Your brain appears to age in five distinct stages

How aging degrades neural functioning in the brain over time

Aging affects the brain perhaps more than any other organ in the body. Throughout life, the brain experiences radical shifts in the number of neurons, synaptic connections between neurons, and hormone levels that regulate our mood and processing.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

The evolution of the human brain

The human brain, in all its staggering complexity, is the product of millions of years of evolution. Read on to find out about brain size and intelligence, language and brain development, and more.

Visualize the difference between a healthy brain and one with Alzheimer's

The brain has three main parts—the cerebrum, brain stem, and cerebellum—each combining to control the entirety of the body's operations. Alzheimer's progressively deteriorates the circuitry in these structures, resulting in what we see as the symptoms of the disease.

A pregnant woman's brain sheds gray matter, perhaps explaining 'baby brain'

The brain areas involved in processing information and emotions decrease by an average of almost 5% during pregnancy. Researchers discovered in a 2025 study that this mostly temporary change—the brain hadn't fully returned to its normal size six months after pregnancy—seems to be associated with self-reported improved bonding and less hostility toward the child postpartum.

Like fingerprints, brain anatomy is unique too

Researchers have discovered that a combination of experiences and genetic factors shape the anatomy of the human brain. They found even quick experiences affect the brain’s genetic makeup, which—over time—means every person develops a completely unique brain anatomy. While brain imaging could be used to identify individuals, it remains much more expensive than fingerprinting for now. Read to found out more about this study from the University of Zurich.

Strength training appears to make for a healthier, youthful-looking brain

A study from 2025 links having higher amounts of muscle with a more youthful-looking brain age. Scientists analyzed data from more than 1,100 healthy adults around their mid-50s after they underwent full-body MRIs, comparing muscle, fat, and brain age appearances from the scans.Their findings link strength training and controlling visceral fat with improved brain health. The research didn't tease apart why this benefit occurs.

Chronological versus biological age

Science has come to understand different types of aging. What we call age is simply the number of years since birth, or chronological age. At the cellular level, biological aging happens at different rates for different people, and explains why some seem to age more quickly (or slowly).

Five to ten percent of Alzheimer's cases are early-onset

Early-onset Alzheimer’s typically emerges around 40 to 50 years of age, with devastating effects. This video follows Brian, diagnosed with the disease at age 54, as he travels the country as an advocate for research and discusses the progressive mental fog of Alzheimer’s.

Super-agers: seniors 80 and above with the memory ability of people in their 50s

Studies show the number one indicator of whether someone is a "super-ager" is not diet or genetics, but the extent of their social relationships. Moreover, scans reveal noticeable physical differences in certain parts of the brain in patients with extensive social networks.

Understanding the stages of sleep

Do you have trouble keeping the different stages of sleep straight and organized in your mind? Us too. Sometimes it helps to have a straightforward listing of what each stage is and why it’s important. Look no further than this resource from Lumen. It is a basic outline of the four stages of the sleep cycle, along with the brainwaves and attributes that characterize each. If you’re brave enough, test yourself on the built-in quiz!

Why do humans have such long childhoods?

Humans have over twice as long childhoods than other animals with similar lifespans like whales and elephants. A human child can grow for nearly 20 years before they become a reproducing adult. Researchers believe there's a connection between long childhoods and human's unusually large brain size, though the science is not totally clear. Dive into what scientists know here.

Scientists are studying dying patients' brain activity in the final moments of life

In the final moments of life there are distinctive bursts of coordinated neural activity. Researchers are interested in parsing that data to better understand the dying process and also exploring how this data relates to our understanding of consciousness.

MS can damage the brain up to 7 years before symptoms appear

Recent research scouring blood samples from 134 people with MS, both before and after their diagnosis, found that about seven years before these patients were diagnosed, there was a spike in a protein called myelin oligodendrocyte glycoprotein—indicating disease-associated damage to the protective myelin around nerve fibers.

The dreaming brain, as understood by scientists

Technology has advanced to where the seemingly separate fields of psychology and neuroscience are asking the same questions about dreams, such as whether they're more closely related to perception or visualization. Some field-intersecting findings include research that shows people with impaired face perception don't dream of faces, those with brain legion-related cognition difficulties deal with similar issues in dreams, and children's dreams change in parallel to their cognitive development.

Take a quiz to discover your brain care score

Each year, nearly 800,000 Americans have a stroke. With such a high occurrence rate, you may be asking yourself what you could do now to prevent a future stroke. Researchers at Harvard collaborated to answer this question by coming up with a "Brain Care" scoring system. Take the quiz to learn the quality of your brain health today and pick up helpful insights to lower your risk of stroke and dementia well into the future.

