Misfired motor signals may explain why many people with schizophrenia hear voices

Wearing a 'schizophrenia simulator,' designed to build empathy for patients, CNN's Anderson Cooper finds he struggles to function

Donning headphones that play a track mimicking the auditory hallucinations common in schizophrenia, Cooper finds he is very distracted, disconcerted, and frustrated. The auditory track aims to help listeners build empathy with patient populations by understanding the challenges they face in daily life.

Why might someone want to stay in psychosis?

Author Abigail Gosselin writes that her verbal auditory hallucination, often assumed by others to be harmful or threatening in nature, offered a salve to loneliness, even as it told her to kill herself. This perceived benefit and others Gosselin shares offer insight into why people in psychosis may struggle to adhere to treatment and medication plans.

People with schizophrenia are excluded from psychedelic research

Individuals with this mental health condition are routinely eliminated from any psychedelic research due to concerns about triggering or worsening psychosis. Yet there is little high-quality research in this area, raising questions about if further research into this question is warranted as interest grows in using psychedelics for therapeutic purposes.

If hearing is damaged, the brain may amplify remaining sounds, perhaps causing tinnitus

Recent mouse brain and ear imaging revealed that the creature compensates for hearing loss by sending signals to the cochlea in the inner ear. This triggers nerve fibers in the inner ear to increase volume and become more sensitive. Learning about these boosted-sensitivity messages from the brain to the cochlea—if they're similar in humans—might help explain tinnitus and fuel experimental approaches to turn down that sensitivity.

Schizophrenia increases heat death risks in several complex ways

Evidence shows that people with schizophrenia have an inherently harder time regulating internal body temperatures. They may also struggle to find safe shelter during extreme heat, and their prescribed antipsychotic medications often have dehydrating effects, collectively elevating the risk of heat-related illness and death, as illustrated by this article that focuses on the final days of Stephan Goodwin's life in 2022. (Some users may encounter a paywall.)

80% of schizophrenia cases may be inherited

Some research suggests that anywhere between 60% and 80% of people with schizophrenia had genes that predisposed them to the syndrome. That high rate has fueled interest in further exploration of what environmental and lifestyle factors cause some people with that genetic risk to develop the disease when others with the same genetic risks do not.

Schizophrenia literally means 'split mind'—a reference to patients' break with reality

Contrary to the name, patients do not have multiple personalities. Rather, the split mind refers to the sufferers' inability to distinguish reality from hallucinations when they are aware and awake. Cognitive difficulties, including challenges focusing and communicating are also common among those with schizophrenia, as well as auditory and visual hallucinations.

Schizophrenia is being studied with pea-sized 'mini-brains'

Brain organoid research is enabling researchers to study distinct electrical firing patterns associated with schizophrenia. These "mini-brains" that are constructed in the lab from patients' cells could lead to better diagnosis approaches and drug development.

Examining self-diagnosed synesthesia

A growing number of people on social media claim to have a perceptual condition that lets them smell colors, see music, or taste sounds. But do they really?

US FDA recently approved the first new schizophrenia drug in decades

Though other antipsychotics block dopamine receptors, a new drug, Cobenfy, influences dopamine levels via a different pathway—it stimulates a pair of specialized receptors in the brain that control the release of a substance called acetylcholine. This alternative approach may help patients avoid serious side effects like weight gain. (Some users may experience a paywall.)

Government watchdog says nursing homes are inappropriately diagnosing schizophrenia

The Department of Health and Human Services Office of Inspector General said in a March 2026 report that nursing homes are incorrectly diagnosing their residents with schizophrenia to mask the facilities' misuse of antipsychotic medications. The drugs, the report states, are being widely used to make staff members' jobs easier and to keep nursing home quality measures high—since antipsychotic use for schizophrenia wouldn't be counted against the facility. (PDF)

When common sounds become disturbing

Misophonia causes certain sounds to feel violating, triggering a "very visceral kind of experience" filled with extremely unpleasant emotions, including annoyance, anger, and disgust. A 2017 study found that people with misophonia have elevated activity in the brain's anterior insula—a region associated with interoception, emotional processing, and behavioral responses—when exposed to trigger sounds. Ongoing research suggests trigger sound context affects the severity and manifestation of the condition.

How seizures (potentially) alter consciousness

Seizures occur when intense electrical activity floods the brain, prompting significant loss of self-control and a variety of sensory disruptions and hallucinations. Cultures interpret the episodes differently, with many contemporary norms viewing them as negative while others characterize them as intense spiritual occasions. Author Fyodor Dostoyevsky viewed his seizures this way, as well as cultures in Mongolia, some Shamanic indigenous religions, and others.

