The brains of people who experience frisson have unique neural pathways

Music may give some of us the chills and goose bumps—perhaps because it shocks us

The science is still unsettled about why music can trigger a chill down your spine, formally known as frisson, but one theory is that anything surprising to the nervous system—including sudden beat drops or unexpected harmonies—stimulates a type of alarm response that gives rise to this feeling.

50 years of research has focused on unraveling the relationship between music and frisson

One insight reveals that musical passages with surprising volume changes or unexpected harmonies and beauty are more likely to trigger frisson, perhaps because they upend listeners' expectations.

Some of us can control our goose bumps

A small 2018 study examined the rare ability to control goose bumps. Researchers found some intriguing associations between having a particularly open and curious personality type and the ability to trigger this sensation—a link that they hope will be explored further in the future.

There’s a lot we still don’t know about goose bumps in humans

Though goose bumps can be associated with changes in skin temperature, the biggest gaps in our understanding are around measuring goose bumps from nonthreatening exposures. These bumps can often occur without our detection, and we have trouble correctly identifying them. The relationship between emotionally induced chills and goose bumps can also be tenuous.

Scientists have unraveled new details about which nerve cells control goose bumps

Research in 2016 revealed that at least eight different types of neurons are associated with the sympathetic nervous system. One finding revealed that goose bumps and nipple erection are caused by neurons specialized to regulate these specific functions by controlling the erectile muscles in those tissues.

Goose bumps are often triggered by emotions

A physiologist and professor of zoology explains that the subconscious release of adrenaline, a stress hormone, causes a contraction of skin muscles. It’s released in several situations, including when humans are cold, afraid, or feel strong emotions. (Some readers may experience a paywall.)

Audio and visual cues from "Titanic," Pink Floyd, and more can provoke goose bumps

These audio and visual snippets have been used in research studies to elicit goose bumps.

Playing music enhances the creation, storage, and retrieval of memories

Scans of the brains of individuals who play instruments have shown enhanced connectivity between multiple brain regions—visual, auditory, and motor cortices—and the corpus callosum, which connects the two brain hemispheres. These complex connections are strengthened through practice and then used in other activities that involve both logic and creativity. The brains of musicians also appear to give experiences multiple types of memory tags, such as audio, emotional, and conceptual, improving their processing.

Fearology, or the study of fear, explores the difference between stress and fear

Our brains involuntarily respond to our environment and signal alarm when that isn’t always needed, triggering responses that include goose bumps. But understanding fear and how to talk our brains into calming down can improve daily life.

Individuals with synesthesia experience involuntarily overlapping sensations

Tasting words or seeing colors in music results from the brain retaining extrasensory connections from infancy. While most lose these neural pathways during development, about 4% of people are synesthetes, maintaining them without realizing it's unusual.

Why do you shiver when cold?

Humans are warm-blooded creatures, so our bodies like to maintain internal temperatures separate from and typically above those in their environment. This is made possible by a process known as thermoregulation. When the brain's hypothalamus senses a drop in the body's core temperature, skeletal muscles may be ordered to shiver, sending out waves of muscle contractions and exothermic biochemical reactions whose byproduct includes heat and energy.

The neuroscience of heartbreak

An analysis of functional MRIs revealed a difficult fact: the active brain areas of people experiencing heartbreak were very similar to those actively in love. This is a major reason why people in the middle of rejection can't accept the reality of their loss. This article breaks down the various changes in neurotransmitters and neural pathways for those enduring that universal experience, heartbreak.

Researchers recently took an unprecedented look at the neural effects of psychedelics

According to analysis published in 2026 that looked at more than 500 brain scans pooled from 267 people who took psychedelics, the drugs increase connectivity between different brain regions within minutes of taking them, including transmodal networks (tied to thinking) and unimodal networks (involved in visual and sensory perception).

How science explains déjà vu

Take a fun look at the science explaining the odd experience of déjà vu, which some theories suggest is actually a sign of a healthy brain.

Nine different studies exploring animals' relationship to music

Researchers have conducted multiple studies attempting to answer a certain question: do animals like human music? Across species, they observed different results and no clear pattern. Primates appear to prefer silence, and cockatoos appear to dance to funky beats.

Neural replays in mice help explain food aversions

Princeton University scientists published research in 2025 analyzing how mice learn to associate certain foods or flavors with feeling ill—even when there’s a time gap between eating something and feeling sick. The work, performed with grape Kool-Aid and injections of a substance that made mice sick, traced the literal “gut reaction” of how gut distress signals are linked to neural replays of what the mouse ate.

