Schizophrenia literally means 'split mind'—a reference to patients' break with reality

Schizophrenia is challenging to diagnose and treat

The disorder is diagnosed by a clinician who observes behaviors and medical history and may run additional tests to rule out other explanations for symptoms including physical injury or other mental health disorders. But, ultimately, it's largely a diagnosis of exclusion—since there is no definitive test for the disease. Antipsychotic medications can help control its symptoms for some patients, but there is no cure for schizophrenia.

The term schizophrenia was coined by Swiss psychiatrist Eugen Bleuler in 1908

He launched the word during a lecture at the German Psychiatric Association in Berlin. In his talk he focused on the splitting of psychic functioning as a defining feature of the disease and noted it wasn't associated with dementia or factors like early puberty onset.

Schizophrenia symptoms often appear suddenly

Schizophrenia is a particularly shocking mental illness because its symptoms may appear seemingly without any prior signs of illness after a person has had no symptoms for the first couple of decades of their life. Among teens, symptoms may look like typical adolescent behaviors—withdrawal, being irritable, and having trouble sleeping.

Less than 1% of people globally have schizophrenia, a syndrome strongly linked to genetics

Schizophrenia's causes remain largely unknown, though scientists suggest it's caused by multiple factors. Its symptoms include disruption of thought processes rather than the exhibiting of multiple personalities. This brief video provides an overview of the condition.

People with schizophrenia are excluded from psychedelic research

Individuals with this mental health condition are routinely eliminated from any psychedelic research due to concerns about triggering or worsening psychosis. Yet there is little high-quality research in this area, raising questions about if further research into this question is warranted as interest grows in using psychedelics for therapeutic purposes.

Schizophrenia is being studied with pea-sized 'mini-brains'

Brain organoid research is enabling researchers to study distinct electrical firing patterns associated with schizophrenia. These "mini-brains" that are constructed in the lab from patients' cells could lead to better diagnosis approaches and drug development.

Misfired motor signals may explain why many people with schizophrenia hear voices

Up to 80% of schizophrenia patients may have auditory hallucinations. Recent research concluded that this symptom may be from misfired motor signals that feed into each other, essentially failing to suppress certain sensory neural activities and that resulting overexcitment fuels hallucinations. The finding suggests that, one day, magnetic pulses might be used to stimulate specific nerves to better regulate the errant signals and reduce or stop hallucinations. (Some users may encounter a paywall.)

People with schizophrenia have triple the risk of developing diabetes

It remains contentious if something inherent about the disease or antipsychotics' side effects (weight gain) are mostly to blame. Some newly diagnosed schizophrenia patients already have insulin resistance, raising questions about if patients' brains are getting enough energy from glucose, and if dietary changes—like a high-fat, low-carbohydrate, moderate-protein diet—may help alleviate symptoms.

Wearing a 'schizophrenia simulator,' designed to build empathy for patients, CNN's Anderson Cooper finds he struggles to function

Donning headphones that play a track mimicking the auditory hallucinations common in schizophrenia, Cooper finds he is very distracted, disconcerted, and frustrated. The auditory track aims to help listeners build empathy with patient populations by understanding the challenges they face in daily life.

Multiple sclerosis means 'many scars'

That's a reference to the scarring or lesions that occur in the brain, spinal cord, and elsewhere whenever the immune system has a flare-up. The immune system attacks the myelin because it incorrectly responds as if it's a threat, damaging the body's ability to transmit electrical signals effectively from areas of the body to the brain.

Why might someone want to stay in psychosis?

Author Abigail Gosselin writes that her verbal auditory hallucination, often assumed by others to be harmful or threatening in nature, offered a salve to loneliness, even as it told her to kill herself. This perceived benefit and others Gosselin shares offer insight into why people in psychosis may struggle to adhere to treatment and medication plans.

Deinstitutionalization in the 20th century unintentionally led to the incarceration of schizophrenia patients

Activism to shut down problematic asylums in the mid-20th century led to the community release of many patients with severe mental illnesses, including schizophrenia, but without adequate support, this deinstitutionalization in the 1960s and 1970s led to a significant increase in patients with schizophrenia ending up in prisons and homeless shelters.

Why 'spacing out' or dissociating may help reduce trauma awareness

Dissociation may have developed as a defense mechanism in the brain to help navigate intense emotional or physical situations by providing out-of-body experiences that put distance between the mind and the environment. However, in about 1.1% and 1.5% percent of the general population, a severe form of this separation can produce alternate identities, or alters.

How seizures (potentially) alter consciousness

Seizures occur when intense electrical activity floods the brain, prompting significant loss of self-control and a variety of sensory disruptions and hallucinations. Cultures interpret the episodes differently, with many contemporary norms viewing them as negative while others characterize them as intense spiritual occasions. Author Fyodor Dostoyevsky viewed his seizures this way, as well as cultures in Mongolia, some Shamanic indigenous religions, and others.

