Food allergies were first documented more than 4,000 years ago

Adults are developing food allergies that they didn’t have as children

Research published in 2019 found that almost half of 40,000 surveyed adults with food allergies developed a new food allergy as adults, underscoring that our immune systems may newly misclassify substances later in life.

Human records of influenza stretch back more than two millennia

Accounts of flu-like illness appear as early as 412 BCE, when Hippocrates described a sudden wave of cough and fever. Centuries of recurring outbreaks culminated in the first clearly documented pandemic in 1580, spreading from Asia into Europe and Africa.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Alexander the Great, Rudyard Kipling, and more may have died from food poisoning

Though it is hard to prove decades or centuries after their deaths, some researchers suspect that food poisoning killed a variety of historical figures, including US President Zachary Taylor in 1850: Some researchers believe he may have consumed food contaminated with *Salmonella*.

Ice cream can be traced back to the 7th century

Documents from ancient China refer to a frozen milk dish, a predecessor of the treat we now know. That evolved into a blend of buffalo milk, flour, and fragrant camphor oil that more closely resembled our ice cream.

Evidence of opium use dates to as early as 5000 BCE

Archaeological evidence shows the use of the poppy plant for its pain-killing properties likely originated in the Mediterranean before making its way to the East and West via trade. It has since inspired two eponymous wars, and highly addictive derivatives of the naturally occurring substance have led to an ongoing overdose crisis.

Learn the history of food science breakthroughs from the 20th century

Long after humans developed the means to produce sufficient food to feed civilizations, scientific research focused on a wide variety of objectives, such as developing methods to preserve food quality (accomplished via frozen food), speeding up cooking (leading to the microwave), and lowering the cost of sweetening food, which high fructose corn syrup provides.

Even in recent history, adaptations to the environment drove human evolution

Through genetics, environmental pressures, and cultural influences, humans have evolved to tolerate lactose, develop varying skin pigmentation, and acquire genetic resistance to diseases like bubonic plague. The metabolic and digestive systems of Indigenous peoples have adapted to their diet, which is influenced by the availability of food and water.

Human beekeeping has been traced back to 7000 BCE

Eighty-seven of the world's leading crops rely on pollination in some way, including 43 that are highly dependent or entirely reliant on it. Without pollinators, key foods such as apples, avocados, and almonds would likely become extinct, pushing entire ecosystems into collapse.

Anorexia as religion: from the Middle Ages to modern message boards

Humanity's interest in anorexia nervosa can be traced back to the Middle Ages and the rise of "fasting girls." This article explores the history of the eating disorder as a religion. The first recorded anorexics appeared during the 13th century...

East Asian records of auroras may date back to 10,000 BCE

Ancient texts from Japan, Babylon, and China contain accounts of auroras dating back millennia. Because auroral activity and intensity are driven by periodic ebbs and flows in solar activity, these records allow scientists to identify patterns that may help anticipate particularly dangerous future solar storms.

The term 'cancer' is 3,000 years old

Around 400 BCE, Hippocrates is said to have named masses of cancerous cells "karkinos"—the Greek word for crab. Science and medical historian Dr. Howard Markel discusses a few hypotheses on why Hippocrates named the disease after a crab and how well cancer was understood in the ancient world.

Why pickles became a thing

Pickles began in Mesopotamia around 2400 BCE as a way to preserve vegetables amid heat (and spoilage). They spread through Egypt, Greece, and Rome, where Julius Caesar reportedly fed pickles to his soldiers, and brining was treated as a culinary art. The technique is broadly useful, as salt and water can extend the shelf life and deepen flavor for almost anything.

Natural food stores began sprouting up in the US in the 1960s and 1970s

Health food stores began opening in the ‘50s, though they were primarily focused on vitamins and holistic supplements. Natural food stores, however, provided pesticide-free produce and often relied on local farmers for their products. One of the first was New Age Natural Foods, in San Francisco’s Haight-Ashbury neighborhood, which opened in 1965.

How fecal transplants work

1,700 years ago, Chinese alchemist Ge Hong was renowned for his soup that could cure diarrhea-stricken patients. It had a surprising secret ingredient: feces. While it might seem unwise to consume feces, exciting new research suggests that taking...

Analysis finds dementia was rare in ancient Greece

Ancient medical texts seldom mention severe cognitive decline, suggesting that such conditions were uncommon. This scarcity is attributed to factors like shorter lifespans and active lifestyles, implying that modern environmental and lifestyle changes—along with longer life expectancy—contribute to the current prevalence of dementia.

Cats began cozying up to humans around 10,000 years ago

The feline family is a hugely diverse group of lions, panthers, and kitties that have spread all over the world. The ancestors of the cats we love today helped solve rodent problems when humans first invented agriculture. They've been worshipped, loved, and scorned by humans since.

