Inside the community movement behind DIY synthetic biology

Is synbio really cool, really scary, or both?

There’s always been a divide between technology, the inanimate stuff that we build, and biology, the living stuff that nature builds. Synthetic biologists are trying to figure out how to close the gap by building living things.

Synthetic biology transforms cells into custom DNA foundries

At companies like Ginkgo Bioworks, researchers are reprogramming cells to act as workshops that can create custom molecules, such as medicines and fertilizers, by stitching together DNA sequences—often in novel combinations—before inserting them into an organism's genome.

The crypto city home to biohacking experiments

The DIY nature of biohacking gives the work an entrepreneurial feel, as seen by the emergence of community labs, at-home testing kits, and corporation-backed cities that don't necessarily require government-approved testing standards. Próspera, Honduras, created by a business of the same (first) name, was born from legislation that allowed international businesses to shave off a slice of the country to establish their own micronations.

My experience with biohacking

A general approach that employs technology to enhance the functioning of the human body, biohacking enthusiasts are continuously seeking new ways to optimize their performance. Martin Kremmer, an entrepreneur who became interested in the topic after experiencing burnout, explores his own experiences in biohacking his own diet and lifestyle in pursuit of a longer, healthier life.

Challenges for synthetic biology

Can engineering approaches tame the complexity and unpredictability of living systems? An exploration of five challenges for the field and how they might be resolved.

Despite privacy risks, scientists are using DNA in the air to assess ecosystem health

While DNA in soil and water samples has long been used for such analyses, airborne DNA is being incorporated into such efforts to monitor individual species abundance, detect invasive species, measure biodiversity, and determine the success of conservation actions. Future work may include detecting attacks from biological weapons.

The secret lives of cells

Cutting-edge microscopy has revealed previously unseen interactions of biological molecules within their cellular environment, enabling scientists to observe and analyze the molecules in a holistic view. This podcast explains the minute advancements made over the last few decades in observing cells, revealing how scientists have come and what the future holds for the field.

The quest to find natural ways to extend lifespan

Tales of searching for the Fountain of Youth persist. Our modern-day version is marked by promises of pharmaceutical miracles and a proliferation of viral "biohacking" routines. One doctor’s quest to unlock the keys to longevity stimulated much of this renewed fervor, though his ideas are often taken out of context.

The promises and perils of using at-home genetic tests for your health

A primer on genetic testing, personalized medicine, and the promise of pharmacogenomics–the use of genetics to predict an individual's response to a drug.

This scientist treated her own cancer

Virologist Beata Halassy treated her own breast cancer by injecting the tumor with lab-grown viruses. Though this self-treatment worked, it has not been approved for widespread use. Read to learn more about her fascinating experience, and how it has led to conversations about safety and ethics.

Before Dawkins, other biologists proposed the power of mutating ideas

Nobel Prize winner Jacques Monod proposed, “Ideas have retained some of the properties of organisms. Like them, they tend to perpetuate their structure and to breed; they too can fuse, recombine, segregate their content; indeed they too can evolve, and in this evolution selection must surely play an important role.”

Spontaneous metabolism may give clues to origins of life

Read this article to learn more about the discovery that suggests that metabolism could have begun spontaneously on our planet—and why it means that scientists may need to rethink how we define life’s origins. A team of researchers at the...

CRISPR turns 10 years old

When Dr. Jennifer Doudna and colleagues released a paper in 2012 demonstrating the ability to harness the cell's natural immunity machinery to edit DNA, it received little fanfare. A decade later, the gene editing technology has led to innovations in medicine, evolution, and agriculture—and raised profound ethical questions about altering human DNA.

A student researcher working on the Human Genome Project shares their perspective

In a conversation with Ewan Birney, Director of the European Bio-informatics Institute, he discusses what it was like to be a PhD student working on the Human Genome Project in the months before the draft announcement and its impact on him and the field of genetics.

Research studies can be conducted inside or outside of living samples

While "in vitro" experiments occur outside living organisms for cost-effectiveness, "in vivo" experiments take place inside them, providing real-life insights at a higher cost and with increased ethical concerns. Alternatively, "in silico" methods use computational simulations.

