Research studies can be conducted inside or outside of living samples

IVF procedures fertilize eggs outside the body in a laboratory dish

In vitro fertilization is a complex and expensive set of procedures that potential parents dealing with infertility or genetic disorders may turn to when other methods are unavailable. IVF births account for 2% to 3% of all live births in the US annually.

Model organisms like yeast, mice, and flies help scientists decode the human body

Some species are used to quickly study the effects of human diseases and treatments because they are short-lived and have similar systems to those found in humans. Bacteria, like E. coli, have been used as human proxies given their rapid growth and ease of genetic manipulability.

Bioluminescent reaction enzymes are often used in biomedical research

Near-infrared luciferase systems allow researchers to image and analyze cellular activity in living animals because they penetrate tissue more deeply than visible light. This provides a means of studying gene expression and protein interactions without harming the animals.

De-extinction techniques create new species from existing organisms

Rather than recovering a genetic sample of a lost species and editing it with that of living creature—as has been depicted in science fiction—scientists begin with living cells from close genetic relatives and use tools like CRISPR to swap in extinct versions of specific traits to create new hybrid species.

View a breakdown of bioremediation strategies, divided into onsite and offsite options

Depending on the contamination's complexity, in situ—onsite—options may be preferred and can include supplying oxygen or nutrients into the existing soil to accelerate the microbial breakdown already present in the environment. Ex-situ methods instead displace contamination for treatment away from the environment and may be used for volatile chemicals that require isolation, though this displacement can also spread contaminants if spilled.

Advance genetic research by playing these scientific video games

Computers produce so much information that researchers can’t properly analyze all the data produced, and the overload can also lead computers to make mistakes. Researchers are increasingly turning to citizen scientists—members of the public who are willing to volunteer—to help them make sense of data when computers can’t. This article details a few of the ways you can contribute to genetics research by playing video games.

Organoids: 3D organs grown from stem cells in the lab

An organoid is a three-dimensional construct composed of multiple cell types that originate from stem cells that can simulate the architecture and functionality of native organs. One big benefit of these lab-grown organs is that drug candidates can be tested in model systems without needing live patients.

Despite privacy risks, scientists are using DNA in the air to assess ecosystem health

While DNA in soil and water samples has long been used for such analyses, airborne DNA is being incorporated into such efforts to monitor individual species abundance, detect invasive species, measure biodiversity, and determine the success of conservation actions. Future work may include detecting attacks from biological weapons.

Scientists are experimenting with ways to probe the multiverse theory

Researchers are simulating vacuum bubbles—the theorized starting points of universes—using quantum computers, digital models, and exotic lab setups to study how they form, expand, and possibly collide. One experiment aims to "blow" artificial universe-like bubbles inside ultra-cold quantum gases, potentially capturing real-time glimpses of cosmic birth processes in a lab.

How do brain scans work?

There’s only one thing in our solar system sophisticated enough to study itself: the human brain. But this self-investigation is challenging because a living brain is shielded by skull, swaddled in tissue, and made up of billions of tiny cells. How do we study living brains without harming their owners? Two experts explain how the various techniques like EEGs, fMRIs, and PETs work in this TedEd talk.

Biohacking can include everything from vitamins to brain implants

The growing field of biohacking hopes to help people work with their bodies to achieve health and longevity goals. Some claims go beyond current science, promising to help biohackers avoid cancer or cure heart disease, and much of the evidence supporting "biohacks" stems from subjective self-reports rather than clinical trials.

Explore how cells respond to signals from their environment

In "Dropping Signals," users can drag stimuli, such as hormones and light, into various cellular environments to observe cellular responses. These include changing their shape, enabling the transport of chemicals into or out of the cell via the cell membrane, or dividing to compensate for surrounding damaged cells.

Each scientific study adds incremental knowledge to existing understanding

On its own, no study serves as a source of truth or solves an existing problem indefinitely, though many can be analyzed collectively in a systematic review to build more confidence—the result of more data—in a conclusion. Studies can explore knowledge gaps or test an existing theory, which is always subject to refinement and improvement.

The challenges of trying to study microplastics in microplastic-abundant labs

The presence of microplastics in instruments, surfaces, and air has made accurate measurement of their levels in lab samples difficult, given the high likelihood of contamination. While the use of stainless steel tools in a sealed, clean lab may reduce accidental exposure, existing methods can misidentify biological substances, such as fat, as plastics, further complicating research.

