80% of schizophrenia cases may be inherited

Less than 1% of people globally have schizophrenia, a syndrome strongly linked to genetics

Schizophrenia's causes remain largely unknown, though scientists suggest it's caused by multiple factors. Its symptoms include disruption of thought processes rather than the exhibiting of multiple personalities. This brief video provides an overview of the condition.

Some data links schizophrenia to older paternal age and birth complications

Yet both associations are not yet considered firm enough to definitively be causative. Schizophrenia is a multi-causal syndrome and a mixture of factors, including genetics, are widely believed to be behind its development.

People with schizophrenia have triple the risk of developing diabetes

It remains contentious if something inherent about the disease or antipsychotics' side effects (weight gain) are mostly to blame. Some newly diagnosed schizophrenia patients already have insulin resistance, raising questions about if patients' brains are getting enough energy from glucose, and if dietary changes—like a high-fat, low-carbohydrate, moderate-protein diet—may help alleviate symptoms.

Traumatic childhood experiences heighten the risk of developing schizophrenia

Clinically termed as "adverse childhood experiences," events such as physical or mental abuse or the death of loved ones have repeatedly been linked to an increase in rates of developing schizophrenia later in life. The reasons behind this link remain under investigation.

Schizophrenia symptoms, like psychosis, often first emerge among young adults

A combination of genetics, significant brain changes to the frontal cortex, and hormonal changes during young adulthood—late teens to early 30s—result in schizophrenic symptoms often showing up during this period. The stress of life changes at that age may also be a contributing factor.

The sibling of someone with autism has a 20% chance of developing ASD

The disorder is strongly linked with inheritance, and research suggests that if one child has ASD, there's a one in 5 chance the next child will develop autism, which is seven times more likely than the general population.

Gene expression patterns are similar between ASD, schizophrenia, and bipolar disorder

Postmortem brain tissue analysis suggests there are genetic and epigenetic similarities between individuals with autism, schizophrenia and bipolar disorder. All three conditions appeared to have activation of genes in astrocytes and suppression of specific genes that function at the junction between neurons, called synapses. (Some users may encounter a paywall.)

Twin studies suggest celiac disease is among the more genetically-linked disorders

Genetics appear to play a larger part in this condition's development than many other autoimmune disorders. Research shows a roughly 60-75% genetic probability that if one identical twin has it, the other will too. Celiac triggers a small intestine attack when people eat gluten, a protein commonly found in wheat, barley, and rye.

Common genetic disorders

As research continues, it's clear that disease and genetics go hand in hand. Here's a selection of 50 National Human Genome Research Institute (NHGRI) articles providing basic information on genetic, orphan, and rare diseases caused by mutations in DNA sequences, whether inherited from parents or brought about by outside factors.

People with schizophrenia are excluded from psychedelic research

Individuals with this mental health condition are routinely eliminated from any psychedelic research due to concerns about triggering or worsening psychosis. Yet there is little high-quality research in this area, raising questions about if further research into this question is warranted as interest grows in using psychedelics for therapeutic purposes.

Schizophrenia is challenging to diagnose and treat

The disorder is diagnosed by a clinician who observes behaviors and medical history and may run additional tests to rule out other explanations for symptoms including physical injury or other mental health disorders. But, ultimately, it's largely a diagnosis of exclusion—since there is no definitive test for the disease. Antipsychotic medications can help control its symptoms for some patients, but there is no cure for schizophrenia.

Misfired motor signals may explain why many people with schizophrenia hear voices

Up to 80% of schizophrenia patients may have auditory hallucinations. Recent research concluded that this symptom may be from misfired motor signals that feed into each other, essentially failing to suppress certain sensory neural activities and that resulting overexcitment fuels hallucinations. The finding suggests that, one day, magnetic pulses might be used to stimulate specific nerves to better regulate the errant signals and reduce or stop hallucinations. (Some users may encounter a paywall.)

Many cancers arise from genetic mutations inherited from your parents

These mutations may happen in response to environmental or lifestyle factors, or may be passed down through family members. Genetic testing can be important in catching certain family cancers early and ensuring patients receive the right treatment for their disease.

Almost 80% of people diagnosed with autoimmune diseases are women

Yet it's still unanswered what may account for that difference. To better understand this disparity researchers are exploring factors including hormonal changes that occur around puberty, pregnancy, and menopause, as well as gut microbe differences, and aspects of X-chromosome protein-coding genes. (Some users may encounter a paywall.)

Some dementia cases may be linked to microorganisms in the brain

Researchers now know that, much like the gut, the brain is home to an ecosystem of microorganisms—the brain microbiome. While this area of study is still new, some scientists believe 50% of bacteria-caused dementia cases could be treated. (Some users may encounter a paywall.)

