Scientists are studying dying patients' brain activity in the final moments of life

Brain activity goes into overdrive around the point of death

Recent studies suggest increased electrical activity in the brain during and after clinical death could be responsible for near-death experiences. Both high-frequency gamma waves (linked to perception and attention) and low-frequency beta waves (related to focus and concentration) increased and became more synchronized across multiple brain regions, potentially resulting in a near-death state of heightened consciousness.

What happens in a dying brain?

Near-death experiences usually happen during death or on the border of life and death when a person isn't understood to be conscious. This article details the science of what's going on with the brain during NDEs.

Watch this 2021 video demonstrating a full brain death examination

This video and accompanying article in the peer-reviewed New England Journal of Medicine show the then-standard steps of a full brain death examination—demonstrating the process on a medical dummy to search for pain, blinking, eye movement, cough, gagging, or other forms of responsiveness. (May need to sign up for a free account to view.)

Four in 10 CPR patients report consciousness not captured by standard measures

A recent study found people revived by CPR after cardiac arrest reported they experienced some amount of consciousness during clinical death, suggesting our brains are capable of thought and memory for significantly longer after death than previously thought.

Pig brain cellular activity was restarted hours after death in study published in 2019

Yale University scientists restored basic cellular activity and circulatory function in pig brains about four hours after death with a synthetic cocktail of preservatives and nutrients. This work— which didn't restart electricity activity in the brain or consciousness—could help advance future human stroke and brain injury treatments.

The evolution of dream science—from interpretation to advanced brain imaging

In the mid-1900s, dream scientists would tape study participants' eyes open, wait for them to fall asleep, and attempt to influence their dreams by shaking, tickling, and more. Now, advanced techniques like MRIs have shed new light on what’s happening in the brain as we sleep.

Studies of psychedelic use may help shed light on the nature of consciousness

The nature of consciousness—what it is, where it comes from, and how it manifests as moment-to-moment experience—remains under debate by scientists. Recent studies show psychedelics were found to boost low-frequency brain signals known as delta waves, a behavior also seen during dream states.

A brain scientist's experience with a stroke

What happens when a leading brain scientist has a stroke of her own? Dr. Jill Bolte Taylor recounts moment by moment watching her brain function slow and then cease, followed by a prolonged recovery. Through this experience, she details what she learned about the phenomenon of stroke and how it has impacted her research ever since.

Thanatology is the study of death and dying

Watch this video exploring the evolution in how researchers are studying and understanding death in the context of recent scientific research. CPR to restart hearts, ventilators, and other discoveries have challenged the way we think of death and scientifically upended the idea of death as a single moment.

'Donation after circulatory death' is on the rise

This occurs when a patient in a coma is on life support and family members agree to donate the organs. Watch this video about a 2025 New York Times investigation that identified 12 instances across nine states of bungled or premature attempts to retrieve organs from people whose families had authorized withdrawal of life support.

The neuroscience of heartbreak

An analysis of functional MRIs revealed a difficult fact: the active brain areas of people experiencing heartbreak were very similar to those actively in love. This is a major reason why people in the middle of rejection can't accept the reality of their loss. This article breaks down the various changes in neurotransmitters and neural pathways for those enduring that universal experience, heartbreak.

Your brain appears to age in five distinct stages

Analysis of brain scans from about 4,000 people has helped scientists identify five major stages of our brain's maturation from birth to death. The pattern of connections inside our brains seem to shift, on average, at ages 9, 32, 66 and 83. (Some readers may experience a paywall.)

Schizophrenia is being studied with pea-sized 'mini-brains'

Brain organoid research is enabling researchers to study distinct electrical firing patterns associated with schizophrenia. These "mini-brains" that are constructed in the lab from patients' cells could lead to better diagnosis approaches and drug development.

The ‘paranormal activity’ lab at the University of Virginia

Near-death experiences aren’t the only thing they study at Greyson’s Division of Perceptual Studies. The lab approaches a host of “paranormal” phenomena—like past lives and out-of-body experiences—with the same academic rigor as the physics or economics department.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Neural rhythms shape how we move, focus, remember, and interact with the world

Millions of neurons in the brain produce rhythmic electrical signals, or brain waves, that guide physical movement and help form and store memories. Researchers also use these rhythms to create brain-computer interfaces, letting people control devices using only their thoughts.

