Age, stress, and neurological disorders can prevent memory formation and recall

Synaptic plasticity allows neurons to communicate effectively and form memories

First proposed in 1949, synaptic plasticity allows the brain to adjust communication strength between neurons. This ability to change synaptic strength—either briefly or over long periods—is essential for learning and memory, with long-term synaptic plasticity forming the basis of how memories are stored.

Neurons send signals through electrical impulses and chemical messengers

By converting electrical signals into chemical messages at synapses, neurons allow information to travel throughout the nervous system. With repeated use, synapses grow stronger, enhancing the associations between neurons.

How aging degrades neural functioning in the brain over time

Aging affects the brain perhaps more than any other organ in the body. Throughout life, the brain experiences radical shifts in the number of neurons, synaptic connections between neurons, and hormone levels that regulate our mood and processing.

Consistency and emotional engagement can improve the formation of memories

While sleep lets the brain re-trigger neurons associated with our experiences to cement them in long-term memory, repeating actions, like storing one's keys in the same location, can mimic these benefits. Emotionally charged memories are often ruminated upon, improving their future recall.

Memory disorders disrupt the brain's ability to make, store, or recall memories

These disorders stem from reversible issues like vitamin deficiencies or irreversible causes such as stroke or dementia. Only one type of dementia—familial Alzheimer’s disease—is directly inherited and accounts for about 20% of Alzheimer’s cases.

Exercise releases chemicals that enhance cognitive function

Neurotransmitters like dopamine, serotonin, and norepinephrine, along with increased brain-derived neurotrophic factor levels, enhance a wide range of brain functions. New research demonstrates a direct link between movement and numerous cognitive benefits, including memory, learning, and stress resilience.

The brain consolidates memories during sleep

During sleep, the brain appears to process memories from the day and encode them into long-term storage. At the same time, the brain prunes old memories out of the brain that are no longer useful. Understanding this process also sheds light a various neurodegenerative diseases.

What sleep loss does to the brain

Proteins in the brain perform various critical functions, such as helping neurotransmitters function or enabling electrical activity in the organ. These proteins must fold in specific ways to perform their duties, similar to paper airplanes. Sleep deprivation contributes to the gathering of misfolded proteins that aren't shaped correctly for their roles and so accumulate in undesired spaces, such as in the gaps between neurons.

Grief rewires the human brain

The human brain handles stress and emotional traumas similarly. In response to the emotional stress of a situation like the death of a loved one, divorce, or abuse, the brain may strengthen or weaken connections between nerves to form new neural connections. Over time, chronic stress can diminish brainpower, reducing overall nerve growth and memory to shift resources to enable elevated fear responses and enable humans to survive.

False memories can form during recall when new information is incorporated

Often formed due to suggestion and misinformation, false memories can lead to serious consequences, such as wrongful convictions. The time between an event and recalling it affects one's susceptibility to false memories.

Researchers use the brain's ability to edit memories to explore memory deletion

Scientists have successfully implanted false memories in mice after studying how the editing process works in the brain. Beyond potentially deleting memories in those with PTSD, upcoming research may allow clinicians to forecast the onset of neurodegenerative diseases.

Memory is a complex narrative constructed from real and imagined experiences

Memories start with perception and are processed in the hippocampus. Different types of memories use different brain regions, and episodic memory, which is involved in recalling one's life events, is more susceptible to decay than semantic memory, which is involved in general information.

Long-term memory issues among West Nile survivors may be from immune response, not virus

Rodent research suggests that long-term neurological complications such as fatigue, weakness, difficulty walking, and memory loss, may be due to the immune system systematically destroying parts of neurons in the brain in response to the infection, rather than due to viral infection itself.

Long-term memory formation may not need short-term memory

New research shows that long-term memories can still develop even when short-term memory formation is blocked, suggesting the brain uses separate pathways for short- and long-term memory. This discovery could help scientists open new avenues for treating memory loss in diseases like Alzheimer’s.

