Too little stress can be as problematic as too much stress

Stress evolved as a survival mechanism to keep humans alive

Stress activates the “fight-or-flight” response when we face threats. It’s triggered by the hypothalamus, which signals the release of adrenaline and cortisol, heightening awareness and energy. While acute stress helps in short bursts, chronic stress—persistent over time—can harm both physical and mental health, leading to conditions like hypertension, anxiety, or depression.

The positives of feeling stressed

Worrying about past events and upcoming challenges is not a pleasant experience, but a reasonable amount of stress can bring a lot of good into our lives. In this episode of "The Happiness Lab" with Dr. Laurie Santos, two psychology experts offer tips for resetting one's relationship with stress. Listen and learn how to make stress a positive tool rather than a debilitating emotion.

How we frame stress—as good or bad—seems to alter how it affects us

This podcast discusses research that indicates stress perception may drastically affect how we respond to it. In research exploring if our stress is presented as diminishing our health versus if we're told it enhances our performance, it will lead to differences in how successful participants are at performing tasks—with the enhancers doing better.

The biology of stress in your body

Stress is a normal human response that has evolved over millions of years to handle changes or threats in our environment. This article is a helpful overview of the biological basics of this response. While it is not harmful to our physiology in the acute setting, chronic stress can lead to damaging changes in the human body over many years.

Chronic stress affects nearly all parts of the body

Stress is our body’s internal mechanism to deal with changes in our internal balance. As such, the stress response affects nearly every organ system through a cascade of both fast and slow hormonal changes. While short-term stress can be adaptive, long-term stress may cause serious health issues.

Some types of stress (eustress) have positive benefits

While many perceive stress as solely negative, stress can in fact be divided into two categories: distress (negative stress) and eustress (positive stress). Moderate levels of stress are positive in that they can boost motivation and promote resilience, which have positive mental health benefits.

Stress can be contagious—and scientists want to learn more about it

Researchers have shown that being around someone who is stressed can trigger a stress response in your body, such as elevated cortisol levels and elevated heart rate. One way this was recently studied was by having people watch stressful activities, like a recorded job interview or solving challenging math problems, and then sampling hormones in observers' spit.

Easy resets for stress reduction

Individual solutions for burnout, often called “self-care,” can be helpful for managing stress. Harvard researcher Aditi Nerurkar’s 2024 book The Five Resets details a road map for burnout recovery. In this interview she suggests, among other tactics, gaining focus on what matters the most in one’s life, taking breaks from both work and the internet, and making time for practices that strengthen the mind-body connection.

Just a 10-minute mental health break can yield benefits

The US CDC offers recommendations for alleviating stress in daily life. Short 10-minute breaks can significantly improve mental health, especially when used for activities like deep breathing, dancing, or writing down things you are grateful for. Building meaningful relationships, termed "social connectedness," can also alleviate stress and promote resilience.

How burnout alters your brain

Stress is a normal part of everyday life, and it’s not necessarily all bad. But chronic stress—the kind that leads to burnout—can change the size and functioning of parts of your brain. It can alter the ability to make new brain cells and memories and even potentially modify your DNA.

How do anxiety and stress differ?

This article explains that though “stress” and “anxiety” are often used interchangeably, there are distinct differences between the two. Stress is defined as the body's response to an external trigger and can be classified as acute or chronic. Anxiety, however, tends to be triggered internally by excessive thoughts and judgement. Whereas stress disappears when the trigger is gone, anxiety tends to stick around. If left unchecked, both can escalate into more severe mental health conditions.

Cold water swimming can induce positive stress

The tradition of cold water swimming (or taking a cold plunge, or even a cold shower) has been shown to release the same hormones triggered during a stress response. This can have the effect of increasing blood flow, improved mental acuity, and more.

What employers can do about parental stress

The US Surgeon General recently released a formal warning deeming parental stress a public health issue. The advisory also included recommendations for how employers can mitigate the issue. Employers can help their employees access child care, for instance, or provide flexible working hours. To find out more about what the Surgeon General prescribes, read more here.

Short-term cortisol spikes can boost the immune system

Elevated acute levels can enhance the immune system's ability to fight off infection or respond to injury. Chronic heightened cortisol levels, however, can lead to inflammation that harms cells and tissues over time.

