How psychedelics can potentially reinvent learning

Psychedelic drugs are having a scientific renaissance

After decades of repression, psychedelic research is making a resurgence. Hear from a host of experts in this 20-minute video on what that could mean for the future of mental health. The current science on psychedelics believes LSD can cause a particular brain network to quiet or deactivate.

How can octopuses and MDMA help scientists understand the human brain?

Research shows that psychedelics may induce something called "critical periods" in the adult brain, which can make our brains more open to learning and changing, like they once were back in early childhood. Psychedelics similarly change how social creatures like octopuses behave, which demonstrates that these animals could help us better understand our own neurobiology.

Psychedelics set off a flurry of brain activity that may permanently alter it

The brain seems to experience a sharp increase in communication between areas that generally don't interact. New research suggests a thin, sheet-like gray matter structure tucked deep within the brain, between the insular cortex and striatum, may be the key to this change. The area is centrally located and home to many of the receptors that psychedelics target, potentially rewiring the brain and rewriting thought patterns.

Psychedelics interact with neurotransmitter systems to alter one's perception

LSD, psilocybin, and MDMA can suppress the brain's default mode network and enhance connectivity. Research shows that, when paired with therapy, psychedelics may help treat mental health conditions, including depression, addiction, and PTSD.

Studies of psychedelic use may help shed light on the nature of consciousness

The nature of consciousness—what it is, where it comes from, and how it manifests as moment-to-moment experience—remains under debate by scientists. Recent studies show psychedelics were found to boost low-frequency brain signals known as delta waves, a behavior also seen during dream states.

The neurobiology of meaningfulness: the benefits of psychedelics

Psychedelics produce powerful emotions in its users, including a profound sense of meaningfulness. The philosopher William James called this sense "noetic" in the late 19th century, but for decades researchers avoided studying the effects of such drugs on the brain. However, the recent resurgence in psychedelic research has heightened interest in the relationship between this noetic sense resulting from the therapeutic use of drugs. Learn what researchers have found out here.

What can psychedelics teach us about dying?

Psychedelics have made their way into the world of licensed mental healthcare, and the drugs have been proven to help people process and lessen anxiety and depression. What does this mean for people with terminal illnesses who are afraid of death?

Psychedelic therapy's ethical guidelines (or lack thereof)

With a checkered history of misconduct, how will psychedelic-assisted therapists be held accountable in the emerging legal field? This article explores the nascent field's need for ethical guidelines and clear protection of patient rights when therapeutic breakthroughs teeter "on the edge of consent."

Psychedelic compounds: a visual library

However psychedelic experiences manifest, they all begin with the presence of psychoactive compounds. Learn about their various chemical compositions in this structural library of psychedelic compounds. Clicking on an entry will take readers to a new page where they can learn about the chemistry and pharmacology of each compound, as well as the drug's possible applications.

People with schizophrenia are excluded from psychedelic research

Individuals with this mental health condition are routinely eliminated from any psychedelic research due to concerns about triggering or worsening psychosis. Yet there is little high-quality research in this area, raising questions about if further research into this question is warranted as interest grows in using psychedelics for therapeutic purposes.

How to avoid a 'bad trip' advice includes relaxing your mind if you experience scary things and not fighting the feeling

In this video, Michael Pollan, author of "This Is Your Mind On Plants," underscores the gaps in existing understanding about the substances and recommends only taking guided experiences, for safety and help. He tackles how psychedelics work, explains microdosing and psychedelic risks, how the substances could be used to treat addiction, and the history of psychedelic stigma.

Retracing the 1960s history of dropping out

A core element of the 1960s counterculture was the idea of dropping out of school and the broader technocratic institutions at the time. This push coincided with paranoia over mind control during the Cold War, and as some rogue psychologists advocated for the liberating use of psychedelics.

Can music alter your memories?

You’re familiar with music’s ability to transport you to a past experience, but new research suggests that music can even alter how you remember your past experiences. A team of psychology researchers and music experts recently published a study that demonstrates how music can help shift our emotional recollection of a memory. Read to learn more about the study’s findings and how it could influence therapy practices.

The psychedelic playlist inspired by a Johns Hopkins experiment

Dating back to 1967, the playlist is over seven hours long and organized in such a manner as to echo users’ experiences as their trips rise, crest, and fall. According to the initial creator of the playlist, the music is a “nonverbal support system” that keeps users from prematurely returning to normal consciousness.