Hacking the body for a future that didn't happen

Journalist Adi Robertson experimented with one of the most accessible biohacks: magnets. Having a tiny magnet in their right ring finger meant they could sense magnetic fields, attract small metal objects, and more. But magnets weaken over time, eroding this new sense. Such implants do more than offer a new way of interacting with the world, they also pose new complications, such as the inability to get an MRI.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

AI models incorporate a randomness parameter when generating responses to prompts

AI models use this parameter to prevent repeated outputs by sometimes choosing less likely next words during sequential generation. However, this randomness—alongside insufficient data and training—may cause hallucinations of incorrect results.

50 years of research has focused on unraveling the relationship between music and frisson

One insight reveals that musical passages with surprising volume changes or unexpected harmonies and beauty are more likely to trigger frisson, perhaps because they upend listeners' expectations.

Rodent evidence is mounting that dysfunctional mitochondria may be a cause of Parkinson's

Though researchers have long observed mitochondrial malfunction in Parkinson's patients, it has remained unclear whether faulty mitochondria cause the disease or are casualties of it. Rodent research published in 2025 adds further weight to the idea that it's causative.

Interface device implanted into ALS patients restored some of their abilities

Most people with amyotrophic lateral sclerosis, or Lou Gehrig's disease, require assistance with daily life due to loss of motor control. The electrode-coated, stent-like device used motor mapping data and machine learning to translate brain activity into actions.

Historians theorize Vincent Van Gogh suffered from Ménière's disease or epilepsy

A century after researchers suggested he suffered from epilepsy, some researchers in the 1990s began to support an alternate diagnosis: Ménière's disease, since he had suffered from severe, repeated attacks of disabling vertigo. Still, some researchers remain skeptical of the Ménière's diagnosis. One posits that Van Gogh had temporal epilepsy complicated by his absinthe consumption.

Vertigo may be reduced by retraining your brain with visual fixation

In this video podcast neuroscientist Andrew Huberman describes one way to help alleviate dizziness and motion sickness symptoms. He suggests visual anchoring—fixating your vision on a point several feet away and moving closer to it, if possible, or fixating your vision on your extended finger and slowly moving it toward your nose and away again.

Artificial lightning can improve the yield of shiitake mushroom growers

Researchers have found that shockwaves produced from lightning strikes homogenously break internal filaments called hyphae, transitioning the mushrooms from a vegetative growth to a fruiting phase. Repeated minor shocks near mushroom logs mimicked this effect.

How brain cells carry information

At any moment, there is an electrical storm coursing through your body. Discover how chemical reactions create an electric current that drives our responses to everything from hot pans to a mother’s caress.

The perception of haunted places is influenced by psychology, setting and suggestion

Gothic architecture and tragic histories contribute to the perception of hauntings. Infrasound and black mold can cause experiences reminiscent of paranormal phenomena. Although paranormal investigators use technology to seek natural explanations, many paranormal experiences remain non-falsifiable.

Multiple sclerosis means 'many scars'

That's a reference to the scarring or lesions that occur in the brain, spinal cord, and elsewhere whenever the immune system has a flare-up. The immune system attacks the myelin because it incorrectly responds as if it's a threat, damaging the body's ability to transmit electrical signals effectively from areas of the body to the brain.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Déjà vu is a memory illusion involving brain regions correcting inaccurate memories

Neuroscientists suggest the phenomenon is your brain recognizing that this feeling of familiarity is incorrect, showing off the brain's internal fact-checking system. Younger people experience déjà vu more often because their brains have higher excitatory activity and stronger memory monitoring systems.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

Discover the catastrophic consequences of a failure of the US electrical grid—something that is more likely than many Americans think.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

Fish populations in the Great Barrier Reef have increased after installing waterproof speakers on the ocean floor that played recordings of sounds from healthy coral reefs.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Animal phobias are likely the most common type of phobias, followed by an extreme fear of heights.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

This site reaches millions of visitors who are tired of AI chatbots and seeking human connection. Pretend to be an AI chatbot and ask questions, provide answers, and draw for people in real time.

According to the physics of black holes, our 4D reality may be a hologram—a projection of information coded on a 2D surface on the edge of the universe.

Dirty lightning is a thunderstorm created from friction between rising and falling flows of ash and smoke during volcanic eruptions.

The first horror movie is believed to be George Méliès' 1986 short 'The Haunted Castle,' which pioneered the use of special effects

Graffiti dates back to at least ancient Pompeii, where citizens scrawled messages to one another on public walls

Exploring the Larry Bird punch that almost changed March Madness

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

How Amazon operates a 'flywheel' business model, a self-reinforcing cycle that drives continuous growth