Nature versus nurture: Are you the result of your genes or your environment?

Dr. Nancy Segal breaks down how research on twins has revealed just how much our genes influence our behavior and traits—but insists they aren't everything. Catch up on the latest in the nature versus nurture debate.

Half of human DNA is inherited from each parent

Within most cells reside 23 pairs of chromosomes made of tightly wound DNA, and half of each pair is inherited from each parent. The 23rd pair consists of two X-shaped chromosomes, or one such chromosome paired with a Y chromosome, and determines biological sex.

Some people may be genetically predisposed to loving roller coasters

Recent studies indicate that individuals with higher levels of dopamine may be more prone to thrill-seeking behaviours like riding roller coasters or even doing drugs or shoplifting.

MS risk is shaped by geography, not just genes

Latitude—and related vitamin D exposure—seems to affect MS risk. People who migrate from a high-risk MS latitude (like northern Europe or the northern US) to a lower-risk latitude (like tropical areas) before age 15 tend to adopt the lower risk of their new country—suggesting there's a critical window for environmental exposure.

Listen to how one gene affects Alzheimer's risk

Multiple genes are associated with Alzheimer's risk, but one well-known disease-associated gene is the apolipoprotein E (APOE) gene, which is typically involved in making a protein that helps carry cholesterol and other fats in the bloodstream. Specific variants of this gene are associated with elevated disease risk, though even if someone has two copies of the disease, that doesn't mean they will definitely develop Alzheimer's.

Are you hypnotizable?

What causes some people to genuinely fall under the spell of hypnosis and others not? The technique only appears to work easily on about 10% of people, and a variety of both genetic and psychological factors determines one's susceptibility. Researchers suggest effective hypnosis has more to do with a person's self-control than with external influence—and the technique can have tangible benefits.

Roughly 90% of generational wealth dries up by the third generation, epitomized by the phrase 'shirtsleeves to shirtsleeves in three generations'

Several factors can influence how wealth is passed down from generation to generation, but some of the main threats are mismanagement, estate taxes, and an expanding family tree.

Chagas disease can be transmitted to a fetus during pregnancy

Researchers estimate that 63 to 315 cases of congenital Chagas disease occur annually in the US. Roughly 20 to 30 percent of all Chagas disease cases will progress to cardiac or gastrointestinal disease.

Most people with East Asian ancestry are genetically predisposed to be less smelly

A gene variant found in 80%-95% of individuals with East Asian ancestry reduces armpit bacteria and related odors. People with this nonfunctioning ABCC11 gene variant lack a protein that transports molecules, including sweat, across cellular membranes, so their armpits are starved of sweat that bacteria may have metabolized to help them multiply.

More than a third of America's incarcerated population has a mental illness

Fueled in part by America's deinstitutionalization movement and gaps in mental health support, an estimated 44% of those in jail and 37% of those in prison have a mental illness, according to figures from 2012, the latest available. Population-wide, only 18% of the general population is estimated to have a mental illness.

About 12.5% of US adults experience a phobia in their lifetime, a diagnosis that hinges on the intense fear interfering with daily life and persisting for at least six months.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

US housing costs have risen by roughly 175% between 1991 and 2026—but a growing number of Gen Zers are becoming homeowners anyway. In 2025, 4% of homebuyers were Gen Z, up from 3% the year before.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Use this tool to calculate the dollar value of your parental mental load, from meal planning to coordinating after-school care, then see resources that help generate solutions.

Chaos theory—informally known as the butterfly effect—is the reason why weather forecasts are presented with probabilities rather than certainties.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Poison ivy's rash-causing compound is found in the plant's roots, stem, and leaves—so coming into contact with any part of the plant can lead to rashes for the 85% of people who are allergic to it.

The Nasdaq's 'Magnificent 7' companies are responsible for roughly 40% of the Nasdaq 100 index's gains, while the remaining 93 companies account for the other 60%.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

Despite being favored by 87% of Americans, Congress does not have term limits.

Art theft is the third-largest source of criminal revenues worldwide, thanks in part to the subjective nature of valuing a work of art.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Domino's Pizza's 30-minute delivery guarantee was responsible for the chain's 1980s surge, but it was discontinued after the company was found liable for delivery driver accidents.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

'Shogun,' a 1980s TV series, helped popularize sushi in the US by stimulating an American interest in Japanese culture.

The Brothers Grimm were lawyers before they were storytellers, but became interested in fairy tales as they began investigating how rules and customs had been passed down through cultures.

The 1987 Nintendo video game 'Stadium Events' isn't known for being particularly fun, but its scarcity has made it a highly sought-after item that has sold for up to $35K at auction.