Advance genetic research by playing these scientific video games

How do genetics work?

Perhaps you have your mother’s hair or your grandfather’s eyes. How did you get these traits and not others? Learn how genetics work in this online video game.

The Human Genome Project spawned numerous spinoff genetics projects

The Human Genome Project led to the development of techniques later applied to projects in microbial and plant biology, epigenomics, environmental and cancer genomes, and more. In the spirit of the HGP, data from these projects has been made freely available to develop new technologies.

The lack of diversity in DNA databases limits their applications

European ancestry dominates genetic research, hindering the usage of genetic databases for precision medicine for other groups, including African Americans, who face higher health risks due to genetic variants. Many Indigenous communities have also resisted genetic research due to past exploitation. (Some readers may experience a paywall.)

Genetic tests aren't always actionable, which is one reason genetic counselors are so vital

This podcast interview with a Harvard Medical School professor focused on cancer genetics and prevention discusses the specifics of genetic testing and insights and the challenges of processing the outcomes of the testing and what may be actionable—or not.

Genetic engineering will change everything forever

Designer babies, the end of diseases, genetically modified humans that never age. Outrageous things that used to be science fiction are suddenly becoming reality. As scientists increasingly understand how specific genes cause disease, the possibility of engineering our genes to not only "fix" problems but enhance our natural ability grows.

Dispose of invading viruses while learning about the CRISPR immune system

In this free, easy-to-play game, defend the city of Bacterium by playing the role of Cris Perotein. As you play, you'll learn microbiology and the workings of the mechanisms that CRISPR uses to protect bacteria. (desktop recommended)

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Common genetic disorders

As research continues, it's clear that disease and genetics go hand in hand. Here's a selection of 50 National Human Genome Research Institute (NHGRI) articles providing basic information on genetic, orphan, and rare diseases caused by mutations in DNA sequences, whether inherited from parents or brought about by outside factors.

Video games are helping to preserve cultural heritage sites, further archaeological study

When Carmen Sandiego swept onto the video game scene in 1985, the deluxe version of the game included historic photographs from National Geographic and music from the Smithsonian. Read this article to learn about the overlap between gaming and ancient architecture.

Explore the differences between healthy and cancerous cells using a DNA microarray

In this simulation, you will learn how scientists use microarrays to experiment on thousands of genes at the same time. By determining which genes are on or off, users can identify those that contribute to cancer formation.

Researchers are exploring neural links between Alzheimer's and autism

Recent DNA sequencing and molecular biology studies suggest that similarities in genes, neural circuitry and patterns of disease warrant further exploration to potentially better understand both conditions and how to treat them. (Some users may encounter a paywall.)

Help scientists at LIGO train AI to resolve glitches in observational data

Volunteers are provided with visual representations of signal abnormalities at various frequencies and tasked with categorizing them based on reference examples. Progressing through the tool unlocks more difficult images and additional features. Categorized images will be used to train machine learning algorithms for automated future classification.

Fruit fly experiments helped identify genes responsible for major body development

The insects' fast life cycle and affordability have allowed geneticists to quickly identify which genes are responsible for limbs, eyes, and other body structures by inducing mutations. The same genes may be responsible for different parts of a species' body, such as limb-building genes being responsible for wing pigmentation in butterflies.

Why do people play farming simulation video games?

This article is an anthropological dive into farming simulation video games. Humans began experimenting with agriculture and farming about 12,000 years ago, though it would be another 8,000 years before the practice became a common approach across...

Experience games that explore Nobel Prize-winning work

Inspired by the educators who set laureates on their path, the Nobel Foundation has created a library of interactive activities for the general public. These allow users to make groundbreaking discoveries, showing that such work is accessible to all.

Losing the kids to video games

An estimated 60 million people suffer from internet gaming disorder worldwide, a category created by the World Health Organization in 2018 to help communities support individuals plagued by pathological play. As the world's most-played game of all...

NSF-funded research into matching algorithms improved the success of organ transplants

Investigations in game theory, including concepts focused on creating mutually beneficial partnerships—matching theory—led to the design of computer systems that efficiently matched kidney recipients and live donors, resulting in higher-quality matches. By 2019, these matching algorithms were used for multi-organ exchanges.