The "reminiscence bump" causes memories from adolescence to last

Research shows that the "reminiscence bump" phenomenon, which applies to memories formed between the ages of 10 and 30, contributes to songs from those ages triggering the most intense nostalgia. This may be due to biological and hormonal changes enhancing memory effectiveness during adolescence.

Like fingerprints, brain anatomy is unique too

Researchers have discovered that a combination of experiences and genetic factors shape the anatomy of the human brain. They found even quick experiences affect the brain’s genetic makeup, which—over time—means every person develops a completely unique brain anatomy. While brain imaging could be used to identify individuals, it remains much more expensive than fingerprinting for now. Read to found out more about this study from the University of Zurich.

Why do dreamers twitch?

This thought-provoking piece highlights newer research suggesting sleep twitches may not be random dream leftovers, but instead a crucial way our brains map and understand our bodies. From sleeping rat pups to dreaming octopi, this biological mapping system appears universal across animal species.

Misfired motor signals may explain why many people with schizophrenia hear voices

Up to 80% of schizophrenia patients may have auditory hallucinations. Recent research concluded that this symptom may be from misfired motor signals that feed into each other, essentially failing to suppress certain sensory neural activities and that resulting overexcitment fuels hallucinations. The finding suggests that, one day, magnetic pulses might be used to stimulate specific nerves to better regulate the errant signals and reduce or stop hallucinations. (Some users may encounter a paywall.)

When common sounds become disturbing

Misophonia causes certain sounds to feel violating, triggering a "very visceral kind of experience" filled with extremely unpleasant emotions, including annoyance, anger, and disgust. A 2017 study found that people with misophonia have elevated activity in the brain's anterior insula—a region associated with interoception, emotional processing, and behavioral responses—when exposed to trigger sounds. Ongoing research suggests trigger sound context affects the severity and manifestation of the condition.

How brain cells carry information

At any moment, there is an electrical storm coursing through your body. Discover how chemical reactions create an electric current that drives our responses to everything from hot pans to a mother’s caress.

Some people may be genetically predisposed to loving roller coasters

Recent studies indicate that individuals with higher levels of dopamine may be more prone to thrill-seeking behaviours like riding roller coasters or even doing drugs or shoplifting.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

Itching is caused by stimulated nerve cells in the skin

Scratching produces low-level pain signals to the brain, distracting from the itch. Scratching also releases serotonin, a neurotransmitter that creates a happy sensation, which resets the itch signal. This can cause a cyclical itch-scratch cycle.

Parents and romantic partners naturally touch at speeds optimizing nerve activation

A small observational research study shows that when parents are asked to caress their infants and volunteers are asked to caress their partners, both groups spontaneously stroke their loved ones at velocities that, on average, fell within the optimal range to stimulate the C-tactile afferent nerve receptors. This wasn't the case when volunteers were asked to do the same with an artificial arm, which they stroked much faster.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Fear or disgust related to clusters of holes and cracks, called trypophobia, may stem from evolutionary processes to help us avoid pathogens.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Fish populations in the Great Barrier Reef have increased after installing waterproof speakers on the ocean floor that played recordings of sounds from healthy coral reefs.

Stars appear to twinkle because turbulence in the motion of molecules in Earth's atmosphere causes light to bend and wiggle rapidly on its way to the surface—a phenomenon called scintillation.

Ebola infects and disables immune cells, triggering a cascade of events that leads to small blood clots throughout the body, weakening blood vessels and interrupting blood flow to key organs.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

A century of Billboard issues documenting the evolution of popular music.

Poison ivy can cause rashes year-round since all parts of the plant contain urushiol, the oil that triggers our allergic response.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

The Dracula character, now seen as the vampire archetype, was inspired by a seafood-induced nightmare its creator experienced.

Explore chaos in this simulation of two double pendulums, where small differences in the release angles produce wildly different outcomes.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

In 2026, Finland was named the world's happiest country for the ninth consecutive year based on its wealth, social safety network, and high life expectancy, among other factors.

The Great Salt Lake's distinct dual coloration results from high-salinity organisms that only live in the northern portion and produce a purple protein.

Georgia O'Keeffe's flower paintings are often assumed to be sexual, though the artist claimed she was simply interested in highlighting the beauty of flowers that most people neglect

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.