How family members disappeared into dementia

How frontotemporal dementia changes your personality

Significant changes in personality later in life are often attributed to psychological factors. But Dr. Bruce Miller, long-time researcher of FTD, argues this shift is most often attributable to changes in the brain.

What it feels like to live with dementia

This nine-minute short film attempts to answer what it feels like to fade into dementia, as memory, motor skills, and cognition steadily decline. This award-winning short film follows Jos, a married father who worked in hospitality, as he sinks into ,"what feels like a single day. Or is it years?"

Alzheimer's as a family disease: When children become "parents"

Kitty Eisele's 81-year-old dad went missing while on a snowy, four-hour drive from Minneapolis to Iowa City. It was the first emergency that spelled out the danger of her dad's dementia diagnosis—and captures how Alzheimer’s impacts entire families, with the influx of responsibility that comes with caregiving.

How Alzheimer's disease affected one family as symptoms progressed

News program 60 Minutes interviewed a couple navigating aging and Alzheimer's over a 10-year period to illustrate the effects of the disease on their lives.

How neurodegeneration happens, the underlying disease process of dementia

Dementia symptoms may vary between individuals, and may include mood changes, difficulty walking, speaking, and memory problems. It can progress over many years, occurring due to progressive damage to nerve cells in the brain. This degradation may happen for myriad reasons, and its triggers are under investigation.

Can your identity be preserved amid dementia?

Memory loss associated with progressive dementia raises questions about whether a person's identity can be maintained during the disease's progression. One outlook suggests we define ourselves by our social relationships—offering a potentially more humane approach to caring for those with dementia.

Five to ten percent of Alzheimer's cases are early-onset

Early-onset Alzheimer’s typically emerges around 40 to 50 years of age, with devastating effects. This video follows Brian, diagnosed with the disease at age 54, as he travels the country as an advocate for research and discusses the progressive mental fog of Alzheimer’s.

After a dementia diagnosis, it's important to plan ahead but also savor the moment

The next steps after a diagnosis include taking lifestyle steps to slow disease progression and completing legal paperwork about long-term medical preferences. It's also important to appreciate the moments and days ahead and find humor in them, when possible. (Some users may encounter a paywall.)

The deadly genetic disease that steals shut-eye

Few are haunted by fatal familial insomnia. This neurodegenerative disease is typically carried through bloodlines via genetic mutation of the prion protein gene, forcing the body to create abnormal and pathological protein variations that can corrupt normal versions. This article follows a musician as they attempt to come to terms with the FFI plaguing their family (and, possibly, their future).

America's financial burden from dementia in 2025 was $781 billion

That figure, calculated by researchers at the University of Southern California, includes medical and long-term care costs, unpaid family and friend caretaking, lost productivity for patients and their families, and the economic loss in quality of life for patients and their families. In 2025, they estimate there were 5.6 million people living with dementia.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

How reading and writing can lower dementia risk by almost 40%

Research published in 2026 that tracked almost 2,000 older adults for an average of nearly eight years suggests that lifelong exposure to intellectual stimulation, such as learning a language, reading, and writing, can lower dementia risk by as much as 40%.

Repeated head injuries can lead to CTE and early dementia

Chronic traumatic encephalopathy is a progressive neurodegenerative disease caused by repeated trauma to the head. The condition has become a particular concern in sports like football and soccer, from youth to professional leagues, where repeated low-level concussive events are likely.

A brain scientist's experience with a stroke

What happens when a leading brain scientist has a stroke of her own? Dr. Jill Bolte Taylor recounts moment by moment watching her brain function slow and then cease, followed by a prolonged recovery. Through this experience, she details what she learned about the phenomenon of stroke and how it has impacted her research ever since.

'FAST': An acronym to remember stroke symptoms to look for

The primary factor in surviving a stroke is how quickly one gets the appropriate medical treatment. “FAST” refers to the four most noticeable symptoms of a stroke: face-dropping ("F"), arm weakness ("A"), speech difficulty ("S"), and "time to call 911" ("T").

Aging explained with Dr. Nick Golinvaux

Aging is more than wrinkles and gray hair—it’s a gradual decline in cellular function. Over time, DNA damage, telomere shortening, and mitochondrial inefficiency contribute to weaker bones, slower memory, and reduced vitality. While aging is inevitable, regular exercise, quality sleep, and stress management maintain health and extend one’s years.

Always forget a face? The science of face-blindness

Faces and names don't always go together in some people's minds. While everyone forgets other peoples's names occasion, people diagnosed with prosopagnosia can't recognize faces, much less names. Even friends can family members can appear to be strangers. This article covers the diagnosis and issues attendant to prosopagnosia and its sufferers.

