Cancer is typically described by one of five stages

How does cancer spread through the body?

Cancer usually begins with one tumor, but it can spread to other organs if not removed. This video breaks down how cancer moves to these new areas and why some organs are more likely to get infected than others.

Metastasis: When cancer cells begin to travel through the body

Metastatic cancer starts in one part of the body and moves to another over time. This is known as metastasis. Such cancers are much more harmful since they attack multiple parts of the body, adapting new metabolic changes to suit the various environments found throughout a body.

Cancer is runaway growth of abnormal, mutated cells

Cancer cells have mutations in their DNA that allow uncontrolled growth and division, dodge usual mechanisms of cell death, and can often spread throughout the body. This is, in part, why the disease is so difficult to treat, with a wide variety of mechanisms and types that poses unique challenges.

Explore interactive global maps of cancer prevalence

Cancer is a ubiquitous disease, with populations across the globe having incidence rates that reflect various risk factors. The Cancer Atlas lets users explore a comprehensive global overview of cancer statistics, including incidence, mortality, prevalence, and survival rates across various regions and Human Development Index categories.

Timeline of cancer research milestones

While cancer remains incurable, there's been so much progress in its treatment over the last two decades. Nature provides an abridged history of milestones and major triumphs in cancer research and treatment. Start in the year 2000, and see how much has changed in the first quarter of the new millennium

There are hundreds of subtypes of cancer, making a universal cure nearly impossible

Cancer is an umbrella term for over 200 different diseases, each with its own subtypes, genetic mutations, and behaviors. This diversity means that a treatment effective for one cancer type or patient may be ineffective for others. Moreover, as tumors grow, their cells accumulate different mutations, creating subclones with unique characteristics.

How does cancer actually kill someone?

While the emotional and physical tolls of cancer are often clear, the innerworkings of how cancer kills can be confusing — and terrifying to discuss. Here, oncologists explain how cancer can progress.

The term 'cancer' is 3,000 years old

Around 400 BCE, Hippocrates is said to have named masses of cancerous cells "karkinos"—the Greek word for crab. Science and medical historian Dr. Howard Markel discusses a few hypotheses on why Hippocrates named the disease after a crab and how well cancer was understood in the ancient world.

Patients are a part of the progress

Navigating a cancer diagnosis can be terrifying and overwhelming. There is a robust community of patient advocates dedicated to prevention and diagnosis, research and clinical trials, legislation, needs of individual cancer types, among others. See how patient advocacy improves cancer research leading to improved treatment options and patient care.

US cancer mortality rates have been falling for 25 years

The American Cancer Society's "Cancer Facts & Figures 2025" report provides comprehensive statistics on cancer incidence, mortality, and survival rates in the United States. Cancer rates in the US continued a long-running downward trend, driven primarily by a steep drop in lung cancers (mostly from a decrease in habitual smoking) and better preventative monitoring. This site leads to incredibly in-depth reports and slides on the current state of the fight against cancer.

What is cancer bioengineering?

While new treatments for cancer are under continuous development, researchers are increasingly using engineering principles to find wholly new strategies to combat the disease. Directions include nanoparticle drug delivery, advanced imaging tools, developing new materials to interact with cells, tissue engineering, robotic surgeries, and more. Such interdisciplinary efforts are expected to unlock new tools and therapies beyond traditional drug formulation.

Roughly 1 in 5 cancers are caused by viruses

About 20% of cancers are caused by viruses, with seven specific oncoviruses causing between 10% and 15% of cancers worldwide. These include human papillomavirus and hepatitis B and C viruses, which can lead to diseases such as cervical and liver cancer. Understanding the mechanisms of these viruses is crucial for prevention and treatment strategies.

Large animals like giraffes and elephants have evolved unique cancer defenses

One may expect the larger an animal is, the more likely it is to develop cancer—simply because there are more cells and more chances for a dangerous mutation. However, some large animals show cancer rates almost 10 times lower than humans—a phenomenon known as Peto's Paradox.

Low cell division rates in heart cells make heart cancer particularly rare

The heart's location in the chest also offers protection from external cancer-causing factors. The disease affects about 3 in every 10,000 people, though most cases arise from metastasis from other body parts.

Immunotherapy focuses on boosting the immune system to fight cancer

The immune system detects and destroys abnormal cells, curbing the growth of many cancers. Immunotherapy works to boost the body’s immune system to target and kill cancer cells. There are many ways to accomplish this, including adaptive cell therapy, checkpoint inhibitors, vaccines, and monoclonal antibodies.

