Explore the differences between healthy and cancerous cells using a DNA microarray

Visualize how CRISPR works at the molecular level

CRISPR is a revolutionary gene-editing technology already making a real-world impact in helping to treat several diseases and conditions. This simulation provides a microscopic view to help easily visualize the complex science.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Genetic tests aren't always actionable, which is one reason genetic counselors are so vital

This podcast interview with a Harvard Medical School professor focused on cancer genetics and prevention discusses the specifics of genetic testing and insights and the challenges of processing the outcomes of the testing and what may be actionable—or not.

Using deep learning to analyze tumors

The explosive growth of life sciences data is driving artificial intelligence methods to gain traction in biology and medicine — including cancer research.

Advance genetic research by playing these scientific video games

Computers produce so much information that researchers can’t properly analyze all the data produced, and the overload can also lead computers to make mistakes. Researchers are increasingly turning to citizen scientists—members of the public who are willing to volunteer—to help them make sense of data when computers can’t. This article details a few of the ways you can contribute to genetics research by playing video games.

What is cancer bioengineering?

While new treatments for cancer are under continuous development, researchers are increasingly using engineering principles to find wholly new strategies to combat the disease. Directions include nanoparticle drug delivery, advanced imaging tools, developing new materials to interact with cells, tissue engineering, robotic surgeries, and more. Such interdisciplinary efforts are expected to unlock new tools and therapies beyond traditional drug formulation.

Ancestry testing matches DNA to known genetic variants found in specific ancestries

After a lab receives a person's sample, the DNA is separated into single strands, which are chemically cut into smaller fragments. The fragments are then fed into an array of variants of known origins, and technicians observe if a person's fragments bind to specific variants.

Despite privacy risks, scientists are using DNA in the air to assess ecosystem health

While DNA in soil and water samples has long been used for such analyses, airborne DNA is being incorporated into such efforts to monitor individual species abundance, detect invasive species, measure biodiversity, and determine the success of conservation actions. Future work may include detecting attacks from biological weapons.

Searching for the history of cancer in ancient human bones

Nestled under archaeology lies bioarchaeology, which involves the study of bones, human or animal. This subfield recently birthed another field of study: paleo-oncology. Paleo-oncology looks for cancer and related biomarkers in bioarchaeological remains. This TED article explains how this nascent multidisciplinary field challenges the idea that cancer is modern.

Watch DNA replicate itself before cell division

In the average adult human, between 50 billion and 70 billion cells die daily, requiring them to replicate their genetic instructions before dividing into new cells. This process relies on various proteins to unwind, read, build, and proofread new strands, with error rates of fewer than one per 1 billion nucleotides.

The immune system is in a constant fight against mutations

At the heart of cancerous cells is the development of mutations—an ongoing and continuous process that happens frequently. So why don’t we get cancer immediately? The body’s immune system has developed intricate methods to detect and destroy cancer cells, catching the vast majority before they get the chance to evolve into tumors.

mRNA vaccines alter immune response, not DNA, to combat diseases like cancer

These vaccines—developed using techniques to create COVID vaccines—are now being tested for cancer treatment and have shown improved survival rates in patients with lung cancer. Scientists believe the research involved in developing these vaccines has opened the door to new and effective personalized cancer treatments in the future.

Calculate your risk of developing cancer

Hosted by the National Cancer Institute, this tool provides interactive charts that display the likelihood of dying from various causes—including cancer—based on factors like age, sex, race, and smoking status. By contextualizing cancer risk among other potential health threats, users can create custom charts.

Symptoms of DNA loss may mimic those seen in mushroom poisoning or chemotherapy

Although no organism has ever lost all its DNA, the destroying angel mushroom contains amatoxin, which disrupts DNA transcription and is known to cause death via liver and kidney failure in three days. Doxorubicin, which tangles DNA to disrupt cellular replication, compromises a person's immune system.

Explore how cells respond to signals from their environment

In "Dropping Signals," users can drag stimuli, such as hormones and light, into various cellular environments to observe cellular responses. These include changing their shape, enabling the transport of chemicals into or out of the cell via the cell membrane, or dividing to compensate for surrounding damaged cells.

Modern genetic testing stems from a 1950s discovery about the cause of Down syndrome

Scientists found that an additional copy of chromosome 21 causes the disease and developed an approach to stain chromosomes so they could be manually sorted and counted, which is called karyotyping. The breakthrough discovery by Marthe Gautier, a young French doctor and cytogenetics researcher, was appropriated by a male colleague, who listed himself as the lead author of the study reporting the finding.

