Ancient Egyptians developed the first pregnancy test—and scientists tested it in the 1960s

Read the 1963 study testing out an ancient Egyptian pregnancy urine test

The study sought to test out the ancient Egyptian approach of having a woman urinate on barley and wheat seeds to ascertain pregnancy status. Surprisingly, the research concluded that pregnant women's urine did promote growth of cereal grains the majority of the time; nonpregnant women's urine did not. Unfortunately, the sex of the child could not be accurately predicted based on which crop grew.

Modern pregnancy tests detect a specific hormone in a woman's urine or blood

They pick up human chorionic gonadotropin, in either blood or urine. The hormone is produced by a woman's reproductive tissues during pregnancy.

The first prenatal screen for disease was developed in 1961

Scientist Robert Guthrie created a method to test newborns for a metabolic defect called phenylketonuria, or PKU. This blood test didn't look for gene variants—it hunted for excess phenylalanine in the blood. The disorder is caused by an inability to digest the amino acid phenylalanine, leading to excess phenylalanine in the body. PKU results in intellectual disability, seizures, and other symptoms if it isn't caught early and treated with a specialized diet.

Scientists first observed a sperm and an egg uniting in 1876

Throughout human history, scholars and researchers have speculated on the origin of human reproduction. It wasn't until the late-19th century that the physical process of egg fertilization via sperm cells was observed (in sea urchins), forming the basis for modern fertility research.

The first successful IVF pregnancy was in the United Kingdom in 1978

Gynecologist Patrick Steptoe and his collaborator Robert Edwards, a biologist, attempted to fertilize a human egg cell in a petri dish 101 times before finally succeeding. This resulted in the birth of Louise Brown—at the time referred to as a "test tube" baby—in 1978, who was born into the spotlight.

Ancient Egyptian papyrus from 16th century BCE seems to reference tinnitus

Ancient Egyptians wrote that they treated "bewitched ear" with herbal concoctions that involved frankincense and other ingredients, which were placed in the ear.

Tour the ancient world via beer

What did the people of yesterday make of beer, and how exactly did they make it? Explore the timeless beverage in this guide to ancient beers from around the world. Archaeological evidence suggests the rise of beer brewing may have coincided with humanity's shift from hunters to farmers. According to this article, beer was first enjoyed in ancient Mesopotamia, where paintings, poems, and myths glorified the porridge-like brew.

The pregnancy test industry is worth roughly $769M

The inventor of the at-home pregnancy test, Margaret Crane, largely hasn't taken credit for her invention until recently.

Ancient Egyptians played Senet, a board game where players threw sticks or bones as dice.

Due date is calculated from the first day of the last menstrual period—not when sex occurred

The standard counting system considers a woman pregnant from the first day of her last menstrual period, which means someone may technically—for the purposes of measurement—have become pregnant even before she had sex. This standard starting point is used because it reliably marks when the body began preparing for pregnancy—even though it's typically two weeks before conception. On average, most women are pregnant for 280 days from the last menstrual period.

The ancient Egyptians built prototypes of the modern Suez Canal

The idea to facilitate trade between the Mediterranean Sea and the Red Sea and connect the Eurasian continent was apparent even to pharaohs in the second millennium BCE. Though no physical traces remain, contemporary accounts attest to early, shorter versions of the canal, including from Herodotus.

Wealthy Egyptians slept on woven beds to allow air circulation in hot climates

The history of beds is a fascinating look at economics, social science, and cultural beliefs around what takes place during sleep. This brief survey of the history of bed-making begins roughly 5,000 years ago and runs through ancient Egypt and Rome to modern Europe. Take a look here.

The Ishango bone suggests mathematics was born about 20,000 years ago

Ancient civilizations developed mathematical systems for various purposes, including the Egyptians for the construction of the pyramids and the Ancient Greeks for logical reasoning in theorems. However, these systems were predated by the Ishango bone—found in the Democratic Republic of the Congo—whose notches suggest a base ten system, prime numbers, and simple mathematical operations.

Child mortality rates since ancient Rome

One of the great achievements of modern humanity has been the sea change in child mortality rates—the chance that a newborn eventually lives past puberty. For thousands of years, children had a 50% chance of not entering adulthood. About 300 years...

The earliest record of dream interpretation dates to Ancient Sumer

Ancient Babylonia was a hub for oracular studies. Dreams were seen as nightly dispatches from lower-world or chthonic deities, and practices including astrology, omen reading, and liver divination attained wide-reaching influence. Few surviving records of oneiromancy—interpreting dreams as revelations of future events—have been found.

