Explore what it's like inside a patient isolation unit, used in situations such as treating a patient or suspected patient with Ebola.

Watch the cumbersome, but necessary, precautions healthcare workers must take to care for and protect themselves while caring for Ebola patients.

Watch the cumbersome, but necessary, precautions healthcare workers must take to care for and protect themselves while caring for Ebola patients

Treating someone with Ebola involves a painstaking process of suiting up (donning) and peeling off (doffing) protective gear. Doctors follow detailed CDC guidelines. Properly suiting up is key to protecting against fluids that transmit Ebola, and correctly removing a suit that could be contaminated with the virus is also critical.

Watch what the Ebola virus does inside our cells and organs in order to spread and survive.

Watch what the Ebola virus does inside the body in order to spread and survive

Once infected, the virus targets the body's immune cells, spreading the infection throughout the body. Patients exhibit severe flu-like symptoms. Ebola then targets the liver, which produces proteins that help blood clot, and the adrenal glands, which control blood pressure. The immune system may overreact to the viral invasion, releasing a cytokine storm that can result in shock, multiple organ failure, and death.

There have been close to 40 Ebola outbreaks since 1976

Ebola is a rare but deadly virus that causes severe illness, organ damage, and sometimes internal bleeding. It spreads through contact with infected bodily fluids and is most common in parts of sub-Saharan Africa. This explainer covers its symptoms, transmission, and treatment options.

See the evolution of Ebola vaccine and treatment development.

See how Ebola tore through Guinea, Sierra Leone, and Liberia in 2014-2016.

The 2026 Ebola outbreak is hampered by a lack of vaccine against the species of the virus, heightening the need for rapid tests to aid in disease control

Clinics in the Democratic Republic of Congo saw patients with Ebola symptoms months before the disease was identified. The identification lag was due to inadequate diagnostics that could not accurately or quickly identify the virus's myriad species. Contact tracing and better diagnostics will be required to tamp down the outbreak.

See how Ebola tore through Guinea, Sierra Leone, and Liberia in 2014-2016

Frontline traced how the outbreak started and spread across West Africa. documenting first-hand accounts and patient experiences. This Ebola outbreak was the deadliest to date, resulting in over 11,000 deaths.

Learn how monoclonal antibodies, which mimic the body's antibodies, can fight diseases like Ebola.

The 2026 Ebola outbreak is hampered by a lack of vaccine against the species of the virus, heightening the need for rapid tests to aid in disease control.

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

Scientists have struggled to pin down Ebola's natural reservoir species for decades, but the available evidence suggests that it's very likely fruit and insect-eating bats found in Africa.

Ebola's natural reservoir species are likely bats

But the virus doesn't seem to sicken the animals, so capturing an infected bat and performing necessary tests has remained challenging. Though many scientists believe fruit bats are the reservoir species for the virus, Ebola viral RNA fragments were detected in a greater long-fingered bat captured in 2016 in Liberia. The species isn't a fruit bat—it roosts in caves and feeds on insects. The scientist behind the discovery states that he believes the virus likely infects multiple host species and that the hosts may differ regionally. (Some users may encounter a paywall.)

Ebola species have historically been named after where they were discovered, stigmatizing residents who live there, including Bundibugyo, in Uganda.

How the most famous Ebola outbreak book got aspects of the disease so wrong

Richard Preston's 1994 book The Hot Zone brought knowledge of Ebola to the masses. But, beyond the poor portrayals of the science and the scientists, the book fostered fearmongering about Ebola, with portrayals of "liquefying," "dissolving," and "bleeding out." These falsehoods about Ebola have persisted for decades and appear to be reinvigorated with every new emergence of the disease.

Ebola is a filovirus, meaning it resembles a thread under a microscope, though it sometimes twists and can resemble a bowl of spaghetti.

Cultural norms about how to handle the bodies of loved ones in communities in West Africa have hampered Ebola responses.

How the most famous Ebola book, The Hot Zone, which sold 3.5 million copies and was translated into 30 languages, got aspects of the disease so wrong.

Marburg virus, related to Ebola, is also extremely deadly, and has no available vaccine.

Mapping the spread of a dangerous fungus growing in US healthcare facilities

Explore the data showing how the fungus C. auris has spread in the US, with more than 10,000 reported cases since 2016. Recommended steps to prevent infections and limit their spread have been successful in some areas, but infection control remains complicated because the fungus is often now multidrug-resistant.

As an experiment, the first B2 mission highlighted the challenges of isolated systems

Some argue that isolation from the outside world was compromised—making the experiment a failure—when a crew member was taken from Biosphere 2 for surgery and returned hours later. This position was strengthened when it was revealed that oxygen had been pumped into the facility.

Explore 3D models of some of the most dangerous viruses

Everyone has come in contact with common viruses—typically something like influenza (the common flu)—but sometimes they encounter more dangerous strains. While we're familiar with the symptoms that manifest, it wasn't until the advent of advanced microscopy that scientists could pin down the exact structure and behavior of various viruses.

Explore a typical layout of an emergency department

This architectural diagram illustrates the layout of an emergency area. It provides insights into a typical emergency room organizational system to provide context for patients as they flow from entry through triage into treatment.

