Interest in intermittent fasting outpaces the science

Can fasting help you live longer?

Animal studies into the health benefits of calorie restrictions of 20%-40% suggest it extends life spans and reduces incidents of age-related diseases, including cancer. This article explores the research into fasting, calorie restriction, and longevity.

Multiple new research paths may lead to slowing (or even reversing) aging

Aging has always been inevitable, but fasting, epigenetic reprogramming, and parabiosis seem to help people stay young. By studying centenarians, memory, and even the humble roundworm, scientists are looking for the genetic basis to live not just a long life, but a healthy one.

The stages of fasting

What happens to the body when it goes without caloric intake? This article overviews the immediate physical effects of fasting. Within a day of going without food, the body will have used up its glucose stores and ordered the liver and muscles to convert their glycogen (glucose storage) into usable glucose. By the second day, glycogen stores will run out, forcing the body to use fat as energy. This process is known as ketosis.

Can we speed up our metabolisms?

Listen to this 31-minute podcast to better understand what science knows and doesn't know about metabolism, as well as the only thing that seems capable of changing it. Scientists understand that the difference between a so-called “fast” and “slow” metabolism does not affect one’s ability to lose weight.

How meal timing factors into health outcomes

The world is trending toward weight gain, a development that comes with a corresponding rise in risk for health conditions, including diabetes and heart disease. This article explores how meal timing has become a factor in nutrition and weight maintenance.

History's weirdest weight loss fads, fact-checked

Nothing catches popular attention more than a claim to have found a quick weight-loss technique. History shows us such claims are often unfounded. Dr. Michael Mosley explores extreme weight-loss tips from history, from tapeworms to vinegar diets.

As of 2025, extensive research studies do not support fears about seed oils

Across human trials, seed oils have not been shown to increase rates of disease or inflammation, with a study of over 800 Swedish men finding that higher seed oil diets were linked to living longer. Reviews of these trials found better health outcomes when saturated fats were replaced with seed oils.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Learn the history of food science breakthroughs from the 20th century

Long after humans developed the means to produce sufficient food to feed civilizations, scientific research focused on a wide variety of objectives, such as developing methods to preserve food quality (accomplished via frozen food), speeding up cooking (leading to the microwave), and lowering the cost of sweetening food, which high fructose corn syrup provides.

The strange endurance of consuming blood for health

Blood's importance to humanity is best summarized this way: without it, we die. This importance naturally begets assumptions about its medicinal properties, many of which appear accessible through drinking or eating the fluid connective tissue. This article details the history of blood drinking, from ancient Roman gladiators to modern-day sanguinarians.

Anorexia as religion: from the Middle Ages to modern message boards

Humanity's interest in anorexia nervosa can be traced back to the Middle Ages and the rise of "fasting girls." This article explores the history of the eating disorder as a religion. The first recorded anorexics appeared during the 13th century...

Optimal human functioning requires movement

There is now ample evidence to back the centuries-old hypothesis that exercise is critical to human health. This review article explores the latest discoveries in exercise science, including how exercise is intrinsic to maintaining our organ systems throughout life.

The gaps in menopause research and their effects

Nearly all studies (99%) researching the biology of aging don’t consider menopause in their setup. A Harvard professor noted that about 75% of aging-related diseases are likely influenced by menopause. In this article, she discusses how gaps in research are negatively impacting how the medical system can effectively treat aging women. Read her analysis of the issue here.

The lack of guidance on getting off GLP-1s leaves patients at risk

Dr. David Kessler, former FDA Commissioner and public health leader, explores how these drugs override the brain’s reward-driven eating habits but have notable side effects. These include developing eating disorders, muscle loss, and intestinal obstruction.

At-home genetic testing results commonly led users to healthier lifestyles

Italian research that aimed to investigate what people do longer-term after receiving direct-to-consumer genetic test results indicated that whether the results were positive or negative, people tended to adopt a healthier diet after receiving the results, and they'd still maintained it a year after receiving their results. Some users also reported an overall reduction in stress over their health concerns. (Some users may encounter a paywall.)

The term 'superfood' is a marketing construct with no scientific or medical definition

Encompassing at least 136 plants and animals, the concept has been criticized by nutritionists for its scientific value, which has been exploited by the wellness industry for profit. Although the label has encouraged the consumption of fruits and vegetables, food variety and minimal processing remain key to a healthy diet.

There are no established minimum fitness standards for spaceflight

Microgravity is known to cause arterial hardening, bone weakening, and other health issues, but the novelty of space tourism and the minimal exposure time for suborbital trips have limited the number of research studies. Many companies have participants sign extensive waivers to bypass the requirement of specific medical standards.

