As an experiment, the first B2 mission highlighted the challenges of isolated systems

During the first Biosphere 2 mission, crew members lost 16% of their body weight

Food and oxygen shortages drove the “Biospherians” to split into two factions—one seeking to bring in outside resources and another aiming to maintain isolation for the experiment’s integrity. Psychological stress was exacerbated further by the increasing prevalence of insect pests.

Before Biosphere 2, the Soviet BIOS-3 system tested semi-closed ecosystems

Built from 1965 to 1972, the habitat hosted 10 experiments with crews ranging from one to three individuals who had their air recycled by algae and grew their own wheat and vegetables. However, dried meats were routinely brought into the facility to balance crew members’ diets.

Exposed concrete led to oxygen depletion within Biosphere 2

Instead of being absorbed by plants through photosynthesis to produce oxygen, significant amounts of carbon dioxide were taken up by the calcium hydroxide in the concrete, trapping the oxygen in calcium carbonate and water. This concrete was sealed before the start of the second B2 mission.

An artificial ‘lung’ protects the glass structures making up Biosphere 2

Although confined from much of the surrounding environment, B2 allows sunlight to enter, enabling its plants to engage in photosynthesis. Expansion chambers were built to protect the facility's integrity by managing changes in gas pressure resulting from temperature fluctuations.

Biosphere 2 gradually transformed into a lab modeling environmental disasters

Built to establish a self-sustaining habitat, the privately funded facility was taken over by Columbia University in 1995. Closed-system experiments were halted in favor of investigations focused on the effects of climate change, which continued after B2 was donated to the University of Arizona in 2011.

Read a firsthand account of a participant in the first Biosphere 2 mission

The first crew of “Biospherians” spent four months growing their own wheat and awaiting the ripening of tomatoes, onions, and peppers to make their own pizza. They also raised their own livestock, including chickens, pigs, and two goats named Milky Way and Stardust.

Biosphere 2 revealed limitations in maintaining wildlife in unfamiliar environments

Trees appeared to become weak and more prone to breaking because a lack of wind caused them to no longer need to develop stress wood. The extinction of pollinators—potentially due to an explosion in the population of longhorn crazy ants—was also unexpected.

Questioning the results of life on K2-18b

An analysis of the atmosphere of an exoplanet called K2-18b identified the presence of biosignatures—molecules that are created by living things on Earth. This discovery may indicate life exists beyond Earth, but the lack of environmental data complicates the interpretation of results.

Research suggests the cleanliness of the ISS may make astronauts unhealthy

The International Space Station's sterile conditions deprive astronauts of the opportunity to strengthen their immune systems through microbial exposure. To address this problem, future missions may use probiotic-based cleaners and foster diverse microbes in space habitats.

China developed an artificial closed ecosystem in preparation for a future lunar base

Yuegong-1, also known as Moon Palace 1, was a Beijing facility where volunteers simulated life on a colony and conducted experiments on bioregenerative life support systems to assess their viability in an off-Earth environment. The longest experiment at the 0.04-acre facility lasted 370 days.

Steve Bannon was made CEO of the company in charge of Biosphere 2 in 1994

After providing $200M to launch and upgrade B2 before its second mission, billionaire philanthropist Ed Bass appointed the future political strategist and then financial consultant to help find new investments and bring costs under control. Fearing interference from non-science experts, Biospherians from the first mission vandalized the project.

The setting of the comedy film ‘Bio-Dome’ was inspired by Biosphere 2

The film features characters played by Pauly Shore and Stephen Baldwin who accidentally lock themselves inside an experimental biosphere, mistaking it for a shopping mall, while searching for a bathroom. With a Rotten Tomatoes score of 4%, it is considered one of the best-worst movies of all time.

Inhabiting Mars without terraforming might be accomplished with 'worldhouses'

A network of interconnected, airtight bubbles would require several orders of magnitude fewer materials than those required to re-establish the entire planet's atmosphere to resemble Earth. However, the whole network would be compromised by a single micrometeor impact that destroys the air seal.

An oxygen tank explosion forced Apollo 13 to abort its moon landing

The 1970 mission—intended to be the third lunar landing—forced astronauts Jim Lovell, Jack Swigert, and Fred Haise to focus solely on their survival. They engineered a makeshift filter to handle the carbon dioxide they produced, which exceeded the lunar module's capacity.

Evidence suggests some of the Challenger's crew may have been alive after the explosion

Recovery of the intact crew cabin and later analysis of flight data led investigators to conclude the astronauts likely survived the initial breakup and remained alive during the roughly two-minute descent before the cabin struck the ocean.

The Russian Federal Space Agency enabled the first space tourism journey

NASA refused to take Dennis Tito, who had no formal training as an astronaut, up to the International Space Station. Instead, the American engineer and entrepreneur traveled aboard the Soyuz TM-32 mission and described the initial experience of microgravity after engine shut-off as the "most spectacular" part of the flight.

Explore what it's like inside a patient isolation unit, used in situations such as treating a patient or suspected patient with Ebola.

