Learn about the more than 100 known autoimmune diseases

More than 5 million Americans have more than one autoimmune disease

Overall, about 4.6% of the US population—15 million people—have an autoimmune condition. Some common examples include rheumatoid arthritis, psoriasis, type 1 diabetes, Grave's disease, and autoimmune thyroiditis.

Autoimmune diseases affect between 5% and 10% of people worldwide, but their causes remain unknown

Autoantibodies—which attack the body—may be detectable in the body years before a patient develops symptoms, but some people may have detectable levels yet never go on to develop an autoimmune disease. This video discusses this and other unsolved mysteries with autoimmune disease.

How autoimmune diseases, which attack your own tissues and cells, work in the body

These diseases remain some of medicine's thorniest problems because the immune system can mistakenly attack almost any tissue in the body, resulting in myriad diseases, including lupus (numerous tissues affected), Hashimoto's (thyroid), and MS (the nervous system).

Autoimmune disorders are one of the top 10 killers of young and middle-aged women

Studies in the US and the UK, though conducted decades ago, have underscored that autoimmune diseases, when grouped together, are a top killer of women.

How one autoimmune disease patient is questing for inflammation cures

This article's writer, who has Hashimoto's Disease and characteristic symptoms from her body attacking her thyroid—like exhaustion, hair loss, and brain fog—shares big take-aways from an anti-inflammatory retreat in Italy. The writer suggests that a holistic approach to eating, sleeping, and stress management, are the only sustainable ways to lower inflammation.

Why CAR-T therapy has become one of the main focus areas for autoimmune diseases

The therapy, originally targeting cancer, involves taking a patient's own T cells, genetically reprogramming them to recognize and attack a specific target and then infusing them back into patients. For autoimmune diseases, the therapy instead programs them to target immune cells that are causing problems, restoring immune system tolerance.

Common genetic disorders

As research continues, it's clear that disease and genetics go hand in hand. Here's a selection of 50 National Human Genome Research Institute (NHGRI) articles providing basic information on genetic, orphan, and rare diseases caused by mutations in DNA sequences, whether inherited from parents or brought about by outside factors.

The gut microbiome may play a major role in autoimmune disease and symptom flare-ups

Certain unhealthy foods can promote gut bacterial growth and inflammation in the lining of the gut, potentially disrupting its lining—leading to a leaky gut that may allow pathogens to dribble out into the bloodstream, fueling further inflammation that can both cause disease flare-ups and set the stage for future disease development.

Five advancements in arthritis research

It is estimated that nearly 350 million people worldwide are currently suffering from arthritis. This resource explores five of the most promising recent advancements in arthritis research as scientists work towards improved treatments and continue the search for a cure.

Lupus, an autoimmune disease with varied symptoms, was named for wolf bite-like lesions

The 13th-century physician behind the name (lupus is Latin for wolf) named it after a patient he saw who had facial lesions that looked to him like a wolf's bite. Other common symptoms of the disease include extreme fatigue, painful and swollen joints, fevers, and light sensitivity.

GLP-1s are netting interest for treating autoimmune diseases, but are considered experimental

Already used to treat type 2 diabetes, the novel medications are showing some early promise in experimental studies at reducing inflammation and treating autoimmune conditions including rheumatoid arthritis and inflammatory bowel conditions. But researchers caution that side effects are still under investigation—rarely the medication has caused lupus, an autoimmune disease.

Watch patient stories describing life with macular degeneration

This video series features patients discussing their experiences with the disorder, family members describing caregiving, and other insights about the disease.

Explore the National Cancer Institute's archive on treatments

Cancer is a complex disease with many different types, each with its own pathology. The best treatment may depend on characteristics specific to each person—even if two people share the same type of cancer. No single overview of treatments exists, but this resource from the National Cancer Institute lets you explore different options, side effects, an A-to-Z library of cancer drugs, and much more.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Migrane 101: data, symptoms, and treatments

Living with migraine, however often the neurological condition attacks, is a journey fraught with pain and isolation. This migraine guide offers insight into the condition, common triggers, possible treatments, personal stories, and tips for managing life with migraine.

A growing number of autism researchers with the disorder are reshaping the field

People with autism are now leading research on the effects of stigma and discrimination and promoting more studies on public services for autistic people. They also serve as editors, reviewers, and board members on autism academic journals, creating a new chapter in a field littered with painful stereotypes and prejudice.

