Memory disorders disrupt the brain's ability to make, store, or recall memories

Dementia describes progressive memory issues that impact daily activities

Although Alzheimer's disease is sometimes thought of synonymously with dementia, there are multiple types of dementia, which manifest in memory loss and other symptoms that make it challenging to perform daily tasks. These types include Lewy Body dementia, vascular dementia, and frontotemporal dementia. Parkinson's disease is not a form of dementia, but this movement disorder can sometimes develop into issues with memory and a formal diagnosis of dementia.

Learn the differences between mild cognitive impairment and age-associated memory loss

Mild cognitive impairment is a condition in which people experience more thinking and memory problems than expected for their age. It's often associated with depression and anxiety. Daily routines, writing things down, and healthy lifestyle choices can help cope with the condition, but there's no cure. The condition elevates the risk of developing dementia and Alzheimer's.

ADHD impairs working memory and limits the ability to form long-term memories

While ADHD is most often recognized for producing struggles with attention and organization, these executive functions are critical for capturing the data that creates memories in the brain. Breaking data into pieces, or chunking, helps address these struggles.

Why vascular dementia develops

This type of dementia, the second most common form after Alzheimer's, develops due to microscopic bleeds and blood vessel blockages in the brain. The condition isn't curable but medications to help with blood clotting and high blood pressure are part of a suite of interventions designed to minimize damage to the brain.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Age, stress, and neurological disorders can prevent memory formation and recall

Neurons transmit signals between one another at sites called synapses. Repeated interactions at these sites improve the efficiency of signal transmissions, making memories involving sensory data associated with those neurons easier to recall. Biochemical factors impacting these synaptic interactions affect memory quality.

Alzheimer's disease is the leading cause of dementia and risks rise after age 65

Read this primer about Alzheimer's disease and learn what factors increase the risk of this form of dementia, including genetics, being a woman, and health conditions, including high blood pressure.

Memory exists as multiple types stored across various brain systems

Memory isn't one uniform function—it's made up of multiple systems, like declarative (facts/events) and non-declarative (skills/habits), which involve different brain areas such as the hippocampus, amygdala, and cerebellum.

Some dementia cases may be linked to microorganisms in the brain

Researchers now know that, much like the gut, the brain is home to an ecosystem of microorganisms—the brain microbiome. While this area of study is still new, some scientists believe 50% of bacteria-caused dementia cases could be treated. (Some users may encounter a paywall.)

Alzheimer's can cause brain shrinkage of between 10% and 30%

While the exact cause of Alzheimer's is debated, the buildup of amyloid plaques and tau protein tangles is instantly recognizable in post-mortem examinations. The atrophy of brain cells caused by this molecular pileup leads to noticeable physical changes, including significant shrinkage in affected brain regions.

The first identification of Alzheimer's was made in 1906

The first case of Alzheimer's disease dates to the early 20th century when Dr. Alois Alzheimer had 51-year-old Auguste Deter as a patient. Deter struggled with sudden memory issues and aggressive, irrational behavior. After Deter's death, Alzheimer examined her brain and found strange collections of molecular pileups.

Can your identity be preserved amid dementia?

Memory loss associated with progressive dementia raises questions about whether a person's identity can be maintained during the disease's progression. One outlook suggests we define ourselves by our social relationships—offering a potentially more humane approach to caring for those with dementia.

How family members disappeared into dementia

This narrative feature describes one family's troubling experience with frontotemporal dementia, or FTD, which emerges in the prime of adult life — as young as 40, in some cases — and degrades the brain's ability to plan, organize, express language, understand social cues, and exercise judgment.

Researchers use the brain's ability to edit memories to explore memory deletion

Scientists have successfully implanted false memories in mice after studying how the editing process works in the brain. Beyond potentially deleting memories in those with PTSD, upcoming research may allow clinicians to forecast the onset of neurodegenerative diseases.

When to see a doctor over memory lapses

Memory includes various, distinct functions, like working memory (storing information temporarily) and procedural memory (your body's ability to perform a task unconsciously). Forgetting a word or losing your keys can feel like red flag memory lapses, but they are, in fact, language or attention problems, not memory ones. However, a lapse on top of stress, lack of sleep, chronic dysfunction, or an injury may be a red flag to see your doctor.

