'Melancholia' was the ancient Greek term for depression

Hippocratic doctors treated severe mental illness with the poisonous plant hellebore

Since symptoms like hallucinations were believed be due to an imbalance of black bile, yellow bile, blood, and phlegm, the treatment at the time was to bring those humors back into balance. That meant standard treatments could include bleeding a patient or using substances like hellebore to induce vomiting or diarrhea.

The term 'cancer' is 3,000 years old

Around 400 BCE, Hippocrates is said to have named masses of cancerous cells "karkinos"—the Greek word for crab. Science and medical historian Dr. Howard Markel discusses a few hypotheses on why Hippocrates named the disease after a crab and how well cancer was understood in the ancient world.

Anhedonia, which means 'without pleasure' in Greek, is typical in major depressive disorder

This common symptom—a flat affect—results in previously enjoyable hobbies no longer bringing pleasure. People with anhedonia may also avoid social situations because they anticipate they'll bring no joy, not because of anxiety or fear.

Hear what ancient Greek music sounded like

Greek poetry was usually created with the intention that the words would be sung along with music. Evidence and reconstructions of ancient melodies and instruments mean researchers and musicians of today can play music in which the final notes have long since faded.

Having five of nine key symptoms constitutes a major depression

Before professional standards were adopted, practitioners used varying criteria to diagnose mental health disorders. By the 1970s, more objective lists were organized, culminating in this list of polythetic criteria—a list of symptoms where no single criterion is required, but a minimum number must be present.

Analysis finds dementia was rare in ancient Greece

Ancient medical texts seldom mention severe cognitive decline, suggesting that such conditions were uncommon. This scarcity is attributed to factors like shorter lifespans and active lifestyles, implying that modern environmental and lifestyle changes—along with longer life expectancy—contribute to the current prevalence of dementia.

See how antidepressants were discovered

The decadeslong journey to the three major types of antidepressants began with medications designed to treat other maladies. Watch to learn more about how attempts to treat tuberculosis and blood pressure disorders led to new insights about neural chemistry and mood.

'Mental hygiene' was the 1843 term for mental health

It was coined by American psychiatrist William Sweetzer to reference the same idea as personal hygiene. Mental hygiene, in Sweetzer's view, needed to be maintained in the same way people attend to their personal cleanliness, an idea that was supplanted by better understanding of the complexities of mental health disorder causes in the decades that followed.

Cholera was called the 'Blue Death'

In the mid-1800s—when John Snow identified cholera in London—the disease was known simply as the "Blue Death." That's because blood would thicken in patients' veins when they were struggling with extreme dehydration. As a result, their skin would turn a blueish hue as their blood was starved of oxygen.

Poliomyelitis is derived from Greek

Polio, formally called poliomyelitis, comes from the Greek words for gray (polios) and marrow (myelos)—a reference to the spinal cord tissue that, when infected by the virus, causes paralysis.

When Marcus Aurelius created endowed philosophy chairs in Athens

The Roman Emperor Marcus Aurelius is known as one of the most famous Stoic writers or thinkers, penning his classic opus ‘Meditations.’ In 176 CE, he endowed four philosophy chairs in Athens: one for Stoicism, and one for three of Stoicism’s rival schools: Aristotelianism, Platonism, and Epicureanism.

The word 'vertigo' derives from the Latin 'vertere,' meaning to turn

Beyond the word's origin, this article makes clear that fuzzy definitions of the disorder make it confusing for patients to describe it.

Malaria comes from the Italian term 'mal'aria,' meaning 'bad air'

The term refers to marshy areas associated with the disease. An estimated 94% of malaria cases—215 million—occur in Africa.

SAD disrupts melatonin secretion, producing it longer in the morning

The hormone is secreted from the pineal gland in the brain and is key to the timing of sleep. However, the substance does not generate sleep itself. With seasonal affective disorder, the body misperceives the photoperiod—the time with light—and the cycle of sleeping and waking gets off-phase, leading to issues with circadian rhythms.

Scholars trace existential anxiety back to early Hebrew scriptures

Paul Megna, a scholar of literature and philosophy, notes that the existentialist ideas of Kierkegaard (and, to a lesser extent, Sarte and Camus) had their roots in much earlier texts, which posited that "fear of the Lord" was "the beginning of wisdom."