An encyclopedia of anthropology

This online database offers articles and additional resources for all things anthropology. This free resource is filled with peer-reviewed entries that cover topics ranging from addiction to writing, and offers anthropological insight into more...

A technical review of what researchers know about the gut microbiome

This overview from the National Institutes of Health provides a deeper (but still accessible) look at the different bacteria in the gut, how the microbiome develops through life, its purpose, and more.

What is cardiovascular disease?

Cardiovascular diseases are a range of related health conditions that develop in the heart and blood vessels. This article and related infographics detail cardiovascular disease types and treatments.

Understanding insulin

Scientists Daniel and Kelly talk with researcher Dr. Katrine Whiteson about diabetes, the history of insulin production, and Dr. Lydia Villa-Komaroff—an essential member of the team who discovered that bacteria could be induced to produce insulin. Listen to discover interesting facts about the life-saving medicine and how it works in the human body.

What is the immune system? A quick 101

Your body’s immune system is designed to protect you from infection. Find out more about how the immune system works with this quick overview and set of diagrams.

Animal-to-human pathogens constitute 75% of emerging infectious diseases

Zoonotic diseases encompass more than 200 diseases transmitted from animals to humans, wherein humans are usually accidental hosts. Ranging from rabies to HIV to monkeypox, this overview lists some of the most common viral threats.

Find dozens of allergen-free recipes

This collection of allergen-free meal and snack recipes, designed by celebrity chefs and others, was curated by the nonprofit Food and Allergy Research & Education group. It includes items like taquitos, pizza, chickpea burgers, various desserts, and more.

The potential promises and pitfalls of AI in medicine

Artificial intelligence (AI) is increasingly being integrated into healthcare, offering the potential to aid in diagnoses, answer patient queries, and streamline administrative processes. In a recent PBS interview, Dr. Isaac Kohane, editor-in-chief of the New England Journal of Medicine AI and chair of Harvard’s department of biomedical informatics, discusses the current state and future of AI in medicine.

Understanding vaccine side effects

A vaccine is a medical intervention, and as with any medical intervention, may have side effects. This article discusses side effects and adverse events related to vaccination.

Support groups are typically free, which makes them widely accessible

The groups are typically run by someone with the same illness or set of experiences and can provide clear, practical knowledge about navigating healthcare resources, bureaucracy, and more. Since they function on trust, however, there are no legal confidentiality prohibiting people from sharing what's discussed. What's more, group leaders may not be uniformly trained or certified.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

See how each of the more than two million known species relates to each other—and to common ancestors—in this zoomable tree of life.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

This poison ivy knowledge quiz—accompanied by photos of the plant's varied forms—may help you identify this common rash-inducing growth.

20,000 letters to the advice columnist 'Dear Abby' provide insight into prevailing sex, religion, and LGBTQ fears, anxieties, and concerns from the 1950s onward.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

This site reaches millions of visitors who are tired of AI chatbots and seeking human connection. Pretend to be an AI chatbot and ask questions, provide answers, and draw for people in real time.

Explore what it's like inside a patient isolation unit, used in situations such as treating a patient or suspected patient with Ebola.

Explore the known asteroids, comets, and spacecraft involved in asteroid studies within our solar system with 'Eyes on Asteroids,' a 3D visualization from NASA.

Explore an interactive map of battles from the American Revolution, along with detailed summaries of each engagement

See these 16 pieces of art evoking phobias of snakes, flying, spiders, and more. 

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

Explore a list of the 100 best novels of all time, compiled by some of the world's best living writers, including Salman Rushdie, Stephen King, and Jennifer Egan.

View the ten deadliest tornadoes in US history.

The United States is one of only around two dozen countries with a fully federal system of government, in which power is divided between national and state governments.

Use this tool to calculate the dollar value of your parental mental load, from meal planning to coordinating after-school care, then see resources that help generate solutions.

The first steps to rebuilding your credit score include getting to know exactly what's on your credit report and figuring out how far you are from the '700 club,' or 'good score' range.

See a 3D reconstruction of Tenochtitlan, the Aztec capital that was home to an estimated population of 200,000 to 400,000.