Engrams are the specific pattern of brain cells that make up a memory

Memory exists as multiple types stored across various brain systems

Memory isn't one uniform function—it's made up of multiple systems, like declarative (facts/events) and non-declarative (skills/habits), which involve different brain areas such as the hippocampus, amygdala, and cerebellum.

The brain consolidates memories during sleep

During sleep, the brain appears to process memories from the day and encode them into long-term storage. At the same time, the brain prunes old memories out of the brain that are no longer useful. Understanding this process also sheds light a various neurodegenerative diseases.

Memories are formed through attention, repetition, and emotional significance

Our brains create memories by taking in sensory input, filtering it through short-term memory, and storing it in long-term memory. Emotional events are more likely to become vivid, lasting memories because they activate stronger neural connections.

Sharp wave ripples in the brain tag experiences for long-term memory storage

These ripples were known to quickly replay neuronal sequences during sleep for consolidation. While awake, they help the brain prioritize memories to remember, and their disruption can impair memory formation.

Memory disorders disrupt the brain's ability to make, store, or recall memories

These disorders stem from reversible issues like vitamin deficiencies or irreversible causes such as stroke or dementia. Only one type of dementia—familial Alzheimer’s disease—is directly inherited and accounts for about 20% of Alzheimer’s cases.

Researchers use the brain's ability to edit memories to explore memory deletion

Scientists have successfully implanted false memories in mice after studying how the editing process works in the brain. Beyond potentially deleting memories in those with PTSD, upcoming research may allow clinicians to forecast the onset of neurodegenerative diseases.

Researchers believe the brain consolidates memories, processes emotions, and plans for the future during dream states

Can brain scans help with processing trauma?

MRIs and brain monitoring therapies are becoming increasingly popular for those looking to process trauma and address mental health conditions, including PTSD and depression. This article details how these therapies quantify mental health, giving users another way to measure and manage their mental and emotional needs through brain mapping and other methods.

Some dementia cases may be linked to microorganisms in the brain

Researchers now know that, much like the gut, the brain is home to an ecosystem of microorganisms—the brain microbiome. While this area of study is still new, some scientists believe 50% of bacteria-caused dementia cases could be treated. (Some users may encounter a paywall.)

See how computer memory really works—from binary bits to modern RAM

The video explains how computers store information as 1s and 0s, how RAM functions as fast working memory, and why systems utilize different types of storage. The video demonstrates how this process enables computers to operate.

What sleep loss does to the brain

Proteins in the brain perform various critical functions, such as helping neurotransmitters function or enabling electrical activity in the organ. These proteins must fold in specific ways to perform their duties, similar to paper airplanes. Sleep deprivation contributes to the gathering of misfolded proteins that aren't shaped correctly for their roles and so accumulate in undesired spaces, such as in the gaps between neurons.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Like fingerprints, brain anatomy is unique too

Researchers have discovered that a combination of experiences and genetic factors shape the anatomy of the human brain. They found even quick experiences affect the brain’s genetic makeup, which—over time—means every person develops a completely unique brain anatomy. While brain imaging could be used to identify individuals, it remains much more expensive than fingerprinting for now. Read to found out more about this study from the University of Zurich.

How does muscle memory work?

Muscle memory is less about remembering how to ride a bike and more about what's happening in muscle cells. Increasing the cells' size, say by working out, leads to an increase in nuclei, which increases the production of mitochondria. When your fitness regimen falls to the wayside and you decide to re-enter the gym, these gains-based nuclei are already present to quicken muscle cells' adaptation to exercise.

Neurons send signals through electrical impulses and chemical messengers

By converting electrical signals into chemical messages at synapses, neurons allow information to travel throughout the nervous system. With repeated use, synapses grow stronger, enhancing the associations between neurons.

CRISPR-Cas systems act as genetic memory banks for defending bacterial cells

When viruses called phages inject DNA into bacteria, some bacterial species store bits of this DNA in their own genomes. This allows them to recognize and destroy the same virus if it attacks again.

