Schizophrenia increases heat death risks in several complex ways

People with schizophrenia typically die 9 years earlier than the general population

The syndrome, which affects roughly 1 in 233 adults, is often associated with other serious health issues, including cardiovascular, metabolic, and infectious diseases, which may contribute to early deaths. The side effects of long-term antipsychotic medications also may influence the mortality timing—weight gain, for example, is a common side effect of the drugs and can contribute to cardiovascular issues.

People with schizophrenia have triple the risk of developing diabetes

It remains contentious if something inherent about the disease or antipsychotics' side effects (weight gain) are mostly to blame. Some newly diagnosed schizophrenia patients already have insulin resistance, raising questions about if patients' brains are getting enough energy from glucose, and if dietary changes—like a high-fat, low-carbohydrate, moderate-protein diet—may help alleviate symptoms.

Heatstroke can reprogram your DNA, putting survivors at risk of future health problems

Severe illness from extreme heat exposure can alter DNA through epigenetics—turning genes "on" or "off" to shape disease risk. These changes can place an organism at greater risk of future health complications—unlike the epigenetic changes produced by moderate, repeated heat exposures.

Traumatic childhood experiences heighten the risk of developing schizophrenia

Clinically termed as "adverse childhood experiences," events such as physical or mental abuse or the death of loved ones have repeatedly been linked to an increase in rates of developing schizophrenia later in life. The reasons behind this link remain under investigation.

Heat-related deaths may have climbed by more than 50% over 20 years

Between 2000 and 2009 one study suggests annual heat deaths averaged around 2,670, but between 2010 and 2020 that figure was likely more than 4,000. Researchers studied 54 million death records from the contiguous US and created mathematical models to arrive at these figures, noting that a combination of aging populations and climate change drove that increase.

Certain medications that affect blood flow or mood boost the risk of heatstroke

Drugs that narrow blood vessels, beta blockers that regulate blood pressure, diuretics, antidepressants, and antipsychotics can all affect the body's ability to regulate its internal body temperature, and so individuals taking these medications need to take special care in extreme heat and when exercising in hot conditions.

Hundreds of vulnerable Chicago residents died in 1995 during a long-lasting heat wave

Eric Klinenberg wrote a book diving into the specifics of the heat wave. His book, detailing the stories and context fueling more than 700 deaths during just one summer week, helps readers understand how social infrastructure lapses, power outages, and ineffective heat responses led to so many deaths.

Most fungal pathogens can't survive the heat of our bodies

Fungal pathogens typically struggle to survive human body temperatures, but researchers hypothesize that global warming conditions will force fungi to adapt to hotter temperatures, with implications for their ability to also survive within our bodies. That type of evolutionary adaptation would lead to more dire health threats for humans.

Misfired motor signals may explain why many people with schizophrenia hear voices

Up to 80% of schizophrenia patients may have auditory hallucinations. Recent research concluded that this symptom may be from misfired motor signals that feed into each other, essentially failing to suppress certain sensory neural activities and that resulting overexcitment fuels hallucinations. The finding suggests that, one day, magnetic pulses might be used to stimulate specific nerves to better regulate the errant signals and reduce or stop hallucinations. (Some users may encounter a paywall.)

People with schizophrenia are excluded from psychedelic research

Individuals with this mental health condition are routinely eliminated from any psychedelic research due to concerns about triggering or worsening psychosis. Yet there is little high-quality research in this area, raising questions about if further research into this question is warranted as interest grows in using psychedelics for therapeutic purposes.

Deinstitutionalization in the 20th century unintentionally led to the incarceration of schizophrenia patients

Activism to shut down problematic asylums in the mid-20th century led to the community release of many patients with severe mental illnesses, including schizophrenia, but without adequate support, this deinstitutionalization in the 1960s and 1970s led to a significant increase in patients with schizophrenia ending up in prisons and homeless shelters.

Government watchdog says nursing homes are inappropriately diagnosing schizophrenia

The Department of Health and Human Services Office of Inspector General said in a March 2026 report that nursing homes are incorrectly diagnosing their residents with schizophrenia to mask the facilities' misuse of antipsychotic medications. The drugs, the report states, are being widely used to make staff members' jobs easier and to keep nursing home quality measures high—since antipsychotic use for schizophrenia wouldn't be counted against the facility. (PDF)

How to survive hypothermia

Hypothermia is a deadly risk for those living in cold areas, causing around 1,500 deaths a year in the United States. Stay safe with tips from this article, which cites research papers to help prevent and treat the condition. Take note of the best fabric to wear when cold weather hits—not cotton but wool.

Listen to how gaps in schizophrenia care helped to lead to a murder

Michael Laudor attended Yale, succumbed to schizophrenia, and killed his pregnant fiancée. The podcast, which includes a long but moving interview with Laudor's friend Jonathan Rosen, uses the tragedy to frame how America's approach to severe mental illness has fallen short.