The brain consolidates memories during sleep

During sleep, the brain appears to process memories from the day and encode them into long-term storage. At the same time, the brain prunes old memories out of the brain that are no longer useful. Understanding this process also sheds light a various neurodegenerative diseases.

Long-term memory formation may not need short-term memory

New research shows that long-term memories can still develop even when short-term memory formation is blocked, suggesting the brain uses separate pathways for short- and long-term memory. This discovery could help scientists open new avenues for treating memory loss in diseases like Alzheimer’s.

How Alzheimer's caregivers get pulled into their loved one's reality

Caregivers, most often children and spouses, do not just witness a family member's cognitive decline—they also often become drawn into it, navigating a world in which the typical rules of time, order, or logical continuity may not apply.

How alcohol rewires your brain

Alcohol doesn't just make you tipsy—it rewires your brain chemistry in real time. It slows your brain with GABA, spikes dopamine to make you feel unstoppable, and blocks glutamate so you can't form memories. That mix explains everything from slurred speech to blackouts … and brutal hangovers.

Repeated head injuries can lead to CTE and early dementia

Chronic traumatic encephalopathy is a progressive neurodegenerative disease caused by repeated trauma to the head. The condition has become a particular concern in sports like football and soccer, from youth to professional leagues, where repeated low-level concussive events are likely.

Physiological muscle memory allows us to quickly regain lost musculature

The term "muscle memory" is most often associated with the neurological kind, which involves the development of strong and efficient neural pathways in the brain and spine. Physiological muscle memory also slows the loss of muscle mass, with both types affected by genetics and diet.

Measles infection can cause long-term immune system “amnesia”

The measles virus attacks the body's immune system, including preying on T and B cells in the lymphatic system. These cells hold memories of past infections, which can be degraded as the virus destroys them. This leaves patients susceptible to other infections for a year or longer.

Common genetic disorders

As research continues, it's clear that disease and genetics go hand in hand. Here's a selection of 50 National Human Genome Research Institute (NHGRI) articles providing basic information on genetic, orphan, and rare diseases caused by mutations in DNA sequences, whether inherited from parents or brought about by outside factors.

Always forget a face? The science of face-blindness

Faces and names don't always go together in some people's minds. While everyone forgets other peoples's names occasion, people diagnosed with prosopagnosia can't recognize faces, much less names. Even friends can family members can appear to be strangers. This article covers the diagnosis and issues attendant to prosopagnosia and its sufferers.

Left versus right brain strokes vary significantly in long-term effects

Due to the high complexity of the brain, the aftereffects of a stroke can have widely different manifestations, ranging from minor temporary impairments to rapid death. Whether a stroke results in paralysis, speech impairments, loss of bodily function, or death will depend on whether it occurs in the left or right hemispheres or the brain stem.

Trauma is a primary risk factor for substance use disorder later in life

Studies indicate 75% of people with substance use disorder have experienced at least one traumatic experience in their life. These experiences alter brain function, leading to heightened stress and emotional pain. Substances offer temporary relief, but this often results in dependency.

Researchers believe the brain consolidates memories, processes emotions, and plans for the future during dream states

About 12.5% of US adults experience a phobia in their lifetime, a diagnosis that hinges on the intense fear interfering with daily life and persisting for at least six months.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Salvador Dalí believed he was his own dead brother, who had died nine months before he was born

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Marburg virus, related to Ebola, is also extremely deadly, and has no available vaccine.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Some renewable energy sources may weaken the resiliency of electric grids by removing outage buffers provided by coal- and natural gas-fired plants, which provide the system with more time to find a new power source if a plant goes down.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Learn more about the history of fireworks, which dates back to an accidental invention during an alchemist's quest for information about immortality.

Use this tool to calculate the dollar value of your parental mental load, from meal planning to coordinating after-school care, then see resources that help generate solutions.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

Volcanoes 'die' when their supply of magma runs out, if they are shifted away from their underlying magma reservoir, or if they get clogged by collapsing or their magma cooling back into rock.

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

The Mona Lisa's celebrity status and repeated restorations have obscured what made the painting so revolutionary for its time

Corals are themselves not coral reefs—the term refers to the tiny marine invertebrates that build the rigid reef.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

The US first hosted the World Cup in 1994, a tournament that lives in soccer infamy for its poor planning and the murder of Colombian player Andres Escobar, who'd accidentally scored on his own net.