How seizures (potentially) alter consciousness

Studies of psychedelic use may help shed light on the nature of consciousness

The nature of consciousness—what it is, where it comes from, and how it manifests as moment-to-moment experience—remains under debate by scientists. Recent studies show psychedelics were found to boost low-frequency brain signals known as delta waves, a behavior also seen during dream states.

Losing a brain-computer interface can trigger lasting psychological distress

A clinical trial participant with severe epilepsy described becoming “one” with her implant after it gave her unprecedented control over her seizures. When the device was removed due to the company shutting down, she experienced deep emotional trauma and a sense of personal loss.

NDEs typically change people's outlooks drastically and can prompt depression

The phenomena are regularly categorized as hallucinations, but some specialists are interested in their psychological nuances. Many survivors report feeling less anxiety about death, though some surveys show the experiences can increase physiological sensitivities.

Historians theorize Vincent Van Gogh suffered from Ménière's disease or epilepsy

A century after researchers suggested he suffered from epilepsy, some researchers in the 1990s began to support an alternate diagnosis: Ménière's disease, since he had suffered from severe, repeated attacks of disabling vertigo. Still, some researchers remain skeptical of the Ménière's diagnosis. One posits that Van Gogh had temporal epilepsy complicated by his absinthe consumption.

Why might someone want to stay in psychosis?

Author Abigail Gosselin writes that her verbal auditory hallucination, often assumed by others to be harmful or threatening in nature, offered a salve to loneliness, even as it told her to kill herself. This perceived benefit and others Gosselin shares offer insight into why people in psychosis may struggle to adhere to treatment and medication plans.

Why 'spacing out' or dissociating may help reduce trauma awareness

Dissociation may have developed as a defense mechanism in the brain to help navigate intense emotional or physical situations by providing out-of-body experiences that put distance between the mind and the environment. However, in about 1.1% and 1.5% percent of the general population, a severe form of this separation can produce alternate identities, or alters.

Schizophrenia literally means 'split mind'—a reference to patients' break with reality

Contrary to the name, patients do not have multiple personalities. Rather, the split mind refers to the sufferers' inability to distinguish reality from hallucinations when they are aware and awake. Cognitive difficulties, including challenges focusing and communicating are also common among those with schizophrenia, as well as auditory and visual hallucinations.

A mescaline-induced hallucination stayed with Jean-Paul Sartre throughout his life

In 1935, Sartre was injected with mescaline, a psychedelic drug that was then used to treat alcoholism and depression, by his friend at the Hôpital Sainte-Anne in Paris. It was not a good trip: Sartre saw nightmarish crabs for days and suffered a mental breakdown. For the rest of his life, crustaceans like the ones he saw during the hallucination appeared in his works.

For most of recorded history dreams were considered divine in origin

The first venture into modern dream interpretation may have been when ancient Greek philosopher Heracleitus proposed dreams were created within the mind. In the late 1800s, the rise of psychoanalysis theorized that dreams content revealed truths about one's psyche, while the invention of the electroencephalogram linked dreams to brain functions.

Delirium tremens is the most severe form of alcohol withdrawal

Due to the impact of alcohol on the central nervous system, withdrawal from the drug can cause severe effects. Roughly 1% to 1.5% of heavy drinkers will experience delirium tremens, which includes tremors, seizures, hallucinations, and more. Onset typically occurs 48-72 hours after the last drink.

Individuals with synesthesia experience involuntarily overlapping sensations

Tasting words or seeing colors in music results from the brain retaining extrasensory connections from infancy. While most lose these neural pathways during development, about 4% of people are synesthetes, maintaining them without realizing it's unusual.

Sleep paralysis occurs when the body fails to 'unfreeze' in sync with waking

When the body falls into a deep enough phase of sleep, it paralyzes certain parts of itself so the brain can't force it to physically act out dreams. This well-known but little-understood phenomenon happens when the brain awakens early and typically results in haunting hallucinations and reports of supernatural terrors.

Four in 10 CPR patients report consciousness not captured by standard measures

A recent study found people revived by CPR after cardiac arrest reported they experienced some amount of consciousness during clinical death, suggesting our brains are capable of thought and memory for significantly longer after death than previously thought.

The myth of sugar rushes vs. the reality of sugar crashes

It's generally accepted that sugar rushes are a myth, and that hyperactivity is a more psychological experience. However, there is real science behind the rare sugar crash that primarily impacts those with diabetes. Read this article to understand how historical and cultural factors have shaped sugar perceptions, and how low blood sugar can trigger shakiness, fatigue, weakness, and more in diabetes patients.

Addictive drugs can cause dopamine levels to become ten times higher than normal

Now recognized as a physiological brain disease, addiction rewires the brain's reward system to make drugs feel necessary and weaken self-control by dulling the relative effects of natural rewards like food and social connection.

Mental health symptoms may manifest differently across cultures

Mental health, like physical health, is imbued with values, beliefs, and traditions. Symptoms of distress are not universal and may differ based on racial, ethnic, and cultural contexts. Because mental health may be stigmatized or communities may have varying belief systems about causes of mental health challenges and how to fix them, it may affect how symptoms manifest. Chest pain, for example, may be a sign of mental distress—not the need for a doctor.

