A history of treating frostbite

Reduced inflammation from cold plunges lacks scientific support

The cold water triggers immediate cold shock, increasing heart rate and blood pressure, and prolonged exposure can lead to cold-water incapacitation and hypothermia. Plungers are encouraged to enter the water slowly and manage their breathing to reduce the risk of shock. Warm baths post-plunge are discouraged, and exercise is generally better for recovery.

Wind chill speeds up the loss of heat from the body

During cold weather conditions, strong winds against exposed skin can produce a sensation of temperature colder than the surrounding air temperature. The accelerated loss of body heat increases the risk of frostbite and hypothermia, with frostbite able to set in as quickly as five minutes.

Oxford scientists turned Fleming’s mold discovery into medicine

In 1939, a team at Oxford—including Howard Florey, Ernst Chain, and Norman Heatley—revived Fleming’s forgotten discovery. Using makeshift equipment like bedpans and milk churns, they purified enough penicillin to prove it could treat deadly infections.

What is freezing fog?

Freezing fog is a weather condition in which fog containing supercooled water freezes on contact with objects, forming a layer of ice and possibly dangerous driving conditions. Get the breakdown with this explainer.

The history of many kitchen appliances involves unexpected discoveries and applications, including wartime radar turned hamster defroster and replacing an 'ice king' with heat-stealing boxes.

With no textbooks or antibiotics, this WWI surgeon pioneered facial reconstruction

New Zealand surgeon Dr. Harold Gillies made extraordinary advances in the field of reconstructive surgery during World War I and after. This 36-minute NPR podcast interviews historian Lindsey Fitzharris, author of Gillie's biography, The Facemaker, charting how the good doctor reconstructed the faces of numerous soldiers in an age before antibiotics and plastic surgery as we know it today.

During the French Revolution, a botanist's letter asking about "dear Rhus" (poison ivy) was intercepted and led to authorities' suspicions he was conspiring with the Russians

The 1794 incident involved André-Ignace-Joseph Dufresnoy, a French army physician researching the plants' potential medicinal properties. Rhus radicans is a scientific name for the plant, though it's commonly called Toxicodendron radicans.

FDA approved the first ever peanut allergy treatment in January 2020

This new medication, called Palforzia, is designed to stave off severe reactions from accidental peanut exposures with a daily dose that is increased over time under an allergist’s supervision. It’s not a treatment that should be administered during an allergic reaction, however. Epinephrine, usually administered via injection, remains the intervention for severe reactions.

An overview of 200 years of diabetes treatment

Diabetes treatment became truly effective after the advent of insulin injections in the early 1900s. Diabetes is becoming increasingly common. Current trends estimate one in three Americans will have diabetes by 2050. This overview explores two centuries of diabetes treatment—starting in 1812—and outline potential challenges to treatment and prevention.

The history of many kitchen appliances involves unexpected discoveries and applications, including wartime radar turned hamster defroster and replacing an 'ice king' with heat-stealing boxes.

Aspirin was the first synthesized anti-inflammatory drug

Once used by the ancient Sumarians—extracted from willow bark—but now synthesized in the lab, the active ingredient of this popular medication has been used to treat headaches and pain for thousands of years.

Explaining the icy mystery of the Dyatlov Pass deaths

A decades-old mystery from Soviet Russia could be explained by studying the science of snow. After nine students died on a hiking trip in the Ural Mountains, Soviet investigators found six had perished from hypothermia while three others died from blunt force trauma. The mystery confounded officials for years, and rumors of yeti attacks and similar theories abounded until researchers proposed a new potential culprit: an avalanche.

Who discovered the North Pole?

In 1909, papers reported two separate expeditions had become the first to reach the North Pole. This podcast explores the fascinating and terrifying attempts to reach the remote marker, and the contentious race to become the first person to plant...

The drink that became Coca-Cola was originally called 'Pemberton's French Wine Coca'

When Civil War veteran John Pemberton concocted the drink, he was suffering from both a saber wound and a morphine addiction. He formulated Pemberton's French Wine Coca by copying the popular cocaine-infused Vin Mariani wine that Popes and Presidents drank at the time. This podcast episode details Coca-Cola's origin story, as well as the financial and business strategies it used to get to where it is today.

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

Cross-species transplantation has been attempted in medicine for more than 300 years

Early reported xenotransplantation attempts included 17th century efforts in France to transfuse blood from animals into humans. The poor results prompted France to issue a xenotransplantation ban. In the 19th century, researchers tried animal-to-human skin grafts from species including sheep, rabbits, dogs, cats, rats, chickens, and pigeons.