Humans experience the world subjectively. What does that mean for scientific research?

When you close your eyes, do you see static or colorful patterns or an "intrinsic grey" known as Eigengrau in German? This variation of our internal experiences is just the tip of the iceberg, one that scientists are increasingly studying and...

Humans need vitamins, but research is mixed on taking supplements

When an organism needs an organic molecule to survive, but cannot synthesize enough of it itself, that molecule is called a vitamin. Typically, we consume vitamins through food, but many resort to supplements—a common and mostly unregulated practice.

Living donations most commonly involve a kidney or part of a liver

In 2023, more than 6,900 transplants were made possible thanks to living donors. Living donation is when a living person donates an organ or part of an organ—usually one of their two kidneys or part of the liver, since that organ can regenerate in a healthy person. Much more rarely, living donors donate other organs. Living donations often occur when someone wants to ensure a loved one has certainty that they will quickly receive a needed organ.

Challenges for synthetic biology

Can engineering approaches tame the complexity and unpredictability of living systems? An exploration of five challenges for the field and how they might be resolved.

Why scientists are making robot insects

Insects have much to teach us about flying, jumping, moving quickly, and more. So, roboticists are studying how insects do the ridiculous things they do, like walk on water or jump fifty times their body height, to inform their design and engineering of a new slate of robots: tiny ones. Learn the future of this type of robot with this fascinating video with insights into both insects and robots.

What conditions can be treated with stem cells?

Stem cell research is a global enterprise, and much of the work is being done in Europe. This page gives readers a good sense of the medical conditions stem cell researchers in Europe focus on, and the specific research challenges they address. This page also offers links to in-depth information about many of the research projects.

Invasivorism is a form of ethical eating focused on eating invasive species

The culinary approach helps combat the growth of invasive species populations by increasing demand for dishes made with them, but some suggest that creating a market for these species may help prolong their presence by moderating control. Some diners have expressed reluctance toward consuming more exotic species, such as nutria—raccoon-sized rodents.

The medical uses of VR

Virtual healthcare simulations are bridging the gap between traditional classroom learning and real clinical experience, improving the safety, effectiveness and efficiency of healthcare services.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Brain studies suggest some animals do dream (sort of)

Studies on sleeping cats, rats, fish, and finches show that their brains fire as if performing actions from waking life. Spiders and insects also have REM-like sleep. Whether these findings indicate that animals dream depends on one's definition of dreaming.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Read the NASA overview of the results of Viking’s biological experiments on Mars

Three experiments on the Viking 1 and 2 landers searched for signs of metabolic activity in soil samples, indicating the presence of microorganisms. No definitive evidence of life was found in any experiment or lander imaging.

Six of history's most unethical human experiments, from deliberate flu exposure to withholding syphilis treatment

Some of the progress made in mental health treatment, vaccines, blood transfusions, and more came about before the advent of consent and ethics committees, resulting in serious physical and psychological harm that participants in studies were not even anticipating.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Scientists testing how climate change affects plants found, in a years-long simulation study, that poison ivy grew 70% faster with the resulting extra carbon dioxide.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

Explore what it's like inside a patient isolation unit, used in situations such as treating a patient or suspected patient with Ebola.

Watch how algorithms can be designed to train themselves and self-improve without human input, to the point where the optimized code is too complex for programmers to understand.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Explore the known asteroids, comets, and spacecraft involved in asteroid studies within our solar system with 'Eyes on Asteroids,' a 3D visualization from NASA.

Massive 3D printers have been used to build homes by stacking layers of 'concrete toothpaste,' a fire-resistant material that effectively insulates against outside noise.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

Venture capital is a form of funding provided to early-stage companies with high growth potential, typically in exchange for an equity (or ownership) stake

Play the role of a student in a game where you try to navigate college and remain debt-free, selecting different income levels, high school experience, race, ethnicity, and more.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

Netflix profits when you're not watching, and its movies are designed that way—read a detail-rich critical essay exposing lesser-known Netflix takes

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

Long before Major League Baseball began allowing instant replay for balls and strikes, an umpire reluctantly used the technology to determine whether a hit was a home run, a move that inadvertently ushered in a new era for the sport.

Corals are themselves not coral reefs—the term refers to the tiny marine invertebrates that build the rigid reef.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.