What happens to the brain during migraine?

Migraine is a neurological condition that can cause debilitating symptoms across various bodily functions. So, what exactly is happening in the brain during these attacks? This five-minute video briefly overviews the internal machinations behind the painful episodes. An incapacitating headache is a common symptom of migraine, though migraine can occur without any headache.

The benefits of extreme pain rituals, explained

We naturally avoid pain and see it as a negative experience. But many traditional cultures incorporate extremely painful rituals into their religious ceremonies, claiming they, in fact, provide ample benefits. Researchers were able to observe boosts in happiness and a sense of belonging in a tribe of Mauritians after they undertook a rigorously painful religious ritual. Read about the study here.

Anesthetics slow brain activity by promoting inhibitory neurotransmitters

Drugs like propofol and isoflurane increase activity at the GABA receptor, which opens chloride channels. These ions enter neurons and hyperpolarize them, making them less likely to fire. Dexmedetomidine instead blocks norepinephrine receptors in the brainstem to sedate patients.

Heat exhaustion is the most likely diagnosis if someone is talking clearly

Heatstroke, true to its name, looks more like a stroke. Its symptoms include severe disorientation, irritability, and seizures, among others. A patient does not need to have collapsed in order to have exertional heatstroke, but if someone is talking clearly, they likely have heat exhaustion, and it hasn't progressed to heatstroke.

There are at least 6 fascinating examples of mind-controlling parasites

Parasitic organisms—including flatworms and barnacles, not just fungi—can modify animal behavior. They can give rise to dancing fish, pulsating snails, suicidal rats, and more. Though some of these pathogens can sicken humans, there is no strong evidence that any can control human behavior.

'1440 Explores' Episode 3: Why We See Ghosts and What Isn't There

Every culture has them—restless spirits, haunted houses, things that go bump in the night. But why do we believe in ghosts? Psychologist and skeptic Dr. Chris French joins host Sony Kassam to explore the science behind the supernatural, from sleep paralysis and hallucinations to the brain's pattern-making instincts. Together, they uncover why our minds see meaning—and sometimes ghosts—where none exist, and what that reveals about fear, memory, and our need to believe in something beyond the grave.

'Blackout challenge' can cause brain damage or death in under 5 minutes

A social media trend that encourages viewers to asphyxiate themselves until they lose consciousness in the hopes of feeling "high" or euphoric has garnered the interest of teens and adolescents, with dangerous results. Variations of this deadly challenge have been adolescent trends every few years.

How the feared self fuels OCD

Obsessive-compulsive disorder is characterized by intrusive thoughts that prompt people to enact compulsions—behaviors intended to relieve the anxiety or stress from the obsession. A significant intrusive thought OCD sufferers endure is the fear they will become a dangerous or immoral person. Therapeutic approaches try to show patients this is just a story that can be set aside.

Defining Dalí's surreal aesthetic

Salvador Dalí is known for his modernist paintings, but his surreal aesthetic has lived on long after his passing, with elements of his art making their way into fashion, film, and interior decorating. This incisive Artnet explainer unpacks the elements that make up Dalí's larger artistic vision and highlights the ways they still appear throughout popular culture.

Researchers believe the brain consolidates memories, processes emotions, and plans for the future during dream states

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

The Dracula character, now seen as the vampire archetype, was inspired by a seafood-induced nightmare its creator experienced.

See these 16 pieces of art evoking phobias of snakes, flying, spiders, and more. 

Salvador Dalí believed he was his own dead brother, who had died nine months before he was born

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

Firework or sparkler burns, even if they cover a relatively small area of skin, can significantly affect our range of motion.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

Discover the catastrophic consequences of a failure of the US electrical grid—something that is more likely than many Americans think.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

'Shogun,' a 1980s TV series, helped popularize sushi in the US by stimulating an American interest in Japanese culture.

A 2019 Facebook event called on attendees to "Storm Area 51, They Can't Stop All of Us," resulting in countless memes, the creation of a music festival, and eventually the arrests of those who did try to approach the area.

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Cultural norms about how to handle the bodies of loved ones in communities in West Africa have hampered Ebola responses.

The Mona Lisa's celebrity status and repeated restorations have obscured what made the painting so revolutionary for its time

Waves off the coast of Nazaré, Portugal, can reach over 100 feet and are caused by the area's deep underwater canyon geography

NBA superstar Victor Wembanyama spent the 2025 summer training with monks in central China to enhance his body and mind.

Explore a list of the 100 best novels of all time, compiled by some of the world's best living writers, including Salman Rushdie, Stephen King, and Jennifer Egan.

44% of Americans say they pray at least once a day—discover how your state's religiosity stacks up against the rest of the country.

Pure water does not conduct electricity because this flow of energy requires the movement of charged particles, and water is a neutral molecule.

SpongeBob exemplifies Aristotle's philosophy for living well because he understands that happiness doesn't come from external factors like money, recognition, or power.

Watch contemporary footage covering the US-backed Shah of Iran fleeing the country in the face of the 1979 Iranian Revolution

Explore chaos in this simulation of two double pendulums, where small differences in the release angles produce wildly different outcomes.