Prostate cancer is both manageable and the second-deadliest cancer for men

Breast, prostate, and lung cancer are the most common forms of the disease

Close to 1.8 million cases of cancer are diagnosed each year in the US, with more than 600,000 deaths (about 0.2% of the total population). This visualization tool offers a searchable database of aggregate statistics on common cancers by gender, race, state, and other demographic information.

About 40% of cancer cases are linked to preventable risk factors

Maintaining a healthy weight, engaging in regular physical activity, and consuming a balanced diet can lower cancer risk. Research indicates that about 40% of US cancer cases are linked to preventable factors, including poor diet and inactivity. Understanding these mechanisms empowers individuals to adopt healthier lifestyles for cancer prevention.

US cancer mortality rates have been falling for 25 years

The American Cancer Society's "Cancer Facts & Figures 2025" report provides comprehensive statistics on cancer incidence, mortality, and survival rates in the United States. Cancer rates in the US continued a long-running downward trend, driven primarily by a steep drop in lung cancers (mostly from a decrease in habitual smoking) and better preventative monitoring. This site leads to incredibly in-depth reports and slides on the current state of the fight against cancer.

America's top causes of death are heart disease, cancer, accidents, and stroke

Heart disease killed more than 680,000 people in 2023 and cancer killed around 613,000 people that year. Both causes of death are far above the next leading cause of death—accidents, which numbered around 223,000. Provisional data for 2024 indicates the leading causes of death remained the same.

Lung cancer advances are making a big difference

Lung cancer deaths are declining faster than new cases due to advances in treatment. The progress illustrates what is possible, even for a cancer that has long had a poor prognosis.

The HPV vaccine reduces cervical cancer rates by 90% or more

Cervical cancer is the fourth most common cancer in women globally. Almost all cases (99%) are linked to infection with high-risk human papillomaviruses. However, cervical cancer is both treatable and preventable—and we may be able to prevent most cases through vaccination.

MS disproportionately sickens women, but men tend to have worse outcomes

Though the disease is more common in women, men's symptoms progress more quickly, with men more often diagnosed with progressive MS and men's cases typically resulting in more severe symptoms—perhaps due at least partly to more delayed diagnosis—and more severe disability over time.

Cancer is typically described by one of five stages

Stage 0 is in situ, meaning abnormal cells haven’t spread, while Stage 1 is further progressed but remains localized to the origin. Stage 2 and 3 show increasing tumor size and spread to nearby lymph nodes or tissues. Stage 4 indicates metastasis, meaning cancer has spread to distant organs.

Large animals like giraffes and elephants have evolved unique cancer defenses

One may expect the larger an animal is, the more likely it is to develop cancer—simply because there are more cells and more chances for a dangerous mutation. However, some large animals show cancer rates almost 10 times lower than humans—a phenomenon known as Peto's Paradox.

One in 10 adults worldwide has diabetes

As of 2021, diabetes claimed at least 6.7 million lives and continues to kill one person every five seconds. Nearly one in two adults with diabetes don't know they have the condition, which is expected to increase in prevalence from 537 million in 2021, to 783 million in 2045.

Low cell division rates in heart cells make heart cancer particularly rare

The heart's location in the chest also offers protection from external cancer-causing factors. The disease affects about 3 in every 10,000 people, though most cases arise from metastasis from other body parts.

How does cancer actually kill someone?

While the emotional and physical tolls of cancer are often clear, the innerworkings of how cancer kills can be confusing — and terrifying to discuss. Here, oncologists explain how cancer can progress.

Two dogs were able to detect prostate cancer in 98% of patients in one study

In this small study published in 2015, two highly trained German Shepherd dogs sniffed hundreds of urine samples and were able to accurately detect prostate cancer—sniffing out certain volatile organic compounds—in almost every single case. One dog was correct 98% of the time and the other correctly identified patients 100% of the time. (Some users may encounter a paywall.)

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Learn why the Montreal Protocol may help prevent millions of cancer deaths

By restoring the ozone layer and reducing ultraviolet exposure, full implementation of the Montreal Protocol is expected to prevent about 443 million cases of skin cancer, 2.3 million skin cancer deaths, and 63 million cases of cataracts among Americans born from 1890 to 2100.

The number and quality of sperm in men's semen is down, giving rise to various movements to avoid 'spermpocalypse'

A typical fertile, healthy young man produces over 100 million spermatozoa, or sperm cells, in his testicles every day. Scientists agree sperm figures are generally moving in the wrong direction, but also emphasize there's still a lot to learn about sperm.