How to build curiosity

Change and uncertainty induce stress, but reframing the unknown into an opportunity for discovery has tangible benefits. Approaching change with curiosity enhances activity in the hippocampus and promotes neuroplasticity, promoting learning and serving as a barrier against anxiety. A neuroscientist explains how embracing the unknown, trying small experiments, and other techniques build curiosity.

Even brief physical activity can trigger the release of neurotransmitters that provide mental health boosts

A couple of minutes of light walking or stretching can increase feelings of energy and reduce fatigue, not just through the release of endorphins. Exercise can also provide self-regulation and improve task engagement and focus in those with certain mental health disorders, like ADHD.

Developing adaptable brain-body systems lets athletes thrive beyond 30

Success in high-level sports after age 30 relies on physical fitness and building brain resilience through deliberate training, recovery, and stress regulation. This creates a feedback loop where body and mind reinforce each other.

Mental health is much more than the absence of mental illness

It's a state of well-being that allows individuals to cope with daily stressors, realize their abilities, learn and work effectively, and contribute to their overall community. Inextricably linked to physical health, modern science indicates that mental health is a central component of our overarching ability to function and enjoy life.

Touch helps newborns regulate stress, gain weight, and feel less pain

Conclusions from this 2024 analysis from a team of Danish researchers included that touch interventions were particularly useful for newborns in regulating cortisol levels, helping newborns gain weight, and reducing pain. (Some users may experience a paywall.)

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

The science of spring fever

Researchers have confirmed what people have sensed for ages: Our emotions during the springtime can go a little wild. This piece breaks down the impact of the seasonal transition on our bodies and prescribes a few ways to mitigate the effects.

Studies suggest when you sleep is as important as how much you get

"Molecular clocks" made of timekeeping proteins and genes help regulate the body and its processes, meaning the disruption of one cog will impact another. Those who live in sync with their circadian rhythms report less fatigue, clearer thoughts, greater medication benefits, and better long-term health outcomes.

How to think yourself into health

Can the right thoughts lead to a stronger immune system? Neuroimmunologists like Hai Qi study how drugs targeting the brain, as well as thought exercises, can prompt stronger immune responses to infection. This six-minute video investigates the radical claims.

Eating competitions can ruin a stomach's elasticity

Competitive eaters make room for all that food by toying with the stomach's ability to expand and contract. Still, doctors warn that repeated stress can destroy that ability, leading to further issues.

Myokines are molecules that facilitate some of the benefits of exercise

When muscles contract, they release ‘hope molecules’ (myokines) such as IL-6 and irisin. These proteins then travel through the bloodstream to reduce inflammation, improve insulin sensitivity, and even support brain repair. This piece illustrates how movement triggers a systemic healing cascade throughout the human body.

Estrogen is a really important hormone for men, too

Many people may be familiar with the idea that too much estrogen can cause infertility and other complications, including erectile dysfunction, but too little estrogen is also a significant medical concern because it can result in a reduced sex drive and limit overall growth.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

Use this tool to calculate the dollar value of your parental mental load, from meal planning to coordinating after-school care, then see resources that help generate solutions.

Human-to-human transmission of hantavirus remains extremely rare, so the 2026 hantavirus cruise ship outbreak doesn't mean we're facing a COVID-style pandemic risk.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

Some renewable energy sources may weaken the resiliency of electric grids by removing outage buffers provided by coal- and natural gas-fired plants, which provide the system with more time to find a new power source if a plant goes down.

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

Chaos theory—informally known as the butterfly effect—is the reason why weather forecasts are presented with probabilities rather than certainties.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Coral reefs get their colors from zooxanthellae—microorganisms that line corals' digestive tracts and provide them with sugars in exchange for a home within this protective tissue.

In 1984, Operation Smash Hit intentionally crashed a 239-ton train into a nuclear waste canister at 100 miles per hour to prove the canister's safety, which remained completely intact and lost just 0.29 of its 100 pounds of pressure.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

How the most famous Ebola book, The Hot Zone, which sold 3.5 million copies and was translated into 30 languages, got aspects of the disease so wrong.

The first steps to rebuilding your credit score include getting to know exactly what's on your credit report and figuring out how far you are from the '700 club,' or 'good score' range.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.

The United States has had a tumultuous relationship with Cuba since its 1959 revolution, highlighted by a nuclear crisis and a decades-long trade embargo.

Hedge funds, the private investment firms that trade a wide swath of financial assets, make money by imposing steep fees on investors and from the fund's investment performance.

NBA superstar Victor Wembanyama spent the 2025 summer training with monks in central China to enhance his body and mind.