How does cancer actually kill someone?

How does cancer spread through the body?

Cancer usually begins with one tumor, but it can spread to other organs if not removed. This video breaks down how cancer moves to these new areas and why some organs are more likely to get infected than others.

Cancer is runaway growth of abnormal, mutated cells

Cancer cells have mutations in their DNA that allow uncontrolled growth and division, dodge usual mechanisms of cell death, and can often spread throughout the body. This is, in part, why the disease is so difficult to treat, with a wide variety of mechanisms and types that poses unique challenges.

When is someone actually dead?

Death is a process, not a sudden flip of a switch. Technology can now interrupt this process at various stages, begging the question of when exactly death happens in the dying process. This 33-minute podcast episode explores this question and the...

What is immunotherapy and how does it work?

Immunotherapy is a type of treatment that harnesses the body's immune system to combat cancer. This video explainer from the American Cancer Society discusses various types of immunotherapies and their roles in targeting cancer cells. Still a new and quickly evoliving field, immunotherapy represents a significant advancement in cancer treatment and offers new options for patients.

Chemotherapy slows cancer by interfering with cell division

Cancer cells divide much more frequently than most normal cells. Most chemotherapy drugs are designed to interfere with cell division, thereby targeting harmful cells while attempting to leave healthy cells alone.

Calculate your risk of developing cancer

Hosted by the National Cancer Institute, this tool provides interactive charts that display the likelihood of dying from various causes—including cancer—based on factors like age, sex, race, and smoking status. By contextualizing cancer risk among other potential health threats, users can create custom charts.

An Alzheimer's patient discusses her condition with children

Alzheimer's is a deadly disease that profoundly changes a person's abilities and personality, which makes it difficult to explain to kids. Responding to potentially uncomfortable questions with honesty (and relatable imagery) about the costs and nature of the disease goes a long way in fostering understanding.

Lung cancer advances are making a big difference

Lung cancer deaths are declining faster than new cases due to advances in treatment. The progress illustrates what is possible, even for a cancer that has long had a poor prognosis.

Using psychedelics to manage a cancer diagnosis

Dr. Roland Griffiths helped lead the revival of psychedelic research, often prescribing the use of psilocybin to address severe depression or anxiety in patients. This podcast explores how Griffiths leaned on his own career after being diagnosed with cancer and facing the prospect of death.

Infertility is often not discussed, forcing women and families to grieve privately

Watch this podcast discussion from Weill Cornell Medicine about the emotional journey of infertility for couples and individuals and hear advice about how to navigate the feelings of loss of control, grief, anger, and despair, including suggested tips for supporting individuals struggling with infertility.

America's top causes of death are heart disease, cancer, accidents, and stroke

Heart disease killed more than 680,000 people in 2023 and cancer killed around 613,000 people that year. Both causes of death are far above the next leading cause of death—accidents, which numbered around 223,000. Provisional data for 2024 indicates the leading causes of death remained the same.

The term 'cancer' is 3,000 years old

Around 400 BCE, Hippocrates is said to have named masses of cancerous cells "karkinos"—the Greek word for crab. Science and medical historian Dr. Howard Markel discusses a few hypotheses on why Hippocrates named the disease after a crab and how well cancer was understood in the ancient world.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Watch what the Ebola virus does inside our cells and organs in order to spread and survive.

How Nobel Prize-winning research unraveled why the immune system doesn't always attack itself

The 2025 Nobel Prize was awarded to scientists who discovered how immune system soldiers are typically stopped from attacking healthy tissue. The work furthered autoimmune understanding and cancer therapies.

The disease no one survives (yet)

Creutzfeldt-Jakob disease is currently incurable and can cause one's death within months of symptoms appearing. It involves misfolded proteins that, for some reason yet unknown to science, aren't cleared by the brain as typical and instead trigger similar proteins to misfold. These malformed major prion proteins—prion being a portmanteau of protein and infection—clump inside nerve cells, blocking signals crucial to processes ranging from speaking to organ function.

Cells cannot grow forever due to escalating inefficiency in transporting chemicals

As cells get larger, their volume grows much faster than the surface area through which nutrients and waste products pass, creating a bottleneck that eventually causes cells to die. This forces nearly all organisms visible to the naked eye to comprise enormous numbers of smaller cells, such as the approximately 30 trillion found in the average adult human.

