Ebola's natural reservoir species are likely bats

Bats have evolved to carry viruses without getting sick

Bats—the likely animal reservoir for diseases including Ebola and coronavirus—tolerate viruses without getting sick. The secret lies in evolutionary adaptations allowing bats to become the world’s only flying mammal and to thrive under immense physiological stressors.

Bats are uniquely suited to act as reservoirs of viruses

Some of the deadliest diseases to jump from animals to humans originate in bat species. This rich visualization explores the diversity of bats and the factors that make them efficient vectors for harboring and transmitting disease, from their long lifespans to their migration patterns.

Three Ebola species are responsible for most large outbreaks of the disease, yet the only approved Ebola vaccine is known to work against just one of them.

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

Three Ebola species are responsible for most large outbreaks of the disease

The Ebola Zaire, Sudan, and Bundibugyo species are the three ebolaviruses responsible for most large outbreaks in Africa. Among these, Ebola Zaire is the deadliest, with as many as 90% of cases resulting in death. Ebola Sudan has about a 50% fatality rate and has caused several outbreaks in Uganda. More recently discovered in 2007, Bundibugyo causes death in about 30% of people and has caused two large outbreaks in Uganda and the Democratic Republic of the Congo (DRC) before the spring 2026 DRC outbreak. Taï Forest virus is the rarest and is known to have infected a single person in the Côte d'Ivoire in 1994.

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa

More than 70% of all new infectious diseases originate in animals. Referred to as zoonotic diseases, these are diseases that originate in animals and occasionally spill over or jump from animals to humans. Bats, mosquitoes, and primates have all been linked to spillover events. As human populations push further into previously uninhabited wilderness, animal-human contact increases, and disease spillover is inevitable.

Using mosquitoes to vaccinate bats could curb the spread of deadly diseases

Researchers in China tested a transmissible rabies vaccine in the lab by feeding mosquitoes blood containing the vaccine and observing what happened to bats when they were either bitten by the mosquitoes or fed on them. The bats developed antibodies against rabies and survived subsequent rabies infection. (Some users may encounter a paywall.)

Ebola is a filovirus, meaning it resembles a thread under a microscope, though it sometimes twists and can resemble a bowl of spaghetti.

Watch what the Ebola virus does inside our cells and organs in order to spread and survive.

Ebola is a filovirus, meaning it resembles a thread under a microscope

Filovirus is derived from the Latin word 'filum', meaning 'thread.' That term describes its thin, flexible, threadlike appearance. Originally isolated in 1976, the microscopic image of the Ebola virus is now famous, even portrayed in the movie Outbreak. In fact, Ebola's threadlike appearance can vary in both length and degree of twisting, sometimes resembling a bowl of spaghetti.

Marburg virus, related to Ebola, is also extremely deadly

Discovered nine years before Ebola, Marburg is part of the same filovirus family. While this virus is less contagious, it can still be deadly. Currently, no vaccines exist against this disease. (Some users may encounter a paywall.)

The 2026 Ebola outbreak is hampered by a lack of vaccine against the species of the virus, heightening the need for rapid tests to aid in disease control

Clinics in the Democratic Republic of Congo saw patients with Ebola symptoms months before the disease was identified. The identification lag was due to inadequate diagnostics that could not accurately or quickly identify the virus's myriad species. Contact tracing and better diagnostics will be required to tamp down the outbreak.

Watch what the Ebola virus does inside the body in order to spread and survive

Once infected, the virus targets the body's immune cells, spreading the infection throughout the body. Patients exhibit severe flu-like symptoms. Ebola then targets the liver, which produces proteins that help blood clot, and the adrenal glands, which control blood pressure. The immune system may overreact to the viral invasion, releasing a cytokine storm that can result in shock, multiple organ failure, and death.

The 2026 Ebola outbreak is hampered by a lack of vaccine against the species of the virus, heightening the need for rapid tests to aid in disease control.

Ebola species have historically been named after where they were discovered, stigmatizing residents who live there, including Bundibugyo, in Uganda.

Marburg virus, related to Ebola, is also extremely deadly, and has no available vaccine.

Vampire bats are the only mammal to feed exclusively on blood

Scientists believe their ancestors may have eaten parasites and insects off larger animals until vampire bats started feeding directly from those animals. Colonies work together to stay fed, as a vampire bat can die without just two days of eating.

West Nile has been detected in at least 2 species of reptiles

Birds remain the main reservoir for the disease, but scientists have detected the virus across a wide range of species, including at least 48 mosquito species, over 320 bird species, more than 25 mammals, and two species of reptiles.

See the evolution of Ebola vaccine and treatment development.

See how Ebola tore through Guinea, Sierra Leone, and Liberia in 2014-2016.

How the most famous Ebola outbreak book got aspects of the disease so wrong

Richard Preston's 1994 book The Hot Zone brought knowledge of Ebola to the masses. But, beyond the poor portrayals of the science and the scientists, the book fostered fearmongering about Ebola, with portrayals of "liquefying," "dissolving," and "bleeding out." These falsehoods about Ebola have persisted for decades and appear to be reinvigorated with every new emergence of the disease.

Humans are the only known reservoir of poliovirus

The virus has not been found in any other species, which makes humans the only known reservoir for polio. In laboratory settings, nonhuman primates have also been infected with the virus, but there's no evidence that they contract the virus in nature.

