Stress evolved as a survival mechanism to keep humans alive

Why does the body have a stress response?

When encountering a stressful situation, the human body typically goes into what is known as "fight-or-flight" mode. Because it evolved as a survival mechanism, the biochemical response enables people and other mammals to react quickly to life-threatening situations. The carefully orchestrated yet near-instantaneous sequence of hormonal changes and physiological responses helps someone to fight the threat off or flee to safety.

Our ancient fight-or-flight response may contribute to modern ailments

Many common modern diseases humans struggle with may in fact have their origins in our ancient fight-or-flight stress response. Long-term effects of the stress hormones cortisol and adrenaline—in this case, triggered by things like workplace stressors—can wreak havoc on the delicate internal balance of our organ systems.

The biology of stress in your body

Stress is a normal human response that has evolved over millions of years to handle changes or threats in our environment. This article is a helpful overview of the biological basics of this response. While it is not harmful to our physiology in the acute setting, chronic stress can lead to damaging changes in the human body over many years.

Stress-induced adrenaline can trigger a 'hysterical strength' response

The stress response is a powerful ancient mechanism designed to maximize human survival—it can even result in superhuman strength. The adrenal glands are located just above the kidneys, and stress-induced adrenaline release causes more blood (and therefore more oxygen) to flow to your muscles, increasing performance.

Chronic stress affects nearly all parts of the body

Stress is our body’s internal mechanism to deal with changes in our internal balance. As such, the stress response affects nearly every organ system through a cascade of both fast and slow hormonal changes. While short-term stress can be adaptive, long-term stress may cause serious health issues.

Stress and the brain

While an acute stress response is a normal bodily function, the effects of chronic stress can be extremely damaging to the human body. This is particularly true with regard to the brain. This article explores the effects of stress on the human brain, including how chronic stress may lead to psychological conditions such as depression and memory loss.

Too little stress can be as problematic as too much stress

Hormesis—mild or moderate stress followed by recovery—helps make us more resilient. A stress expert speaking during this roughly 30-minute CNN special explains that our bodies depend on periodic mental and physical challenges to activate our innate defense mechanisms, spurring cellular repair and regeneration.

Stress can be contagious—and scientists want to learn more about it

Researchers have shown that being around someone who is stressed can trigger a stress response in your body, such as elevated cortisol levels and elevated heart rate. One way this was recently studied was by having people watch stressful activities, like a recorded job interview or solving challenging math problems, and then sampling hormones in observers' spit.

The second phase of acute stress: the 'slow' response

The body's reaction to acute stress involves two responses: fast and slow. The first occurs immediately, with the central nervous system triggering the release of adrenaline. The second releases cortisol, which elevates blood sugar and blood pressure and restricts nonessential functions like digestion and the immune system.

Stress is a response to external triggers, while anxiety is persistent and internal

When distinguishing the two, stress is a reaction to identifiable situations like deadlines or conflicts, and its symptoms fade when the stressor is gone. However, anxiety may jump from one worry to another over time without any apparent cause.

Stress affects different animals in different, but useful, ways

Animals feel stress when they experience actual dangers—such as a zebra chased by a lion. Humans often feel stress from worries, memories, or even thoughts about problems that may occur in the future. For this reason, animals tend to experience stress in short, intense bursts. Conversely, people can feel stressed for long periods, which can eventually be harmful to their health.

How we frame stress—as good or bad—seems to alter how it affects us

This podcast discusses research that indicates stress perception may drastically affect how we respond to it. In research exploring if our stress is presented as diminishing our health versus if we're told it enhances our performance, it will lead to differences in how successful participants are at performing tasks—with the enhancers doing better.

Fearology, or the study of fear, explores the difference between stress and fear

Our brains involuntarily respond to our environment and signal alarm when that isn’t always needed, triggering responses that include goose bumps. But understanding fear and how to talk our brains into calming down can improve daily life.

Stress-induced hormones contribute to gray hair

When the body experiences stress, the sympathetic nervous system releases the hormone norepinephrine. This hormone prematurely activates pigment-producing cells (melanocytes) in hair follicles, which depletes the hair's ability to retain color over the long run.

Consuming true crime media can increase stress and anxiety

Consuming true crime media can activate one's sympathetic nervous system, which controls the fight-or-flight response. Staying in this heightened state of vigilance can lead to stress-related illnesses, including hypertension, and mental conditions, including depression and anxiety. Additionally, people who actively consume crime news, whether they consider it to be entertainment or educational in nature, report being more fearful of crime, regardless of actual crime rates.

