There are hundreds of subtypes of cancer, making a universal cure nearly impossible

Explore the National Cancer Institute's archive on treatments

Cancer is a complex disease with many different types, each with its own pathology. The best treatment may depend on characteristics specific to each person—even if two people share the same type of cancer. No single overview of treatments exists, but this resource from the National Cancer Institute lets you explore different options, side effects, an A-to-Z library of cancer drugs, and much more.

Cancer is runaway growth of abnormal, mutated cells

Cancer cells have mutations in their DNA that allow uncontrolled growth and division, dodge usual mechanisms of cell death, and can often spread throughout the body. This is, in part, why the disease is so difficult to treat, with a wide variety of mechanisms and types that poses unique challenges.

Roughly 1 in 5 cancers are caused by viruses

About 20% of cancers are caused by viruses, with seven specific oncoviruses causing between 10% and 15% of cancers worldwide. These include human papillomavirus and hepatitis B and C viruses, which can lead to diseases such as cervical and liver cancer. Understanding the mechanisms of these viruses is crucial for prevention and treatment strategies.

Timeline of cancer research milestones

While cancer remains incurable, there's been so much progress in its treatment over the last two decades. Nature provides an abridged history of milestones and major triumphs in cancer research and treatment. Start in the year 2000, and see how much has changed in the first quarter of the new millennium

Cancer is typically described by one of five stages

Stage 0 is in situ, meaning abnormal cells haven’t spread, while Stage 1 is further progressed but remains localized to the origin. Stage 2 and 3 show increasing tumor size and spread to nearby lymph nodes or tissues. Stage 4 indicates metastasis, meaning cancer has spread to distant organs.

Large animals like giraffes and elephants have evolved unique cancer defenses

One may expect the larger an animal is, the more likely it is to develop cancer—simply because there are more cells and more chances for a dangerous mutation. However, some large animals show cancer rates almost 10 times lower than humans—a phenomenon known as Peto's Paradox.

What is cancer bioengineering?

While new treatments for cancer are under continuous development, researchers are increasingly using engineering principles to find wholly new strategies to combat the disease. Directions include nanoparticle drug delivery, advanced imaging tools, developing new materials to interact with cells, tissue engineering, robotic surgeries, and more. Such interdisciplinary efforts are expected to unlock new tools and therapies beyond traditional drug formulation.

Chemotherapy slows cancer by interfering with cell division

Cancer cells divide much more frequently than most normal cells. Most chemotherapy drugs are designed to interfere with cell division, thereby targeting harmful cells while attempting to leave healthy cells alone.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

The term 'cancer' is 3,000 years old

Around 400 BCE, Hippocrates is said to have named masses of cancerous cells "karkinos"—the Greek word for crab. Science and medical historian Dr. Howard Markel discusses a few hypotheses on why Hippocrates named the disease after a crab and how well cancer was understood in the ancient world.

Many cancers arise from genetic mutations inherited from your parents

These mutations may happen in response to environmental or lifestyle factors, or may be passed down through family members. Genetic testing can be important in catching certain family cancers early and ensuring patients receive the right treatment for their disease.

Advanced drugs are closing in on cancer's deadliest mutations

The protein KRAS, mutated in many cancers, was deemed ‘undruggable’. Now scientists are hoping to save lives with a batch of new compounds that target it.

Teaching immune cells to fight cancer

CAR T-cell therapy is a type of immunotherapy, which involves strengthening the immune system to attack cancer cells. Patient T cells, which manage immune responses and are responsible for killing pathogen-infected cells, are collected and re-engineered to produce surface-level proteins called chimeric antigen receptors. These CARs, now able to bind to specific proteins on cancer cell surfaces, are multiplied into the millions and infused back into the patient.

Explore more statistics about cancer

The American Cancer Society's Cancer Statistics Center estimates there will be more than 2 million new cancer cases and almost 620,000 cancer deaths in the US during the course of 2025. Breast, prostate, and lung cancers remain the most prevalent. This interactive tool provides detailed statistics on cancer incidence, mortality, and survival rates, allowing users to explore data by state, cancer type, demographics, and risk factors.

How race science influences breast cancer research

Despite researchers' and physicians' pushback, race is still used in studies and clinics to categorize human differences in health conditions and treatment responses. This article explores how race has influenced breast cancer research. Considering race as a factor in cancer research, diagnosis, and treatment can lead to racial inequalities. Sociocultural factors, including food access and air pollution, greatly influence health outcomes.

