How frontotemporal dementia changes your personality

How family members disappeared into dementia

This narrative feature describes one family's troubling experience with frontotemporal dementia, or FTD, which emerges in the prime of adult life — as young as 40, in some cases — and degrades the brain's ability to plan, organize, express language, understand social cues, and exercise judgment.

Alzheimer's brain changes may begin years before symptoms appear

The debilitating disorder degrades cognitive abilities. Its symptoms may start with subtle memory issues, but by the time patients notice any changes, neural changes may already be progressing, such as the accumulation of beta-amyloid plaques between neurons and tau protein tangles within them.

Can your identity be preserved amid dementia?

Memory loss associated with progressive dementia raises questions about whether a person's identity can be maintained during the disease's progression. One outlook suggests we define ourselves by our social relationships—offering a potentially more humane approach to caring for those with dementia.

How neurodegeneration happens, the underlying disease process of dementia

Dementia symptoms may vary between individuals, and may include mood changes, difficulty walking, speaking, and memory problems. It can progress over many years, occurring due to progressive damage to nerve cells in the brain. This degradation may happen for myriad reasons, and its triggers are under investigation.

These areas of the brain are hard-hit in depression—but the changes are reversible

Depressed brains can have certain characteristic changes, including an overactive amygdala, reduced hippocampus size, and changes to the thalamus and neuromodulating chemicals in the brain.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Brain training game creates long-lasting changes in the brain that may help protect against dementia

Findings published in 2026 that tracked more than 2,000 older adults, examining dementia onset and completion of cognitive speed training activities, provide some of the strongest evidence yet that cognitive training games can help protect against dementia. Participants who underwent speed training and received booster sessions had a 25% reduction in the risk of dementia diagnosis compared with the control group.

How burnout alters your brain

Stress is a normal part of everyday life, and it’s not necessarily all bad. But chronic stress—the kind that leads to burnout—can change the size and functioning of parts of your brain. It can alter the ability to make new brain cells and memories and even potentially modify your DNA.

Dementia describes progressive memory issues that impact daily activities

Although Alzheimer's disease is sometimes thought of synonymously with dementia, there are multiple types of dementia, which manifest in memory loss and other symptoms that make it challenging to perform daily tasks. These types include Lewy Body dementia, vascular dementia, and frontotemporal dementia. Parkinson's disease is not a form of dementia, but this movement disorder can sometimes develop into issues with memory and a formal diagnosis of dementia.

Schizophrenia symptoms, like psychosis, often first emerge among young adults

A combination of genetics, significant brain changes to the frontal cortex, and hormonal changes during young adulthood—late teens to early 30s—result in schizophrenic symptoms often showing up during this period. The stress of life changes at that age may also be a contributing factor.

Can the gut microbiome influence personality?

New research suggests the bacteria in our gut—through the hormones and molecules they produce—can contribute to conditions ranging from depression to anxiety, and much more. The findings suggest diets have a direct impact on mental health and may lead to new therapies.

Like fingerprints, brain anatomy is unique too

Researchers have discovered that a combination of experiences and genetic factors shape the anatomy of the human brain. They found even quick experiences affect the brain’s genetic makeup, which—over time—means every person develops a completely unique brain anatomy. While brain imaging could be used to identify individuals, it remains much more expensive than fingerprinting for now. Read to found out more about this study from the University of Zurich.

Left versus right brain strokes vary significantly in long-term effects

Due to the high complexity of the brain, the aftereffects of a stroke can have widely different manifestations, ranging from minor temporary impairments to rapid death. Whether a stroke results in paralysis, speech impairments, loss of bodily function, or death will depend on whether it occurs in the left or right hemispheres or the brain stem.

Fruit fly experiments show personality emerges, in part, from genetic factors

A 2025 study revealed that fruit flies exhibit unique behavioral preferences, akin to personalities, which could be artificially selected for when breeding to modify behavioral variability. This variability can be adaptive in unpredictable environments.

Hearing loss is linked with brain volume reductions

The brain looks different as a result of hearing loss, with reductions in brain volume overall and in specific areas, and these changes are hypothesized to impact cognition. Exactly why hearing loss alters cognition is an active area of research, but theories include that the elevated cognitive load of straining to hear affects brain power available for thinking and memory and that hearing loss leads to social isolation which boosts dementia risk.

Psychedelics set off a flurry of brain activity that may permanently alter it

The brain seems to experience a sharp increase in communication between areas that generally don't interact. New research suggests a thin, sheet-like gray matter structure tucked deep within the brain, between the insular cortex and striatum, may be the key to this change. The area is centrally located and home to many of the receptors that psychedelics target, potentially rewiring the brain and rewriting thought patterns.