The origin of cyborgs

The term "cyborg" was coined in a 1960 academic paper discussing what alterations humans would need to undergo to survive in extraterrestrial environments, a venture far "more logical than providing an earthly environment" in space. According to authors Manfred E. Clynes and Nathan S. Kline, Cyborgs with a capital C have incorporated exogenous components that extend their ability to adapt to new environments. Read the paper here.

Mixed reality technology helped make repairs to a quantum physics facility in space

In 2021, astronaut Megan McArthur used a HoloLens to work alongside Earth-based engineers and make hardware replacements to the International Space Station's Cold Atom Lab, the first quantum science facility in Earth orbit. The facility cools atoms to near absolute zero to perform quantum chemistry experiments in a microgravity environment.

Most elements of the International Space Station were installed over two decades

Space shuttles delivered storage carriers, docking compartments, airlocks, solar arrays, and labs, which were assembled in low Earth orbit. The station’s Canadarm2 robotic arm, alongside maneuvering spacewalkers, has assisted with this assembly since its installation in 2001.

Smart cities like Songdo, South Korea, have created isolating environments

Built as a futuristic, eco-friendly city filled with smart features like pneumatic trash systems and app-controlled homes, the town provides limited opportunities for face-to-face interactions amid sterile backdrops. A focus on high-rise housing amplifies the lonely, disconnected atmosphere.

Limited transparency soon after Chernobyl made it a source of conspiracy theories

Some rumors about the event became perceived as more reliable than the Soviet mass media, which had omitted key information during the early days of uncertainty. The resulting theories included CIA involvement in the disaster, three-headed birds, aliens, and a weaponized earthquake.

The Gasbuggy Project detonated a nuclear bomb to fracture underground rock formations

Part of Project Plowshare—a program aimed at finding peaceful uses for nuclear devices—the 1967 experiment sought to extract natural gas trapped within shale in underground New Mexico. Gas radioactivity was found to be excessively high for use without expensive processing, and the project was deemed an economic failure.

View a breakdown of bioremediation strategies, divided into onsite and offsite options

Depending on the contamination's complexity, in situ—onsite—options may be preferred and can include supplying oxygen or nutrients into the existing soil to accelerate the microbial breakdown already present in the environment. Ex-situ methods instead displace contamination for treatment away from the environment and may be used for volatile chemicals that require isolation, though this displacement can also spread contaminants if spilled.

Explore what it's like Inside a patient isolation unit

Containing a contagious disease like Ebola requires strict protective measures. There are several specialized medical wards to contain deadly infectious diseases at hospitals across the U.S. Emory University has one such unit, where 4 patients were treated during the 2014 outbreak.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

Voyager spacecraft defied expectations and only powered down after 47 years in space

Originally built for a four-year mission, Voyagers 1 and 2 used a rare planetary alignment and gravity assists to reach interstellar space. With limited power and aging systems, they will continue to send data until the mid-2030s. (Some readers may experience a paywall.)

After NASA's Voyager 1 captured Earth as a single pixel as it left the solar system in 1990, astronomer Carl Sagan used the image to reflect on humanity's fragility and the responsibility to protect 'the only world we've ever known.'

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

An investigation suggests a Scottish island became awash in forever chemicals via seafoam and seaspray—raising questions about what that means for the safety of other coastal areas.

In 2018, 26-year-old missionary John Allen Chau was killed by tribesmen after attempting to reach and evangelize on India's isolated North Sentinel Island

Apollo astronauts left items in the moon's 'toss zone,' including golf balls, family photos, and bags of human waste, to make room for lunar rocks.

In 1984, Operation Smash Hit intentionally crashed a 239-ton train into a nuclear waste canister at 100 miles per hour to prove the canister's safety, which remained completely intact and lost just 0.29 of its 100 pounds of pressure.

Fish populations in the Great Barrier Reef have increased after installing waterproof speakers on the ocean floor that played recordings of sounds from healthy coral reefs.

In 2009, the nation was gripped by the story of a missing young boy who was believed to be floating over Colorado in a homemade balloon, until it was revealed that he was at home the whole time.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Discover the catastrophic consequences of a failure of the US electrical grid—something that is more likely than many Americans think.

Scientists testing how climate change affects plants found, in a years-long simulation study, that poison ivy grew 70% faster with the resulting extra carbon dioxide.

Dorothy's famous entrance into Oz in 'The Wizard of Oz' relied on analog tricks, including a body double and sepia-toned paint, as much as it did on technology

A 2019 Facebook event called on attendees to "Storm Area 51, They Can't Stop All of Us," resulting in countless memes, the creation of a music festival, and eventually the arrests of those who did try to approach the area.

While the sun's gravity keeps the planets in orbit, their gravity also pulls on the sun, causing it and everything else in the solar system to orbit around a mutual balance point called the barycenter—the true center of the solar system.

For centuries, it was common to sleep in two shifts: a few hours at the beginning of the night, and a longer period beginning around midnight

A vending machine run with Anthropic's AI went out of business after it was convinced to give away items for free and sell a video game console.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

Legendary architect Frank Lloyd Wright designed the SC Johnson headquarters in Wisconsin, aiming to make a cathedral-like workplace

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Explore chaos in this simulation of two double pendulums, where small differences in the release angles produce wildly different outcomes.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.