The Armamentarium is a set of new gene therapy tools to fight brain diseases

Research from 29 universities and institutions across North America has resulted in the development of 1,000 tools that provide large-scale, cell-type specific targeting for the first time. These tools may be used to alter the activity of brain cells to address some neurological diseases and sleep disorders.

Neural networks are modeled after an idealization of the brain

These networks—including the backbone of ChatGPT-3, which has approximately 175 billion parameters—naturally discover the implicit rules of grammar and syntax within language by identifying patterns. Deviations in word patterns add creativity to the text generation.

Repeated head injuries can lead to CTE and early dementia

Chronic traumatic encephalopathy is a progressive neurodegenerative disease caused by repeated trauma to the head. The condition has become a particular concern in sports like football and soccer, from youth to professional leagues, where repeated low-level concussive events are likely.

Why patterns in art are so pleasing

Repeated visual cues like shapes or lines derive from the brain's innate compulsion to identify faces, places, bodies, and more. With repeated shapes, the brain seeks out resolution to the subtle variations between them. See examples in art and music.

What is a cell? A great quick overview.

YourGenome.org furnishes a collection of information on cells and how they work. Every body has trillions of cells, each serving a specific function: making proteins, processing chemicals, and creating energy. Every cell contains a genome, a set of instructions for the cell's function. Brush up on your cells for a better grasp on genetics.

Super recognizers may use specific facial features to commit faces to memory

Researchers believe that recognizing individuals seen only in passing, even decades later, is an ability of genetic origin and specific to facial recognition, rather than a result of better overall memory or perception. Applying eye tracking data from super recognizers to AI has led to improvements in facial recognition software.

How the brain processes a calendar year

When most of us picture a calendar year, we have a foggy image in our minds of the months, in rough, calendar-like grids. But for some folks, that picture is a whole lot more clear. Around 1 percent of the population has a strange ability known as "calendar synaesthesia," which means they're able to visualize in crisp detail an elaborate calendar of the months of the year. Learn how it works here.

Multiple sclerosis means 'many scars'

That's a reference to the scarring or lesions that occur in the brain, spinal cord, and elsewhere whenever the immune system has a flare-up. The immune system attacks the myelin because it incorrectly responds as if it's a threat, damaging the body's ability to transmit electrical signals effectively from areas of the body to the brain.

Some animals may anchor their brain cells to specific landmarks to determine direction

In a study of bats exploring a new area, specific sets of "head direction cells" were seen becoming active based on bats' orientation when moving, and this activity became more coordinated over time. Researchers suspect, like humans, bats and other animals establish this sense of direction based on movement relative to known points of interest.

Fearology, or the study of fear, explores the difference between stress and fear

Our brains involuntarily respond to our environment and signal alarm when that isn’t always needed, triggering responses that include goose bumps. But understanding fear and how to talk our brains into calming down can improve daily life.

Visualizing a stroke at the microscopic level

By far the most common type of stroke is what is known as an ischemic stroke. This occurs due to either an embolus (a blood clot that travels to the brain from elsewhere in the body) or a thrombus (a blockage that forms within the brain itself).

Tattoos remain visible on your skin thanks to immune cells called macrophages

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

According to the physics of black holes, our 4D reality may be a hologram—a projection of information coded on a 2D surface on the edge of the universe.

Explore what it's like inside a patient isolation unit, used in situations such as treating a patient or suspected patient with Ebola.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

Graffiti dates back to at least ancient Pompeii, where citizens scrawled messages to one another on public walls

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

Search a massive database of over 4 decades of clues from the TV quiz show 'Jeopardy!'

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Power lines are dotted with large, brightly colored balls to improve the visibility of these thin wires to helicopters and small planes and help prevent potential crashes.

The word 'jazz' evolved from 'jasm,' 19th-century American slang for 'energy'

Explore an interactive map of battles from the American Revolution, along with detailed summaries of each engagement