Optimal human functioning requires movement

Moving your body every day is key to longevity

In an era of biohacking, where millionaires subject themselves to draconian routines and tests to de-age themselves, one study suggests a super simple key predictor of mortality: more than any other trait, how much subjects moved determined how long they'd live. Movement mattered even more than age in predicting overall life longevity. Researchers suggest this means we should all simply get outside a bit more. Read more about the study here.

Exercise improves brain blood flow, stimulates neural growth, and more

Exercise has dramatic effects on human biology, including reducing some of the long-term harms associated with chronic stress. Its effects are also pronounced in the brain, including improved memory retention, sleep, cognitive functioning, and more.

The reason some people love exercise may be because of their microbiome

Certain gut microbes in mice trigger dopamine release and drive motivation to exercise more. Scientists are investigating whether humans carry similar microbial patterns that influence our natural inclination towards movement, exploring how unseen microbial ecosystems may shape mammalian fitness behavior and reinforce innate reward pathways. (Some users may experience a paywall.)

One minute of exercise correlates to five extra minutes of life (on average)

Doctors increasingly view exercise as the single most powerful medical intervention available. Observational studies suggest one minute of exercise correlates to an additional five minutes of life as humans age. Stanford researcher Euan Ashley discusses our current understanding of how exercise provides benefits at the cellular level.

Myokines are molecules that facilitate some of the benefits of exercise

When muscles contract, they release ‘hope molecules’ (myokines) such as IL-6 and irisin. These proteins then travel through the bloodstream to reduce inflammation, improve insulin sensitivity, and even support brain repair. This piece illustrates how movement triggers a systemic healing cascade throughout the human body.

Developing adaptable brain-body systems lets athletes thrive beyond 30

Success in high-level sports after age 30 relies on physical fitness and building brain resilience through deliberate training, recovery, and stress regulation. This creates a feedback loop where body and mind reinforce each other.

Human anatomy 101: the body's systems

Human life is made possible by the body's ten major systems, which maintain homeostasis by responding to incoming sensory and biochemical input. Each system must work independently and collaboratively for the body to maintain health and respond appropriately to its internal and external environments. The bones of the skeletal system, for example, give the body its shape and protect organs while also facilitating movement with the muscular system.

Health officials recommend at least 150 minutes of aerobic exercise per week

This official guideline from the CDC defines the baseline recommendation for healthy adult activity. These recommendations also emphasize that any movement is better than no movement, and that even short bursts of activity spread throughout the week benefit the mind and body.

Healthy adults should perform 'progressive resistance training'

That's the recommendation in March 2026 from the American College of Sports Medicine. They reviewed existing studies on the topic and concluded that resistance training with progressively more weight and repetitions improves muscle strength, size, power, endurance, gait speed, balance, and more.

Astronauts exercise on the International Space Station

Astronauts maintain bone, muscle, and cardiovascular health with physical activity. It's crucial astronauts make time to exercise for approximately two hours per day. This resource offers a behind-the-scenes look at how high-intensity workouts help prevent muscle atrophy, bone density loss, and aerobic decline during months-long space missions.

Activity trackers promise to improve health by forcing us to examine the facts

Explore how modern fitness culture, rooted in capitalist ideals of productivity and control, shapes our perception of health and self-worth. The author blends cultural criticism with personal insight to examine the contradictions of the wellness industry, the rise of wearable tech, and what it means to "optimize" a body.

Studies suggest when you sleep is as important as how much you get

"Molecular clocks" made of timekeeping proteins and genes help regulate the body and its processes, meaning the disruption of one cog will impact another. Those who live in sync with their circadian rhythms report less fatigue, clearer thoughts, greater medication benefits, and better long-term health outcomes.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Modern workplaces were engineered for efficiency, not work-life balance

Modern work organization traces back to 19th-century scientific management, an approach that optimized output by viewing workers as machine components. That logic still persists today and contributes to burnout, stress, and disengagement. Researchers propose a "circular work" model that combines effort with recovery, learning, and renewal, suggesting productivity and well-being should align rather than compete.

Too little stress can be as problematic as too much stress

Hormesis—mild or moderate stress followed by recovery—helps make us more resilient. A stress expert speaking during this roughly 30-minute CNN special explains that our bodies depend on periodic mental and physical challenges to activate our innate defense mechanisms, spurring cellular repair and regeneration.

'Endoevolution' refers to the Darwinian selection happening continually inside us

The term, coined by Roxanne Khamsi in her 2026 book "Beyond Inheritance: Our Ever-Mutating Cells and a New Understanding of Health" describes the idea that evolution does not just occur across generations of humans. Instead, mutated cells continuously compete with healthy ones in our bodies, with implications for our tissues and health. Khamsi says these autocorrections are essentially natural gene therapy. 