Remylination is a huge focus for treatment—especially among older adults

Our ability to build new myelin sheaths for nerves degrades with age. There have been research advances boosting cells that support these processes and clear away debris from degraded myelin, but not yet any medications to boost myelination itself, which would aid nerve signaling and preserve nerve function.

Neural rhythms shape how we move, focus, remember, and interact with the world

Millions of neurons in the brain produce rhythmic electrical signals, or brain waves, that guide physical movement and help form and store memories. Researchers also use these rhythms to create brain-computer interfaces, letting people control devices using only their thoughts.

Chronic drug use can cause neurological changes in the brain

Neuroscientist Judy Grisel breaks down the biology of addiction, examining how drugs hijack the brain’s natural reward system and create lasting neural changes. The physiological and neurological impacts of chronic drug use require a multifaceted treatment approach.

The "reminiscence bump" causes memories from adolescence to last

Research shows that the "reminiscence bump" phenomenon, which applies to memories formed between the ages of 10 and 30, contributes to songs from those ages triggering the most intense nostalgia. This may be due to biological and hormonal changes enhancing memory effectiveness during adolescence.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Physiological muscle memory allows us to quickly regain lost musculature

The term "muscle memory" is most often associated with the neurological kind, which involves the development of strong and efficient neural pathways in the brain and spine. Physiological muscle memory also slows the loss of muscle mass, with both types affected by genetics and diet.

How depression affects the brain

Treatment for depression has historically hinged on the theory that the condition was caused by underactive or abnormal neurotransmitters, specifically serotonin and norepinephrine. This four-minute video by Yale Medicine details how these neurotransmitters didn't explain the symptoms of depression but, two other neurotransmitters involved in regulating mood and emotion did. GABA and glutamate, some of the brain's most plentiful neurotransmitters, may possibly be the source of depressive symptoms.

Sleep disorders can exacerbate neurological and other health conditions

Brain regions that control sleep sit adjacent to those that regulate the autonomic nervous system, which controls involuntary bodily functions like heart and breathing rates. These neighbors influence each other, meaning poor sleep can impair or negatively impact the ANS, further disturbing sleep.

Sclerosis is the technical term for the lesions or plaques that form without myelin

In the absence of myelin, the body forms scar tissue called sclerosis. That scar tissue hampers nerve's abilities to transmit nerve impulses, essentially acting as a roadblock to speedy communication.

Watch how your nervous system's efforts to process silence can contribute to tinnitus

Cochlear cells can be damaged in numerous ways, including aging or exposure to loud noise. If enough cells die, the auditory system can become less sensitive, prompting the brain to compensate by amplifying sound, which is likely to contribute to tinnitus.

How science explains déjà vu

Take a fun look at the science explaining the odd experience of déjà vu, which some theories suggest is actually a sign of a healthy brain.

Some data links schizophrenia to older paternal age and birth complications

Yet both associations are not yet considered firm enough to definitively be causative. Schizophrenia is a multi-causal syndrome and a mixture of factors, including genetics, are widely believed to be behind its development.

Researchers believe the brain consolidates memories, processes emotions, and plans for the future during dream states

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Ebola infects and disables immune cells, triggering a cascade of events that leads to small blood clots throughout the body, weakening blood vessels and interrupting blood flow to key organs.

Some renewable energy sources may weaken the resiliency of electric grids by removing outage buffers provided by coal- and natural gas-fired plants, which provide the system with more time to find a new power source if a plant goes down.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

About 12.5% of US adults experience a phobia in their lifetime, a diagnosis that hinges on the intense fear interfering with daily life and persisting for at least six months.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Firework or sparkler burns, even if they cover a relatively small area of skin, can significantly affect our range of motion.

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

Coral reefs get their colors from zooxanthellae—microorganisms that line corals' digestive tracts and provide them with sugars in exchange for a home within this protective tissue.

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

Graffiti dates back to at least ancient Pompeii, where citizens scrawled messages to one another on public walls