Most fungal pathogens can't survive the heat of our bodies

Fungal pathogens typically struggle to survive human body temperatures, but researchers hypothesize that global warming conditions will force fungi to adapt to hotter temperatures, with implications for their ability to also survive within our bodies. That type of evolutionary adaptation would lead to more dire health threats for humans.

The oldest medical report of a near-death experience dates to around 1740

In 2014, Dr. Philippe Charlier, a medical doctor and archeologist, found a French medical book from 1740 that described the near-death experience of a pharmacist. Using the Greyson Scale, Charlier found that the incident would have rated at least 12/32, more than high enough to scientifically classify as an NDE by today’s standards.

An antiperspirant ad campaign in the early 1900s dubbed body odor "B.O."

The product was marketed toward women and framed excessive sweating as a medical disorder that needed to be addressed with the product.

CRISPR is a gene-editing tool that lets scientists cut out and replace damaged DNA

One of the most significant advances in modern medical science, CRISPR is a molecular tool for making precise changes to a gene's DNA. The technology has already been approved for treating sickle-cell disease.

Marie Curie developed and trained women to operate mobile X-ray units in World War I

The “petites Curies” allowed medical professionals to identify the severity of wounds without transporting soldiers to medical facilities, expediting treatment and saving lives. The efforts of Curie and other women led to expansions in their rights after the war.

Frequently asked questions on immunotherapy

The Cancer Research Institute takes a close look at immunotherapy and its potential for treating cancer. Immunotherapy teaches the patient's own immune system to recognize and fight cancer cells. It's especially promising as an alternative for cancers that resist chemotherapy and radiation treatment. Have all your questions about the process and its promise here.

10 items that could have saved your life in the trenches

Soldiers settled into trenches to defend themselves against shrapnel and bullets, but weapons such as mustard gas crawled along the ground and settled in these low-lying areas. Here are 10 items that could have helped you survive the trenches, according to this article.

Franklin D. Roosevelt used radio to connect directly with Americans through his 'Fireside Chats'

Beginning in 1933, FDR harnessed the new medium of radio to explain policies and reassure the public during the Great Depression and World War II. His conversational fireside chats revolutionized presidential communication.

History's weirdest weight loss fads, fact-checked

Nothing catches popular attention more than a claim to have found a quick weight-loss technique. History shows us such claims are often unfounded. Dr. Michael Mosley explores extreme weight-loss tips from history, from tapeworms to vinegar diets.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

A painting of coaster-enthusiast Catherine the Great visiting an ice slide

Catherine the Great, the former empress of Russia, loved riding ice slides so much she added wheels to her sleigh to continue the fun during warmer seasons. This 18th century painting depicts her being led from her palace towards the icy slopes.

Remylination is a huge focus for treatment—especially among older adults

Our ability to build new myelin sheaths for nerves degrades with age. There have been research advances boosting cells that support these processes and clear away debris from degraded myelin, but not yet any medications to boost myelination itself, which would aid nerve signaling and preserve nerve function.

Firework or sparkler burns, even if they cover a relatively small area of skin, can significantly affect our range of motion.

See the evolution of Ebola vaccine and treatment development.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

Learn more about the history of fireworks, which dates back to an accidental invention during an alchemist's quest for information about immortality.

Between 10 million and 50 million people in the US develop rashes from poison ivy, poison sumac, and poison oak each year.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

The Russia-Ukraine conflict is the largest ground war in Europe since World War II in casualties, forces mobilized, and displacement of civilians.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

When a Paris department store hesitated to sell Estée Lauder's perfume, she 'accidentally' broke a bottle, causing the smell to spread throughout the store and shoppers to start asking to buy the scent.

For centuries, it was common to sleep in two shifts: a few hours at the beginning of the night, and a longer period beginning around midnight

One of the most famous portraits ever taken is 'Afghan Girl' (1984) by Steve McCurry, yet the subject Sharbat Gula went much of her life without being identified or benefitting from the image's success.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

While the first exchange-traded fund (a 'basket' of different assets that can be bought and sold on a stock exchange) in the US only launched in 1993, the global ETF market has grown to more than $10T in the short time since.

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.

The Brothers Grimm were lawyers before they were storytellers, but became interested in fairy tales as they began investigating how rules and customs had been passed down through cultures.

In 2026, Finland was named the world's happiest country for the ninth consecutive year based on its wealth, social safety network, and high life expectancy, among other factors.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.