Everything scientists could learn by looking at your skull

Our skulls are all unique, but they also share characteristics across groups of people. In the absence of fingerprints, forensic scientists can learn a lot about you just from your skull.

Deep brain stimulation helps manage movement in patients with neurological disorders

DBS is a surgical procedure that uses implanted electrodes to send electrical signals to targeted areas in the brain, interrupting abnormal neural activity. It may be implemented when medications lose effectiveness or cause disruptive side effects.

Brain training game creates long-lasting changes in the brain that may help protect against dementia

Findings published in 2026 that tracked more than 2,000 older adults, examining dementia onset and completion of cognitive speed training activities, provide some of the strongest evidence yet that cognitive training games can help protect against dementia. Participants who underwent speed training and received booster sessions had a 25% reduction in the risk of dementia diagnosis compared with the control group.

Anesthetics slow brain activity by promoting inhibitory neurotransmitters

Drugs like propofol and isoflurane increase activity at the GABA receptor, which opens chloride channels. These ions enter neurons and hyperpolarize them, making them less likely to fire. Dexmedetomidine instead blocks norepinephrine receptors in the brainstem to sedate patients.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

Researchers believe the brain consolidates memories, processes emotions, and plans for the future during dream states

The heat death of the universe will mark the perceptive end of time

Under this scenario, all matter and energy will be scattered as far out as possible, with no stars left to produce measurable light between objects. With no way of observing changes or increasing the disorder of the universe further, events could not be distinguished from one another, and time would lose meaning.

Using deep learning to analyze tumors

The explosive growth of life sciences data is driving artificial intelligence methods to gain traction in biology and medicine — including cancer research.

Some founders of quantum mechanics thought consciousness could influence phenomena

Since quantum systems exist as a superposition of states before producing a definitive outcome, some quantum pioneers wondered if the act of conscious observation was what collapsed the wave function of possibilities into one state.

The disease no one survives (yet)

Creutzfeldt-Jakob disease is currently incurable and can cause one's death within months of symptoms appearing. It involves misfolded proteins that, for some reason yet unknown to science, aren't cleared by the brain as typical and instead trigger similar proteins to misfold. These malformed major prion proteins—prion being a portmanteau of protein and infection—clump inside nerve cells, blocking signals crucial to processes ranging from speaking to organ function.

After a dementia diagnosis, it's important to plan ahead but also savor the moment

The next steps after a diagnosis include taking lifestyle steps to slow disease progression and completing legal paperwork about long-term medical preferences. It's also important to appreciate the moments and days ahead and find humor in them, when possible. (Some users may encounter a paywall.)

Stephen Hawking's final message

Famous cosmologist Stephen Hawking—who lived for half a century after being diagnosed with Lou Gehrig's disease—delivered a final speech just before he died in 2018. In the video, Hawking talks about the importance of science and reason in...

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

Watch what the Ebola virus does inside our cells and organs in order to spread and survive.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

Neutron stars, the remains of some massive stars after they explode in a supernova, are the densest directly observable objects in the universe.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

According to the physics of black holes, our 4D reality may be a hologram—a projection of information coded on a 2D surface on the edge of the universe.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Explore the animals that populate the depths of the ocean, from fish and coral in the first few hundred feet, all the way down to the bottom of the Mariana Trench.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

In 1945, Surrealist artist Salvador Dalí and legendary animator Walt Disney began collaborating on a short film that was not completed until 2003, years after both men had died.

This site reaches millions of visitors who are tired of AI chatbots and seeking human connection. Pretend to be an AI chatbot and ask questions, provide answers, and draw for people in real time.

In 2018, 26-year-old missionary John Allen Chau was killed by tribesmen after attempting to reach and evangelize on India's isolated North Sentinel Island

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

Volcanoes 'die' when their supply of magma runs out, if they are shifted away from their underlying magma reservoir, or if they get clogged by collapsing or their magma cooling back into rock.

Explore chaos in this simulation of two double pendulums, where small differences in the release angles produce wildly different outcomes.

Netflix profits when you're not watching, and its movies are designed that way—read a detail-rich critical essay exposing lesser-known Netflix takes

44% of Americans say they pray at least once a day—discover how your state's religiosity stacks up against the rest of the country.