Stem cells can reboot the ability of cells to repair themselves

Stem cells have the ability to self-renew

Stem cells have remarkable potential for new medical therapies. But to understand what makes stem cells so special, you must understand exactly what they are, and what they’re capable of doing. This page offers an accessible introduction to stem cell biology and their unique properties.

How do stem cells actually work?

Stem cells are unspecialized cells that can develop into various cell types while also making exact replicas of themselves. This amazing ability has made stem cells a candidate to treat a wide variety of diseases and conditions—though the vast majority of potential therapies remain in the research stage.

There are three types of stem cells, each with different properties

Embryonic stem cells are "blank slates" that can change into any other type of cell. Adult stem cells can become specialized cells to replenish the supply or repair injury, while induced pluripotent cells are "reset" by scientists and used in clinical and medical applications.

How to turn any cell of the body into a stem cell

Scientists have developed techniques allowing them to 'reprogram' any cell in the body into an induced pluripotent stem (iPS) cell, which can be used to create either more stem cells or specialized cells for use in experimental medical treatments. This page gives readers a brief introduction to the history of iPS cells, what researchers are studying with iPS cells, and challenges associated with iPS research.

A Nobel laureate discuss whether stem cells can extend lifespan

Listen to Nobel laureate Shinya Yamanaka discuss the potential of induced pluripotent stem cells to extend human lifespan. By reprogramming adult cells into embryonic-like stem cells, scientists might be able to rejuvenate tissues and treat age-related diseases—though ethical and safety concerns remain.

Stem cell therapies show promise in treating spinal injuries

Researchers have long hoped to use stem cells in regenerative medicine to help patients with spinal cord injuries restore sensation and movement. A 2024 clinical trial illustrates how stem cells derived from patients' fat tissue could help spur the creation of new cells in the spinal cord.

Multiple new research paths may lead to slowing (or even reversing) aging

Aging has always been inevitable, but fasting, epigenetic reprogramming, and parabiosis seem to help people stay young. By studying centenarians, memory, and even the humble roundworm, scientists are looking for the genetic basis to live not just a long life, but a healthy one.

New blood cells are created by hematopoietic stem cells

Blood is made up of several cells with various functions and short lifespans, so the body must have a constant supply of replacements. These replacements are created by hematopoietic stem cells, rare cells that live in bone marrow and can regenerate themselves and blood cells.

The scandal that rocked stem cell research

In 2014, a Japanese research group published a paper suggesting ordinary cells could be reverted to pluripotent stem cells by subjecting them to external stressors. The results generated interest but could never be replicated. The lead researcher was accused of fraud, and the group’s supervisor committed suicide.

'Cells Making Cells': 'Science Sam' discusses the potential of stem cells

In this episode of the Ologies podcast, host Alie Ward picks the brain of science communicator Samantha Yammine—whose PhD work focused on neural stem cells. The conversation covers everything from the earliest days of stem cell research to what the future of stem cell therapies may look like.

Cells can last in the human body from days to a person's entire life

Despite claims that a person's body replaces itself every seven to 10 years, the rate at which cells die and are replaced varies by cell type. Gastrointestinal cells that line the digestive tract and stomach last only a few days, while some heart muscle cells and most neurons are around from birth until death.

Remylination is a huge focus for treatment—especially among older adults

Our ability to build new myelin sheaths for nerves degrades with age. There have been research advances boosting cells that support these processes and clear away debris from degraded myelin, but not yet any medications to boost myelination itself, which would aid nerve signaling and preserve nerve function.

Cellular aging and deterioration leads to tissue (and overall) aging

Cells are the building blocks of life, forming tissues and organs that keep our bodies working. As we age, cellular changes have progressive consequences on both the structure and function of our organs. This article examines this complex relationship as it relates to the incremental changes associated with aging.

Mice were able to regenerate retinal cells in the lab—a breakthrough for mammals

Using gene therapy, a team of Korean researchers has enabled retinal regeneration in mice by blocking the intercellular transfer of a single inhibitory protein. This 2025 finding creates a new potential direction for treating retinal diseases. The work, which is still in animal studies, is projected to enter early-stage clinical trials in the next few years.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

Most cells undergo programmed, controlled death

In the average adult human, apoptosis occurs in 50 billion to 70 billion cells daily when proteins managing a cell's life cycle send signals that the cell is damaged, causing it to break apart into smaller pieces that are consumed by white blood cells. The consumption prevents damage from spreading via cell division.

