Two-thirds of soldier deaths during the war were due to disease

The Civil War was the deadliest conflict in American history

Between 1861 and 1865, an estimated 620,000 to 750,000 soldiers died from battle and disease—more than in all other US wars combined.

Yellow fever sidelined more US troops than enemy fire during the Spanish-American War

The disease, transmitted by the Aedes aegypti mosquito, sickened more than 2,000 soldiers. Fewer than 400 American soldiers died in the 1898 war.

The Civil War introduced many technological advances to both society and warfare

The conflict accelerated innovations—including railroads, telegraphs, ironclad ships, and mass-produced weapons—while advances in photography, medicine, and manufacturing transformed how Americans communicated, healed, and built after the war.

Penicillin slashed battlefield pneumonia deaths during World War II

Before antibiotics, bacterial pneumonia killed about 18% of infected soldiers in World War I. By World War II, penicillin cut that death rate to less than 1%.

Cholera was called the 'Blue Death'

In the mid-1800s—when John Snow identified cholera in London—the disease was known simply as the "Blue Death." That's because blood would thicken in patients' veins when they were struggling with extreme dehydration. As a result, their skin would turn a blueish hue as their blood was starved of oxygen.

Detailing the horrific conditions of life in the trenches

What was it like to live and fight in a trench during World War I? If you were on the German side you might have bunkers, electricity, and other basic comforts. If you were on the British and French side the conditions have been described as muddy and "horrific". Find out how unpleasant trench warfare was and how it affected WWI soldiers.

Hundreds of women secretly joined the Union and Confederate armies during the war

Hear the story of women who disguised themselves as men to enlist in both Union and Confederate armies—serving as soldiers, medics, and spies.

1 in 4 people around the world don't have access to clean water

Poor water sanitation puts people at risk of acquiring this diarrheal infection. Cholera infections are on the rise due to extreme weather events and conflict. In recent years there have been cholera outbreaks in locations that hadn't seen the disease in many years, including Haiti.

Roughly 25,000 workers died building the canal

For each mile of canal that was built, 500 workers lost their lives. The threats came from multiple fronts: mudslides, floods, earthquakes and disease-carrying mosquitoes. Workplace accidents became so common that artificial limb manufacturers competed for contracts with the canal builders.

Alexander the Great, Rudyard Kipling, and more may have died from food poisoning

Though it is hard to prove decades or centuries after their deaths, some researchers suspect that food poisoning killed a variety of historical figures, including US President Zachary Taylor in 1850: Some researchers believe he may have consumed food contaminated with *Salmonella*.

The US Army massacred close to 300 Lakota men, women, and children at Wounded Knee in 1890

Fearing the Ghost Dance—a spiritual movement spreading across starving reservations—the Army surrounded a Lakota encampment at Wounded Knee Creek, South Dakota. When a shot was fired during an attempted disarmament, it sparked chaos, and soldiers killed nearly 300 people.

Sepsis is the leading cause of death in hospitals

Sepsis is the result of an overly aggressive immune system trying to combat infection, triggering inflammation throughout the body. After it begins, each passing hour increases the risk of death by 4% to 9%, and an estimated 350,000 people die from the condition in the US each year.

Europeans' arrival to America brought disease to Indigenous populations

Indigenous people lived in the Americas for centuries before the arrival of the first Europeans in the 15th century. Their arrival was disastrous for Native tribes; in addition to being enslaved and losing their land, they had no natural immunity to the diseases brought by colonists. Eventually, up to 95% of the Native American population was killed by illnesses including typhus, chickenpox, and cholera, an event now known as the Great Dying.

Death taxes have helped fund wars since the 1860s

Death taxes date back to 700 BCE and were used in Ancient Rome and Ancient Egypt. In the US, they've been used to finance wars since the Civil War, and have been levied on both the estate and beneficiary. The estate tax created during WWI to help finance war efforts is still in effect today.

The Union victory at Gettysburg marked a major turning point in the war

Fought July 1-3, 1863, the Battle of Gettysburg ended the Confederate invasion of the North. While the Union lost nearly 23,000 troops, its victory in one of America's most famous battles shifted the war's momentum decisively toward the North.

The history of germ theory, which explains that illnesses are caused by microorganisms

For centuries, the miasma theory, which held that illnesses were caused by clouds of "bad air" produced by decaying organic matter, was the accepted explanation for the spread of disease. The development of microscopes and the subsequent technology to isolate bacteria and test disease spread in mice greatly contributed to contagionists overturning miasmatists.