Schizophrenia symptoms, like psychosis, often first emerge among young adults

A combination of genetics, significant brain changes to the frontal cortex, and hormonal changes during young adulthood—late teens to early 30s—result in schizophrenic symptoms often showing up during this period. The stress of life changes at that age may also be a contributing factor.

The human brain only uses 5% more energy during active tasks versus resting

Despite only being 2% of the weight of a human body, the average adult brain consumes 20% of its energy, with the majority of it spent on maintaining homeostasis—the stable equilibrium conditions of temperature, acidity, blood sugar, and other properties in the body. For infants, the consumption is closer to 50%.

Some dementia cases may be linked to microorganisms in the brain

Researchers now know that, much like the gut, the brain is home to an ecosystem of microorganisms—the brain microbiome. While this area of study is still new, some scientists believe 50% of bacteria-caused dementia cases could be treated. (Some users may encounter a paywall.)

Researchers believe the brain consolidates memories, processes emotions, and plans for the future during dream states

'Susan's Brain': what happens to the brain during addiction

This engaging animation from Harvard Online breaks down the neuroscience of addiction through the story of “Susan’s brain,” demonstrating how addictive substances hijack normal reward pathways. Through clear visual metaphors and approachable narration, it explains complex brain chemistry in understandable terms.

How the brain processes a calendar year

When most of us picture a calendar year, we have a foggy image in our minds of the months, in rough, calendar-like grids. But for some folks, that picture is a whole lot more clear. Around 1 percent of the population has a strange ability known as "calendar synaesthesia," which means they're able to visualize in crisp detail an elaborate calendar of the months of the year. Learn how it works here.

How our sense of taste evolves as we age

Kids are hardwired to prefer sweets over greens, with sweetness a shorthand for calorie-rich and bitter flavor warning of potentially noxious plants. This holds true even in the womb, where fetuses have been seen via ultrasound scans grimacing as their hosts consume kale capsules. As they age into double digits and beyond, their taste cells and sense of smell diminish, leading to broader and less sensitive palates.

The five stages of grief—and what to do when yours doesn't follow this model

The "five stages of grief" is a well-established process used by many to move through periods of mourning. Grief is notoriously difficult to manage, and such procedures help move people forward. Only, what happens if your experience doesn't match the model at all? This podcast episode explores one researcher's unique approach to processing her own grief.

See how faces on magazine covers have changed over time

This piece examined an archive of Time magazine containing 3,389 issues ranging from 1923 to 2014, focusing on 327,322 faces from the archive. Read what the researchers learned.

The "reminiscence bump" causes memories from adolescence to last

Research shows that the "reminiscence bump" phenomenon, which applies to memories formed between the ages of 10 and 30, contributes to songs from those ages triggering the most intense nostalgia. This may be due to biological and hormonal changes enhancing memory effectiveness during adolescence.

As of 2025, the internet is entering its fourth phase, with three more to go

Since the inception of the internet as a tool for connecting teams of researchers, technological and infrastructure advancements have progressively increased connectivity. Connections between computers, mobile devices, all devices, and now AI agents will be succeeded by an internet that integrates perception and the senses toward an eventual quantum internet.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

See how each of the more than two million known species relates to each other—and to common ancestors—in this zoomable tree of life.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

See the most iconic photos from four decades of LIFE magazine

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

Hear 50 years of iconic hip-hop samples, the genre's foundational looped tracks

Use this tool to calculate the dollar value of your parental mental load, from meal planning to coordinating after-school care, then see resources that help generate solutions.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

According to the physics of black holes, our 4D reality may be a hologram—a projection of information coded on a 2D surface on the edge of the universe.

US housing costs have risen by roughly 175% between 1991 and 2026—but a growing number of Gen Zers are becoming homeowners anyway. In 2025, 4% of homebuyers were Gen Z, up from 3% the year before.

Trace how the Bill of Rights, inspired by centuries of political theory, took shape between 1774 and 1789.

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Search a massive database of over 4 decades of clues from the TV quiz show 'Jeopardy!'

In 1963, a basement renovation in Turkey revealed a passageway to a hidden, multilevel underground city that once housed as many as 20,000 people

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

The first steps to rebuilding your credit score include getting to know exactly what's on your credit report and figuring out how far you are from the '700 club,' or 'good score' range.