Short-term cortisol spikes can boost the immune system

Elevated acute levels can enhance the immune system's ability to fight off infection or respond to injury. Chronic heightened cortisol levels, however, can lead to inflammation that harms cells and tissues over time.

Touch deprivation can heighten anxiety and depression

Pacinian Corpuscles are pressure receptors just under the skin that send signals to the vagus nerve in the brain—that's the cranial nerve which regulates involuntary actions like breathing, heart rate, and the general "fight or flight" response. Activating those receptors can slow the heart, decrease blood pressure, and lead to the release of oxytocin and cortisol. The absence of touch, conversely, can promote negative feelings.

Some claim breathwork can improve mental health, help process trauma, and more

Research shows people who practice breathing exercises see a decrease in depression and stress levels, and that such exercises are about as effective at treating PTSD as conventional approaches. Even something as simple as extending exhales can slow one's heart rate and activate the parasympathetic nervous system.

Developing adaptable brain-body systems lets athletes thrive beyond 30

Success in high-level sports after age 30 relies on physical fitness and building brain resilience through deliberate training, recovery, and stress regulation. This creates a feedback loop where body and mind reinforce each other.

Panic attacks are intense fear episodes that often occur without a clear trigger

Unlike typical fear responses to real danger, panic attacks can mimic serious health problems, such as heart attacks. Sweating during a panic attack may seem random, but it's a leftover survival mechanism that made it easier for our ancestors to escape by slipping out of an attacker’s grasp.

The limbic system drives emotion, memory, and survival instincts in the brain.

This interconnected group of brain structures—including the amygdala, hippocampus, thalamus, and hypothalamus—processes emotional responses, regulates bodily functions, and plays a key role in memory and learning.

Three examples of how humans are still evolving

For much of nature, natural selection and "survival of the fittest" still play a dominant role; only the strongest can survive in the wild. As little as a few hundred years ago, the same was true for humans, but what about now?

Retrieval cues trigger memories and emotions from long-term storage

Retrieval cues can activate specific cells in a neural network, creating a cascade of neurons that collectively make up a memory. Specific cues help regulate emotions during stress by activating positive memories.

Sleep deprivation leads to buildup of danger molecules in the gut

Fruit flies genetically engineered to be awake for as long as they live tend to live half as long as their well-rested brethren. Analysis shows these modified flies suffer from a buildup of DNA-destroying reactive oxygen species in their guts. When enabled to sleep, the flies live as long as their counterparts.

Over time, people develop a resistance to spicy foods

TRPV1 is a receptor in the body that detects potentially harmful things and responds in a variety of ways, including sweating, tearing up or a runny nose. Over time, more exposure to spicy foods can build up a resistance that minimizes these reactions.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

About 12.5% of US adults experience a phobia in their lifetime, a diagnosis that hinges on the intense fear interfering with daily life and persisting for at least six months.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Chaos theory—informally known as the butterfly effect—is the reason why weather forecasts are presented with probabilities rather than certainties.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

Watch what the Ebola virus does inside our cells and organs in order to spread and survive.

Poison ivy will likely become both larger and more resilient due to climate change.

US consumers collectively owe more than $1T to credit card companies—almost as much as they owe in auto loans.

How fusion—which releases energy when two lighter atoms combine to form a heavier atom—differs from fission

The power and influence of the American presidency have expanded significantly over time—far beyond what the founders envisioned.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

The word 'jazz' evolved from 'jasm,' 19th-century American slang for 'energy'

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

Play the role of a student in a game where you try to navigate college and remain debt-free, selecting different income levels, high school experience, race, ethnicity, and more.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

Hedge funds, the private investment firms that trade a wide swath of financial assets, make money by imposing steep fees on investors and from the fund's investment performance.

When caught in the mouths of cardinal fish, seed shrimp release glowing, bioluminescent chemicals, which alert predators of the cardinal fish, prompting the shrimp's ejection.

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.

Existentialist writer Jean-Paul Sartre coined the famous phrase 'Hell is—other people' in his play 'No Exit'

A 2019 Facebook event called on attendees to "Storm Area 51, They Can't Stop All of Us," resulting in countless memes, the creation of a music festival, and eventually the arrests of those who did try to approach the area.