Watch an expert's take on the rare disease hantavirus—and why it's not of great concern to the general population

This rare zoonotic disease, transmitted to humans primarily through infected rodent droppings, urine, or saliva, is rarely spread between people. The disease was of particular concern in spring 2026, when an outbreak occurred on a 150-person cruise ship, prompting a flurry of action, including contact tracing for passengers in their home countries. The disease can be fatal. But early care—primarily oxygen support—can help patients survive.

What are zoonotic diseases?

Interspecies interactions are a breeding ground for disease transmission. This basic background information on zoonotic disease from the Centers for Disease Control and Prevention (CDC) chronicles the different ways humans can get sick, identifies what groups are particularly vulnerable, and offers links to other resources.

This is what happens inside your body when you're sick

This video details the biology of what happens inside the human body during illness.

Maryland required cholera researchers to fly a yellow warning flag—signifying quarantine dangers in the 1970s

University of Maryland Hospital researchers intentionally infected volunteers with the cholera bacterium in the late 1970s to further their understanding of the disease. They proceeded with this work following the recommendation of a US government panel. (Some users may encounter a paywall.)

Explore inside a mosquito factory where millions of mosquitoes are bred weekly

In Medellin, Colombia, scientists are infecting Aedes aegypti mosquitoes with Wolbachia, a bacterium that wouldn't otherwise infect the species, but does block its ability to transmit dengue, Zika, yellow fever, and chikungunya. In the wild, infected mosquitoes would breed with wild mosquitoes, pass down Wolbachia, and thus reduce disease transmission.

Read an account of what life was like in America's national leprosarium—its leper colony

José Ramirez Jr. shares an account of his eight years at the 300-acre national leprosarium in Carville, Louisiana, from 1968 through the mid-1970s. Mostly staffed by nuns with nursing degrees, this facility was home to hundreds of people at a time, and it's also the site where they were required to be buried.

This real-time tracking of the hantavirus cruise ship outbreak in May 2026 offers a unique glimpse into the global reach of the outbreak and whether the virus sickened passengers and their communities around the world.

The rare but deadly time bomb lurking after a measles infection

Subacute sclerosing panencephalitis, also known as Dawson disease, is a progressive and fatal neurodegenerative condition caused by a dormant measles infection. Typically, patients recover from measles normally, with the symptoms of SSPE only appearing years or even decades later. The incidence rate in unvaccinated pediatric patients is estimated to be around one in 1,300.

Ibogaine is being investigated for treating mental health issues and substance abuse

This compound, which is illegal to use in the US, has had promising results for patients who have tried it in other countries for substance abuse and mental health concerns. This psychoactive substance is not without risks, however; this TED talk points out it's also caused fatal cardiac arrhythmias and shouldn't be taken without medical supervision.

How the environmental diversity of coral reefs provides potential medical treatments for humans

As immobile animals, corals and the organisms that live on them have evolved a suite of chemical compounds to prevent disease and ward off predators they cannot outrun. These include antibiotics, antivirals, and powerful toxins that target the nervous system and are studied for applications involving pain management and neurological treatments.

The Chernobyl exclusion zone has become a unique wildlife refuge

Within the area—roughly the size of Yosemite National Park—animals such as wolves, bears, and feral dogs descended from the pets left behind have gradually adapted to low-level radiation. Eastern tree frogs in the area have darker skin than usual, which may have helped protect them from ionizing radiation.

In 2020, the league quarantined players in a 'wubble'

When the pandemic hit in 2020, the WNBA delayed the start of their season, choosing to play in a quarantine bubble for a 22-game season. Players choosing to opt in knew the decision wasn't just for them, but for their families. This TNT video explores what it was like for WNBA players to play, practice, and live together for nearly 100 days.

There is a secretive bomb-proof bunker located under the White House

Built in 1942 during World War II, the Presidential Emergency Operations Center lies beneath the East Wing. Designed to protect the president during air raids—and later nuclear threats—it remains a top-secret command site used during crises like 9/11.

Physician teaches course on being a cancer patient

Stanford physician and professor Bryant Lin was diagnosed with stage four lung cancer, a terminal diagnosis. Despite its difficult implications for his life, Lin embraced the chance to teach his students from the unique perspective of a lung cancer patient. The course explored the journey from diagnosis to treatment; how to respect a patient's physical, emotional, and spiritual dimensions; and more.

Horror offers opportunities to safely experiment with fear

Researchers at Denmark’s Aarhus University study people attracted to what they call “recreational fear,” which includes any media (like a horror movie) or experience (like a haunted house) that’s intended to give them a scare. They say these people appreciate playing with fears and anxieties safely.

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Poison ivy was sent to Europe in the 1600s as an exotic, ornamental oddity, where it was purposefully grown in the English royal gardens at Kew, the Faculty of Medicine in Paris, and a few other locations.

NBA superstar Victor Wembanyama spent the 2025 summer training with monks in central China to enhance his body and mind.

Explore the animals that populate the depths of the ocean, from fish and coral in the first few hundred feet, all the way down to the bottom of the Mariana Trench.

In 2018, 26-year-old missionary John Allen Chau was killed by tribesmen after attempting to reach and evangelize on India's isolated North Sentinel Island

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Legendary architect Frank Lloyd Wright designed the SC Johnson headquarters in Wisconsin, aiming to make a cathedral-like workplace

See photos of Meteora, a mountainous site in central Greece, home to 14th-century monasteries perched atop soaring outcroppings.