Extremophiles
Overview
Extremophiles are organisms that flourish in environments lethal to most living things. Unlike extremotolerant organisms, which can temporarily withstand conditions such as frigid temperatures or high acidity, extremophiles have adapted to them and often cannot survive outside such environments. Since their discovery in the 1960s, extremophiles have reframed what scientists understood to be the requirements for life, expanding the extent of Earth's biosphere and the list of places where astrobiologists search for life in the cosmos.
Extremophiles are classified according to the seemingly deadly circumstances they prefer for their habitats. Thermophiles live in scorching environments, such as hot springs and areas near underwater volcanoes, but psychrophiles prefer glaciers, permafrost, and deep-sea waters. Halophiles thrive in very salty locations, while acidophiles and alkaliphiles can survive in high- and low-acidity waters, respectively. Among the most impressive organisms are polyextremophiles that can live in multiple extremes, such as Deinococcus radiodurans, which has survived in outer space.
Extremophiles' capabilities largely stem from their possession of extremozymes—proteins that facilitate critical biochemical processes in unconventional environments. These biocatalysts have been used in similar industrial settings, including biofuel production, food processing, and pharmaceutical manufacturing, to reduce the reliance on more harmful methods. They also provide an eco-friendly means of cleaning up radioactive or chemically contaminated sites.
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