The term 'cancer' is 3,000 years old

Evidence of cancer has been found in a 1.7-million-year-old fossil

Cancer has existed as long as humans have, with some of the earliest evidence found among fossilized bone tumors, human mummies in ancient Egypt, and ancient manuscripts. The oldest example was uncovered in a toe—millions of years old—from an ancestor of modern-day humans.

'Melancholia' was the ancient Greek term for depression

"Melancholia" in Hippocrates's time was derived from the Greek word for black bile. This term made sense in its context since the Greeks believed that depression stemmed from an improper balance of the four humors.

Cancer is typically described by one of five stages

Stage 0 is in situ, meaning abnormal cells haven’t spread, while Stage 1 is further progressed but remains localized to the origin. Stage 2 and 3 show increasing tumor size and spread to nearby lymph nodes or tissues. Stage 4 indicates metastasis, meaning cancer has spread to distant organs.

Timeline of cancer research milestones

While cancer remains incurable, there's been so much progress in its treatment over the last two decades. Nature provides an abridged history of milestones and major triumphs in cancer research and treatment. Start in the year 2000, and see how much has changed in the first quarter of the new millennium

There are hundreds of subtypes of cancer, making a universal cure nearly impossible

Cancer is an umbrella term for over 200 different diseases, each with its own subtypes, genetic mutations, and behaviors. This diversity means that a treatment effective for one cancer type or patient may be ineffective for others. Moreover, as tumors grow, their cells accumulate different mutations, creating subclones with unique characteristics.

Cell theory originated from microscopic observations of cork and dental plaque

In the mid-1600s, Robert Hooke identified compartment-like structures—which he called cells—in cork, and Anton van Leeuwenhoek discovered bacteria in samples of his dental scrapings. Almost 200 years later, Matthias Schleiden and Theodor Schwann showed that plants and animals, respectively, are composed of cells, proving that cells are the foundation of all living things.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Food allergies were first documented more than 4,000 years ago

Although food allergies are on the rise in modern times, they have been documented in written records for thousands of years. More than 3,000 years ago, Chinese emperors advised patients to avoid certain foods, and Hippocrates noted in his work that food could cause serious harm to certain individuals, and even lead to death.

Why don't we all have cancer?

The creation of a single cell produces 120,000 genetic mutations that can lead to cancer. This video investigates how our bodies proofread and autocorrect those mistakes.

Analysis finds dementia was rare in ancient Greece

Ancient medical texts seldom mention severe cognitive decline, suggesting that such conditions were uncommon. This scarcity is attributed to factors like shorter lifespans and active lifestyles, implying that modern environmental and lifestyle changes—along with longer life expectancy—contribute to the current prevalence of dementia.

How race science influences breast cancer research

Despite researchers' and physicians' pushback, race is still used in studies and clinics to categorize human differences in health conditions and treatment responses. This article explores how race has influenced breast cancer research. Considering race as a factor in cancer research, diagnosis, and treatment can lead to racial inequalities. Sociocultural factors, including food access and air pollution, greatly influence health outcomes.

The economics of horseshoe crab blood

Horseshoe crabs are older than dinosaurs and have survived five mass extinctions that wiped most life from the planet. But it's only now that their future as a species is in danger. This blood, worth about $60,000 per gallon, is hyper-sensitized to certain bacteria that are fatal to humans. This 17-minute podcast dives into humanity's pursuit of horseshoe crab blood, a "somewhat magical" mixture heavily relied on by the pharmaceutical industry.

Medical recognition of strokes stretches back to ancient Greece

Every minute, 750 milliliters of blood flows to the brain, supplying 20% of the body’s oxygen. A sudden disruption—whether from a clot (ischemic stroke) or a bleed (hemorrhagic stroke)—can be life-threatening. From ancient Greek theories to modern CT and MRI scans, here’s how stroke science has evolved over time.

Meet Hipparchus, the Greek astronomer who created the world's first star map

Astronomer Hipparchus created accurate maps of the night sky way ahead of his time, with coordinates sometimes within a single degree of modern values. Hipparchus founded a new theory of star motion, modeling the sky as a celestial sphere with coordinates similar to latitude and longitude—concepts only recently created in Hipparchus' time.

The medical profession has a dark history of 'body snatching' for education

This term originally referred to secretly removing corpses from graves for sale—usually to medical schools where they were used for education. The practice dates back at least to the 1300s but still—much more rarely—persists today.

The origin of cyborgs

The term "cyborg" was coined in a 1960 academic paper discussing what alterations humans would need to undergo to survive in extraterrestrial environments, a venture far "more logical than providing an earthly environment" in space. According to authors Manfred E. Clynes and Nathan S. Kline, Cyborgs with a capital C have incorporated exogenous components that extend their ability to adapt to new environments. Read the paper here.

