Studies of psychedelic use may help shed light on the nature of consciousness

Researchers recently took an unprecedented look at the neural effects of psychedelics

According to analysis published in 2026 that looked at more than 500 brain scans pooled from 267 people who took psychedelics, the drugs increase connectivity between different brain regions within minutes of taking them, including transmodal networks (tied to thinking) and unimodal networks (involved in visual and sensory perception).

How can octopuses and MDMA help scientists understand the human brain?

Research shows that psychedelics may induce something called "critical periods" in the adult brain, which can make our brains more open to learning and changing, like they once were back in early childhood. Psychedelics similarly change how social creatures like octopuses behave, which demonstrates that these animals could help us better understand our own neurobiology.

The neurobiology of meaningfulness: the benefits of psychedelics

Psychedelics produce powerful emotions in its users, including a profound sense of meaningfulness. The philosopher William James called this sense "noetic" in the late 19th century, but for decades researchers avoided studying the effects of such drugs on the brain. However, the recent resurgence in psychedelic research has heightened interest in the relationship between this noetic sense resulting from the therapeutic use of drugs. Learn what researchers have found out here.

Mental health applications of psychedelics

Scientists are investigating psilocybin, ketamine, LSD, and MDMA (also known as ecstasy) as potential treatments for mental health issues. These drugs enable an altered state of consciousness, which can have beneficial or harmful impacts depending on the nature of the experience. Research suggests these drugs can be effective in treating substance use disorders, mental health conditions, including depression and anxiety, and psychiatric disorders, including schizophrenia.

Psychedelic drugs are having a scientific renaissance

After decades of repression, psychedelic research is making a resurgence. Hear from a host of experts in this 20-minute video on what that could mean for the future of mental health. The current science on psychedelics believes LSD can cause a particular brain network to quiet or deactivate.

How psychedelics can potentially reinvent learning

Critical periods, discovered in the early 20th century, describe a period when someone is incredibly sensitive to their environment, and any information learned can stick with them for life. Some researchers argue these states can be "reopened" via psychedelics, which put the mind into a malleable state that can potentially be used to treat conditions ranging from lazy eyes to PTSD.

Physiological changes to the brain on LSD can be captured via MRI

Psychedelics like LSD often take users on novel experiences that can result in lasting shifts in perspective and behavior. See how LSD affects brain activity in this video that details how scientists visually captured the psychedelic's effect for the first time.

This is the human brain on the world's strongest psychedelic

Within seconds of inhaling a high dose of vaporized synthetic 5-MeO-DMT—a lab-produced substance that otherwise is naturally derived from the glands of the Colorado River toad—it induced slow brain waves. Such waves are typically associated with unconsciousness due to a coma or anesthesia, perhaps explaining why users describe feeling like everything falls away. The compound is currently in clinical trials for treating depression.

How new research sheds light on why we dream

The theory of where dreams originate began shifting from ancient mystical explanations to modern scientific ones at the beginning of the 20th century. Now, scientists have the ability to track electrical activity in the brain, solidifying some of the field's softer science into observable data and giving rise to sleep labs.

How seizures (potentially) alter consciousness

Seizures occur when intense electrical activity floods the brain, prompting significant loss of self-control and a variety of sensory disruptions and hallucinations. Cultures interpret the episodes differently, with many contemporary norms viewing them as negative while others characterize them as intense spiritual occasions. Author Fyodor Dostoyevsky viewed his seizures this way, as well as cultures in Mongolia, some Shamanic indigenous religions, and others.

Some scientists argue NDEs are constructed by the brain, not actually experienced

Despite the powerful memories associated with NDEs, scientists question the idea that the experiences prove consciousness endures after death, opting instead to find physiological explanations for common reports of out-of-body experiences, euphoric and lucid thinking, and more.

The debate on why humans are conscious—and what that means

Understanding what consciousness is, and why and how it evolved, is perhaps the greatest mystery known to science. Watch interviews with the world's leading experts on what it is and whether we'll ever know.

Delta brain waves happen during deep sleep, while REM cycles resemble being awake

As the brain cycles from wakeful rest to deep sleep, different brain waves emerge. Alpha waves occur during restful waking states, while theta waves can be associated with light sleep and meditation. Delta waves are observed during deep sleep—but REM cycles more closely resemble active awake states.

Accounts of near-death experiences share similarities with hallucinogens

This short film explores human experiences of dying, blending personal reflections with scientific insight. It aims to illuminate the emotional, psychological, and physiological aspects of that final transition, and draws out similarities of psychedlic drug use and accounts of near-death experiences.