Explore an animated list of nine scientific breakthroughs funded by NASA, the NSF, and the NIH

Among the technologies made possible by the National Science Foundation and the National Institutes of Health were the CAPTCHA digital puzzles to block bots from accessing sites, the set of diabetes and obesity drugs that fall under the umbrella of GLP-1 receptor agonists, and various cordless appliances, including the handheld vacuum cleaner. (Some readers may experience a paywall.)

Understanding insulin

Scientists Daniel and Kelly talk with researcher Dr. Katrine Whiteson about diabetes, the history of insulin production, and Dr. Lydia Villa-Komaroff—an essential member of the team who discovered that bacteria could be induced to produce insulin. Listen to discover interesting facts about the life-saving medicine and how it works in the human body.

The ABCs and FAQs on GMOs from the WHO.

GMOs (or genetically modified organisms) are a subject of great debate in the food world…but how come? GMOs are organisms whose genetic materials have been altered in a way that does not occur naturally in order to create a product that has a...

The Buzzcocks' 1975 self-released EP inspired a DIY ethos for punk

Punk sought to dismantle the self-importance of mainstream rock, favoring simple arrangements, short songs, and raw passion over sophistication or expertise. When the Buzzcocks struggled to find a label to release their debut record, “Spiral Scratch,” they took that do-it-yourself approach and applied it to business by releasing it themselves.

According to Bill Nye, science is under threat from an erosion in critical thinking

He states that conducting research online cannot replace consulting with scientific experts who have spent their entire lives intimately studying a field. The former science education show host argues that deepening cynicism towards scientific institutions has been fueled by leaders embracing debunked and unsupported claims.

Superbugs evolve defenses against medication, then share them with neighbors

One reason antibiotic resistance spreads so quickly is that bacteria have multiple mechanisms allowing them to share genetic material. This short video offers a concise explanation for each of these mechanisms, and animation that helps viewers understand how antimicrobial resistance can quickly spread from one organism to another.

English chemist Rosalind Franklin (1920 - 1958) on the importance of science

"Science and everyday life cannot and should not be separated. Science, for me, gives a partial explanation of life."

A Bay Area lab was supplying MLB players with steroids

The Bay Area Laboratory Co-operative, also known as BALCO, began as a modest vitamin shop, but by the 1990s it was at the center of a doping scheme that rocked Major League Baseball and other professional sports.

Activity trackers promise to improve health by forcing us to examine the facts

Explore how modern fitness culture, rooted in capitalist ideals of productivity and control, shapes our perception of health and self-worth. The author blends cultural criticism with personal insight to examine the contradictions of the wellness industry, the rise of wearable tech, and what it means to "optimize" a body.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

How memes create in-groups

Memes can hop offline, inspiring IRL events ranging from planking to shootings. By nature, memes contribute to the formation of in-groups, ones who are privy to meanings that escape content moderators who don't necessarily recognize what's hidden within layers of references.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Watch how algorithms can be designed to train themselves and self-improve without human input, to the point where the optimized code is too complex for programmers to understand.

Massive blooms of microscopic plankton called dinoflagellates produce the neon blue light seen in glowing tides.

Children are now three times more likely to say they want to be a YouTuber when they grow up than an astronaut, with some even attending 'YouTube camps' that teach kids how to create content for the platform.

This site reaches millions of visitors who are tired of AI chatbots and seeking human connection. Pretend to be an AI chatbot and ask questions, provide answers, and draw for people in real time.

Massive 3D printers have been used to build homes by stacking layers of 'concrete toothpaste,' a fire-resistant material that effectively insulates against outside noise.

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

Jimmy Carter signed a 1978 bill that legalized home brewing, a move credited with kick-starting the craft beer industry.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

After NASA's Voyager 1 captured Earth as a single pixel as it left the solar system in 1990, astronomer Carl Sagan used the image to reflect on humanity's fragility and the responsibility to protect 'the only world we've ever known.'

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

'Saturday Night Fever,' the 1977 film that introduced disco to the mainstream, was based on a fabricated magazine story.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Hear 50 years of iconic hip-hop samples, the genre's foundational looped tracks

A researcher recently discovered an interview from 1967 between groundbreaking journalist Joan Didion and the Grateful Dead, years before the band became an institution.

Some researchers have labeled nomophobia, the fear of being without your phone, as 'the phobia of the 21st century.'

During the French Revolution, a botanist's letter asking about "dear Rhus" (poison ivy) was intercepted, leading authorities to suspect he was conspiring with the Russians.