Organisms can possess multiple unique sets of DNA in one body

Genetic chimeras can result when cells with different DNA combine, such as when two sperm cells fertilize two egg cells, creating two embryos that then merge. In mosaicism, mutations arise within an organism after conception and can spread through cell division, resulting in diseases and forming genetically distinct anatomy.

Chemotherapy slows cancer by interfering with cell division

Cancer cells divide much more frequently than most normal cells. Most chemotherapy drugs are designed to interfere with cell division, thereby targeting harmful cells while attempting to leave healthy cells alone.

Fruit fly experiments helped identify genes responsible for major body development

The insects' fast life cycle and affordability have allowed geneticists to quickly identify which genes are responsible for limbs, eyes, and other body structures by inducing mutations. The same genes may be responsible for different parts of a species' body, such as limb-building genes being responsible for wing pigmentation in butterflies.

Cancer is typically described by one of five stages

Stage 0 is in situ, meaning abnormal cells haven’t spread, while Stage 1 is further progressed but remains localized to the origin. Stage 2 and 3 show increasing tumor size and spread to nearby lymph nodes or tissues. Stage 4 indicates metastasis, meaning cancer has spread to distant organs.

View a gallery of images and videos of over 200 types of cells

Funded by the National Institute of General Medical Sciences of the National Institutes of Health, the Cell Image Library houses over 60,000 pieces of media, including microscopic photographs, time-lapse videos of cellular activity, and 3D reconstructions of organic processes.

Exercise changes your genes without changing your DNA

Physical activity can turn beneficial genes on and harmful genes off, without altering the underlying DNA code. This engaging article explains the epigenetic mechanisms that take place with exercise and ultimately result in improved metabolism, lower inflammation, and optimized brain function.

Explore the efficiency of photosynthesis under various conditions

In this simulation, users can track how the cellular concentrations of ATP, NADPH, glucose, and oxygen vary over time in response to changes in temperature, acidity, carbon dioxide concentration, and the properties of incoming light. Through multiple trials, users can identify the optimal conditions for photosynthetic reactions.

Gene expression patterns are similar between ASD, schizophrenia, and bipolar disorder

Postmortem brain tissue analysis suggests there are genetic and epigenetic similarities between individuals with autism, schizophrenia and bipolar disorder. All three conditions appeared to have activation of genes in astrocytes and suppression of specific genes that function at the junction between neurons, called synapses. (Some users may encounter a paywall.)

Doctors use three key physical markers to determine biological aging

The length of the ends of chromosomes (known as "telomeres"), the gradual change in collections of DNA molecules called "methyl groups", and the secretion of inflammatory proteins are all used as indicators of biological age.

Visualize the difference between a healthy brain and one with Alzheimer's

The brain has three main parts—the cerebrum, brain stem, and cerebellum—each combining to control the entirety of the body's operations. Alzheimer's progressively deteriorates the circuitry in these structures, resulting in what we see as the symptoms of the disease.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

See how each of the more than two million known species relates to each other—and to common ancestors—in this zoomable tree of life.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

When you complete a CAPTCHA on a website to prove you are human, you may be unknowingly training algorithms for self-driving cars, whose systems require training data to help identify crosswalks, bicycles, and other outdoor objects.

Tattoos remain visible on your skin thanks to immune cells called macrophages

Explore chaos in this simulation of two double pendulums, where small differences in the release angles produce wildly different outcomes.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Explore the known asteroids, comets, and spacecraft involved in asteroid studies within our solar system with 'Eyes on Asteroids,' a 3D visualization from NASA.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

Browse a detailed visual analysis of over 200,000 similes—comparisons that often use 'like' or 'as'—from popular fiction to see how frequently writers the same idiomatic expressions.

Ebola is a filovirus, meaning it resembles a thread under a microscope, though it sometimes twists and can resemble a bowl of spaghetti.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Play the role of a student in a game where you try to navigate college and remain debt-free, selecting different income levels, high school experience, race, ethnicity, and more.

Artificial coral reefs have been 3D printed from nontoxic, biodegradable terracotta clay, which coral polyps have used as a foundation for rebuilding marine ecosystems.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

Learn how to read a prospectus, the juicy document that any company must file with the SEC before going public.

Search a massive database of over 4 decades of clues from the TV quiz show 'Jeopardy!'