while impeding official investigations.(Some readers may experience a paywall.)

How Alzheimer's disease affected one family as symptoms progressed

News program 60 Minutes interviewed a couple navigating aging and Alzheimer's over a 10-year period to illustrate the effects of the disease on their lives.

Watson's book was described as misleading when detailing Franklin's role in DNA

Despite working together to win the Nobel Prize for their discovery of the structure of DNA, Francis Crick and Maurice Wilkins objected to the publication of James Watson's account of DNA's discovery. Those involved describe how he villainized Rosalind Franklin and downplayed her work.

Some Nobel laureates have expressed beliefs in pseudoscience after winning

Examples of the phenomenon, known as Nobelitis or Nobel disease, include promoting psychic research, harmful practices like eugenics, and seeing talking raccoons. Increased external pressures after a win and a greater spotlight may contribute to developing or exposing these beliefs.

A funeral director lied and claimed he discovered a centuries-old Roman brooch

An amateur metal detectorist knowingly deceived thousands into believing he found an 1,800-year-old horse figurine. He received payment for the artifact to be featured in a museum, but he later admitted he bought the brooch online and planted it.

33 images that became central to huge scandals

A 2024 cheating scandal cast doubt on the industry

In 2024, National Fantasy Football Championship, a fantasy league with big payouts, fired one of its employees for manipulating data. The episode cast doubt on the relatively unregulated industry, despite the league coming down hard on the nefarious worker.

See how faces on magazine covers have changed over time

This piece examined an archive of Time magazine containing 3,389 issues ranging from 1923 to 2014, focusing on 327,322 faces from the archive. Read what the researchers learned.

In 2008, one writer demonstrated the fickle nature of wine reviews

Robin Goldstein submitted a fake restaurant to the well-respected Wine Spectator for a competition. He created a website for the fake Milan-based business, complete with a menu of wines the magazine itself had disparaged. That didn't stop Wine Spectator from naming Goldstein's ruse among that year's winners.

How Big Oil misled the public into believing plastic would be recycled

An NPR and PBS Frontline investigation reveals how the oil and gas industry used the promise of recycling to sell more plastic, even when they knew it would never work on a large scale.

Government watchdog says nursing homes are inappropriately diagnosing schizophrenia

The Department of Health and Human Services Office of Inspector General said in a March 2026 report that nursing homes are incorrectly diagnosing their residents with schizophrenia to mask the facilities' misuse of antipsychotic medications. The drugs, the report states, are being widely used to make staff members' jobs easier and to keep nursing home quality measures high—since antipsychotic use for schizophrenia wouldn't be counted against the facility. (PDF)

See 33 images that became central to huge scandals, including a young Charles and Camilla, Michael Jackson's baby on a hotel balcony, and Hugh Grant's mugshot.

Court documents reveal how Anthropic destroyed millions of books to build its AI models

Anthropic cut the bindings from purchased books and discarded them after scanning to rapidly collect high-quality text at low cost for training Claude. This, despite hiring the former head of partnerships for the Google Books project, which nondestructively scanned millions of books borrowed from libraries before returning them.

Scientists used mass spectrometry to determine the materials in a 1690 painting

Previously used to map the distribution of molecules on biological tissue samples, researchers combined the technique with machine learning to uncover six layers of pigments, binders, and a thin gold leaf layer within *The Marriage of the Virgin*, from a collection in the Metropolitan Museum of Art. The technique may help identify and track artists' material use to learn about pieces of unknown provenance. (Some readers may experience a paywall.)

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

How the most famous Ebola book, The Hot Zone, which sold 3.5 million copies and was translated into 30 languages, got aspects of the disease so wrong.

The Mona Lisa's celebrity status and repeated restorations have obscured what made the painting so revolutionary for its time

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

In 2019, a laptop loaded with six of the worst malware in history and described as 'an exhibit of historical weaponry' sold for $1.3M.

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

A researcher recently discovered an interview from 1967 between groundbreaking journalist Joan Didion and the Grateful Dead, years before the band became an institution.

In 2009, the nation was gripped by the story of a missing young boy who was believed to be floating over Colorado in a homemade balloon, until it was revealed that he was at home the whole time.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

A 2019 Facebook event called on attendees to "Storm Area 51, They Can't Stop All of Us," resulting in countless memes, the creation of a music festival, and eventually the arrests of those who did try to approach the area.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Massive 3D printers have been used to build homes by stacking layers of 'concrete toothpaste,' a fire-resistant material that effectively insulates against outside noise.

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

Massive blooms of microscopic plankton called dinoflagellates produce the neon blue light seen in glowing tides.