Myokines are molecules that facilitate some of the benefits of exercise

Complex molecular reactions in our tissues cause muscle contraction

When we want to move a muscle, a signal travels from the brain and into the muscle cells in question, sparking a chemical reaction that causes the muscle's smallest contractile units—sarcomeres—to shorten, forcing the muscle to contract.

The reason some people love exercise may be because of their microbiome

Certain gut microbes in mice trigger dopamine release and drive motivation to exercise more. Scientists are investigating whether humans carry similar microbial patterns that influence our natural inclination towards movement, exploring how unseen microbial ecosystems may shape mammalian fitness behavior and reinforce innate reward pathways. (Some users may experience a paywall.)

Optimal human functioning requires movement

There is now ample evidence to back the centuries-old hypothesis that exercise is critical to human health. This review article explores the latest discoveries in exercise science, including how exercise is intrinsic to maintaining our organ systems throughout life.

Exercise releases chemicals that enhance cognitive function

Neurotransmitters like dopamine, serotonin, and norepinephrine, along with increased brain-derived neurotrophic factor levels, enhance a wide range of brain functions. New research demonstrates a direct link between movement and numerous cognitive benefits, including memory, learning, and stress resilience.

Exercise changes your genes without changing your DNA

Physical activity can turn beneficial genes on and harmful genes off, without altering the underlying DNA code. This engaging article explains the epigenetic mechanisms that take place with exercise and ultimately result in improved metabolism, lower inflammation, and optimized brain function.

Microtears in muscles from exercise cause fibers to grow back larger

Placing muscle under increased load or stress causes damage that requires rest to repair, leading to stronger, more enduring muscle over time. Muscles adapt to such increasing demands by improving their efficiency with approaches that include increasing the number of mitochondria housed in hundreds of thousands of muscle cells.

Muscles fatigue due to the loss of energy like ATP and glycogen

Adenosine triphosphate fuels muscle contraction, and with each contraction (like during exercise), the amount of ATP reduces. ATP helps potassium and sodium move across muscle membranes, generating ions and helping to contract the muscle.

Exercise helps make your arteries more elastic

Regular aerobic exercise releases nitric oxide, a key molecule that relaxes blood vessel walls and improves vascular function. These exercise-induced adaptations make the heart work more efficiently and blood vessels become more elastic, leading to improved circulation and lowered cardiovascular risk.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Peptide TB-500, promoted for regenerative healing, is not FDA approved

Watch a board-certified sports medicine therapist detail his thinking about this synthetic peptide; he says it's "promising but unproven." He notes that this product is designed to mimic the natural protein thymosin beta-4, found in human and animal tissues, which promotes wound healing. TB-500 is classified as a research peptide for recovery, meaning it's not approved for human use and has not yet undergone rigorous human trials on its safety and efficacy.

Can microdosing improve mental health?

Animal studies involving microdoses of psilocybin, the psychoactive component in magic mushrooms and ketamine, found it helped to alleviate anxiety and inflammation, an immune response that can cause damage when chronically active. Human studies are ongoing. In at least one double-blind study, where researchers and patients don't know who got a placebo versus the real thing, about half of the participants incorrectly guessed they had been given placebos.

How the body produces its own opioids

Opioids act on the body's own opioid receptor system. The endogenous opioid system comprises four molecule receptor types found throughout the body. When activated, these receptor types trigger the release of dopamine and suppression of noradrenaline, neurotransmitters, respectively, associated with reward and alertness. This opioid system helps regulate emotions, and its disruption is linked to neuropsychiatric conditions, including depression, PTSD, and Alzheimer's disease.

Inflammaging is chronic low-level inflammation as we age, and it may be a key disease driver

The term refers to the idea that largely invisible but consistent low-level inflammation as humans age fuels chronic diseases and cellular aging. Inflammaging, this article says, is due to lifestyle factors like poor sleep, low levels of activity, and poor diet, acting in concert to cause cellular damage and trigger inflammation.

Goose bumps may play a role in hair growth

Research in mice suggests that the same muscles that contract to create goose bumps act as the bridge for the sympathetic nervous system’s connection to hair follicle stem cells. This raises questions about how this knowledge could be used to reactivate the sympathetic nerves in hair follicles to boost hair growth in people.

What do vitamins actually do?

Vitamins are molecular tools the body needs to carry out regular cellular processes, such as wound healing. This 45-minute video dives into the science behind vitamins and their role in the body. There are 13 essential vitamins that must be...