Nail art can be traced back to 5,000 BCE

Archaeologists discovered Egyptian mummies with nail art and henna-tinted fingertips. The trend would continue informally for centuries until Revlon introduced modern nail polish in 1932.

A particle accelerator allowed researchers to noninvasively examine a mummy

The mummy hailed from the Faiyum oasis, where Egyptian and Roman cultures intersected, and was analyzed using the Advanced Photon Source at Argonne National Laboratory. The device used high-energy X-rays to probe the material composition of numerous objects embedded deep inside the mummy without damaging its remains.

The ultrarare 'Er' blood type has been documented only about 40 times

In 2022, the tragic loss of a pregnancy led researchers to the discovery that the rare "Er" blood type could potentially cause a mismatch in blood types between mother and fetus during pregnancy, with devastating consequences. (Some users may encounter a paywall.)

Why pregnant teachers were banned from classrooms

Until the 1970s, many schools required pregnant teachers to leave the classroom by mid-term. In 1974, the Supreme Court ruled these policies unconstitutional, establishing that women could choose to keep working while pregnant.

Food allergies were first documented more than 4,000 years ago

Although food allergies are on the rise in modern times, they have been documented in written records for thousands of years. More than 3,000 years ago, Chinese emperors advised patients to avoid certain foods, and Hippocrates noted in his work that food could cause serious harm to certain individuals, and even lead to death.

The Rosetta Stone praised the Pharoah Ptolemy V in the 196 BCE

Since its discovery in 1799, 27 other copies have been found throughout Egypt, the most recent in 2011. Dr. Ilona Regulski, curator of ancient writing at the British Museum, discusses the crucial artifact and its specific content.

Two dogs were able to detect prostate cancer in 98% of patients in one study

In this small study published in 2015, two highly trained German Shepherd dogs sniffed hundreds of urine samples and were able to accurately detect prostate cancer—sniffing out certain volatile organic compounds—in almost every single case. One dog was correct 98% of the time and the other correctly identified patients 100% of the time. (Some users may encounter a paywall.)

Ancient Rome had an early version of macaroni and cheese

Called placenta (with a hard "c"), the holiday dish consisted of sheets of rolled-out dough layered with cheese. It is the first recipe documenting the combination of the two elements. While there is debate about whether the dough can be called pasta because it's not boiled, many scholars view the dish as a proto-lasagna.

Some say baseball's drug problem goes back to the late 1800s

At age 32, pitcher James “Pud” Galvin was feeling tired and decided to take "the Brown-Séquard elixir," which contained a testicular fluid from dogs and guinea pigs, believed to invigorate tired bodies. It might've worked: Galvin pitched a two-hit shutout the next day.

The prominent role of women in the Easter story

In the first century, women's testimony was not legally admissible in Jewish courts—the historian Josephus wrote that their accounts were not admissible based on a prejudiced view of women. Scholars who argue for the historical reliability of the resurrection point to this as counterintuitive evidence: no one fabricating the story would have chosen women as the prime witnesses.

Graffiti dates back to at least ancient Pompeii, where citizens scrawled messages to one another on public walls

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Learn more about the history of fireworks, which dates back to an accidental invention during an alchemist's quest for information about immortality.

Stanford built a Google Maps for the Roman Empire, revealing how much it cost to travel in the ancient world

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

In 1963, a basement renovation in Turkey revealed a passageway to a hidden, multilevel underground city that once housed as many as 20,000 people

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

English mathematician Ada Lovelace wrote the first computer algorithm a century before computers existed and hypothesized that computing devices would one day be able to compose music—foreseeing the generative AI systems of today.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

20,000 letters to the advice columnist 'Dear Abby' provide insight into prevailing sex, religion, and LGBTQ fears, anxieties, and concerns from the 1950s onward.

For centuries, it was common to sleep in two shifts: a few hours at the beginning of the night, and a longer period beginning around midnight

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Before humans, the Soviet Union and the United States sent animals—including apes, dogs, and cats—to space during the Space Race.

The 2026 Ebola outbreak is hampered by a lack of vaccine against the species of the virus, heightening the need for rapid tests to aid in disease control.

Long before Major League Baseball began allowing instant replay for balls and strikes, an umpire reluctantly used the technology to determine whether a hit was a home run, a move that inadvertently ushered in a new era for the sport.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

The Brothers Grimm were lawyers before they were storytellers, and became interested in fairy tales as they began investigating how rules and customs had been passed down through cultures.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

Artificial coral reefs have been 3D printed from nontoxic, biodegradable terracotta clay, which coral polyps have used as a foundation for rebuilding marine ecosystems.