Virtually experience a euthanasia roller coaster

In 2010, Lithuanian artist Julijonas Urbonas came up with a fictional euthanasia coaster to generate conversation about humanely ending life. His idea involved using extreme G-forces on a roller coaster, aiming to give participants feelings of euphoria before death. In reality, the ride would probably be extremely unpleasant.

How the feared self fuels OCD

Obsessive-compulsive disorder is characterized by intrusive thoughts that prompt people to enact compulsions—behaviors intended to relieve the anxiety or stress from the obsession. A significant intrusive thought OCD sufferers endure is the fear they will become a dangerous or immoral person. Therapeutic approaches try to show patients this is just a story that can be set aside.

What is asbestos, actually?

Asbestos can hurt you, but not many people understand how or why. Asbestos is actually a stone, once frequently employed as a construction material due to its strength, softness, fire-resistance, and biodegradability. However, when working on old homes or furniture, it may be released into the air, and extended exposure to its particles may cause lung cancer. Its use in new construction has been banned, but it remains a hazard. Learn more here.

See why food poisoning makes you feel nauseous

Scroll through these illustrations to learn what’s happening behind the scenes with bacterial foodborne illnesses, including why we sometimes vomit and how the body reacts to toxins secreted by bacteria.

What is the most painful thing in the world?

Pain is famously difficult to quantify, and though our response to it may be subjective, most pain does have underlying objective causes. So what's the most painful thing of all? Many say childbirth, or a broken femur, but this article lays out one case for why, of all things, kidney stones may be the most painful experience. Prepare yourself to find out here.

How do brain scans work?

There’s only one thing in our solar system sophisticated enough to study itself: the human brain. But this self-investigation is challenging because a living brain is shielded by skull, swaddled in tissue, and made up of billions of tiny cells. How do we study living brains without harming their owners? Two experts explain how the various techniques like EEGs, fMRIs, and PETs work in this TedEd talk.

Ebola has an average fatality rate above 50%

The Ebola virus is one of the planet’s most feared bugs. Symptoms begin with fever and fatigue but quickly develop into severe vomiting, diarrhea, and internal and external bleeding. But why is it so deadly? In short, Ebola hijacks the immune system to rapidly make replicas of itself.

Symptoms of extreme radiation exposure may take hours to manifest

Large doses of ionizing radiation can damage the body within minutes, particularly in the bone marrow and inner layer of the digestive tract. Victims may briefly seem fine before rapidly deteriorating as immune failure, infection and organ collapse set in.

What it feels like to crash an F1 car

Crashes are common in Formula 1, but due to improvements in safety measures like the HANS device and the Halo, driver deaths are far less common. But what does it feel like to crash? This video features the world's top drivers talking about specific crashes and their thought process as they head toward the wall at 150 mph.

Anticipatory grief describes experiencing sorrow ahead of a loss

All-consuming anticipatory grief—like if you know a loved one will soon die from a chronic illness—can be disabling. Seeking exercise, healthy food, hobbies, and trying to toggle between thinking about an upcoming loss and focusing on other matters is important for promoting health.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

The deadliest aspect of volcanic eruptions is often not lava, but pyroclastic flows—avalanches of ash, gas, and rock that can move more than half the speed of sound.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Tattoos remain visible on your skin thanks to immune cells called macrophages

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

According to the physics of black holes, our 4D reality may be a hologram—a projection of information coded on a 2D surface on the edge of the universe.

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

Georgia O'Keeffe's flower paintings are often assumed to be sexual, though the artist claimed she was simply interested in highlighting the beauty of flowers that most people neglect

The Dracula character, now seen as the vampire archetype, was inspired by a seafood-induced nightmare its creator experienced.

The price of gas is a composite made up of several different factors, with the federal gas tax making up less than 20% of what drivers pay at the pump.

Visualize the path of every solar eclipse from 1900 to 2099 and see what each looks like when observed from different locations on Earth.

Corals are themselves not coral reefs—the term refers to the tiny marine invertebrates that build the rigid reef.

US intelligence allegedly pursued more than 600 schemes to assassinate Cuban revolutionary Fidel Castro.

Existentialist writer Jean-Paul Sartre coined the famous phrase 'Hell is—other people' in his play 'No Exit'

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

An initial public offering or 'IPO' is the process of a private company becoming public by putting shares of the company on the stock market for purchase.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.