Research suggests Ozempic has benefits beyond weight loss

Semaglutide, the key ingredient in Ozempic, is proving to be more than just a diabetes and weight loss drug. Research suggests it may also help prevent strokes, improve heart health, and slow Alzheimer’s.

Positive role models are a benefit of support groups

Meeting individuals who are going through similar life experiences or navigating similar health journeys can provide inspiration and be a benefit of attending in-person or online support groups.

Snake venoms are repurposed proteins responsible for other bodily functions

Just as saliva aids digestion in humans, proteins responsible for bioactivities such as digestion and blood clotting were eventually secreted in the glands and fangs of snakes across evolutionary history. Organisms that could not withstand the effects of these molecules (e.g., excessive bloodstream clotting) became ideal prey for snakes.

How medical robots could cure cancer

Medical robots are on the verge of being able to be injected into the body, where they will be responsible for semi-autonomous behavior, such as detecting cancer cells and distributing medication. This six-minute video dives into the science of these nanorobots, which are smaller than blood cells. Applications of these nanobots could range from disease discovery and condition monitoring to tissue repair and artificial blood delivery.

Understanding insulin

Scientists Daniel and Kelly talk with researcher Dr. Katrine Whiteson about diabetes, the history of insulin production, and Dr. Lydia Villa-Komaroff—an essential member of the team who discovered that bacteria could be induced to produce insulin. Listen to discover interesting facts about the life-saving medicine and how it works in the human body.

Multiple sclerosis means 'many scars'

That's a reference to the scarring or lesions that occur in the brain, spinal cord, and elsewhere whenever the immune system has a flare-up. The immune system attacks the myelin because it incorrectly responds as if it's a threat, damaging the body's ability to transmit electrical signals effectively from areas of the body to the brain.

A macrophage can eat 100 bacteria, on average, before it's exhausted

These specialized immune cells are first responders during inflammation, responding to a threat or injury and then performing other inflammatory response tasks, including summoning neutrophils to help attack invaders.

The anatomy of 'Mashle,' as described by a doctor

"Mashle: Magic and Muscles" is a manga and anime in which a seemingly magicless man performs outsized feats he blames on "muscle magic." In this 15-minute video, a doctor breaks down the anatomy and biomechanics of some of the feats performed by Mash, the series' main character who's spotted flying a broom via leg pumping and reading magical texts while sitting in an invisible chair (i.e., single-leg squat).

The marvels of mucus

Mucus—otherwise known as snot or phlegm—has a gross reputation, but the substance is actually of vital importance, lining the moist surfaces of our nose, intestines, lungs, and more. It plays a constant role in keeping our tissues from drying out and acts as a line of defense, but if it gets too sticky or thick, it can cause problems. Read about the marvels of mucus here.

Umami synergy—combining glutamates and nucleotides—can amplify a meal

While glutamates are known for triggering the umami taste through specific taste receptors, nucleotides like IMP and GMP can bind alongside glutamates to enhance the receptor's response. This union explains why certain classic food combinations like bacon and eggs taste exceptionally savory.

A visualization of mycoremediation, where fungi extract toxic and radioactive pollutants from soil

As organisms such as mushrooms grow, they develop large networks of root-like structures called mycelium that spread underground and release enzymes that break down contaminants. By absorbing these chemicals, fungi limit the damage caused by these toxins and localize them within the organism for easier collection and disposal.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Tattoos remain visible on your skin thanks to immune cells called macrophages

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

Learn how monoclonal antibodies, which mimic the body's antibodies, can fight diseases like Ebola.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Coral reefs get their colors from zooxanthellae—microorganisms that line corals' digestive tracts and provide them with sugars in exchange for a home within this protective tissue.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Watch how algorithms can be designed to train themselves and self-improve without human input, to the point where the optimized code is too complex for programmers to understand.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.

Volcanoes 'die' when their supply of magma runs out, if they are shifted away from their underlying magma reservoir, or if they get clogged by collapsing or their magma cooling back into rock.

An initial public offering or 'IPO' is the process of a private company becoming public by putting shares of the company on the stock market for purchase.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

See photos of Meteora, a mountainous site in central Greece, home to 14th-century monasteries perched atop soaring outcroppings.

Power lines are dotted with large, brightly colored balls to improve the visibility of these thin wires to helicopters and small planes and help prevent potential crashes.

A small portion of The Winstons' 'Amen, Brother,' an obscure '60s gospel record, is the basis for thousands of hip-hop tracks, making it one of the most sampled records ever that's informally known as 'the Amen break.'

The first robot in literature may have been a 'mechanical man' in 1907's 'Ozma of Oz,' a book in L Frank Baum's 'Wizard of Oz' series.