Misophonia is a neurological disorder where sounds trigger strong emotions

When common sounds become disturbing

Misophonia causes certain sounds to feel violating, triggering a "very visceral kind of experience" filled with extremely unpleasant emotions, including annoyance, anger, and disgust. A 2017 study found that people with misophonia have elevated activity in the brain's anterior insula—a region associated with interoception, emotional processing, and behavioral responses—when exposed to trigger sounds. Ongoing research suggests trigger sound context affects the severity and manifestation of the condition.

Ménière's disease is a long-term, inner ear disorder that causes vertigo

This severe vertigo-causing disorder may involve long and recurrent episodes of vertigo. Symptoms of this disease include balance issues and hearing loss, tinnitus, and a feeling of fullness in the ear. It typically affects only one ear and is linked to a buildup of excess fluid in the inner ear.

Anosmia is the total loss of the sense of smell

This type of loss—due to disease or trauma—has ripple effects, including an altered or limited sense of taste. This video details the anatomy and physiology of our sense of smell and taste and how these senses are interrelated.

Hear examples of what tinnitus can sound like to those suffering from it

This video, from a Scottish branch of the UK National Health Service, features different types of ringing, crackling, and other sounds that tinnitus sufferers experience. Individual responses to such phantom sounds may vary widely.

Noise-canceling headphones cancel out environmental sounds with sound of its own

If sound waves are perfectly out of sync, they can undergo destructive interference, canceling each other out. A microphone in noise-canceling headphones picks up external sounds, and an out-of-sync version is emitted to cancel them out in your ears.

Fear or disgust related to clusters of holes and cracks, called trypophobia, may stem from evolutionary processes to help us avoid pathogens.

Age-related hearing loss, known as presbycusis, is a top cause of hearing loss

This video walks through the biology of why presbycusis (prez-buh-kyoo-sis) occurs and its etiology. This type of hearing loss is gradual and typically starts with reductions in the ability to hear high-pitched sounds.

Lesser-known phobias include turophobia, or the fear of cheese, and nomophobia, the fear of being without your cell phone

19.2M Americans suffer from phobias, including extreme fears of spiders, snakes, heights, and flying.

The brains of people who experience frisson have unique neural pathways

A small 2016 study aimed to investigate the behavioral and neural differences between 10 individuals who experience goose bumps when listening to music and 10 who typically don’t. Scientists reported that individuals experiencing musical chills had greater white matter connectivity in specific auditory, emotional, and social processing areas of the brain.

Visualizing a synaesthetic soundscape

Artist Michal Levy has chromesthesia, a subtype of synesthesia in which sounds and music trigger involuntary associations with and sensations of color. This condition gives Levy a unique artistic perspective and ability to interact with and interpret music. In this short animation, Levy tries to capture her audiovisual experience of 'Giant Steps," considered a landmark composition in jazz history by musician John Coltrane.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

What (and why) is ASMR?

ASMR podcasts and videos are appearing all over social media, so what exactly is it, and what does it do? This immersive article explains the phenomena of ASMR, which stands for autonomous sensory meridian response. ASMR is when certain sounds or...

How the feared self fuels OCD

Obsessive-compulsive disorder is characterized by intrusive thoughts that prompt people to enact compulsions—behaviors intended to relieve the anxiety or stress from the obsession. A significant intrusive thought OCD sufferers endure is the fear they will become a dangerous or immoral person. Therapeutic approaches try to show patients this is just a story that can be set aside.

Some researchers have labeled nomophobia, the fear of being without your phone, as 'the phobia of the 21st century.'

How menopause affects mental health

Menopause, a natural biological process, occurs in three stages: perimenopause (hormone fluctuations), menopause (end of menstrual cycles), and postmenopause (12 months without menstruation). Hormonal shifts during this time can affect neurotransmitters, increasing the risk of mood disorders.

Over time, people develop a resistance to spicy foods

TRPV1 is a receptor in the body that detects potentially harmful things and responds in a variety of ways, including sweating, tearing up or a runny nose. Over time, more exposure to spicy foods can build up a resistance that minimizes these reactions.

Listen to how the gut microbiome influences your emotions

The gut-microbiome connection may involve the enteric nervous system, a collection of hundreds of millions of neurons throughout the gut that transmit signals up the vagus nerve to the brain.

There's an official term for the sound your stomach makes before intense diarrhea

It's borborygmi. The sound is produced when gas or liquid moves through the bowel. Peristalsis, the wave-like muscle tightening process that typically pushes food through the digestive system, produces the sound as it tries to push these substances through the body.