Yes, many animals get malaria—not just humans

Birds, rodents, monkeys, lizards, bats, apes, and livestock are among the species that can become infected with malaria. Infected animals' symptoms often resemble those of humans, including fever, lethargy, loss of appetite and difficulty breathing. Birds will also have ruffled feathers and drooped heads.

How the most famous Ebola book, The Hot Zone, which sold 3.5 million copies and was translated into 30 languages, got aspects of the disease so wrong.

Learn how monoclonal antibodies, which mimic the body's antibodies, can fight diseases like Ebola.

Explore what it's like inside a patient isolation unit, used in situations such as treating a patient or suspected patient with Ebola.

Every virus is classified into 7 groups based on genetic differences

Viruses infecting humans have been named based on symptoms ("chickenpox") or the location or animal in which they were first discovered ("Bolivian Haemorrhagic Fever" and "Monkeypox"). For clarity among scientists and to reduce stigma, virologists classify the 15,000 known viruses (270 of which infect humans) by their basic genetic material.

Some mosquitoes are key pollinators—and eat disease-carrying mosquitoes

​​There are more than 3,500 species of mosquitoes, and only a small fraction of them bite humans. They also play vital roles in the ecosystem: One young elephant mosquito, for example, can eat dozens of smaller mosquitoes that bite humans in just one day. Sometimes mosquito-gobbling species are released by humans to control other mosquitoes.

Watch an expert's take on the rare disease hantavirus—and why it's not of great concern to the general population

This rare zoonotic disease, transmitted to humans primarily through infected rodent droppings, urine, or saliva, is rarely spread between people. The disease was of particular concern in spring 2026, when an outbreak occurred on a 150-person cruise ship, prompting a flurry of action, including contact tracing for passengers in their home countries. The disease can be fatal. But early care—primarily oxygen support—can help patients survive.

Rabies is nearly 100% fatal once symptoms appear

Rabies, a viral disease attacking the central nervous system, is nearly always fatal once symptoms appear. It spreads through the infected animal saliva (typically through bites) and causes encephalitis, leading to severe neurological symptoms and death. See how the lyssavirus—the bugs behind rabies—work once inside the body.

Some North American bats can glow in the dark

After examining 60 museum specimens from six different species, scientists found that all of them emitted light after being exposed to ultraviolet radiation. Researchers are perplexed by this natural phenomenon and are currently unable to deduce the reason behind it.

Wild chimpanzees have been spotted with leprosy lesions

In research published in 2021, scientists reported discovering cases of leprosy in wild chimpanzees from Guinea-Bissau and the Ivory Coast—marking the first time the disease has been found in any nonhuman species in Africa. They confirmed that leprosy was the cause of the deformities by testing the animals' poop for the presence of the disease-causing bacteria.

Cultural norms about how to handle the bodies of loved ones in communities in West Africa have hampered Ebola responses.

The bats that live in and protect Portugal's libraries

Two 18th-century libraries in Portugal, the Joanina Library at the University of Coimbra and the Library at the National Palace of Mafra, are home to colonies of bats. These bats are welcome guests because they eat insects that could damage the manuscripts. Visitors can try to see the bats emerge at nightfall in Coimbra or visit on a rainy day and hear them. While catching a glimpse of the bats in Mafra is difficult, the library displays taxidermied remains of former residents.

Scientists can suck animal DNA from the air

A look at how researchers filtered the air around two zoos and identified genetic material from dozens of species, a technique that could help track and conserve wildlife.

Poison frogs get their toxins from eating insects and mice

Other animals, including royal ground snakes, are able to survive eating poison. Scientists study the creative antitoxin defenses in these animals to discover treatments for poisoning.

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

Epstein-Barr virus—the cause of 'kissing disease' mononucleosis—may be the leading cause of MS

A Harvard study with data from more than 10 million US military personnel found that people that contracted Epstein-Barr virus had a roughly 32-fold increased risk of developing multiple sclerosis. The work, published in 2022, found that Infection of the virus preceded MS onset by a median of five years, raising questions about better Epstein-Barr virus management and potential disease prevention.

This real-time tracking of the hantavirus cruise ship outbreak in May 2026 offers a unique glimpse into the global reach of the outbreak and whether the virus sickened passengers and their communities around the world.

These animals are only found in the Amazon rainforest.

The mighty Amazon River and its surrounding rainforest is home to millions of different species of animals, with new ones being discovered regularly.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

Poison ivy is in the same family as mangoes, cashews, and pistachios—and they all produce oily urushiol in their raw, unprocessed state—but they are typically prepared in ways to avoid causing human discomfort.

See how each of the more than two million known species relates to each other—and to common ancestors—in this zoomable tree of life.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

See these 16 pieces of art evoking phobias of snakes, flying, spiders, and more. 

Fish populations in the Great Barrier Reef have increased after installing waterproof speakers on the ocean floor that played recordings of sounds from healthy coral reefs.

Some renewable energy sources may weaken the resiliency of electric grids by removing outage buffers provided by coal- and natural gas-fired plants, which provide the system with more time to find a new power source if a plant goes down.

Many legends about George Washington, including his supposed wooden teeth and the story of cutting down the cherry tree, lack evidence.