Extreme weather conditions heighten cholera risks in settings like refugee camps

Runoff from sewage—exacerbated by situations like flooding or extreme rains—heightens this threat. Increasing temperatures also create the ideal conditions for the bacteria to reproduce, increasing transmission risks.

Heart attack risk jumps to 21 times its norm on the day of a loved one's death

Research published in 2012 suggests that the intense emotional burden of suffering a loved one's death can escalate heart rate, blood pressure, and clot risks—culminating in elevated heart attack risk. The increased heart attack risk remains after that first day, remaining eight times above normal during the first week, and then dropping down over the course of a month. (Some users may encounter a paywall.)

Sepsis is the leading cause of death in hospitals

Sepsis is the result of an overly aggressive immune system trying to combat infection, triggering inflammation throughout the body. After it begins, each passing hour increases the risk of death by 4% to 9%, and an estimated 350,000 people die from the condition in the US each year.

Chimpanzees are dying from human colds

For some great apes, the threat of human-borne diseases outweighs poaching or habitat loss. This article details the danger of reverse zoonoses, which refers to diseases that spread from humans to animals.

10 percent of SAD cases occur in the summer

Despite its significantly lower incidence, summer-risk SAD is as significant as its winter counterpart. Rather than being prompted by less light, the summer version is typically spurred by high temperatures, strong light, distinct summer time social pressures (appearing in a bathing suit, for example), and pollen. Common treatments include keeping cool and prioritizing sleep.

Brain activity goes into overdrive around the point of death

Recent studies suggest increased electrical activity in the brain during and after clinical death could be responsible for near-death experiences. Both high-frequency gamma waves (linked to perception and attention) and low-frequency beta waves (related to focus and concentration) increased and became more synchronized across multiple brain regions, potentially resulting in a near-death state of heightened consciousness.

Understanding why the thermosphere feels cold, despite exceeding 2,000 degrees Celsius

High-energy solar radiation can raise temperatures above 2,000 degrees Celsius (3,632 degrees Fahrenheit), but the air density in this layer is so low that there would be insufficient collisions between energized molecules and a person's skin to cause them to experience this warmth. Variations in the level of solar radiation reaching the layer cause it to swell and shrink.

What it's like to live with insomnia

The biological process Shakespeare referred to as the chief nourisher of life's feast is necessary for the body and mind to rest and repair from the activities of daily life. As sleep evades the exhausted, sufferers also lose emotional stability, mental clarity, social connections, and more while simultaneously gaining waves of interrupted biological processes that can lead to disease and death.

Links between long-term caregiving and chronic stress

This Cleveland Clinic overview suggests that around 60% of people caring for family or loved ones with health conditions will experience burnout. Caregivers prepare meals, help with transportation, administer medications, and perform daily tasks for others, all while managing their own lives. This guide may help readers overcome the guilt or frustration of long-term caregiving to seek alternative options.

Shingles vaccine may slow biological aging in older adults

Research published in 2025 that analyzed data from thousands of older adults found that those who had received the shingles vaccine exhibited signs of slower biological aging, such as lower levels of inflammation and slower epigenetic aging, than those who had not been vaccinated.

Home energy performance can be boosted through home orientation and shading

When designing a home, placing living areas to the north maximizes sun exposure during winter, while eaves and awnings can limit excessive summer heat. Breezeways and entry air locks can also reduce the dependence on heating and cooling costs.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

11 people died from firework injuries in the US in 2024.

Poison ivy will likely become both larger and more resilient due to climate change.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Human-to-human transmission of hantavirus remains extremely rare, so the 2026 hantavirus cruise ship outbreak doesn't mean we're facing a COVID-style pandemic risk.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

The boiling temperature of water decreases with increasing elevation because the molecules need less energy to overcome the lower atmospheric pressure associated with thinner air.

About 12.5% of US adults experience a phobia in their lifetime, a diagnosis that hinges on the intense fear interfering with daily life and persisting for at least six months.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

The deadliest aspect of volcanic eruptions is often not lava, but pyroclastic flows—avalanches of ash, gas, and rock that can move more than half the speed of sound.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Existentialist writer Jean-Paul Sartre coined the famous phrase 'Hell is—other people' in his play 'No Exit'

Massive 3D printers have been used to build homes by stacking layers of 'concrete toothpaste,' a fire-resistant material that effectively insulates against outside noise.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

Cultural norms about how to handle the bodies of loved ones in communities in West Africa have hampered Ebola responses.

Some renewable energy sources may weaken the resiliency of electric grids by removing outage buffers provided by coal- and natural gas-fired plants, which provide the system with more time to find a new power source if a plant goes down.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

Chaos theory—informally known as the butterfly effect—is the reason why weather forecasts are presented with probabilities rather than certainties.

Before writing 'Walden,' transcendentalist Henry David Thoreau nearly burned down his hometown with a campfire that grew out of control.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.