The word allergy is partly derived from the Greek word 'allos' for 'other'

For people with allergies, their immune systems recognize substances as a harmful "other"—cuing an inflammatory response. This podcast explores allergy details and related topics, including how scientists are interested in if the same allergic response mechanisms could underpin other health issues, including severe, painful symptoms around the time of menstrual cycles. Since estrogen acts on white blood cells called mast cells, which leads to the release of histamines—similar to what happens during allergic responses—an understudied question is whether the same process is fueling some of the uncomfortable symptoms around menstruation. An allergist guest notes this raises questions about if antihistamine medications like Pepsid might alleviate them, something that hasn't yet been explored in clinical trials.

Why does the body have a stress response?

When encountering a stressful situation, the human body typically goes into what is known as "fight-or-flight" mode. Because it evolved as a survival mechanism, the biochemical response enables people and other mammals to react quickly to life-threatening situations. The carefully orchestrated yet near-instantaneous sequence of hormonal changes and physiological responses helps someone to fight the threat off or flee to safety.

Noise from data centers may disrupt wildlife and local residents

Individuals living where local ordinances have allowed data centers to be built next to residential areas have reported that the constant humming and vibrations from cooling systems have prevented them from sleeping and exposed them to chronic noise, which the American Public Health Association says can lead to cardiovascular disease and increased stress.

Some animals possess sensitive hearing to help pinpoint prey and map the world

Bats and dolphins produce sound to reflect off surfaces and create a mental image of their surroundings. Owls' faces are dish-shaped to help funnel sounds to their ears, including that of mice moving along leaves or snow. Pinnipeds, such as seals and walruses, hear in both air and water.

Emotional crying is an important and cathartic process

Though babies don't initially produce tears when they cry, this podcast discusses how humans are hardwired to cry throughout life. Most crying research relies on self-reporting of crying and emotions. This podcast notes that there aren't neuroimaging studies of crying—they're quite expensive to complete. As a result, the brain precursors and processes during a bout of crying remain understudied.

Multiple sclerosis means 'many scars'

That's a reference to the scarring or lesions that occur in the brain, spinal cord, and elsewhere whenever the immune system has a flare-up. The immune system attacks the myelin because it incorrectly responds as if it's a threat, damaging the body's ability to transmit electrical signals effectively from areas of the body to the brain.

If you have a cold, the body produces excess mucus to trap germs

This process clogs up narrowed nasal airways, which results in congestion. This process is often accompanied or triggered by swelling of blood vessels in the nose.

Key symptoms of burnout can be both mental and physical

Burnout can be accompanied by several symptoms, including low energy and chronic fatigue, trouble concentrating, difficulty sleeping, and depression. It may even manifest physically as musculoskeletal pain, headaches, stomach and intestinal pain, and more. More intense cases have been linked to cardiovascular and mental health disorders.

Opioids mimic naturally produced endorphins to dull pain

Once in the body, opioids bind to naturally occurring opioid receptors typically used by endorphins to temper pain. They trigger the release of dopamine, a desire-related hormone, and decrease noradrenaline, a neurotransmitter involved in heart and breathing rate regulation, meaning high doses can slow these processes to dangerous levels.

What are the phases of migraine?

Migraine attacks don't happen all at once. This interactive walks users through the phases of migraine. Scroll through this visual guide to migraine phases to learn more about migraine, related symptoms, and brain activity.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

Poison ivy is in the same family as mangoes, cashews, and pistachios—and they all produce oily urushiol in their raw, unprocessed state—but they are typically prepared in ways to avoid causing human discomfort.

Fireworks make a loud booming sound after exploding due to air expanding faster than the speed of sound.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Fish populations in the Great Barrier Reef have increased after installing waterproof speakers on the ocean floor that played recordings of sounds from healthy coral reefs.

Pure water does not conduct electricity because this flow of energy requires the movement of charged particles, and water is a neutral molecule.

This real-time tracking of the hantavirus cruise ship outbreak in May 2026 offers a unique glimpse into the global reach of the outbreak and whether the virus sickened passengers and their communities around the world.

American short story writer Flannery O'Connor raised 40 peacocks, which became potent symbols for her fiction's elegant violence

See photos of Meteora, a mountainous site in central Greece, home to 14th-century monasteries perched atop soaring outcroppings.

Use this calculator to find the dollar value of your mental load, from meal planning to coordinating after-school care for your children.

Chaos theory—informally known as the butterfly effect—is the reason why weather forecasts are presented with probabilities rather than certainties.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

View the ten deadliest tornadoes in US history.

Hear 50 years of iconic hip-hop samples, the genre's foundational looped tracks

Volcanoes 'die' when their supply of magma runs out, if they are shifted away from their underlying magma reservoir, or if they get clogged by collapsing or their magma cooling back into rock.