Mental health is much more than the absence of mental illness

It's a state of well-being that allows individuals to cope with daily stressors, realize their abilities, learn and work effectively, and contribute to their overall community. Inextricably linked to physical health, modern science indicates that mental health is a central component of our overarching ability to function and enjoy life.

Interest in intermittent fasting outpaces the science

The public interest in fasting diets has outpaced the science behind related health claims. This article details how the science of fasting diets is mainly exploratory and focused on longevity and disease prevention. Current findings suggest fasting kick-starts regenerative processes in the body, decreases inflammation, and improves health outcomes overall. However, much of this research focuses on the short-term impact of fasting.

How to think yourself into health

Can the right thoughts lead to a stronger immune system? Neuroimmunologists like Hai Qi study how drugs targeting the brain, as well as thought exercises, can prompt stronger immune responses to infection. This six-minute video investigates the radical claims.

Ancient Greek gymnasium: where philosophy met fitness

In ancient Greece, gymnasiums were not just places of physical training, but centers of intellectual life. This article explores the ways in which exercise, philosophy, and education were deeply intertwined, reflecting a cultural belief that physical fitness was essential for mental development.

Learn how colorectal cancer is linked to the American diet and chronic inflammation

A University of South Carolina colon cancer researcher offers insights from his own research and notes that more exercise, social support, and eating fruits, vegetables, legumes, and foods like fish and olive oil—often called the Mediterranean diet—are associated with better health—and could improve our colons.

The evidence for the best sleep positions

For a behavior so crucial to human health, sleep positions are reportedly understudied by researchers. This article summarizes some of the more recent studies, taking into account the various forms of problems encountered during sleep: neck and back pain, snoring, acid reflux, and facial skin damage. Most studies point to side-sleeping as the most optimal, with sleeping on one's front as the least helpful. Read the piece to see which position is best for you.

Why don't humans hibernate?

Hibernation is a superpower in the animal world that allows certain species to time travel from difficult times to abundance. This essay in Aeon explains this helpful natural process and why humanity's technological advancements may have hindered our ability to participate in the practice. Learn about the rising interest in human hibernation as a result of modern adversity, and if it could potentially become a reality.

Men and women didn't evolve to perform segregated hunter-gatherer duties

The often-cited theory that men evolved to hunt and women evolved to gather is wrong. This article explores the origins of the "Man the Hunter" theory and the mounting evidence that undermines it. Exercise science indicates that those assigned...

Is metabolism related to weight loss?

Read this article to better understand metabolism and why doctors say it's only one piece in the puzzle to managing weight. Metabolism breaks down and converts what we consume into energy, which provides fuel for all of our body's functions—both...

The science of symmetry | The Royal Society

Nature is full of symmetries, from spiral galaxies to florets of broccoli. So why do complex creatures break the pattern?This short video discusses why symmetry came to dominate life on Earth, and how many complex life forms, such as humans, transitioned from radial to lateral symmetry.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Watch how algorithms can be designed to train themselves and self-improve without human input, to the point where the optimized code is too complex for programmers to understand.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

SpongeBob exemplifies Aristotle's philosophy for living well because he understands that happiness doesn't come from external factors like money, recognition, or power.

Ebola infects and disables immune cells, triggering a cascade of events that leads to small blood clots throughout the body, weakening blood vessels and interrupting blood flow to key organs.

How Amazon operates a 'flywheel' business model, a self-reinforcing cycle that drives continuous growth

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

While the sun's gravity keeps the planets in orbit, their gravity also pulls on the sun, causing it and everything else in the solar system to orbit around a mutual balance point called the barycenter—the true center of the solar system.

The US Constitution is widely regarded as the longest-standing written national constitution still in force—see how it has influenced rights worldwide.

Some researchers have labeled nomophobia, the fear of being without your phone, as 'the phobia of the 21st century.'

Pure water does not conduct electricity because this flow of energy requires the movement of charged particles, and water is a neutral molecule.

Legendary architect Frank Lloyd Wright designed the SC Johnson headquarters in Wisconsin, aiming to make a cathedral-like workplace

Before humans, the Soviet Union and the United States sent animals—including apes, dogs, and cats—to space during the Space Race.

Hedge funds, the private investment firms that trade a wide swath of financial assets, make money by imposing steep fees on investors and from the fund's investment performance.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

The word 'jazz' evolved from 'jasm,' 19th-century American slang for 'energy'