Cells become cancerous if checkpoints in the cell cycle are damaged

Before cells divide, a protein called p53 can halt the cell cycle if damaged DNA is identified, preventing the fault from propagating to daughter cells. If p53 and other tumor-suppressing molecules cannot function due to mutations or other instabilities, damage can accumulate over successive generations until nothing stops cells from dividing uncontrollably, creating tumors.

Stroke risk doubles each decade after age 55

While age is the greatest risk factor, genetics, diet, and overall health play a prominent role in determining individual stroke risk. Prevention focuses heavily on modifiable risk factors. High blood pressure is the single most important controllable risk factor, contributing to both types of stroke.

27% of US menopausal women used estrogen in 1999, but by 2020 that number was under 5%

The fallout of studies in the early 2000s linking hormone therapy for menopause and elevated cancer, stroke, and other health risks meant that even decades later—yet before the FDA removed its black box warning in 2025—use of HRT remained extremely uncommon. (Some users may experience a paywall.)

Drug-resistant staph infection is one of the deadliest superbugs

Methicillin-resistant Staphylococcus aureus (MRSA)—the superbug version of staph infection—is responsible for more deaths than any other superbug, killing more than 120,000 people globally each year. The bug is leading cause of hospital infections, and is harmless on the skin but causes severe symptoms once inside the body.

Autoimmune disorders are one of the top 10 killers of young and middle-aged women

Studies in the US and the UK, though conducted decades ago, have underscored that autoimmune diseases, when grouped together, are a top killer of women.

11 people died from firework injuries in the US in 2024.

As of 2026, the majority of US states have unsafe radon exposure levels

Alaska, South Dakota, Pennsylvania, Ohio, and Washington top the list of states with exposure levels above 4 picocuries per liter for this naturally occurring radioactive gas. While these state-level averages vary from one county, municipality, and home to another, the EPA encourages those in the highest-risk states to test their homes.

35% of polled Americans said they'd view people differently if they knew they had a mental illness

In April 2025 polling, mental health remained highly stigmatized in the US. Though 88% of US adults say a mental health disorder is nothing to be ashamed about, 84% of them think the term "mental illness" carries a stigma and only about half of respondents said they'd feel comfortable sharing their mental health struggles with others.

CTE is a major threat to NFL players

A week before Super Bowl LVII, Boston University released findings from a study diagnosing 91.7% of former NFL players in their 376-person study with chronic traumatic encephalopathy. It was a stark comparison to the less than 1% of CTE diagnosis in non-football players.

Astatine-211 is a radioisotope that can be used for therapeutic cancer treatment

With less than 30 grams in the Earth's crust at any given time, astatine is the rarest naturally occurring element. Its decay produces alpha particles that can damage diseased cells with the same impact as 10,000 electrons.

Jobs that marry each other the most

Out of all married physicians, roughly one in five is married to another physician. The trend extends beyond the medical field. Some professionals are more likely to marry one another than others. Find out which jobs most often pair together among married couples with this interactive tool based on estimates from the American Community Survey. Click here to type in your profession and see your most likely match.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

View the ten deadliest tornadoes in US history.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

About 12.5% of US adults experience a phobia in their lifetime, a diagnosis that hinges on the intense fear interfering with daily life and persisting for at least six months.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Watch the cumbersome, but necessary, precautions healthcare workers must take to care for and protect themselves while caring for Ebola patients.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

The US first hosted the World Cup in 1994, a tournament that lives in soccer infamy for its poor planning and the murder of Colombian player Andres Escobar, who'd accidentally scored on his own net.

Between 10 million and 50 million people in the US develop rashes from poison ivy, poison sumac, and poison oak each year.

44% of Americans say they pray at least once a day—discover how your state's religiosity stacks up against the rest of the country.

The US dollar is the most widely circulated currency in the world, and is involved in nearly 90% of global transactions

The identity of the Tank Man in the iconic photo from the 1989 Tiananmen Square protests remains unknown and was possibly killed.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

Learn how to read a prospectus, the juicy document that any company must file with the SEC before going public.

Neutron stars, the remains of some massive stars after they explode in a supernova, are the densest directly observable objects in the universe.

The Russia-Ukraine conflict is the largest ground war in Europe since World War II in terms of casualties, forces mobilized, and displacement of civilians.

In 2026, Finland was named the world's happiest country for the ninth consecutive year based on its wealth, social safety network, and high life expectancy, among other factors.

Despite being favored by 87% of Americans, Congress does not have term limits.

The distributor behind 'Rocky Horror' pulled the film from its scheduled national release, believing it would be a failure, though it eventually amassed a dedicated fanbase through midnight showings, a trend that continues over 50 years later.

Abraham Lincoln was almost assassinated weeks before his inauguration as he traveled from Illinois to DC through Baltimore in 1861; it took two independent claims for Lincoln to be convinced the threat was real