Remylination is a huge focus for treatment—especially among older adults

Multiple new research paths may lead to slowing (or even reversing) aging

Aging has always been inevitable, but fasting, epigenetic reprogramming, and parabiosis seem to help people stay young. By studying centenarians, memory, and even the humble roundworm, scientists are looking for the genetic basis to live not just a long life, but a healthy one.

Age, stress, and neurological disorders can prevent memory formation and recall

Neurons transmit signals between one another at sites called synapses. Repeated interactions at these sites improve the efficiency of signal transmissions, making memories involving sensory data associated with those neurons easier to recall. Biochemical factors impacting these synaptic interactions affect memory quality.

Targeting cholesterol metabolism may help address macular degeneration

Research published in 2025, based on human plasma samples and mouse models, indicates that boosting the levels of a molecule called apolipoprotein M in the blood can improve cholesterol processing, helping prevent some cellular damage that contributes to age-related macular degeneration.

Stem cells can reboot the ability of cells to repair themselves

Stem cells—special cells that can self-renew and evolve into new cell types—may provide a path to address aging. Instead of repairing aging cells, stem cells can replace a cell's "repair kit," effectively rebooting the internal processes of tissues to a more youthful state.

MS Drugs reduce inflammation, helping reduce relapses and slow disease progression

Disease-Modifying Drugs calm the body's inflammatory response to help stave off relapses—when new or existing MS symptoms show up for a day or longer. Avoiding smoking, exercising, reducing stress via mindfulness, checking for vitamin D deficiencies, drinking more water and eating well, all can slow disease progression. [The jury's still out on if HRT around the time of menopause may reduce dementia risk](https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(25)00122-9/fulltext) Estrogen can reduce inflammation and support neural growth in the brain, and some research has suggested that beginning hormone replacement therapy around menopause—versus later in life—reduces Alzheimer's disease risk. Still, a recent systematic review concluded that taking HRT didn't affect dementia risk, regardless of when women started taking it, so the science remains unsettled.

Face and neck massages improve the removal of brain cell waste products in mice

A study identified that massaging mice and monkeys' faces and necks enhanced the flow of cerebrospinal fluid. Because CSF has been shown to flush out proteins linked to Alzheimer's and Parkinson's, the research hints at non-invasive treatments to reduce the severity of these diseases.

Sclerosis is the technical term for the lesions or plaques that form without myelin

In the absence of myelin, the body forms scar tissue called sclerosis. That scar tissue hampers nerve's abilities to transmit nerve impulses, essentially acting as a roadblock to speedy communication.

Peptides account for 31 of 370 new drugs approved by US FDA between 2016 and 2023

Among the approved peptide-based drugs is the first-ever treatment for Rett syndrome, a rare inherited neurologic disorder that leads to a progressive loss of motor skills and language. Peptides are particularly attractive for multiple reasons, including their ability to selectively bind to cellular receptors to either activate or inhibit their function.

Stem cell therapies show promise in treating spinal injuries

Researchers have long hoped to use stem cells in regenerative medicine to help patients with spinal cord injuries restore sensation and movement. A 2024 clinical trial illustrates how stem cells derived from patients' fat tissue could help spur the creation of new cells in the spinal cord.

Resistance training is linked to better memory and cognitive function in older adults

Randomized control trials looking at structural neuroimaging and exercise suggest that resistance training in older adults induces structural brain changes that could reduce the risk of Alzheimer's Disease or mitigate its progression. The benefits have been documented when performed at least twice per week for at least six months.

Early research suggests CAR-T therapy might treat scleroderma, reducing skin thickening

Clinical data from a couple patients in 2025 indicated that one experimental CAR-T therapy called rese-cel was able to genetically reprogram T cells to eliminate certain problematic immune B cells that were causing the condition. The therapy reduced skin thickening and allowed the patients to halt using immunosuppressive medications and steroids.

There are multiple types of multiple sclerosis—they differ by attack patterns

When your immune system targets the nervous system, this can cause new or worsening symptoms and the development of scarring or damage within the central nervous system. Relapsing-remitting MS is the most common type of the disease—it includes progressive bouts of attacks that occur months or years apart.

Neural interfaces offer major medical potential but raise serious ethical concerns

Although brain-computer interfaces can help people recover lost functions and allow direct brain-to-computer communication in the future, surveys have shown little public support for using them to boost abilities like memory or focus in healthy people.

How ALS (Lou Gehrig’s Disease) might work, and what scientists are learning about it

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that affects the nerve cells (neurons) controlling muscle movement. As the motor neurons degenerate, they stop sending signals to the muscles, causing progressive muscle weakness and, eventually, death. This three-minute animation focuses on the mechanisms within the motor neurons that cause them to degenerate. By understanding these mechanisms, researchers hope to one day find a cure for ALS.