Understanding the causes, effects, and prevalence of algorithmic bias

Found in search engines, hiring and college admissions tools, facial recognition systems, and other software, algorithms act on the rules they are programmed with, which may be authored by individuals unaware of their own biases. Algorithms based on limited, incomplete, or inaccurate data are more likely to inherit and propagate existing biases.

DNA computing allows for storage and processing of massive amounts of data

Although costly and less efficient for simpler tasks, as of 2025, DNA could hold 455 exabytes of data with near limitless parallel computation potential in small data centers. Every movie ever made would fit inside the volume of a single sugar cube.

How Anthropic's frontier red team assesses the dangers of its AI tools

The team of researchers deliberately attempts to breach the safeguards in Claude to determine whether the large language model can be used to commit cyberattacks, develop biological weapons, or enable other harmful behavior. Unlike many other red teams, Anthropic shares its findings and how it resolved them publicly to help build transparency and credibility.

Brain training game creates long-lasting changes in the brain that may help protect against dementia

Findings published in 2026 that tracked more than 2,000 older adults, examining dementia onset and completion of cognitive speed training activities, provide some of the strongest evidence yet that cognitive training games can help protect against dementia. Participants who underwent speed training and received booster sessions had a 25% reduction in the risk of dementia diagnosis compared with the control group.

Inside the community movement behind DIY synthetic biology

Margaret Talbot spotlights the rise of DIY biology in community labs, where amateur scientists—often outside formal institutions—create everything from insulin to prosthetic prototypes. These grassroots biohackers challenge traditional science by pursuing open, accessible innovation, raising questions about credibility, ethical oversight, and acceptance by mainstream researchers.

Research studies can be conducted inside or outside of living samples

While "in vitro" experiments occur outside living organisms for cost-effectiveness, "in vivo" experiments take place inside them, providing real-life insights at a higher cost and with increased ethical concerns. Alternatively, "in silico" methods use computational simulations.

Computational and biological systems share fundamental principles, like randomness

Proposed by Alan Turing and John von Neumann, the concept originates from how DNA and computers run by executing encoded instructions in parallel. The advent of AI and the temperature parameter has seen neural networks mimic the randomness of protein encoding.

When you complete a CAPTCHA on a website to prove you are human, you may be unknowingly training algorithms for self-driving cars, whose systems require training data to help identify crosswalks, bicycles, and other outdoor objects.

How do you sequence a genome?

If the genome is made up of microscopic chromosomes, how do scientists actually sequence it? Here's a 5-minute video explaining one of the most common processes.

Large language models struggle to play video games, despite coding them easily

As of 2025, given clear tasks, specific feedback, and test results to learn from, LLMs have been successful at coding simple video games that resemble pre-existing ones. However, given the variety of games, the lack of training datasets, and the need for spatial awareness, which LLMs find challenging, some of these models experience greater difficulty navigating and "winning" games.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Play the role of a student in a game where you try to navigate college and remain debt-free, selecting different income levels, high school experience, race, ethnicity, and more.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

English mathematician Ada Lovelace wrote the first computer algorithm a century before computers existed and hypothesized that computing devices would one day be able to compose music—foreseeing the generative AI systems of today.

A vending machine run with Anthropic's AI went out of business after it was convinced to give away items for free and sell a video game console.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

Search a massive database of over 4 decades of clues from the TV quiz show 'Jeopardy!'

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Fish populations in the Great Barrier Reef have increased after installing waterproof speakers on the ocean floor that played recordings of sounds from healthy coral reefs.

Explore our favorite visualization of the immense scale of space, from an astronaut to the size of the observable universe

Explore the archaeological treasures of Pompeii, the city buried under volcanic ash when Mount Vesuvius erupted in 79 CE.

Children are now three times more likely to say they want to be a YouTuber when they grow up than an astronaut, with some even attending 'YouTube camps' that teach kids how to create content for the platform.

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

Long before Major League Baseball began allowing instant replay for balls and strikes, an umpire reluctantly used the technology to determine whether a hit was a home run, a move that inadvertently ushered in a new era for the sport.

The Brothers Grimm were lawyers before they were storytellers, but became interested in fairy tales as they began investigating how rules and customs had been passed down through cultures.