Prostate cancer is both manageable and the second-deadliest cancer for men

One in 44 men in the US will die from prostate cancer, while one in eight will be diagnosed with it. Commonly viewed as the safest cancer to have, screenings can save lives—but they can also cause complications for otherwise benign cases of the disease.

Explore the differences between healthy and cancerous cells using a DNA microarray

In this simulation, you will learn how scientists use microarrays to experiment on thousands of genes at the same time. By determining which genes are on or off, users can identify those that contribute to cancer formation.

Tumor genetic profiling can lead to targeted treatments

Genetic profiling of tumors—based on a sample from the tumor, a patient's blood, or both—can help clinicians determine if targeted therapies known to block the growth of certain types of tumors would be appropriate for specific patients.

Physician teaches course on being a cancer patient

Stanford physician and professor Bryant Lin was diagnosed with stage four lung cancer, a terminal diagnosis. Despite its difficult implications for his life, Lin embraced the chance to teach his students from the unique perspective of a lung cancer patient. The course explored the journey from diagnosis to treatment; how to respect a patient's physical, emotional, and spiritual dimensions; and more.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

How do 5G base stations work?

5G relies on a combination of base stations, including macrocells, small cells, and femtocells. The differences between the three are apparent in size, coverage, and cost—but, small cells in particular are key to providing the high millimeter wave frequencies 5G promises. Learn more in this three-minute video.

The five stages of grief—and what to do when yours doesn't follow this model

The "five stages of grief" is a well-established process used by many to move through periods of mourning. Grief is notoriously difficult to manage, and such procedures help move people forward. Only, what happens if your experience doesn't match the model at all? This podcast episode explores one researcher's unique approach to processing her own grief.

Postmenopause is a stage lasting roughly a third of a woman's life

Postmenopause is the final stage of menopause, occurring once a woman hasn't had any bleeding for a full year. She is then considered postmenopausal for the rest of her life. While some of the intense symptoms she might experience during perimenopausal will decline, her risk for certain conditions and diseases will increase.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Sclerosis is the technical term for the lesions or plaques that form without myelin

In the absence of myelin, the body forms scar tissue called sclerosis. That scar tissue hampers nerve's abilities to transmit nerve impulses, essentially acting as a roadblock to speedy communication.

Embryonic stem cells can develop into any other cell type in the body

Embryonic stem cells emerge around five days after fertilization, during the blastocyst stage of embryonic development. At this point, the embryo consists of about 100 to 150 cells and forms a hollow structure, and these cells are the ultimate source of all other cell types during fetal development.

Symptoms of extreme radiation exposure may take hours to manifest

Large doses of ionizing radiation can damage the body within minutes, particularly in the bone marrow and inner layer of the digestive tract. Victims may briefly seem fine before rapidly deteriorating as immune failure, infection and organ collapse set in.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Visualize the path of every solar eclipse from 1900 to 2099 and see what each looks like when observed from different locations on Earth.

Explore what it's like inside a patient isolation unit, used in situations such as treating a patient or suspected patient with Ebola.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

Corals are themselves not coral reefs—the term refers to the tiny marine invertebrates that build the rigid reef.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

An initial public offering or 'IPO' is the process of a private company becoming public by putting shares of the company on the stock market for purchase.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Most of the observable universe's volume consists of voids and supervoids—enormous regions of space with little to no galaxies, stars, or light.

Volcanoes 'die' when their supply of magma runs out, if they are shifted away from their underlying magma reservoir, or if they get clogged by collapsing or their magma cooling back into rock.

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

This poison ivy knowledge quiz—accompanied by photos of the plant's varied forms—may help you identify this common rash-inducing growth.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

The United States is one of only around two dozen countries with a fully federal system of government, in which power is divided between national and state governments.

Shooting stars, or meteors, are fragments of asteroids and comets that burn up as they enter Earth's atmosphere, creating streaks in the sky called meteor showers.

The first steps to rebuilding your credit score include getting to know exactly what's on your credit report and figuring out how far you are from the '700 club,' or 'good score' range.

Take a 3D tour of the Hajj, Islam's annual pilgrimage to Mecca, undertaken by over 1.5 million Muslims.

The Russia-Ukraine conflict is the largest ground war in Europe since World War II in casualties, forces mobilized, and displacement of civilians.