Developing adaptable brain-body systems lets athletes thrive beyond 30

Success in high-level sports after age 30 relies on physical fitness and building brain resilience through deliberate training, recovery, and stress regulation. This creates a feedback loop where body and mind reinforce each other.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Post-treatment Lyme disease syndrome may be caused by bacterial remnants in the liver

PTLDS, which refers to lingering symptoms of Lyme after antibiotic treatment, is an area of active research. Rodent research published in 2025 suggests that these ongoing symptoms may potentially be due to the body's inflammatory response to lingering cellular components from the bacteria that cause Lyme, Borrelia burgdorferi. In rodents, components of the bacteria's cellular wall may remain in the liver after the bacteria were eliminated with antibiotics.

Smell retraining can help people with anosmia learn to smell again

Olfactory training, which involves repeatedly smelling a selection of strong odors, teaches your brain to familiarize itself with experiencing smells over a lengthy period, typically multiple months. This can be useful for patients who lose their sense of smell for myriad reasons.

Dozens of US research projects focus on the zebrafish's ability to grow new retina cells

The small, striped minnow can repair its optic nerve in just under a week. Scientists are interested in hacking its regenerative capacity to grow new retina cells to treat human eye disorders, including macular degeneration. In 2020, the US National Eye Institute had nearly 80 projects focused on zebrafish.

Is conventional wisdom about amyloid plaques wrong?

Neurobiologist Karl Herrup makes the case for reevaluating current research paradigms and embracing a more comprehensive understanding of Alzheimer's disease. He highlights years of failed clinical trials of drugs reducing amyloid plaques in treating Alzheimer's, the establishment of that theory based on a single patient, and more.

Neural replays in mice help explain food aversions

Princeton University scientists published research in 2025 analyzing how mice learn to associate certain foods or flavors with feeling ill—even when there’s a time gap between eating something and feeling sick. The work, performed with grape Kool-Aid and injections of a substance that made mice sick, traced the literal “gut reaction” of how gut distress signals are linked to neural replays of what the mouse ate.

The neuroscience of REM atonia disorders, where patients act out dreams

What prevents the typical person from acting out their dreams? Temporary paralysis of skeletal muscles, usually leading up to, and during, REM sleep. This academic article and related graphics explore what happens when this process doesn't go as planned, leading to REM sleep behavior disorder.

How psychedelics can potentially reinvent learning

Critical periods, discovered in the early 20th century, describe a period when someone is incredibly sensitive to their environment, and any information learned can stick with them for life. Some researchers argue these states can be "reopened" via psychedelics, which put the mind into a malleable state that can potentially be used to treat conditions ranging from lazy eyes to PTSD.

How the environmental diversity of coral reefs provides potential medical treatments for humans

As immobile animals, corals and the organisms that live on them have evolved a suite of chemical compounds to prevent disease and ward off predators they cannot outrun. These include antibiotics, antivirals, and powerful toxins that target the nervous system and are studied for applications involving pain management and neurological treatments.

A new tinnitus therapy involves mild electric tongue shocks and sound exposures

Lenire, an FDA-approved bimodal neuromodulation treatment approach for tinnitus, aims to teach the brain to distract itself from tinnitus. It includes short-term daily sessions wearing a mouth device that delivers mild electrical pulses to the tongue while listening to different sounds. (Some users may experience a paywall.)

See this 201-level explanation about mitochondria and mitochondrial replacement therapy

This 2022 academic presentation from Stanford University's Dr. Gregory Enns offers a detailed overview about mitochondrial therapy approaches. Enns, a pediatric geneticist, explains how well-functioning mitochondria support the human body.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

Learn how monoclonal antibodies, which mimic the body's antibodies, can fight diseases like Ebola.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Tattoos remain visible on your skin thanks to immune cells called macrophages

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

Some renewable energy sources may weaken the resiliency of electric grids by removing outage buffers provided by coal- and natural gas-fired plants, which provide the system with more time to find a new power source if a plant goes down.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Power lines are dotted with large, brightly colored balls to improve the visibility of these thin wires to helicopters and small planes and help prevent potential crashes.

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

The first steps to rebuilding your credit score include getting to know exactly what's on your credit report and figuring out how far you are from the '700 club,' or 'good score' range.

Before the current East Wing ballroom project, only two White House renovations in the past 100 years cost more than $10M.

Some coin denominations have ridges etched on their sides, partly to prevent counterfeiting, in a practice called 'reeding.'

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.