The term “Middle Ages” was invented by Renaissance thinkers to belittle the era

The label “Middle Ages” reflects Renaissance writers’ admiration for ancient Greece and Rome, not medieval reality. They frame the post-Roman centuries as a cultural backslide—a view later reinforced by Edward Gibbon and modernized as the “Dark Ages” myth.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Ménière's disease was first identified in 1861

This condition is named after the French clinician Prosper Ménière, who first identified it as being linked to the inner ear, noting it was a disorder of the semicircular canals. It tends to occur in people who are 40 years old or older.

The scientific name for northern lights came from two Greco-Roman gods

Although cave paintings may have depicted them millennia earlier, one of the oldest known references to auroras is a Babylonian cuneiform tablet from about 600 BCE. In 1619, Galileo Galilei named the phenomenon in the northern hemisphere "aurora borealis" after the Roman goddess of dawn—Aurora—and the Greek god of the north wind—Boreas.

For the medievals, the moon was a versatile religious symbol

Within the distinct traditions of Christianity and Islam, the moon became a central metaphor and sign for religious teaching. For Christians, its light was used to explain Jesus' humanity with the light of the sun (divinity). For Muslims, the moon represented a cosmic longing for god.

There are three main types of satire: Horatian, Juvenalian, and Menippean

These classifications are based on the Roman poets who popularized them. Horatian is good-natured and lighthearted, Juvenalian is bitter and more caustic, and Menippean contains many layers.

The word peptide comes from Greek

Originating from the Greek term "peptos," which means digestible, peptide as a word refers to two or more amino acids. (Some users may encounter a paywall.)

Picasso's Blue Period was inspired by loss

Picasso's friend Casagemas, a poet he met in Barcelona, died by suicide in 1901. The event shook the young Picasso, leading to what would later be called his Blue Period. The work from this time reflected the loss of Casagemas and others, as well as broader themes of suffering and marginalization in society, portraying their faces and other outcasts of society in elegiac hues of blue and other cold colors. The era is one of the artist’s most famous bodies of work, including several iconic paintings, such as "The Death of Casagemas," pictured below.

Adaptations of Hamlet's most famous soliloquy often change its meaning

The directors of the many "Hamlet" film adaptations have used setting, context, and tone to reframe the "To be, or not to be" monologue. Laurence Olivier's 1948 version presents it as a meditation on suicide; Kenneth Branagh's 1996 version interrogates surveillance. Lucy Zhao's 2025 film "Hamnet," although not a true adaptation of the play, utilizes the soliloquy twice to illustrate how characters grapple with grief.

How did the bull and bear markets get their names?

The terms "bull" and "bear" are used to describe certain sentiments or activities in the financial markets. A bear market refers to declining stock prices and pessimistic outlooks, whereas a bull market represents the opposite.

The word 'dystopia' was first used in 1868

John Stuart Mill, an English philosopher, economist, and politician, uttered the word at the House of Commons while criticizing what he considered to be the government’s insufficient land policy for the Irish, saying, “What is commonly called Utopian is something too good to be practicable; but what they appear to favour is too bad to be practicable.”

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

For centuries, it was common to sleep in two shifts: a few hours at the beginning of the night, and a longer period beginning around midnight

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

The first horror movie is believed to be George Méliès' 1986 short 'The Haunted Castle,' which pioneered the use of special effects

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

See photos of Meteora, a mountainous site in central Greece, home to 14th-century monasteries perched atop soaring outcroppings.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

The word 'jazz' evolved from 'jasm,' 19th-century American slang for 'energy'

While the sun's gravity keeps the planets in orbit, their gravity also pulls on the sun, causing it and everything else in the solar system to orbit around a mutual balance point called the barycenter—the true center of the solar system.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

Visualize the path of every solar eclipse from 1900 to 2099 and see what each looks like when observed from different locations on Earth.

SpongeBob exemplifies Aristotle's philosophy for living well because he understands that happiness doesn't come from external factors like money, recognition, or power.

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Mid-century modern graphic designers, known for their bright colors and bold lines in advertising, also found success with children's books.

Apollo astronauts left items in the moon's 'toss zone,' including golf balls, family photos, and bags of human waste, to make room for lunar rocks.

El Niño, Spanish for 'the boy,' was named after Jesus Christ because the phenomenon resembled the weather changes observed around Christmastime.

Poison ivy's characteristic rash is caused by an allergic response to an oily compound in the plant called urushiol.

Famed poet TS Eliot rejected the manuscript for George Orwell's political fable 'Animal Farm,' writing that its criticism of authoritarianism was not 'the right point of view.'

Use this calculator to find the dollar value of your mental load, from meal planning to coordinating after-school care for your children.

In 2026, Finland was named the world's happiest country for the ninth consecutive year based on its wealth, social safety network, and high life expectancy, among other factors.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.