Chemotherapy slows cancer by interfering with cell division

Immunotherapy focuses on boosting the immune system to fight cancer

The immune system detects and destroys abnormal cells, curbing the growth of many cancers. Immunotherapy works to boost the body’s immune system to target and kill cancer cells. There are many ways to accomplish this, including adaptive cell therapy, checkpoint inhibitors, vaccines, and monoclonal antibodies.

Cells become cancerous if checkpoints in the cell cycle are damaged

Before cells divide, a protein called p53 can halt the cell cycle if damaged DNA is identified, preventing the fault from propagating to daughter cells. If p53 and other tumor-suppressing molecules cannot function due to mutations or other instabilities, damage can accumulate over successive generations until nothing stops cells from dividing uncontrollably, creating tumors.

Cancer is runaway growth of abnormal, mutated cells

Cancer cells have mutations in their DNA that allow uncontrolled growth and division, dodge usual mechanisms of cell death, and can often spread throughout the body. This is, in part, why the disease is so difficult to treat, with a wide variety of mechanisms and types that poses unique challenges.

Low cell division rates in heart cells make heart cancer particularly rare

The heart's location in the chest also offers protection from external cancer-causing factors. The disease affects about 3 in every 10,000 people, though most cases arise from metastasis from other body parts.

See how CAR-T cell therapy works to help fight cancer

Short for chimeric antigen receptor T-cell therapy, CAR-T Cell Therapy helps augment the body's own ability to attack cancer cells. It's a cell-based gene therapy that alters the genes in a person's T cells—which are a type of immune cell—to help them beat back cancerous growths.

What is cancer bioengineering?

While new treatments for cancer are under continuous development, researchers are increasingly using engineering principles to find wholly new strategies to combat the disease. Directions include nanoparticle drug delivery, advanced imaging tools, developing new materials to interact with cells, tissue engineering, robotic surgeries, and more. Such interdisciplinary efforts are expected to unlock new tools and therapies beyond traditional drug formulation.

How does cancer actually kill someone?

While the emotional and physical tolls of cancer are often clear, the innerworkings of how cancer kills can be confusing — and terrifying to discuss. Here, oncologists explain how cancer can progress.

There are hundreds of subtypes of cancer, making a universal cure nearly impossible

Cancer is an umbrella term for over 200 different diseases, each with its own subtypes, genetic mutations, and behaviors. This diversity means that a treatment effective for one cancer type or patient may be ineffective for others. Moreover, as tumors grow, their cells accumulate different mutations, creating subclones with unique characteristics.

Combining two cancer drugs increased the life space of mice by 30%

A study shows trametinib and rapamycin, two drugs used for cancer treatment in humans, increased mouse lifespan when used together. The medications delayed the onset of cancer and reduced chronic inflammation, results that will be explored in future research.

Explore the differences between healthy and cancerous cells using a DNA microarray

In this simulation, you will learn how scientists use microarrays to experiment on thousands of genes at the same time. By determining which genes are on or off, users can identify those that contribute to cancer formation.

Lung cancer advances are making a big difference

Lung cancer deaths are declining faster than new cases due to advances in treatment. The progress illustrates what is possible, even for a cancer that has long had a poor prognosis.

The HPV vaccine reduces cervical cancer rates by 90% or more

Cervical cancer is the fourth most common cancer in women globally. Almost all cases (99%) are linked to infection with high-risk human papillomaviruses. However, cervical cancer is both treatable and preventable—and we may be able to prevent most cases through vaccination.

Cancer rates are on the rise among GenXers and Millennials

Cancer rates are rising among Gen X and Millennials, with more cancer diagnoses being made in their 30s and 40s than previous generations. Factors such as prenatal exposures, environmental toxins, and lifestyle choices may contribute to this trend. Memorial Sloan Kettering Cancer Center's experts discuss these issues, exploring how these insights could reshape cancer risk understanding.

Treatment-induced menopause is menopause induced by surgery or medicine

Chemotherapy and radiation, as well as oophorectomy (a surgical procedure that removes the ovaries) and a radical hysterectomy can cause a woman to become menopausal. Women that go through medical menopause experience the same symptoms as women that experience menopause caused by natural hormonal cycles.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Alcohol is responsible for 5% of cancer cases and 4% of cancer deaths in the US

Alcohol consumption is linked to at least eight different types of cancer, including liver, breast, and throat. The risk comes from ethanol, which turns into DNA-damaging acetaldehyde. Experts recommend limiting intake or quitting altogether to reduce long-term health risks.

