How to avoid a 'bad trip' advice includes relaxing your mind if you experience scary things and not fighting the feeling

Psychedelic side effects, including worsening mental health for some patients, give pause

This article explores whether the therapeutic potential of psychedelic drug use is really as good as current research suggests. Scientists are exploring its applications for conditions ranging from the existential crisis that can accompany terminal diagnoses to chronic mental health conditions, including anxiety and PTSD.

An account of unethical behavior by psychedelic guides

Ethical guidelines and protections have a gossamer grasp in the underground psychedelics movement. This 34-minute podcast episode delves into patterns of deception and abuse by movement leaders through one source's deeply personal tale. This episode, which involves descriptions of sexual violence, is one of many in New York Magazine's Power Trip series, a nine-part investigation into the darker side of the psychedelic renaissance.

Drugs 101: An interactive guide

What's the difference between opioids and psychedelics? This guide details specific drugs and their various associated effects. Drugs in this wheel fall into seven categories: stimulants, depressants, empathogens, psychedelics, dissociatives, cannabinoids, and opioids.

This is the human brain on the world's strongest psychedelic

Within seconds of inhaling a high dose of vaporized synthetic 5-MeO-DMT—a lab-produced substance that otherwise is naturally derived from the glands of the Colorado River toad—it induced slow brain waves. Such waves are typically associated with unconsciousness due to a coma or anesthesia, perhaps explaining why users describe feeling like everything falls away. The compound is currently in clinical trials for treating depression.

Accounts of near-death experiences share similarities with hallucinogens

This short film explores human experiences of dying, blending personal reflections with scientific insight. It aims to illuminate the emotional, psychological, and physiological aspects of that final transition, and draws out similarities of psychedlic drug use and accounts of near-death experiences.

The psychedelic playlist inspired by a Johns Hopkins experiment

Dating back to 1967, the playlist is over seven hours long and organized in such a manner as to echo users’ experiences as their trips rise, crest, and fall. According to the initial creator of the playlist, the music is a “nonverbal support system” that keeps users from prematurely returning to normal consciousness.

The science of fear

The Hidden Brain podcast team explores the science of fear by traveling to a haunted house curated by a scientist to investigate what scares us, and why some people enjoy this sensation more than others.

Unlike milder fears, phobias may get in the way of proceeding with your life

Clinicians may recommend exposure therapy—exposing oneself to the thing triggering fears in some doses—as one way to help overcome a fear.

Scientists are learning to guide your dreams using sound and touch

Researchers are using a technique called "targeted dream incubation"—where stimuli like sounds or vibrations are introduced as you drift off—to influence dream content and potentially improve creativity, memory consolidation, and PTSD treatment. With the same mechanism, companies could theoretically target sleeping consumers with brand suggestions while they're unaware and neurologically susceptible, or assist in reducing nightmares.

Top strategies on how to deal with other people's big feelings

This podcast offers insights on how to effectively talk to others when they're experiencing powerful emotions, and how to simultaneously protect yourself in those situations.

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

How philosophers have approached death throughout history

Philosophers often argue the counterintuitive view that there's actually nothing to fear about death. How do they come to this attitude of acceptance toward fate? This video articulates the views on death from Socrates, Epicurus, and Zhuangzi in a breezy, digestible way.

Kava, kratom, St. John's Wort, and green tea extract present health concerns

Consumer Reports, which tests supplements for safety, urges consumers to avoid these four supplements due to safety warnings from researchers and public health authorities.

American Psychological Association issues recommendations for teen social media use

Listen to this three-minute podcast to learn more about the American Psychological Association's recommendations for teenagers' use of social media. The first report of its kind, it advises parents to closely monitor teens' social feeds during early adolescence, continually screen for signs of problematic use (such as sleep interference), minimize the amount of dangerous content their child is exposed to (such as disordered eating), and limit their teen's use of social media around appearance-related content.

LSD was discovered accidentally after its inventor touched his face and hallucinated

Unlike many drugs, the first time a human ever tripped on acid was recorded first-hand by a scientist. Swiss chemist Albert Hofmann, curious about the "not unpleasant intoxicated-like condition" that overcame him after an accidental exposure, set up a rigorous experiment to test the drug's effects on himself.

Tips for reducing the risk of antimicrobial resistance

Antimicrobial resistance is bad news. But there are lots of things you can do to both protect yourself from superbugs and help keep the problem of antimicrobial resistance from getting worse. This page from the CDC offers clear, straightforward guidelines that can help keep you—and your loved ones—healthy.