Mental health is much more than the absence of mental illness

It's a state of well-being that allows individuals to cope with daily stressors, realize their abilities, learn and work effectively, and contribute to their overall community. Inextricably linked to physical health, modern science indicates that mental health is a central component of our overarching ability to function and enjoy life.

What it's like to live with insomnia

The biological process Shakespeare referred to as the chief nourisher of life's feast is necessary for the body and mind to rest and repair from the activities of daily life. As sleep evades the exhausted, sufferers also lose emotional stability, mental clarity, social connections, and more while simultaneously gaining waves of interrupted biological processes that can lead to disease and death.

What is mixed reality?

Mixed reality is a technology that blends the physical and digital worlds, allowing virtual and real objects to coexist and interact in real-time. It combines elements of both virtual reality and augmented reality, enabling users to perceive and manipulate digital content as if it were part of their physical environment.

Explaining the many-worlds interpretation

A mind-bending, jargon-free account of the popular interpretation of quantum mechanics, helping to explain how something can be in two states at once.

Memory is a complex narrative constructed from real and imagined experiences

Memories start with perception and are processed in the hippocampus. Different types of memories use different brain regions, and episodic memory, which is involved in recalling one's life events, is more susceptible to decay than semantic memory, which is involved in general information.

Obsessive compulsive disorder is a mental health disorder, not a personality quirk

In popular culture OCD has been incorrectly overused to describe neatness or perfectionistic behaviors, but the disorder involves intrusive thoughts and compulsive behaviors that take over a person's actions.

Some people really cannot imagine. Literally.

There are many people who are astonished to discover that their complete lack of ability to picture visual imagery is different from the norm.

The myth of multitasking's prestige

In this article, renowned neurologist Richard Cytowic seeks to expose multitasking as a fool’s errand. Cytowic explains how the brain, like a computer, switches between tasks rather than handling multiple tasks at once. He shares that attempting to focus on multiple activities at the same time consequentially decreases the brain's ability to ignore distractions, maintain focus, and organize information. Instead, he suggests, try to focus on completing one thing at a time.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

The word 'vertigo' derives from the Latin 'vertere,' meaning to turn

Beyond the word's origin, this article makes clear that fuzzy definitions of the disorder make it confusing for patients to describe it.

A first-person account of receiving an Alzheimer's diagnosis

Having Alzheimer's is a bit like having a part of your brain sliced away each day, according to author Greg O'Brien. This 34-minute podcast episode introduces O'Brien and his co-host, author David Shenk, as the two embark on a multi-season conversation on Alzheimer's disease and O'Brien's diagnosis.

Hitchcock believed film editing was a form of mosaic

In this interview, Hitchcock explains why he doesn't like the term "cutting" because it implies "severing something." Instead, he believes cuts in film allow for a fuller picture and uses the famous shower scene from 1960's "Psycho," which he says uses over 78 different cuts, as an example.

Researchers believe the brain consolidates memories, processes emotions, and plans for the future during dream states

Salvador Dalí believed he was his own dead brother, who had died nine months before he was born

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Existentialist writer Jean-Paul Sartre coined the famous phrase 'Hell is—other people' in his play 'No Exit'

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

According to the physics of black holes, our 4D reality may be a hologram—a projection of information coded on a 2D surface on the edge of the universe.

Shooting stars, or meteors, are fragments of asteroids and comets that burn up as they enter Earth's atmosphere, creating streaks in the sky called meteor showers.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

Ebola is a filovirus, meaning it resembles a thread under a microscope, though it sometimes twists and can resemble a bowl of spaghetti.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

Explore chaos in this simulation of two double pendulums, where small differences in the release angles produce wildly different outcomes.

Use this calculator to find the dollar value of your mental load, from meal planning to coordinating after-school care for your children.

See a 3D reconstruction of Tenochtitlan, the Aztec capital that was home to an estimated population of 200,000 to 400,000.

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

Legendary architect Frank Lloyd Wright designed the SC Johnson headquarters in Wisconsin, aiming to make a cathedral-like workplace

One disco producer saw 'Star Wars' four times on its opening weekend and was so inspired that he recorded the album 'Star Wars and Other Intergalactic Funk,' which produced a chart-topping single.

The rivalry between Alexander Hamilton and Thomas Jefferson centered on federalism—the question of how much power the federal government should hold relative to the states.

See photos of Meteora, a mountainous site in central Greece, home to 14th-century monasteries perched atop soaring outcroppings.

Comedy legend Catherine O'Hara, star of 'Schitt's Creek' and 'Home Alone,' quit 'Saturday Night Live' after just one week to return to her old job.