Robert Koch won the Nobel for his tuberculosis work, but he also pioneered cholera research

Koch was one of the first scientists to isolate the bacterium that causes cholera while investigating an outbreak in Egypt in 1883. He went on to advise about rules to control cholera outbreaks, which formed the basis of the disease control approaches and water hygiene techniques still used today.

The marathon’s roots can be traced back to a Greek myth

Legend has it that the first marathon took place in 490 BCE, when Pheidippides, an ancient Greek soldier, ran from the Battle of Marathon back to Athens—approximately 25 miles—to inform his people they’d defeated the Persians. The story is likely apocryphal: No Greek historian mentioned it until over 500 years later.

Computer viruses' hijacking abilities led them to be named after biological viruses

Just as their counterparts infect cells and take control of cellular processes to replicate endlessly, computer viruses cannot replicate on their own and must copy their code into host software before duplicating when the program or file is opened. The term "virus" comes from the Latin word for "venom."

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

The mystery of the cucumber, from coiling tendrils to its bitter, mature fruit

Cucumus sativus was first cultivated 3,000 years ago in the Himalaya of India, appearing in ancient Sanskrit hymns in the Hindu tradition. They are typically harvested well before maturation, as their yellow, final fruit is bitter. Their coiling tendrils were so distinct they prompted famed naturalist Charles Darwin to publish one of his lesser-known works, "On the Movements and Habits of Climbing Plants." Its refreshing coolness inspired cucumber-derived body washes and sprays over millennia.

Cacao is a Maya word that survives today

In the 1980s, archaeologists finally deciphered Maya hieroglyphs in part by identifying known words. Maya scholar David Stuart notes that cacao—still used today—was one of the key linguistic anchors that unlocked ancient Maya texts.

'Dracula' was inspired by a seafood-induced nightmare

Bram Stoker, the author of the classic horror novel, said that a dinner of "dressed crab" led to unsettling dreams about "a vampire king rising from the tomb." He'd revisit that vision, eventually creating the iconic titular vampire.

Bake bread like a Roman, and honor Ceres, the goddess of wheat

Grains made up about 70% of the Roman diet, and the word "cereal" stems from the goddess Ceres—the Roman equivalent of Greece's Demeter—to whom they prayed for good harvests. Cato the Elder, a famous statesman, left behind a simple home recipe for a Roman loaf.

How muscles get their names

There are more than 600 muscles that crisscross the human body, and each has a name that's more than a simple label. Muscle names also typically communicate the muscle's size, behavior, length, location, appearance, direction, and attachments to bone. These names usually have Greek or Latin roots, such as in the case of the deltoid muscles, which are named in reference to the Greek letter delta (𐤃).

Ancient civilizations predicted eclipses by tracking different cycles of their recurrence

The periodic nature of the orbits of the sun, moon, and Earth results in several series called saros cycles, in which the geometric configuration of these celestial bodies that produces an eclipse recurs after about 6585 days. Because eclipses are viewable from different locations on Earth, there exist many saros cycles, one for each ecliptic configuration.

The word 'hoax' comes from the phrase 'hocus-pocus'

The famous phrase "hocus-pocus" combines liturgical Latin and gibberish. It's a silly series of words often said during magic tricks. The phrase naturally evolved into "hoax" over time and became a standard English word around the year 1800.

The term 'algorithm' originated from the Latinized name of al-Khwārizmī, a 9th-century mathematician whose works introduced Arabic numerals and the decimal-based numeral system to Europe and whose treatise 'Al-Jabr' gave algebra its name.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

The Dracula character, now seen as the vampire archetype, was inspired by a seafood-induced nightmare its creator experienced.

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

Graffiti dates back to at least ancient Pompeii, where citizens scrawled messages to one another on public walls

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

Corals are themselves not coral reefs—the term refers to the tiny marine invertebrates that build the rigid reef.

During the French Revolution, a botanist's letter asking about "dear Rhus" (poison ivy) was intercepted, leading authorities to suspect he was conspiring with the Russians.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

This real-time tracking of the hantavirus cruise ship outbreak in May 2026 offers a unique glimpse into the global reach of the outbreak and whether the virus sickened passengers and their communities around the world.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

The word 'jazz' evolved from 'jasm,' 19th-century American slang for 'energy'

Visualize the path of every solar eclipse from 1900 to 2099 and see what each looks like when observed from different locations on Earth.

SpongeBob exemplifies Aristotle's philosophy for living well because he understands that happiness doesn't come from external factors like money, recognition, or power.

Ebola is a filovirus, meaning it resembles a thread under a microscope, though it sometimes twists and can resemble a bowl of spaghetti.

In 2019, a laptop loaded with six of the worst malware in history and described as 'an exhibit of historical weaponry' sold for $1.3M.

Sears sold DIY house kits starting at $600 in its famous catalog from 1908 through the 1940s, resulting in roughly 10,000 'Sears and Roebuck houses' being built.