Expert predictions on the metaverse

Experts are split about the likely evolution of a truly immersive metaverse. Many worry current online problems may be magnified if Web3 development is led by those who built today’s dominant web platforms.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Microplastics 101: What we know about the contaminants invading our bodies

Fifty-one trillion particles of microplastics float in our oceans. Yet there is very little science of how this affects our health. This quick 2-minute video explains the dangers of microplastics.

How to think yourself into health

Can the right thoughts lead to a stronger immune system? Neuroimmunologists like Hai Qi study how drugs targeting the brain, as well as thought exercises, can prompt stronger immune responses to infection. This six-minute video investigates the radical claims.

The lack of guidance on getting off GLP-1s leaves patients at risk

Dr. David Kessler, former FDA Commissioner and public health leader, explores how these drugs override the brain’s reward-driven eating habits but have notable side effects. These include developing eating disorders, muscle loss, and intestinal obstruction.

Ray Dalio credits much of his success to his transcendental meditation practice

Dalio took up transcendental meditation after learning that The Beatles practiced it on a trip to India in 1968. He says the practice allows him to clear his mind, be more creative, and unlock his subconscious.

Natural toxins produced on plants or consumed by animals may cause food poisoning

When humans eat plants with certain natural toxins on them—including a family of toxins called aflatoxins that fungi produce on crops like peanuts and corn— they can become ill with food poisoning. Toxins can still harm humans even if animals or plants appear fine to the human eye. The World Health Organization advises that we should throw away moldy or discolored foods, refrain from eating wild plants or mushrooms that aren’t definitively nonpoisonous, and remember that just because something is “natural” it’s not always safe to eat.

Eliminating distractions is essential to improving one's attention span

Setting a baseline, removing distractions, establishing focus rituals, taking breaks, and finding purpose in your task are five science-backed practices that can help address a short attention span. Bestselling author Daniel Pink breaks down how to approach each part of the plan and introduce these habits to your life today.

'The opposite of addiction isn't sobriety—it's human connection'

This thought-provoking TED talk from journalist Johann Hari challenges conventional wisdom about addiction, with a special focus on his global research investigating its root causes. Through personal stories and scientific evidence, Hari debunks some of the most common myths around addiction.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure

This podcast takes on the thorny mismatch between recent research linking herbicide exposure to Parkinson's disease and federal and state regulators' conclusions that there is insufficient evidence to establish causality. Though the main company that produces the herbicide Paraquat has recently stopped making it, dozens of others continue to do so, prompting concerns from some Parkinson's patients and scientists about disease risk and the pace of scientific answers. 

What is psychoanalysis?

This nine-minute video, the first of a four-part series, seeks to answer the questions: what is psychoanalysis, and is it weird? The answer to the latter question is overwhelmingly yes. The answer to the first question is a bit...

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

Fear or disgust related to clusters of holes and cracks, called trypophobia, may stem from evolutionary processes to help us avoid pathogens.

An investigation suggests a Scottish island became awash in forever chemicals via seafoam and seaspray—raising questions about what that means for the safety of other coastal areas.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

This poison ivy knowledge quiz—accompanied by photos of the plant's varied forms—may help you identify this common rash-inducing growth.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Researchers believe the brain consolidates memories, processes emotions, and plans for the future during dream states

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

After NASA's Voyager 1 captured Earth as a single pixel as it left the solar system in 1990, astronomer Carl Sagan used the image to reflect on humanity's fragility and the responsibility to protect 'the only world we've ever known.'

SpongeBob exemplifies Aristotle's philosophy for living well because he understands that happiness doesn't come from external factors like money, recognition, or power.

This site reaches millions of visitors who are tired of AI chatbots and seeking human connection. Pretend to be an AI chatbot and ask questions, provide answers, and draw for people in real time.

A 2019 Facebook event called on attendees to "Storm Area 51, They Can't Stop All of Us," resulting in countless memes, the creation of a music festival, and eventually the arrests of those who did try to approach the area.

How the most famous Ebola book, The Hot Zone, which sold 3.5 million copies and was translated into 30 languages, got aspects of the disease so wrong.

Netflix profits when you're not watching, and its movies are designed that way—read a detail-rich critical essay exposing lesser-known Netflix takes

Prince's sexually explicit 1984 track 'Darling Nikki' attracted the ire of the Parents Music Resource Center, an advocacy group that inspired the Parental Advisory sticker, even though the song ends with a Christian message.

Explore the history, structure, and species of Australia's Great Barrier Reef with this interactive journey narrated by Sir David Attenborough.

Georgia O'Keeffe's flower paintings are often assumed to be sexual, though the artist claimed she was simply interested in highlighting the beauty of flowers that most people neglect

Hear 50 years of iconic hip-hop samples, the genre's foundational looped tracks

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

The first horror movie is believed to be George Méliès' 1986 short 'The Haunted Castle,' which pioneered the use of special effects

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.