Multiple sclerosis means 'many scars'

There are multiple types of multiple sclerosis—they differ by attack patterns

When your immune system targets the nervous system, this can cause new or worsening symptoms and the development of scarring or damage within the central nervous system. Relapsing-remitting MS is the most common type of the disease—it includes progressive bouts of attacks that occur months or years apart.

Sclerosis is the technical term for the lesions or plaques that form without myelin

In the absence of myelin, the body forms scar tissue called sclerosis. That scar tissue hampers nerve's abilities to transmit nerve impulses, essentially acting as a roadblock to speedy communication.

MS can damage the brain up to 7 years before symptoms appear

Recent research scouring blood samples from 134 people with MS, both before and after their diagnosis, found that about seven years before these patients were diagnosed, there was a spike in a protein called myelin oligodendrocyte glycoprotein—indicating disease-associated damage to the protective myelin around nerve fibers.

How autoimmune diseases, which attack your own tissues and cells, work in the body

These diseases remain some of medicine's thorniest problems because the immune system can mistakenly attack almost any tissue in the body, resulting in myriad diseases, including lupus (numerous tissues affected), Hashimoto's (thyroid), and MS (the nervous system).

Changes in vision or eye pain can be early MS symptoms

This occurs due to myelin degradation around the optic nerve, impairing its ability to transmit visual information to the brain. Individuals may especially experience eye symptoms after exercising or taking a hot shower because boosted body temperatures slow down nerve function in nerves already damaged by MS.

How MS is diagnosed with brain and spinal cord MRIs and eye tests

There's no definitive test for MS, but to make a diagnosis doctors typically use MRIs of the brain and spinal cord to hunt for telltale lesions. Also, optic nerve tests to see how quickly information travels down the optic nerve—since degraded myelin sheaths will slow electrical signals between the eye and brain.

Schizophrenia literally means 'split mind'—a reference to patients' break with reality

Contrary to the name, patients do not have multiple personalities. Rather, the split mind refers to the sufferers' inability to distinguish reality from hallucinations when they are aware and awake. Cognitive difficulties, including challenges focusing and communicating are also common among those with schizophrenia, as well as auditory and visual hallucinations.

Secondary complications from measles in children range across the whole body

The most serious effects of a measles infection, particularly in young children, come from its attack on the immune system. This leaves the whole body vulnerable to follow-on diseases, with some of the most serious including respiratory conditions, encephalitis, and more.

MS risk is shaped by geography, not just genes

Latitude—and related vitamin D exposure—seems to affect MS risk. People who migrate from a high-risk MS latitude (like northern Europe or the northern US) to a lower-risk latitude (like tropical areas) before age 15 tend to adopt the lower risk of their new country—suggesting there's a critical window for environmental exposure.

Lupus, an autoimmune disease with varied symptoms, was named for wolf bite-like lesions

The 13th-century physician behind the name (lupus is Latin for wolf) named it after a patient he saw who had facial lesions that looked to him like a wolf's bite. Other common symptoms of the disease include extreme fatigue, painful and swollen joints, fevers, and light sensitivity.

Remylination is a huge focus for treatment—especially among older adults

Our ability to build new myelin sheaths for nerves degrades with age. There have been research advances boosting cells that support these processes and clear away debris from degraded myelin, but not yet any medications to boost myelination itself, which would aid nerve signaling and preserve nerve function.

What happens to the brain during migraine?

Migraine is a neurological condition that can cause debilitating symptoms across various bodily functions. So, what exactly is happening in the brain during these attacks? This five-minute video briefly overviews the internal machinations behind the painful episodes. An incapacitating headache is a common symptom of migraine, though migraine can occur without any headache.

Scleroderma, which causes skin to harden and scar, has no FDA-approved treatment

It's an autoimmune disease that disproportionately causes worse complications in African American people for unknown reasons. It causes the body to overproduce collagen after the immune system attacks the body's own connective tissue, leading to excess collagen deposits and restricted blood circulation as small blood vessels are damaged. It can damage various organs, including the lungs.

Long-term memory issues among West Nile survivors may be from immune response, not virus

Rodent research suggests that long-term neurological complications such as fatigue, weakness, difficulty walking, and memory loss, may be due to the immune system systematically destroying parts of neurons in the brain in response to the infection, rather than due to viral infection itself.

How supplements and alternative medicine are being used to treat MS

MS patients often use complementary and alternative medicine approaches for MS, including acupuncture, yoga, specific diets, herbs like turmeric, and cannabis. Information on integrative approaches often come from support groups and online communities. Complementary care is typically used in conjunction with traditional medicines.

Metastasis: When cancer cells begin to travel through the body

Metastatic cancer starts in one part of the body and moves to another over time. This is known as metastasis. Such cancers are much more harmful since they attack multiple parts of the body, adapting new metabolic changes to suit the various environments found throughout a body.