Lengthy incubation periods are why it’s tough to link foodborne illness to specific foods

People may not get sick from a foodborne pathogen for several days after consuming it, making it a challenge to link the illness and its cause. Factors influencing when a person starts feeling sick—even as the pathogen is multiplying in the gut—include individual variations in immune systems and gut microbiomes, what other foods are in the person’s body, and how much of the pathogen was consumed.

Why don't humans hibernate?

Hibernation is a superpower in the animal world that allows certain species to time travel from difficult times to abundance. This essay in Aeon explains this helpful natural process and why humanity's technological advancements may have hindered our ability to participate in the practice. Learn about the rising interest in human hibernation as a result of modern adversity, and if it could potentially become a reality.

Read a deep dive on the 'all-purpose healing' peptide BPC-157

The unapproved peptide—which has received glowing testimonials from bodybuilders, biohackers, popular podcasters, and some in the MAHA movement— is often sourced from China. It has been used for myriad conditions. But scientific questions about the substance abound, including whether it's truly a natural substance produced by the human body, since genetic material that codes for its unique amino acid sequence hasn't been found in the human genome or the gut microbiome. Other unknowns include how it works in the body, which receptors it targets, and its safety, since evidence beyond anecdotes remains scant in humans.

Arnold Schwarzenegger fueled a lot of the interest in strength training, beginning in the 1980s

This was notable because clinicians around the 1950s thought that lifting heavy weights was bad for health, dampening muscle-strengthening interest that dates back to the ancient Greeks. Beyond Schwarzenegger-inspired interest and the popularity of Venice Beach bodies, the weight training movement also later gained momentum due to accumulating scientific evidence and the rise of entities like Crossfit. (Some users may experience a paywall.)

How one autoimmune disease patient is questing for inflammation cures

This article's writer, who has Hashimoto's Disease and characteristic symptoms from her body attacking her thyroid—like exhaustion, hair loss, and brain fog—shares big take-aways from an anti-inflammatory retreat in Italy. The writer suggests that a holistic approach to eating, sleeping, and stress management, are the only sustainable ways to lower inflammation.

Reduced inflammation from cold plunges lacks scientific support

The cold water triggers immediate cold shock, increasing heart rate and blood pressure, and prolonged exposure can lead to cold-water incapacitation and hypothermia. Plungers are encouraged to enter the water slowly and manage their breathing to reduce the risk of shock. Warm baths post-plunge are discouraged, and exercise is generally better for recovery.

Nonfiction books have been struggling to sell in the mid-2020s

In the early 2020s, readers sought out nonfiction books to help explain prominent current events, such as the first presidency of Donald Trump and the BLM movement. That interest has since waned, as publishers note that readers have lately shown a preference for escapism and gather their information from podcasts.

Visa data shows Muslim spending spikes at night during Ramadan

Fasting during the day reschedules economic activity to the night. Visa's spending data shows a surge in Muslim-majority markets during Ramadan at night as restaurants and retailers orient themselves around iftar. The pattern has become a significant target for advertisers and brands.

One financial planner says FIRE is a bad idea

Some financial professionals argue that those following the FIRE (financial independence, retire early) movement might be basing their math on too short of a timeline, leaving them without enough money if they live further into old age than expected.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Human-to-human transmission of hantavirus remains extremely rare, so the 2026 hantavirus cruise ship outbreak doesn't mean we're facing a COVID-style pandemic risk.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

How fusion—which releases energy when two lighter atoms combine to form a heavier atom—differs from fission

How the most famous Ebola book, The Hot Zone, which sold 3.5 million copies and was translated into 30 languages, got aspects of the disease so wrong.

SpaceX's S-1 or 'prospectus' revealed many previously unknown details about the company, including its unprofitability despite doing $18.7B in revenue in 2025, exactly how many voting shares Elon Musk will have in the company (roughly 85%), and more.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Hedge funds, the private investment firms that trade a wide swath of financial assets, make money by imposing steep fees on investors and from the fund's investment performance.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.

The US Constitution is widely regarded as the longest-standing written national constitution still in force—see how it has influenced rights worldwide.

In 2026, Finland was named the world's happiest country for the ninth consecutive year based on its wealth, social safety network, and high life expectancy, among other factors.

44% of Americans say they pray at least once a day—discover how your state's religiosity stacks up against the rest of the country.

Discover the catastrophic consequences of a failure of the US electrical grid—something that is more likely than many Americans think.

A 2019 Facebook event called on attendees to "Storm Area 51, They Can't Stop All of Us," resulting in countless memes, the creation of a music festival, and eventually the arrests of those who did try to approach the area.

The Mona Lisa's celebrity status and repeated restorations have obscured what made the painting so revolutionary for its time

'Silent' fireworks have gained more interest in recent years as a quieter celebratory option.

Most of the observable universe's volume consists of voids and supervoids—enormous regions of space with little to no galaxies, stars, or light.