Synaptic plasticity allows neurons to communicate effectively and form memories

First proposed in 1949, synaptic plasticity allows the brain to adjust communication strength between neurons. This ability to change synaptic strength—either briefly or over long periods—is essential for learning and memory, with long-term synaptic plasticity forming the basis of how memories are stored.

The 'definitive' history of magic mushrooms

Where did magic mushrooms come from, and how did they get their magical reputation? This article explains the history of the psychedelic fungi from pre-history to now. The earliest concrete evidence of psychedelic mushroom use is 12,000-year-old murals in Northern Australia that portray mushroom iconography. Considering how many species seek out and consume psychoactive substances, such as Siberian reindeer, it's possible human use of these psychedelic mushrooms may predate these murals.

What pupils can reveal about a person’s thoughts and feelings

Eyes have long been said to be the window to the soul. In this article, a psychologist and pupillometrist explores research demonstrating pupils as a window into the mind. Pupils tell us how intensely someone is exerting mental effort, or even reveal what a person is imagining. Read this article for insight into the field of pupillometry and how it can offer insights into our psyches.

The benefits of lucid dreaming

Lucid dreams happen when the dreamer knows they've stepped out of the bounds of waking life. Studies show it can help dreamers cultivate creativity, process grief, and work through trauma. A 2021 study found that 85% of participants with PTSD no longer qualified for the diagnosis after a week of trauma-informed lucid dreaming in which they intentionally witnessed (and therefore integrated) recurring nightmares or changed the outcome completely.

Individuals with synesthesia experience involuntarily overlapping sensations

Tasting words or seeing colors in music results from the brain retaining extrasensory connections from infancy. While most lose these neural pathways during development, about 4% of people are synesthetes, maintaining them without realizing it's unusual.

Restoring vision in impaired patients via CRISPR

Since CRISPR was revealed as a gene editing tool in 2012, it has been on an accelerated track to real-world applications. Among other clinical demonstrations, doctors have now injected a CRISPR treatment directly into eye cells, helping vision-impaired patients see shapes and colors again.

Meta's Quest and other mixed reality devices can make learning new skills easier

PianoVision utilizes the passthrough visibility of a headset to illuminate which keys to play on a real piano or keyboard, providing an immersive, software-based learning alternative to human instruction. Similar apps also offer virtual model replacements for physical devices, such as a virtual piano, to practice with.

Nostalgia is a psychological coping mechanism created from bias

Memories are naturally reconstructed during recall, and research has shown a fading effect bias that causes negative ones to fade more quickly, helping us heal. This creates a natural longing for the past, particularly when faced with loneliness, boredom, or challenging moments in the present.

Researchers believe the brain consolidates memories, processes emotions, and plans for the future during dream states

Developing adaptable brain-body systems lets athletes thrive beyond 30

Success in high-level sports after age 30 relies on physical fitness and building brain resilience through deliberate training, recovery, and stress regulation. This creates a feedback loop where body and mind reinforce each other.

How we learn: comparing classical and operant conditioning

Psychology helps us see how we learn, whether through positive reinforcement or by conditioning a response to a stimulus. Learn about these two key theories in this brief video.

How does the cocktail party effect work?

In the 1950s, British cognitive scientist Colin Cherry started to explore how we could focus our hearing on one single source, even in a noisy environment. This video animation explains the phenomenon known as the cocktail effect and how selective hearing works. Discover how our brain is on the lookout for important or personally relevant information, even as we are occupied in other discussions.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Learn more about the history of fireworks, which dates back to an accidental invention during an alchemist's quest for information about immortality.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Fish populations in the Great Barrier Reef have increased after installing waterproof speakers on the ocean floor that played recordings of sounds from healthy coral reefs.

Watch how algorithms can be designed to train themselves and self-improve without human input, to the point where the optimized code is too complex for programmers to understand.

Poison ivy was sent to Europe in the 1600s as an exotic, ornamental oddity, where it was purposefully grown in the English royal gardens at Kew, the Faculty of Medicine in Paris, and a few other locations.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

Hear 50 years of iconic hip-hop samples, the genre's foundational looped tracks

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

Mid-century modern graphic designers, known for their bright colors and bold lines in advertising, also found success with children's books.

After NASA's Voyager 1 captured Earth as a single pixel as it left the solar system in 1990, astronomer Carl Sagan used the image to reflect on humanity's fragility and the responsibility to protect 'the only world we've ever known.'

The Mona Lisa's celebrity status and repeated restorations have obscured what made the painting so revolutionary for its time

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.