How trauma gets ‘under the skin’

A study examining the muscle function of older adults who have at least one adverse childhood experience (ACE) suggests that trauma digs itself into muscle cells. Participants who reported childhood trauma were found to have lower maximum levels of cellular energy than people who reported fewer or no ACEs. Such compromised mitochondrial function "doesn't bode well," as it relates to a variety of health and age-related outcomes.

Misophonia is a neurological disorder where sounds trigger strong emotions

The phenomenon is characterized by decreased tolerance to specific sounds, such as heavy breathing, pen clicking, and water dripping, which trigger a fight-or-flight response. The resulting emotions, which can range from irritation and disgust to anxiety and fear, can be overwhelming and uncontrollable.

The immune system fights tattoos

Our skin is a fascinating organ that wants nothing more than to protect our bodies from the outside world. Tattoos penetrate that protective wall to inject ink directly into the sensitive, immunologically rich layer of skin known as the dermis.

Myokines are molecules that facilitate some of the benefits of exercise

When muscles contract, they release ‘hope molecules’ (myokines) such as IL-6 and irisin. These proteins then travel through the bloodstream to reduce inflammation, improve insulin sensitivity, and even support brain repair. This piece illustrates how movement triggers a systemic healing cascade throughout the human body.

Actresses Christina Applegate and Jamie-Lynn Sigler describe MS ignorance and stigma

Applegate discusses with Conan O'Brien how ignorance about the disease and fake cure information continue to proliferate. Sigler, known for her role on HBO's Sopranos, also discusses how she is now prioritizing roles that will have a disability, like her.

Engrams are the specific pattern of brain cells that make up a memory

Memory isn’t stored in your brain in a neat little package but is instead spread across a pattern of cells in different regions. Understanding this process could lead to better treatments for conditions like Alzheimer’s or PTSD.

Tattoos remain visible on your skin thanks to immune cells called macrophages

Malaria comes from the Italian term 'mal'aria,' meaning 'bad air'

The term refers to marshy areas associated with the disease. An estimated 94% of malaria cases—215 million—occur in Africa.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

The macula is a small area in the center of the retina

This part of the eye—roughly the bullseye of the back of the eye—is responsible for processing the central vision of the eye. Degradation of the macula, formally called macular degeneration, leads to symptoms including blurred vision, the need for brighter lighting, and difficulty recognizing faces. The condition doesn't affect peripheral vision, but if you lose central vision, you can still be considered blind.

Symmetric patterns of magnetic stripes seen on either side of mid-ocean ridges

The symmetry provides evidence of seafloor spreading, where new oceanic crust is created at mid-ocean ridges, which pushes older ocean crust away on either side. Matching the pattern to magnetized material in rocks on Earth’s surface provided a timeline of ocean floor recycling.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Fear or disgust related to clusters of holes and cracks, called trypophobia, may stem from evolutionary processes to help us avoid pathogens.

Ebola is a filovirus, meaning it resembles a thread under a microscope, though it sometimes twists and can resemble a bowl of spaghetti.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Firework or sparkler burns, even if they cover a relatively small area of skin, can significantly affect our range of motion.

Poison ivy's characteristic rash is caused by an allergic response to an oily compound in the plant called urushiol.

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

Browse a detailed visual analysis of over 200,000 similes—comparisons that often use 'like' or 'as'—from popular fiction to see how frequently writers the same idiomatic expressions.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

An investigation suggests a Scottish island became awash in forever chemicals via seafoam and seaspray—raising questions about what that means for the safety of other coastal areas.

In 2019, a laptop loaded with six of the worst malware in history and described as 'an exhibit of historical weaponry' sold for $1.3M.

Power lines are dotted with large, brightly colored balls to improve the visibility of these thin wires to helicopters and small planes and help prevent potential crashes.

Volcanoes 'die' when their supply of magma runs out, if they are shifted away from their underlying magma reservoir, or if they get clogged by collapsing or their magma cooling back into rock.

Chaos theory—informally known as the butterfly effect—is the reason why weather forecasts are presented with probabilities rather than certainties.

See 33 images that became central to huge scandals, including a young Charles and Camilla, Michael Jackson's baby on a hotel balcony, and Hugh Grant's mugshot.

Some renewable energy sources may weaken the resiliency of electric grids by removing outage buffers provided by coal- and natural gas-fired plants, which provide the system with more time to find a new power source if a plant goes down.

Some coin denominations have ridges etched on their sides, partly to prevent counterfeiting, in a practice called 'reeding.'

Search a massive database of over 4 decades of clues from the TV quiz show 'Jeopardy!'

Existentialist writer Jean-Paul Sartre coined the famous phrase 'Hell is—other people' in his play 'No Exit'

'Grand Canyon of the Yellowstone,' a work by American painter Thomas Moran, inspired Congress to establish Yellowstone National Park.

The word 'jazz' evolved from 'jasm,' 19th-century American slang for 'energy'