Learn more about the history of fireworks, which dates back to an accidental invention during an alchemist's quest for information about immortality.

The term 'alcohol' has Arabic origins

Linguistic research reveals a lot about the ancient origins of alcohol. For example, studying various languages reveals that "mead," an alcoholic beverage made from honey, came even before wine.

Cookies were originally used as low-stakes ways to test the temperature of an oven

In 7th century Persia, bakers used small mounds of dough to test the heat in ovens before baking larger cakes. Afterward, they'd add honey, nuts, and other items to the small mounds, creating early cookies.

Yoga dates back to about 1500 BCE

The earliest known mention of the word is in the Rig Veda, one of the four canonical Hindu texts. Rishis, or sages, then documented its evolution in the Upanishads, the Hindu scriptures. Much of the modern understanding of Yoga comes from “Yoga Sutras of Patañjali,” which outlines the practice’s eight elements, including physical postures and breathwork.

Learn more about the history of fireworks, which date back to an accidental invention during an alchemist's quest for information about immortality

When bamboo in China was tossed into fire in 200 BCE, there was an explosion. About 1000 years later, around 800 CE, an alchemist searching for secrets to immortality mixed sulfur, charcoal, and potassium nitrate together, leading to gunpowder. That mixture was then packed into bamboo or paper tubes, leading to fireworks.

Rome's herbal panacea may not be as extinct as we thought

Silphion: cure-all, aphrodisiac, birth control, tasty seasoning. Nero allegedly ate the last of this miracle plant. This article details how a researcher may have found more. Seven centuries after the yellow-flowered plant was first documented growing in what's now Libya, it vanished. Historians proposed that the loss of Silphion may have been the first recorded extinction of any species.

Monosodium glutamate is a sodium salt form of a naturally occurring amino acid

Monosodium glutamate myths originate from a 1968 letter to the New England Journal of Medicine, in which unpleasant symptoms after eating Chinese food were dubbed Chinese restaurant syndrome without medical data. Subsequent studies show this savory flavor enhancer—found in tomatoes, mushrooms, and other foods—is safe in moderation.

Poison ivy's characteristic rash is caused by an allergic response to an oily compound in the plant called urushiol

Chinese lacquer tree sap also contains urushiol, yet the sap was widely used as a lacquer in Asian lacquerware for thousands of years. The word "urushiol" is derived from the Japanese word "usushi," which is the word for the lacquer tree.

Visualize the 5,000-year history of consumer credit in one infographic

Consumer loans for agriculture were likely first used around 3500 BCE, but modern consumer credit took many more centuries to be established. England's credit reporting system, for instance, dates back to the early 1800s when a group of English tailors began swapping information about customers who failed to settle their debts.

Ancient Egyptians developed the first pregnancy test—and scientists tested it in the 1960s

A papyrus from about 1350 B.C.E. discusses a test in which a woman would urinate on wheat and barley seeds over the course of several days. If the barley grows, she's having a male child; if the wheat grows, it's a female child; and if nothing grows, she's not pregnant. Scientists went on to test this theory in 1963 and found that about 70% of the time, the urine of pregnant women did promote growth whereas the urine of nonpregnant women didn't—perhaps due to estrogen levels in the urine.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Urushiol, the oily toxin in poison ivy, can remain allergenic on clothing for years.

Graffiti dates back to at least ancient Pompeii, where citizens scrawled messages to one another on public walls

Animal phobias are likely the most common type of phobias, followed by an extreme fear of heights.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

The history of many kitchen appliances involves unexpected discoveries and applications, including wartime radar turned hamster defroster and replacing an 'ice king' with heat-stealing boxes.

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

20,000 letters to the advice columnist 'Dear Abby' provide insight into prevailing sex, religion, and LGBTQ fears, anxieties, and concerns from the 1950s onward.

Double world record holder Hunter Ewen helped conquer his fear of balloons, called globophobia, by training to win Guinness World Record titles for balloon inflation.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

Many legends about George Washington, including his supposed wooden teeth and the story of cutting down the cherry tree, lack evidence.

English mathematician Ada Lovelace wrote the first computer algorithm a century before computers existed and hypothesized that computing devices would one day be able to compose music—foreseeing the generative AI systems of today.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

While the first exchange-traded fund (a 'basket' of different assets that can be bought and sold on a stock exchange) in the US only launched in 1993, the global ETF market has grown to more than $10T in the short time since.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

The US Constitution is widely regarded as the longest-standing written national constitution still in force—see how it has influenced rights worldwide.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

NBA superstar Victor Wembanyama spent the 2025 summer training with monks in central China to enhance his body and mind.