Menopause and perimenopause symptoms may affect both the mind and body

Women going through these aging transitions may experience some common physical and mental symptoms to varying degrees, including hot flashes, bladder control issues, brain fog, and vaginal dryness. This article dives into some of the most common symptoms women might expect during perimenopause, plus what they can do to relieve them.

Personality tests use the Barnum effect, where vague flattery makes generic descriptions feel specific

A 1949 experiment by psychologist Bertram Forer showed that students rated identical, generic personality profiles as highly personalized. This is the same approach used in horoscopes, Myers-Briggs personality types, and fortune tellers. Even well-resourced tests like Myers-Briggs show poor test-retest reliability, with up to half of retakers getting different results.

NDEs typically change people's outlooks drastically and can prompt depression

The phenomena are regularly categorized as hallucinations, but some specialists are interested in their psychological nuances. Many survivors report feeling less anxiety about death, though some surveys show the experiences can increase physiological sensitivities.

PTSD is a long-lasting mental disorder linked to past traumatic events

Posttraumatic stress disorder is a mental health condition arising from traumatic events with four key symptoms: intrusive memories, avoidance behavior, negative moods and thoughts, and changes in emotional and physical reactions.

Traumatic brain injury is a leading cause of brain death—and TBIs are trending up

Traumatic brain injury-related deaths have generally increased between 2000 and 2023, growing from roughly 49,000 to more than 68,000 in 2023. Firearm-related suicide is the most common cause of TBI-related deaths in the US, according to the Centers for Disease Control and Prevention. People also experience TBIs from falls, motor vehicle crashes, or assaults.

Visualizing shifts in emotional performance in film

Computational scientists were curious: has the intensity of emotional expression in films changed over the decades? Using their sophisticated analytical models, the researchers discovered actors' emotional performance has declined in intensity over time. They believe the close-up shots common in contemporary film-making allows actors to be more subtle in their performance. Check out the main takeaways and charts with this unusual study.

When to see a doctor over memory lapses

Memory includes various, distinct functions, like working memory (storing information temporarily) and procedural memory (your body's ability to perform a task unconsciously). Forgetting a word or losing your keys can feel like red flag memory lapses, but they are, in fact, language or attention problems, not memory ones. However, a lapse on top of stress, lack of sleep, chronic dysfunction, or an injury may be a red flag to see your doctor.

Core memories are a popularized version of autobiographical memories

Core memories are not limited to five key events, do not individually shape personality traits, and are not formed in childhood. Our strongest memories are formed in early adulthood, but are as prone to error as any other memory.

Brain conditions and surgery can cause some individuals to feel no fear

Fear is a survival mechanism that originates in the brain's amygdala, triggering the body's fight-or-flight response. However, in modern society, without the same natural dangers, fear can lead to anxiety and mental health issues when unnecessarily triggered. Understanding individuals without fear may help identify new methods to treat anxiety disorders.

Fame can trigger addictive, drug-like highs in the brain

Differences in the type of fame, such as movie stardom, sports, and internet virality, can produce varying degrees of dependence on individuals based on their age and background. Some individuals—particularly children—can develop drug-seeking behavior as they pursue continuous dopamine spikes if they lack an existing sense of fulfillment from elsewhere.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

About 12.5% of US adults experience a phobia in their lifetime, a diagnosis that hinges on the intense fear interfering with daily life and persisting for at least six months.

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Use this calculator to find the dollar value of your mental load, from meal planning to coordinating after-school care for your children.

Firework or sparkler burns, even if they cover a relatively small area of skin, can significantly affect our range of motion.

Cultural norms about how to handle the bodies of loved ones in communities in West Africa have hampered Ebola responses.

Chaos theory—informally known as the butterfly effect—is the reason why weather forecasts are presented with probabilities rather than certainties.

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

Frank Lloyd Wright's houses are historically hard to sell because they're old, subject to local landmark commissions, and often unfashionable

Warren Buffett's former professor Benjamin Graham is known as the 'father of value investing,' a strategy in which investors seek to buy stocks trading below their intrinsic worth.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

The first steps to rebuilding your credit score include getting to know exactly what's on your credit report and figuring out how far you are from the '700 club,' or 'good score' range.

The identity of the Tank Man in the iconic photo from the 1989 Tiananmen Square protests remains unknown and was possibly killed.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

Domino's Pizza's 30-minute delivery guarantee was responsible for the chain's 1980s surge, but it was discontinued after the company was found liable for delivery driver accidents.

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.