Learn about the more than 100 known autoimmune diseases

Explore this resource with summaries and related resources for the dozens of autoimmune diseases defined in the medical literature. Many of these disease write-ups also have interviews with a patient with the disorder—offering a personal take about challenges, advice, and lifestyle effects.

What are universal vaccines?

As viruses mutate and develop, vaccines have to adapt, leading to regular recommended injections like flu shots. Researchers are working to develop universal vaccines that aim to protect against multiple virus variants if not entire virus families. These vaccines work by creating broadly neutralizing antibodies (bnAbs) that target aspects of viruses that don't typically mutate and are integral to the virus' survival.

Is it possible to cure diabetes?

Treatments for diabetes depend on the type of condition a patient has. Gestational diabetes typically goes away after birth, and those with Type 2 diabetes may be able to reverse their condition through diet, exercise, and blood sugar management. Type 1 diabetes has no cure, but can be successfully managed.

Scientists identify hundreds of genes responsible for OCD

Researchers analyzed the DNA of more than 53,000 people with OCD and identified 30 areas in the genome linked to the disease, containing 249 genes of interest. Of those, several were linked to other brain disorders, paving the way for genetic treatments of various mental illnesses.

More than 200 drug trials for Alzheimer's have failed or been abandoned since 2010

The complexity of Alzheimer's disease, coupled with decades of underfunded research efforts, has left patients with little in the way of effective treatments. In recent years, scientists have synthesized several drugs that studies show can slow the progression of Alzheimer's—though the disease itself remains incurable.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

There is no cure for the general condition of arthritis

While there are innumerable conditions ultimately leading to the joint pain we collectively term "arthritis," one common pathway is progressive inflammation and joint damage many years after an injury.

What is cardiovascular disease?

Cardiovascular diseases are a range of related health conditions that develop in the heart and blood vessels. This article and related infographics detail cardiovascular disease types and treatments.

There are more than a dozen types of different emergency medicine specialties

This video details medical subspecialties in emergency medicine, including medical toxicology, pediatric emergency medicine, undersea and hyperbaric medicine, hospice medicine, and more. It discusses where these types of specialists may work, including beyond a hospital setting.

There are more than 300 different thematic ETFs

Exchange-traded funds seem to offer something for everyone. As tracked by ETF.com, there are 338 thematic ETFs, offering exposure to “baskets” of stocks covering global infrastructure, genomics, cannabis, and more.

Usher Syndrome, a rare genetic disorder, causes progressive hearing and vision loss

People with one of the subtypes of this condition have a genetic mutation that starves cells in the inner ear and the retina of proteins required for detecting sound and light. Gene therapy in animals has seemed like a promising treatment for the condition.

Fantasy has dozens of subgenres

“Fantasy” itself is a rather broad way of characterizing fiction. The genre encompasses many subgenres, including epic (like JRR Tolkein’s “Lord of the Rings”), dark (like Neil Gaiman’s “Coraline”), or even superhero (like your favorite Marvel or DC comics).

Three Ebola species are responsible for most large outbreaks of the disease, yet the only approved Ebola vaccine is known to work against just one of them.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

See how each of the more than two million known species relates to each other—and to common ancestors—in this zoomable tree of life.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

The United States is one of only around two dozen countries with a fully federal system of government, in which power is divided between national and state governments.

Between 10 million and 50 million people in the US develop rashes from poison ivy, poison sumac, and poison oak each year.

Corals are themselves not coral reefs—the term refers to the tiny marine invertebrates that build the rigid reef.

US intelligence allegedly pursued more than 600 schemes to assassinate Cuban revolutionary Fidel Castro.

Chaos theory—informally known as the butterfly effect—is the reason why weather forecasts are presented with probabilities rather than certainties.

All rainbows are 'raincircles' caused by water droplets separating white sunlight into a spectrum of colors, but Earth's surface blocks the bottom half of the circle from our line of sight.

Explore a list of the 100 best novels of all time, compiled by some of the world's best living writers, including Salman Rushdie, Stephen King, and Jennifer Egan.

Search a massive database of over 4 decades of clues from the TV quiz show 'Jeopardy!'

Venture capital is a form of funding provided to early-stage companies with high growth potential, typically in exchange for an equity (or ownership) stake

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

The Dracula character, now seen as the vampire archetype, was inspired by a seafood-induced nightmare its creator experienced.