The most common type of particle accelerator is a linear electron accelerator

Known as linacs, these devices fire particles in a straight line, making them useful for the intense, targeted beams needed in cancer treatment. Circular accelerators, such as synchrotrons and cyclotrons, can achieve extremely high particle speeds through repeated exposure to electromagnetic fields.

Steve Jobs tried to treat his cancer with alternative medicine

After Steve Jobs was diagnosed with pancreatic cancer, he reportedly restricted his diet to just fruits or just fruits and vegetables, tried out hydrotherapy, and consulted psychics. There’s compelling evidence about the impact of alternative medicine on cancer patients.

Computer viruses can slow systems by allocating resources to malicious actions

Once infected software is run, instructions in the malicious code within the program or file can copy the code to various locations, exacerbating the infection and producing additional symptoms, such as slow performance, altered login credentials, changes to device settings, and system crashes.

Penicillin works by attacking the cell walls of bacteria

Penicillin targets bacteria at their weakest point—their cell walls. By blocking wall-building, it leaves microbes unable to survive, causing them to burst and die.

Blood clotting is critical to maintaining life, but dysfunctional clots can be fatal

Clotting is how our body stops bleeding in the event of an injury. Typically, platelets adhere to exposed tissue, becoming sticky and forming a plug. Chemical signals trigger the coagulation cascade, converting fibrinogen into fibrin threads that stabilize the plug. This prevents bleeding but can obstruct vessels if overactive or misplaced.

Cells modify their internal spacing to improve biochemical reaction efficiencies

Studies involving microscopy and genetic engineering tools in yeast and human cells show ribosomes act as crowding agents—much like packing peanuts—and their concentrations are actively tuned to alter the rate of cellular functions. However, these concentrations and cell crowding levels vary across different tissues and cell types.

Humanity's reduced body hair slows down wound healing

Cuts to human skin take twice as long to heal compared to chimps and other mammals. Scientists argue this is due to the reduced number of hair follicles on human bodies. Hair follicles contain stem cells which help repair skin cells faster, so as humanity shed its hair over time, so to speak, it also slowed its wound healing.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Mineral and chemical sunscreens protect differently but both guard against UV damage

UVA rays age the skin, while UVB rays are more directly linked to skin cancer. Mineral sunscreens, with ingredients like zinc oxide, physically block rays, while chemical ones absorb UV and turn it into heat.

Catalysts increase chemical reaction rates by providing a lower energy pathway

All chemical reactions must overcome an energy barrier, called an activation energy, to proceed. If insufficient thermal energy exists in the system to overcome the barrier, catalysts can effectively lower the activation energy, increasing the likelihood of reactions occurring.

Vitamins can slow macular degeneration

Research published in 2022 affirmed that vitamin formulations containing vitamins C and E, copper, zinc, lutein, and zeaxanthin—but no beta carotene—can enhance eye health and slow the progression of macular degeneration.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

Ebola infects and disables immune cells, triggering a cascade of events that leads to small blood clots throughout the body, weakening blood vessels and interrupting blood flow to key organs.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

How fusion—which releases energy when two lighter atoms combine to form a heavier atom—differs from fission

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Scientists testing how climate change affects plants found, in a years-long simulation study, that poison ivy grew 70% faster with the resulting extra carbon dioxide.

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

US intelligence allegedly pursued more than 600 schemes to assassinate Cuban revolutionary Fidel Castro.

Firework or sparkler burns, even if they cover a relatively small area of skin, can significantly affect our range of motion.

Coral polyps reproduce via broadcast spawning, where entire reefs simultaneously release reproductive cells for about one hour, once a year.

Chaos theory—informally known as the butterfly effect—is the reason why weather forecasts are presented with probabilities rather than certainties.

Hedge funds, the private investment firms that trade a wide swath of financial assets, make money by imposing steep fees on investors and from the fund's investment performance.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.

Power lines are dotted with large, brightly colored balls to improve the visibility of these thin wires to helicopters and small planes and help prevent potential crashes.

Iran's Revolutionary Guard Corps is independent of Iran's regular army and is one of the most powerful and influential military-political organizations in the Middle East.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.