Abraham Lincoln received only 40% of the popular vote in the 1860 election

Lincoln's 1860 victory came entirely from Northern and Western states, as his name was excluded from most Southern ballots. The outcome highlighted the deep divisions and regional polarization in the country.

How did segregation in the US affect blood donations?

When the US established its first nationwide network of blood banks in 1941 with the hopes of restoring the dwindling reserves of military members, it was quick to emphasize blood donated by Black Americans wouldn't coat the veins of white servicemen. Historians say this policy was meant to appease white Southerners who believed Black blood was inferior to their own.This policy was leaked to the press that same year.

Variola: the second-deadliest virus on Earth

Because it was declared eradicated in 1980, many forget smallpox is one of history's deadliest diseases—in its final century, it's estimated to have claimed 500 million lives. This 11-minute video from production studio Kurzgesagt takes a look at...

Marriages are more at risk when the woman is sick

A study tracking 25,000 copies over 18 years revealed marriages tend to end in divorce more often when the woman is sick. Conversely, men's health issues do not impact divorce rates. Researchers noted that increased depression, potentially as a result of financial dependence, contributes to the disparity. Generally, most marriages do not end when a spouse becomes sick.

Sickle cell trait can put people at elevated risk of heat-related illness

This hereditary blood disorder affects the shape and function of red blood cells. A US military study found that among recruits the incidence rate of exertional heat-related illness was 48% higher among those who had sickle cell trait as compared to those without. Easing into intense exercise and gradually increasing exertional frequency and intensity is recommended.

Dinosaurs suffered from cancer, arthritis, and infections seen in modern animals

Using CT scans and advanced pathology techniques, paleopathologists have identified respiratory illnesses, malignant osteosarcoma, and other diseases in dinosaurs. The research has helped show how many of these ailments are not exclusively modern phenomena.

Cultural norms about how to handle the bodies of loved ones have hampered Ebola responses in West Africa

Awareness of local burial and grieving traditions eventually helped healthcare workers fight the spread of the virus. As healthcare workers and burial teams altered their procedures during the 2014 West African Ebola outbreak, and as community leaders pressed people to adapt traditional ceremonies, the spread of Ebola began to slow.

How a worm helped give the southern US its reputation

"The germ of laziness" that blanketed the southern US for centuries with unshakable fatigue, brain fog, and distended bellies paired with emaciated frames was actually a worm. This parasitic worm lives in the gut, where it can stay up to five years, laying up to 10,000 eggs daily. Hundreds of millions of people worldwide continue to suffer from hookworm infections, often obtained by walking barefoot across infected soil.

The Third Amendment bars the forced housing of soldiers in private homes

The amendment was designed to address a specific grievance of the Colonies and remains the only Bill of Rights provision that has never been directly tested by a Supreme Court ruling on its merits.

Cultural norms about how to handle the bodies of loved ones in communities in West Africa have hampered Ebola responses.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Explore an interactive map of battles from the American Revolution, along with detailed summaries of each engagement

11 people died from firework injuries in the US in 2024.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

The Russia-Ukraine conflict is the largest ground war in Europe since World War II in terms of casualties, forces mobilized, and displacement of civilians.

Many legends about George Washington, including his supposed wooden teeth and the story of cutting down the cherry tree, lack evidence.

Abraham Lincoln was almost assassinated weeks before his inauguration as he traveled from Illinois to DC through Baltimore in 1861; it took two independent claims for Lincoln to be convinced the threat was real

During the French Revolution, a botanist's letter asking about "dear Rhus" (poison ivy) was intercepted, leading authorities to suspect he was conspiring with the Russians.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Mark Twain spent decades feuding with the US Postal Service, convinced its costs and regulations were bureaucratic overreach.

Despite being favored by 87% of Americans, Congress does not have term limits.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

The boiling temperature of water decreases with increasing elevation because the molecules need less energy to overcome the lower atmospheric pressure associated with thinner air.

Roughly 43 million US borrowers owe roughly $1.7T in student debt, the second-largest source of consumer debt behind mortgages.

See how Budweiser's famous Clydesdales spend their days at Warm Springs Ranch, where roughly 70 to 80 of the beer brand's giant horses can be found at any given time.

In 2025, four executives from large tech companies were given positions in the US Army Reserves—including Palantir Chief Technology Officer Shyam Sankar, which reinforced Palantir's ties with the US military and its role as a leading defense partner.

The Beatles' US label rejected the band's first two singles, 'Please Please Me' and 'From Me to You,' with one executive calling the band 'dead in the water.'

In 1945, Surrealist artist Salvador Dalí and legendary animator Walt Disney began collaborating on a short film that was not completed until 2003, years after both men had died.