A family's yearslong poisoning

Over 14 years, a southern Indian family slowly lost six members, several of whom were found foaming at their mouths. Upon the third death, a post-mortem examination was requested, revealing cyanide had been ingested, though it was ruled as self-inflicted. Several will edits and three deaths later, relatives turned a critical eye toward Joliyamma "Jolly" Joseph, who had married into the family and been present at each death.

ADHD impairs working memory and limits the ability to form long-term memories

While ADHD is most often recognized for producing struggles with attention and organization, these executive functions are critical for capturing the data that creates memories in the brain. Breaking data into pieces, or chunking, helps address these struggles.

Listen to how gaps in schizophrenia care helped to lead to a murder

Michael Laudor attended Yale, succumbed to schizophrenia, and killed his pregnant fiancée. The podcast, which includes a long but moving interview with Laudor's friend Jonathan Rosen, uses the tragedy to frame how America's approach to severe mental illness has fallen short.

What happened to thousands of teens from the 1990s?

Scientists followed thousands of teenagers from 1997 into their 30s, cataloging their adverse experiences along the way via nearly three decades of interviews. Teens who grew up dealing with poverty, uninvolved parents, and other childhood stressors and traumas racked up an ACE score. These adverse childhood experiences have lifelong impacts on one's health, relationships, financial security, and "pretty much everything else," making them more likely to suffer premature death.

1 in 15 adults over age 40 experience phantom odors

This phenomenon was measured in a 2018 study that examined the prevalence and risk factors for phantom odor perception. Older adults were less likely to experience these phantom odors as they age, just as their overall sense of smell declines. Women are more likely than men to perceive phantom odors.

Prolonged Grief Disorder has certain recognizable risk factors

This official diagnosis is characterized by intense, daily symptoms of grief a year after the loss of a loved one among adults and faster—around at least six months—for kids and teens. Factors that put people at increased risk of this disorder include being single, attachment anxiety, violent or unnatural death, low education, low income, and multiple losses, among others.

Terminal lucidity is the phenomenon of sudden, heightened mental clarity when on the verge of death

The "Let's Talk Near Death" podcast explores phenomena around the end of life, inviting guests to recount their own experiences. This episode focuses on the phenomenon known as "terminal lucidity," where patients experience clarity, vivid memory recall, and more, typically following a heart attack, stroke, or other trauma.

In China, deepfaking a dead loved one has become a growing industry

Digital replicas of the deceased provide individuals with another way to process grief in a culture with long-standing traditions of communicating with ancestors. The emotional and ethical implications of "digital immortality" are complicated further by cases of actors impersonating deceased relatives during deepfake video calls to hide their deaths.

Roughly 90% of generational wealth dries up by the third generation, epitomized by the phrase 'shirtsleeves to shirtsleeves in three generations'

Several factors can influence how wealth is passed down from generation to generation, but some of the main threats are mismanagement, estate taxes, and an expanding family tree.

About 12.5% of US adults experience a phobia in their lifetime, a diagnosis that hinges on the intense fear interfering with daily life and persisting for at least six months.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

Researchers believe the brain consolidates memories, processes emotions, and plans for the future during dream states

In 1945, Surrealist artist Salvador Dalí and legendary animator Walt Disney began collaborating on a short film that was not completed until 2003, years after both men had died.

See how Ebola tore through Guinea, Sierra Leone, and Liberia in 2014-2016.

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

A researcher recently discovered an interview from 1967 between groundbreaking journalist Joan Didion and the Grateful Dead, years before the band became an institution.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

Frank Lloyd Wright's houses are historically hard to sell because they're old, subject to local landmark commissions, and often unfashionable

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

Use this tool to calculate the dollar value of your parental mental load, from meal planning to coordinating after-school care, then see resources that help generate solutions.

Discover the catastrophic consequences of a failure of the US electrical grid—something that is more likely than many Americans think.

Firework or sparkler burns, even if they cover a relatively small area of skin, can significantly affect our range of motion.

Domino's Pizza's 30-minute delivery guarantee was responsible for the chain's 1980s surge, but it was discontinued after the company was found liable for delivery driver accidents.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Netflix profits when you're not watching, and its movies are designed that way—read a detail-rich critical essay exposing lesser-known Netflix takes

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.

While the first exchange-traded fund (a 'basket' of different assets that can be bought and sold on a stock exchange) in the US only launched in 1993, the global ETF market has grown to more than $10T in the short time since.

In 2009, the nation was gripped by the story of a missing young boy who was believed to be floating over Colorado in a homemade balloon, until it was revealed that he was at home the whole time.

Explore the archaeological treasures of Pompeii, the city buried under volcanic ash when Mount Vesuvius erupted in 79 CE.

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.