Researchers believe the brain consolidates memories, processes emotions, and plans for the future during dream states

Scientists are studying dying patients' brain activity in the final moments of life

In the final moments of life there are distinctive bursts of coordinated neural activity. Researchers are interested in parsing that data to better understand the dying process and also exploring how this data relates to our understanding of consciousness.

Some founders of quantum mechanics thought consciousness could influence phenomena

Since quantum systems exist as a superposition of states before producing a definitive outcome, some quantum pioneers wondered if the act of conscious observation was what collapsed the wave function of possibilities into one state.

Humans experience the world subjectively. What does that mean for scientific research?

When you close your eyes, do you see static or colorful patterns or an "intrinsic grey" known as Eigengrau in German? This variation of our internal experiences is just the tip of the iceberg, one that scientists are increasingly studying and...

Panpsychism suggests that all matter possesses consciousness

The theory describes consciousness as a fundamental, ubiquitous property, rather than separate or emerging from matter. Cosmopsychism posits that the universe is conscious, while some critics argue that consciousness itself may be an illusion.

How your subconscious influences your decisions

How much of your desires and daily choices are truly yours? One of the most effective ways to influence someone's subconscious is when they're asleep. To study this possibility, researchers trained participants to be able to dream lucidly, a phenomenon that occurs when a dreamer knows they're dreaming.

The benefits of lucid dreaming

Lucid dreams happen when the dreamer knows they've stepped out of the bounds of waking life. Studies show it can help dreamers cultivate creativity, process grief, and work through trauma. A 2021 study found that 85% of participants with PTSD no longer qualified for the diagnosis after a week of trauma-informed lucid dreaming in which they intentionally witnessed (and therefore integrated) recurring nightmares or changed the outcome completely.

Neural rhythms shape how we move, focus, remember, and interact with the world

Millions of neurons in the brain produce rhythmic electrical signals, or brain waves, that guide physical movement and help form and store memories. Researchers also use these rhythms to create brain-computer interfaces, letting people control devices using only their thoughts.

Brain wave-reading earbuds are being used by companies to study workplace performance

Limited safeguards prevent governments from accessing and companies from sharing brain data. Foreign governments may also be developing technology to spy on and potentially disrupt human thoughts.

Ray Dalio credits much of his success to his transcendental meditation practice

Dalio took up transcendental meditation after learning that The Beatles practiced it on a trip to India in 1968. He says the practice allows him to clear his mind, be more creative, and unlock his subconscious.

Surrealism toyed with ideas from psychoanalysis

The movement's artists were interested in the ideas being explored in the burgeoning fields of psychology and psychoanalysis. Dalí, in particular, often created works that toyed with Freudian theories.

Inside the rise of focus music

Any casual YouTube or Spotify user has likely stumbled upon a playlist called "lo-fi beats to study and relax to" while searching for new music. Those "lo-fi beats" actually represent a growing genre of music called "focus music." Spotify, for instance. saw a 50% increase in listening time for focus playlists in its 2023 Wrapped report. This article explains why productivity tunes are on an upswing right now. Read it here.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Massive blooms of microscopic plankton called dinoflagellates produce the neon blue light seen in glowing tides.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

An investigation suggests a Scottish island became awash in forever chemicals via seafoam and seaspray—raising questions about what that means for the safety of other coastal areas.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

A researcher recently discovered an interview from 1967 between groundbreaking journalist Joan Didion and the Grateful Dead, years before the band became an institution.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

According to the physics of black holes, our 4D reality may be a hologram—a projection of information coded on a 2D surface on the edge of the universe.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Chaos theory—informally known as the butterfly effect—is the reason why weather forecasts are presented with probabilities rather than certainties.

SpongeBob exemplifies Aristotle's philosophy for living well because he understands that happiness doesn't come from external factors like money, recognition, or power.

Georgia O'Keeffe's flower paintings are often assumed to be sexual, though the artist claimed she was simply interested in highlighting the beauty of flowers that most people neglect

Salvador Dalí believed he was his own dead brother, who had died nine months before he was born

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

Before humans, the Soviet Union and the United States sent animals—including apes, dogs, and cats—to space during the Space Race.

One disco producer saw 'Star Wars' four times on its opening weekend and was so inspired that he recorded the album 'Star Wars and Other Intergalactic Funk,' which produced a chart-topping single.

An initial public offering or 'IPO' is the process of a private company becoming public by putting shares of the company on the stock market for purchase.