'Endoevolution' refers to the Darwinian selection happening continually inside us

The term, coined by Roxanne Khamsi in her 2026 book "Beyond Inheritance: Our Ever-Mutating Cells and a New Understanding of Health" describes the idea that evolution does not just occur across generations of humans. Instead, mutated cells continuously compete with healthy ones in our bodies, with implications for our tissues and health. Khamsi says these autocorrections are essentially natural gene therapy. 

Homology-directed repair is the DNA repair method used by cells

Environmental factors like X-ray exposure may break a strand of DNA, but cells can use a sister strand to patch the damage. Scientists exploit this system by introducing custom DNA templates, which cells use instead to make repairs.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

Explore how cells respond to signals from their environment

In "Dropping Signals," users can drag stimuli, such as hormones and light, into various cellular environments to observe cellular responses. These include changing their shape, enabling the transport of chemicals into or out of the cell via the cell membrane, or dividing to compensate for surrounding damaged cells.

Microtears in muscles from exercise cause fibers to grow back larger

Placing muscle under increased load or stress causes damage that requires rest to repair, leading to stronger, more enduring muscle over time. Muscles adapt to such increasing demands by improving their efficiency with approaches that include increasing the number of mitochondria housed in hundreds of thousands of muscle cells.

How medical robots could cure cancer

Medical robots are on the verge of being able to be injected into the body, where they will be responsible for semi-autonomous behavior, such as detecting cancer cells and distributing medication. This six-minute video dives into the science of these nanorobots, which are smaller than blood cells. Applications of these nanobots could range from disease discovery and condition monitoring to tissue repair and artificial blood delivery.

How Nobel Prize-winning research unraveled why the immune system doesn't always attack itself

The 2025 Nobel Prize was awarded to scientists who discovered how immune system soldiers are typically stopped from attacking healthy tissue. The work furthered autoimmune understanding and cancer therapies.

Easy resets for stress reduction

Individual solutions for burnout, often called “self-care,” can be helpful for managing stress. Harvard researcher Aditi Nerurkar’s 2024 book The Five Resets details a road map for burnout recovery. In this interview she suggests, among other tactics, gaining focus on what matters the most in one’s life, taking breaks from both work and the internet, and making time for practices that strengthen the mind-body connection.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Growing EV adoption requires battery management infrastructure

Despite rechargeable batteries' limited life cycle, companies like Spiers New Technologies have developed methods to repair, refurbish, repurpose and recycle these components to minimize environmental waste, lower demand for new critical minerals, and increase electric vehicle lifetimes.

Technologies developed for the ISS have brought benefits to people on Earth

About 93% of water used onboard the International Space Station is recycled through filtration and purification systems that have since been used in regions lacking access to clean water. Treatments to mitigate bone loss and muscle atrophy in astronauts can also help aging adults.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Read about coral reef restoration efforts, from coral IVF and cryopreservation

Researchers have collected coral eggs and sperm from healthy reefs, grown baby corals in lab pools, and released them to help repopulate damaged or lost reefs. Devices such as Coralclip® help attach these corals to existing structures, promoting growth without the use of chemical bonding agents. Corals near extinction can be frozen using liquid nitrogen for future restoration efforts.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

Tattoos remain visible on your skin thanks to immune cells called macrophages

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Learn how monoclonal antibodies, which mimic the body's antibodies, can fight diseases like Ebola.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

Some renewable energy sources may weaken the resiliency of electric grids by removing outage buffers provided by coal- and natural gas-fired plants, which provide the system with more time to find a new power source if a plant goes down.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

The first steps to rebuilding your credit score include getting to know exactly what's on your credit report and figuring out how far you are from the '700 club,' or 'good score' range.

Watch how algorithms can be designed to train themselves and self-improve without human input, to the point where the optimized code is too complex for programmers to understand.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

Coral reefs get their colors from zooxanthellae—microorganisms that line corals' digestive tracts and provide them with sugars in exchange for a home within this protective tissue.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

Long before Major League Baseball began allowing instant replay for balls and strikes, an umpire reluctantly used the technology to determine whether a hit was a home run, a move that inadvertently ushered in a new era for the sport.

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

Learn more about the history of fireworks, which dates back to an accidental invention during an alchemist's quest for information about immortality.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.